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1دورية أكاديمية
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2دورية أكاديمية
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3دورية أكاديمية
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4دورية أكاديمية
المؤلفون: Fotsing JR; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States., Darmohusodo V; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States., Patron AP; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States., Ching BW; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States., Brady T; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States., Arellano M; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States., Chen Q; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States., Davis TJ; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States., Liu H; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States., Servant G; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States., Zhang L; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States., Williams M; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States., Saganich M; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States., Ditschun T; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States., Tachdjian C; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States., Karanewsky DS; Firmenich SA, R&D North America, San Diego site, 4767 Nexus Centre Drive, San Diego, California 92121, United States.
المصدر: Journal of medicinal chemistry [J Med Chem] 2020 May 14; Vol. 63 (9), pp. 4957-4977. Date of Electronic Publication: 2020 Apr 24.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
مواضيع طبية MeSH: Hydantoins/*pharmacology , Pyrazoles/*pharmacology , Receptors, Cell Surface/*antagonists & inhibitors , Receptors, G-Protein-Coupled/*antagonists & inhibitors , Taste/*drug effects, Animals ; Coffee/chemistry ; Drug Discovery ; Drug Stability ; Humans ; Hydantoins/chemical synthesis ; Hydantoins/toxicity ; Molecular Structure ; Pyrazoles/chemical synthesis ; Pyrazoles/toxicity ; Rats ; Structure-Activity Relationship
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5دورية أكاديمية
المؤلفون: Karanewsky DS; Senomyx, Inc., 4767 Nexus Centre Drive, San Diego, CA 92121, United States., Servant G; Senomyx, Inc., 4767 Nexus Centre Drive, San Diego, CA 92121, United States., Liu H; Senomyx, Inc., 4767 Nexus Centre Drive, San Diego, CA 92121, United States., Chi B; Senomyx, Inc., 4767 Nexus Centre Drive, San Diego, CA 92121, United States., Ida L; Senomyx, Inc., 4767 Nexus Centre Drive, San Diego, CA 92121, United States., Saganich M; Senomyx, Inc., 4767 Nexus Centre Drive, San Diego, CA 92121, United States., Werner S; Senomyx, Inc., 4767 Nexus Centre Drive, San Diego, CA 92121, United States., Fotsing JR; Senomyx, Inc., 4767 Nexus Centre Drive, San Diego, CA 92121, United States., Patron A; Senomyx, Inc., 4767 Nexus Centre Drive, San Diego, CA 92121, United States., Tachdjian C; Senomyx, Inc., 4767 Nexus Centre Drive, San Diego, CA 92121, United States., Arthur A; Senomyx, Inc., 4767 Nexus Centre Drive, San Diego, CA 92121, United States.
المصدر: Toxicology reports [Toxicol Rep] 2017 Sep 14; Vol. 4, pp. 507-520. Date of Electronic Publication: 2017 Sep 14 (Print Publication: 2017).
