المؤلفون: Christel Logez, Sylvie Berger, Céline Legros, Jean-Louis Banères, William Cohen, Philippe Delagrange, Olivier Nosjean, Jean A Boutin, Gilles Ferry, Frédéric Simonin, Renaud Wagner

المصدر: PLoS ONE, Vol 9, Iss 6, p e100616 (2014)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24959712/pdf/?tool=EBI; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/961a2e8080f24c94a99bea2e9fb8eaad

المؤلفون: Gabrielle Zeder-Lutz, Olivier Bornert, Rosine Fellmann-Clauss, Adeline Knittel-Obrecht, Thibaud Tranchant, Sarah Bouteben, Juliette Kaeffer, Raphaëlle Quillet, Pascal Villa, Renaud Wagner, Sandra Lecat, Frédéric Simonin

مصطلحات موضوعية: Biophysics, Cell Biology, Sciences du Vivant [q-bio]/Biochimie, Biologie Moléculaire, Molecular Biology, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a4d470d7b843daa73def884c675ec9
https://linkinghub.elsevier.com/retrieve/pii/S0003269723000271

المؤلفون: Khadija Elhabazi, author¹, Safia Ayachi, author¹, Brigitte Ilien, author¹, Frédéric Simonin, author¹

المصدر: Journal of Visualized Experiments. (89)

الإتاحة: http://www.jove.com/video/51264

المؤلفون: Patrick Gizzi, Brigitte Ilien, Raphaëlle Quillet, Valérie Kugler, Frédéric Simonin, Valérie Simonneaux, Martine Schmitt, Frédéric Bihel, Khadija Elhabazi, Valérie Utard, Jo B. Henningsen, Armand Drieu la Rochelle, Séverine Schneider

المساهمون: Biotechnologie et signalisation cellulaire (BSC), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Institut de recherche de l'Ecole de biotechnologie de Strasbourg (IREBS), Laboratoire d'Innovation Thérapeutique (LIT), Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Institut de Chimie du CNRS (INC), Institut des Neurosciences Cellulaires et Intégratives (INCI), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Plate-forme de chimie biologique intégrative de Strasbourg (PCBiS), Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA), ANR-17-EURE-0022,EURIDOL,Ecole Universitaire de Recherche Interdisciplinaire sur la Douleur(2017), ANR-10-LABX-0034,Medalis,Medalis Drug Discovery Center(2010)

المصدر: Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2021, 64 (11), pp.7555-7564. ⟨10.1021/acs.jmedchem.1c00256⟩

مصطلحات موضوعية: 0303 health sciences, Chemistry, medicine.drug_class, Antagonist, Chronic pain, Neuropeptide, Pharmacology, Receptor antagonist, medicine.disease, 01 natural sciences, 3. Good health, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, Drug Discovery, Hyperalgesia, medicine, Molecular Medicine, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Neuropeptide FF, medicine.symptom, Receptor, Opioid-induced hyperalgesia, ComputingMilieux_MISCELLANEOUS, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc033340f680288639fd0c6e10518c96
https://hal.archives-ouvertes.fr/hal-03363456/document

المؤلفون: Raphaëlle, Quillet, Séverine, Schneider, Valérie, Utard, Armand, Drieu la Rochelle, Khadija, Elhabazi, Jo Beldring, Henningsen, Patrick, Gizzi, Martine, Schmitt, Valérie, Kugler, Valérie, Simonneaux, Brigitte, Ilien, Frédéric, Simonin, Frédéric, Bihel

المصدر: Journal of medicinal chemistry. 64(11)

مصطلحات موضوعية: Male, Receptors, Neuropeptide, Neuropeptides, Dipeptides, Luteinizing Hormone, Analgesics, Opioid, Fentanyl, Mice, Inbred C57BL, Mice, Structure-Activity Relationship, Hyperalgesia, Cricetinae, Receptors, Opioid, Animals, Humans, Protein Isoforms, Female, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::1e529d376378670e47de2cac05128375
https://pubmed.ncbi.nlm.nih.gov/34008968

المؤلفون: Steven Ballet, Jolien De Neve, Frédéric Bihel, Frédéric Simonin, Dirk Tourwé, Thomas M. A. Barlow

