المؤلفون: Pedram K; Department of Chemistry and Sarafan ChEM-H, Stanford University, Stanford, CA, USA.; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA., Shon DJ; Department of Chemistry and Sarafan ChEM-H, Stanford University, Stanford, CA, USA., Tender GS; Department of Chemistry and Sarafan ChEM-H, Stanford University, Stanford, CA, USA., Mantuano NR; Cancer Immunotherapy Laboratory, Department of Biomedicine, University of Basel, Basel, Switzerland.; Division of Oncology, Department of Theragnostics, University Hospital, Basel, Switzerland., Northey JJ; Center for Bioengineering and Tissue Regeneration, Department of Surgery, University of California, San Francisco (UCSF), San Francisco, CA, USA., Metcalf KJ; Center for Bioengineering and Tissue Regeneration, Department of Surgery, University of California, San Francisco (UCSF), San Francisco, CA, USA., Wisnovsky SP; Department of Chemistry and Sarafan ChEM-H, Stanford University, Stanford, CA, USA.; Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada., Riley NM; Department of Chemistry and Sarafan ChEM-H, Stanford University, Stanford, CA, USA., Forcina GC; Department of Chemistry and Sarafan ChEM-H, Stanford University, Stanford, CA, USA., Malaker SA; Department of Chemistry and Sarafan ChEM-H, Stanford University, Stanford, CA, USA.; Department of Chemistry, Yale University, New Haven, CT, USA., Kuo A; Department of Chemistry and Sarafan ChEM-H, Stanford University, Stanford, CA, USA., George BM; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Brigham and Women's Hospital, Boston, MA, USA., Miller CL; Department of Chemistry and Sarafan ChEM-H, Stanford University, Stanford, CA, USA., Casey KM; Department of Comparative Medicine, Stanford University, Stanford, CA, USA., Vilches-Moure JG; Department of Comparative Medicine, Stanford University, Stanford, CA, USA., Ferracane MJ; Department of Chemistry, University of Redlands, Redlands, CA, USA., Weaver VM; Center for Bioengineering and Tissue Regeneration, Department of Surgery, University of California, San Francisco (UCSF), San Francisco, CA, USA.; Departments of Radiation Oncology and Bioengineering and Therapeutic Sciences, Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, and Helen Diller Comprehensive Cancer Center, University of California, San Francisco (UCSF), San Francisco, CA, USA., Läubli H; Cancer Immunotherapy Laboratory, Department of Biomedicine, University of Basel, Basel, Switzerland.; Division of Oncology, Department of Theragnostics, University Hospital, Basel, Switzerland., Bertozzi CR; Department of Chemistry and Sarafan ChEM-H, Stanford University, Stanford, CA, USA. bertozzi@stanford.edu.; Howard Hughes Medical Institute, Stanford, CA, USA. bertozzi@stanford.edu.

المصدر: Nature biotechnology [Nat Biotechnol] 2024 Apr; Vol. 42 (4), pp. 597-607. Date of Electronic Publication: 2023 Aug 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1696 (Electronic) Linking ISSN: 10870156 NLM ISO Abbreviation: Nat Biotechnol Subsets: MEDLINE

مواضيع طبية MeSH: Mucins*/metabolism , Neoplasms*, Animals ; Mice ; Peptide Hydrolases/metabolism ; Proteolysis

المؤلفون: Forcina GC; Department of Biology, Stanford University, Stanford, CA 94305., Pope L; Department of Biology, Stanford University, Stanford, CA 94305., Murray M; Department of Biology, Stanford University, Stanford, CA 94305., Dong W; Department of Chemical Engineering, Stanford University, Stanford, CA 94305.; Stanford ChEM-H, Stanford University, Stanford, CA 94305., Abu-Remaileh M; Department of Chemical Engineering, Stanford University, Stanford, CA 94305.; Stanford ChEM-H, Stanford University, Stanford, CA 94305., Bertozzi CR; Stanford ChEM-H, Stanford University, Stanford, CA 94305.; Department of Chemistry, Stanford University, Stanford, CA 94305.; HHMI, Stanford University, Stanford, CA 94305., Dixon SJ; Department of Biology, Stanford University, Stanford, CA 94305.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Mar 15; Vol. 119 (11), pp. e2118646119. Date of Electronic Publication: 2022 Mar 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Ferroptosis*/genetics , Gene Expression Regulation* , NF-E2-Related Factor 1*/genetics , NF-E2-Related Factor 1*/metabolism , Oxidative Stress*/genetics , Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase*/genetics , Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase*/metabolism , Phospholipid Hydroperoxide Glutathione Peroxidase*/genetics, Gene Knockout Techniques ; Humans ; Lipid Peroxidation ; Metabolic Networks and Pathways/genetics