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Elsevier Ireland Ltd Country of Publication: Ireland NLM ID: 101630272 Publication Model: eCollection Cited Medium: Print ISSN: 2214-7500 (Print) Linking ISSN: 22147500 NLM ISO Abbreviation: Toxicol Rep Subsets: PubMed not MEDLINE
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6دورية أكاديمية
المؤلفون: Yamauchi JG; Department of Pharmacology, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, California, USA., Gomez K, Grimster N, Dufouil M, Nemecz A, Fotsing JR, Ho KY, Talley TT, Sharpless KB, Fokin VV, Taylor P
المصدر: Molecular pharmacology [Mol Pharmacol] 2012 Oct; Vol. 82 (4), pp. 687-99. Date of Electronic Publication: 2012 Jul 11.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
بيانات الدورية: Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0035623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0111 (Electronic) Linking ISSN: 0026895X NLM ISO Abbreviation: Mol Pharmacol Subsets: MEDLINE
مواضيع طبية MeSH: Carrier Proteins/*chemistry , Nicotinic Agonists/*chemical synthesis , Receptors, Nicotinic/*metabolism, Alkynes/chemical synthesis ; Alkynes/chemistry ; Alkynes/pharmacology ; Animals ; Aplysia ; Azides/chemical synthesis ; Azides/chemistry ; Azides/pharmacology ; Carrier Proteins/genetics ; Cell Line ; Click Chemistry ; Humans ; Lymnaea ; Mice ; Mutation ; Nicotinic Agonists/chemistry ; Nicotinic Agonists/pharmacology ; Nicotinic Antagonists/chemical synthesis ; Nicotinic Antagonists/chemistry ; Nicotinic Antagonists/pharmacology ; Radioligand Assay ; Stereoisomerism ; Structure-Activity Relationship ; Triazoles/chemical synthesis ; Triazoles/chemistry ; Triazoles/pharmacology ; Tropanes/chemical synthesis ; Tropanes/chemistry ; Tropanes/pharmacology ; alpha7 Nicotinic Acetylcholine Receptor
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7دورية أكاديمية
المؤلفون: Grimster NP; Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA., Stump B, Fotsing JR, Weide T, Talley TT, Yamauchi JG, Nemecz Á, Kim C, Ho KY, Sharpless KB, Taylor P, Fokin VV
المصدر: Journal of the American Chemical Society [J Am Chem Soc] 2012 Apr 18; Vol. 134 (15), pp. 6732-40. Date of Electronic Publication: 2012 Apr 06.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE
مواضيع طبية MeSH: Cholinergic Agents/*chemical synthesis , Receptors, Nicotinic/*metabolism, Acetylcholine/metabolism ; Carrier Proteins/metabolism ; Click Chemistry ; Ligands
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8دورية أكاديمية
المؤلفون: Kwok SW; The Scripps Research Institute, La Jolla, California 92037, USA., Fotsing JR, Fraser RJ, Rodionov VO, Fokin VV
المصدر: Organic letters [Org Lett] 2010 Oct 01; Vol. 12 (19), pp. 4217-9.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 100890393 Publication Model: Print Cited Medium: Internet ISSN: 1523-7052 (Electronic) Linking ISSN: 15237052 NLM ISO Abbreviation: Org Lett Subsets: MEDLINE
مواضيع طبية MeSH: Triazoles/*chemical synthesis, Catalysis ; Hydroxides/chemistry ; Molecular Structure ; Transition Elements/chemistry
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9دورية أكاديمية
المؤلفون: Weide T; Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla CA 92037, USA., Saldanha SA, Minond D, Spicer TP, Fotsing JR, Spaargaren M, Frère JM, Bebrone C, Sharpless KB, Hodder PS, Fokin VV
المصدر: ACS medicinal chemistry letters [ACS Med Chem Lett] 2010 Jul 08; Vol. 1 (4), pp. 150-154.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: Print Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE
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10دورية أكاديمية
المؤلفون: Minond D; Lead Identification, Translational Research Institute, The Scripps Research Institute, Scripps Florida, 130 Scripps Way #1A1, Jupiter, 33458 FL, USA., Saldanha SA, Subramaniam P, Spaargaren M, Spicer T, Fotsing JR, Weide T, Fokin VV, Sharpless KB, Galleni M, Bebrone C, Lassaux P, Hodder P
المصدر: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2009 Jul 15; Vol. 17 (14), pp. 5027-37. Date of Electronic Publication: 2009 Jun 22.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE
مواضيع طبية MeSH: beta-Lactamase Inhibitors*, Enzyme Inhibitors/*pharmacology , Escherichia coli/*drug effects , Small Molecule Libraries/*pharmacology , beta-Lactamases/*metabolism, Analgesics/pharmacology ; Anti-Bacterial Agents/pharmacology ; Catalytic Domain ; Drug Synergism ; Enzyme Inhibitors/chemical synthesis ; Enzyme Inhibitors/chemistry ; Escherichia coli/enzymology ; Imipenem/pharmacology ; Microbial Sensitivity Tests ; Mitoxantrone/pharmacology ; Models, Molecular ; Protein Binding ; Small Molecule Libraries/chemical synthesis ; Small Molecule Libraries/chemistry ; beta-Lactamases/chemistry ; p-Chloromercuribenzoic Acid/pharmacology