المساهمون: Simonin, Frederic, Laboratoire d'Innovation Thérapeutique (LIT), Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Institut de Chimie du CNRS (INC), Biotechnologie et signalisation cellulaire (BSC), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Institut de recherche de l'Ecole de biotechnologie de Strasbourg (IREBS), Chemistry, Faculty of Sciences and Bioengineering Sciences, Vriendenkring VUB, High Resolution NMR Centre, Organic Chemistry, Research Group of Organic Chemistry, Departments of Chemistry and Bioengineering Sciences, Vrije Universiteit Brussel, Brussels, Belgium

المصدر: RSC Medicinal Chemistry
RSC Medicinal Chemistry, 2021, 12 (6), pp.828-870. ⟨10.1039/D1MD00041A⟩
RSC Med Chem
RSC Medicinal Chemistry, Royal Society of Chemistry, 2021

مصطلحات موضوعية: 0301 basic medicine, Moderate to severe, [CHIM.THER] Chemical Sciences/Medicinal Chemistry, NOP, Pharmaceutical Science, Physical dependence, [CHIM.THER]Chemical Sciences/Medicinal Chemistry, Pharmacology, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Drug Discovery, Functional selectivity, medicine, Receptor, ComputingMilieux_MISCELLANEOUS, G protein-coupled receptor, business.industry, Organic Chemistry, [SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences, 3. Good health, Chemistry, 030104 developmental biology, Opioid, [SDV.SP.PHARMA] Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, Molecular Medicine, medicine.symptom, business, 030217 neurology & neurosurgery, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cad0b75b0fb537714b4ed95a2ea83ea0
https://hal-cnrs.archives-ouvertes.fr/hal-03435229

المؤلفون: Manon Gerum, Frédéric Simonin

المساهمون: Biotechnologie et signalisation cellulaire (BSC), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Institut de recherche de l'Ecole de biotechnologie de Strasbourg (IREBS)

المصدر: Pharmacology and Therapeutics
Pharmacology and Therapeutics, Elsevier, In press, ⟨10.1016/j.pharmthera.2021.108032⟩
Pharmacology & Therapeutics
Pharmacology & Therapeutics, 2021

مصطلحات موضوعية: [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, Latent pain sensitization, Opioid, 03 medical and health sciences, 0302 clinical medicine, Intracellular signaling pathways, 030202 anesthesiology, Anti-opioid, Medicine, Animals, Humans, Pharmacology (medical), Clinical significance, Sciences du Vivant [q-bio]/Sciences pharmaceutiques, Sensitization, hyperalgesia, Pharmacology, Spinal cord, business.industry, Chronic pain, medicine.disease, Blockade, Analgesics, Opioid, Disease Models, Animal, medicine.anatomical_structure, Nociception, Hyperalgesia, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, medicine.symptom, business, chronic pain, Neuroscience, 030217 neurology & neurosurgery, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d14e08d85b644295b92fb1b3cbe62e3f
https://hal.archives-ouvertes.fr/hal-03442053/file/islandora_126605.pdf

المؤلفون: Frédéric Simonin, Sandra Lecat, Juliette Kaeffer, Gabrielle Zeder-Lutz

المساهمون: Biotechnologie et signalisation cellulaire (BSC), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Institut de recherche de l'Ecole de biotechnologie de Strasbourg (IREBS)

المصدر: Current Topics in Medicinal Chemistry
Current Topics in Medicinal Chemistry, Bentham Science Publishers, 2021, 21 (3), pp.227-254. ⟨10.2174/1568026620666201202102448⟩

مصطلحات موضوعية: Lung Diseases, Subfamily, neurite outgrowth, Protein family, Vesicular Transport Proteins, Biology, Sciences du Vivant [q-bio]/Biochimie, Biologie Moléculaire, Neoplasms, mitochondria dynamics, Drug Discovery, Animals, Humans, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, signalling, G protein-coupled receptor, Armadillo Domain Proteins, Genetics, Sciences du Vivant [q-bio]/Biologie animale, membrane trafficking, General Medicine, 16. Peace & justice, Hedgehog signaling pathway, α-solenoid scaffolding proteins, Transmembrane domain, Psychotic Disorders, ciliopathies, Chimie/Chimie thérapeutique, ARMCX3, pharmacology, Smoothened, ARMCX1