المؤلفون: Johnson FD; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada; Interdisciplinary Oncology Program, University of British Columbia, Vancouver, BC, Canada; Canada's Michael Smith Genome Sciences Centre, BC Cancer Research Institute, Vancouver, BC, Canada., Ferrarone J; Meyer Cancer Centre, Weill Cornell Medicine, New York City, NY, USA., Liu A; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada., Brandstädter C; Department of Biochemistry and Molecular Biology, Justus Liebig University Giessen, Giessen, Germany., Munuganti R; Department of Urologic Sciences, University of British Columbia, Vancouver, BC, Canada., Farnsworth DA; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada; Interdisciplinary Oncology Program, University of British Columbia, Vancouver, BC, Canada., Lu D; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada; Interdisciplinary Oncology Program, University of British Columbia, Vancouver, BC, Canada., Luu J; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada; Department of Pathology & Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada., Sihota T; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada; Department of Pathology & Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada., Jansen S; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada., Nagelberg A; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada; Department of Pathology & Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada., Shi R; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada; Interdisciplinary Oncology Program, University of British Columbia, Vancouver, BC, Canada., Forcina GC; Department of Biology, Stanford University, Stanford, CA, USA., Zhang X; Thoracic and GI Malignancies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA., Cheng GSW; Canada's Michael Smith Genome Sciences Centre, BC Cancer Research Institute, Vancouver, BC, Canada., Spencer Miko SE; Canada's Michael Smith Genome Sciences Centre, BC Cancer Research Institute, Vancouver, BC, Canada., de Rappard-Yuswack G; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada., Sorensen PH; Department of Pathology & Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada., Dixon SJ; Department of Biology, Stanford University, Stanford, CA, USA., Guha U; Thoracic and GI Malignancies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA., Becker K; Department of Biochemistry and Molecular Biology, Justus Liebig University Giessen, Giessen, Germany., Djaballah H; High Throughput Screening Core Facility, Memorial Sloan-Kettering Cancer Center, New York City, NY, USA; Keren Therapeutics, New York City, NY, USA., Somwar R; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York City, NY, USA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Varmus H; Meyer Cancer Centre, Weill Cornell Medicine, New York City, NY, USA., Morin GB; Canada's Michael Smith Genome Sciences Centre, BC Cancer Research Institute, Vancouver, BC, Canada; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada., Lockwood WW; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada; Interdisciplinary Oncology Program, University of British Columbia, Vancouver, BC, Canada; Department of Pathology & Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada. Electronic address: wlockwood@bccrc.ca.

المصدر: Cell reports [Cell Rep] 2022 Feb 08; Vol. 38 (6), pp. 110343.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Lung Neoplasms/*pathology , Oxidative Stress/*physiology , Oxidoreductases/*metabolism , Thioredoxin-Disulfide Reductase/*metabolism, Glutathione/metabolism ; Humans ; Lung/metabolism ; Lung/pathology ; Lung Neoplasms/metabolism ; Reactive Oxygen Species/metabolism ; Thioredoxins/metabolism

المؤلفون: Conlon M; Department of Biology, Stanford University, Stanford, CA, USA., Poltorack CD; Department of Biology, Stanford University, Stanford, CA, USA., Forcina GC; Department of Biology, Stanford University, Stanford, CA, USA., Armenta DA; Department of Biology, Stanford University, Stanford, CA, USA., Mallais M; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, ON, Canada., Perez MA; School of Molecular Biosciences and Center for Reproductive Biology, Washington State University, Pullman, WA, USA., Wells A; Department of Biology, Stanford University, Stanford, CA, USA., Kahanu A; Department of Biology, Stanford University, Stanford, CA, USA., Magtanong L; Department of Biology, Stanford University, Stanford, CA, USA., Watts JL; School of Molecular Biosciences and Center for Reproductive Biology, Washington State University, Pullman, WA, USA., Pratt DA; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, ON, Canada., Dixon SJ; Department of Biology, Stanford University, Stanford, CA, USA. sjdixon@stanford.edu.

المصدر: Nature chemical biology [Nat Chem Biol] 2021 Jun; Vol. 17 (6), pp. 665-674. Date of Electronic Publication: 2021 Mar 08.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Ferroptosis/*physiology, Amino Acids/metabolism ; Animals ; Antioxidants/pharmacology ; Apoptosis/drug effects ; Cell Death/drug effects ; Cell-Free System ; Humans ; Indoles/pharmacology ; Iron Chelating Agents/pharmacology ; Kinetics ; Small Molecule Libraries ; TOR Serine-Threonine Kinases/antagonists & inhibitors

المؤلفون: Inde Z; Department of Biology, Stanford University, Stanford, CA 94305, USA., Forcina GC; Department of Biology, Stanford University, Stanford, CA 94305, USA., Denton K; Department of Biology, Stanford University, Stanford, CA 94305, USA., Dixon SJ; Department of Biology, Stanford University, Stanford, CA 94305, USA. Electronic address: sjdixon@stanford.edu.

المصدر: Cell reports [Cell Rep] 2020 Jul 07; Vol. 32 (1), pp. 107845.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Apoptosis*, Neoplasms/*pathology, Cell Line ; Cell Line, Tumor ; Female ; High-Throughput Screening Assays ; Humans ; Kinetics ; Male ; Mitogen-Activated Protein Kinase Kinases/antagonists & inhibitors ; Myeloid Cell Leukemia Sequence 1 Protein/metabolism ; Protein Kinase Inhibitors/pharmacology ; Time Factors

المؤلفون: Forcina GC; Department of Biology, Stanford University, Stanford, CA, 94305, USA., Dixon SJ; Department of Biology, Stanford University, Stanford, CA, 94305, USA.

المصدر: Proteomics [Proteomics] 2019 Sep; Vol. 19 (18), pp. e1800311. Date of Electronic Publication: 2019 May 31.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101092707 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1615-9861 (Electronic) Linking ISSN: 16159853 NLM ISO Abbreviation: Proteomics Subsets: MEDLINE

مواضيع طبية MeSH: Ferroptosis* , Homeostasis*, Lipids/*physiology , Phospholipid Hydroperoxide Glutathione Peroxidase/*metabolism, Animals ; Humans ; Lipid Peroxidation ; Oxidation-Reduction ; Reactive Oxygen Species/metabolism

المؤلفون: Magtanong L; Department of Biology, Stanford University, Stanford, CA 94305, USA., Ko PJ; Department of Biology, Stanford University, Stanford, CA 94305, USA., To M; Department of Nutritional Sciences and Toxicology, University of California, Berkeley, Berkeley, CA 94720, USA., Cao JY; Department of Biology, Stanford University, Stanford, CA 94305, USA., Forcina GC; Department of Biology, Stanford University, Stanford, CA 94305, USA., Tarangelo A; Department of Biology, Stanford University, Stanford, CA 94305, USA., Ward CC; Departments of Chemistry and Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA., Cho K; Departments of Chemistry and Medicine, Washington University, St. Louis, MO 63130, USA., Patti GJ; Departments of Chemistry and Medicine, Washington University, St. Louis, MO 63130, USA., Nomura DK; Department of Nutritional Sciences and Toxicology, University of California, Berkeley, Berkeley, CA 94720, USA; Departments of Chemistry and Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA., Olzmann JA; Department of Nutritional Sciences and Toxicology, University of California, Berkeley, Berkeley, CA 94720, USA., Dixon SJ; Department of Biology, Stanford University, Stanford, CA 94305, USA. Electronic address: sjdixon@stanford.edu.

المصدر: Cell chemical biology [Cell Chem Biol] 2019 Mar 21; Vol. 26 (3), pp. 420-432.e9. Date of Electronic Publication: 2019 Jan 24.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Fatty Acids, Monounsaturated/*pharmacology , Ferroptosis/*drug effects , Lipids/*chemistry, Animals ; Arachidonic Acid/chemistry ; Arachidonic Acid/metabolism ; Arachidonic Acid/pharmacology ; Cell Line ; Cell Membrane/chemistry ; Cell Membrane/metabolism ; Coenzyme A Ligases/metabolism ; Fatty Acids, Monounsaturated/chemistry ; Fatty Acids, Monounsaturated/metabolism ; Lipid Droplets/chemistry ; Lipid Droplets/metabolism ; Mice ; Oxidation-Reduction ; Phospholipid Hydroperoxide Glutathione Peroxidase/genetics ; Phospholipid Hydroperoxide Glutathione Peroxidase/metabolism ; Reactive Oxygen Species/chemistry ; Reactive Oxygen Species/metabolism