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8e297d8e649dfa034e1f634253554a2
https://hal.archives-ouvertes.fr/hal-03095663

المؤلفون: José T. Real, Stephan Paschke, Lajos Balogh, Jong-Seok Lim, E. Marion Schneider, Raphaëlle Quillet, Sorim Nam, Safia Ayachi, Frédéric Simonin, Tamás Röszer, Julianna Thuróczy, Grace Ampem, Jin-Chung Chen, Hind Azegrouz, Jacqueline A. Brinkman, Ivan C. Gerling, Ya Tin Lin, Anh Cuong Hoang, Syed F. Hassnain Waqas, Dudley W. Lamming, Juncal Martinez-Ibañez, Christine M. Seroogy

المساهمون: Biotechnologie et signalisation cellulaire (BSC), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Institut de recherche de l'Ecole de biotechnologie de Strasbourg (IREBS)

المصدر: JOURNAL OF CLINICAL INVESTIGATION
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2017, 127 (7), pp.2842-2854. ⟨10.1172/JCI90152⟩

مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, [SDV.BIO]Life Sciences [q-bio]/Biotechnology, Ubiquitin-Protein Ligases, Adipose tissue macrophages, MafB Transcription Factor, Adipose tissue, Mice, Transgenic, Receptors, Cell Surface, Self renewal, Mice, 03 medical and health sciences, Clinical investigation, Internal medicine, medicine, Animals, Neuropeptide FF, Transcription factor, Adaptor Proteins, Signal Transducing, Cell Proliferation, STAT6, 2. Zero hunger, Arginase, biology, business.industry, Chemistry, Macrophages, Proteins, Sciences du Vivant [q-bio]/Biotechnologies, General Medicine, Macrophage Activation, Interleukin-10, Ubiquitin ligase, Cell biology, Endocrinology, 030104 developmental biology, Adipose Tissue, MAFB, biology.protein, Interleukin-4, Corrigendum, business, Oligopeptides, Macrophage proliferation, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3220b01bb94ed57d829585424e149c3
https://doi.org/10.1172/jci90152

المؤلفون: Dirk Tourwé, Ambikaipakan Balasubramaniam, Paul Boon, Jean-Jacques Bourguignon, Jean-Paul Humbert, Martine Schmitt, An De Prins, Jeanelle Portelli, Alfred Meurs, Isabelle Bertin, Frédéric Simonin, Frédéric Bihel, Jessica Coppens, Ilse Julia Smolders, Veronique Maes, Joery De Kock, Ann Massie, Tamara Vanhaecke, Valérie Utard, Ine Buffel, Hassan Hammoud

المساهمون: Laboratoire d'Innovation Thérapeutique (LIT), Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Institut de Chimie du CNRS (INC), Biotechnologie et signalisation cellulaire (BSC), Université de Strasbourg (UNISTRA)-Institut de recherche de l'Ecole de biotechnologie de Strasbourg (IREBS)-Centre National de la Recherche Scientifique (CNRS), Pharmaceutical and Pharmacological Sciences, Neuroprotection & Neuromodulation, Chemistry, Vriendenkring VUB, Organic Chemistry, Experimental Pharmacology, Experimental in vitro toxicology and dermato-cosmetology

المصدر: Neuropharmacology
Neuropharmacology, Elsevier, 2015, 95, pp.415-423. ⟨10.1016/j.neuropharm.2015.04.030⟩

مصطلحات موضوعية: Male, Receptors, Neuropeptide, Agonist, medicine.medical_specialty, [SDV.BIO]Life Sciences [q-bio]/Biotechnology, medicine.drug_class, medicine.medical_treatment, Neuropeptide FF receptor, Adamantane, CHO Cells, Pharmacology, Arginine, Cellular and Molecular Neuroscience, Epilepsy, Cricetulus, Seizures, Internal medicine, Limbic System, medicine, Animals, Humans, Neuropeptide FF, Rats, Wistar, Receptor, Chemistry, Pilocarpine, Dipeptides, Neuropeptide Y receptor, Receptor antagonist, medicine.disease, Receptors, Neuropeptide Y, Disease Models, Animal, HEK293 Cells, Anticonvulsant, Endocrinology, Anticonvulsants

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d46bff75dcb54af8e1ab57527bb3707
https://doi.org/10.1016/j.neuropharm.2015.04.030