المؤلفون: Forcina GC; Department of Biology, Stanford University, Room 104, 337 Campus Drive, Stanford, CA 94305, USA., Conlon M; Department of Biology, Stanford University, Room 104, 337 Campus Drive, Stanford, CA 94305, USA., Wells A; Department of Biology, Stanford University, Room 104, 337 Campus Drive, Stanford, CA 94305, USA., Cao JY; Department of Biology, Stanford University, Room 104, 337 Campus Drive, Stanford, CA 94305, USA., Dixon SJ; Department of Biology, Stanford University, Room 104, 337 Campus Drive, Stanford, CA 94305, USA. Electronic address: sjdixon@stanford.edu.

المصدر: Cell systems [Cell Syst] 2017 Jun 28; Vol. 4 (6), pp. 600-610.e6. Date of Electronic Publication: 2017 Jun 07.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101656080 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2405-4712 (Print) Linking ISSN: 24054712 NLM ISO Abbreviation: Cell Syst Subsets: MEDLINE

مواضيع طبية MeSH: Cell Death/*physiology , Mammals/*physiology, A549 Cells ; Animals ; Biomarkers/metabolism ; Cell Line, Tumor ; Humans ; Kinetics ; Mammals/metabolism

المؤلفون: Forcina GC; Department of Molecular Biophysics and Biochemistry, Yale University , 260 Whitney Avenue, New Haven, Connecticut 06520-8114, United States., Castro A; Molecular Targets Laboratory, Center for Cancer Research, National Cancer Institute , Frederick, Maryland 21702-1201, United States., Bokesch HR; Molecular Targets Laboratory, Center for Cancer Research, National Cancer Institute , Frederick, Maryland 21702-1201, United States.; Basic Science Program, Leidos Biomedical Research, Inc., Frederick National Laboratory , Frederick, Maryland 21702-1201, United States., Spakowicz DJ; Department of Molecular Biophysics and Biochemistry, Yale University , 260 Whitney Avenue, New Haven, Connecticut 06520-8114, United States., Legaspi ME; Department of Molecular Biophysics and Biochemistry, Yale University , 260 Whitney Avenue, New Haven, Connecticut 06520-8114, United States., Kucera K; Department of Molecular Biophysics and Biochemistry, Yale University , 260 Whitney Avenue, New Haven, Connecticut 06520-8114, United States., Villota S; Laboratorio de Biotecnología Vegetal, Pontificia Universidad Católica del Ecuador , Quito 17 01 21 84, Ecuador., Narváez-Trujillo A; Laboratorio de Biotecnología Vegetal, Pontificia Universidad Católica del Ecuador , Quito 17 01 21 84, Ecuador., McMahon JB; Molecular Targets Laboratory, Center for Cancer Research, National Cancer Institute , Frederick, Maryland 21702-1201, United States., Gustafson KR; Molecular Targets Laboratory, Center for Cancer Research, National Cancer Institute , Frederick, Maryland 21702-1201, United States., Strobel SA; Department of Molecular Biophysics and Biochemistry, Yale University , 260 Whitney Avenue, New Haven, Connecticut 06520-8114, United States.

المصدر: Journal of natural products [J Nat Prod] 2015 Dec 24; Vol. 78 (12), pp. 3005-10. Date of Electronic Publication: 2015 Dec 14.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Society of Pharmacognosy Country of Publication: United States NLM ID: 7906882 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6025 (Electronic) Linking ISSN: 01633864 NLM ISO Abbreviation: J Nat Prod Subsets: MEDLINE

مواضيع طبية MeSH: Sesquiterpenes/*isolation & purification, Anti-Bacterial Agents/pharmacology ; Ecuador ; Endophytes ; Microbial Sensitivity Tests ; Molecular Structure ; Nuclear Magnetic Resonance, Biomolecular ; Polymers ; Sesquiterpenes/chemistry ; Sesquiterpenes/pharmacology ; Staphylococcus aureus/drug effects