يعرض 1 - 10 نتائج من 48 نتيجة بحث عن '"Francis Giraud"', وقت الاستعلام: 1.27s تنقيح النتائج
  1. 1
    دورية أكاديمية
    The Nitro Group Reshapes the Effects of Pyrido[3,4-g]quinazoline Derivatives on DYRK/CLK Activity and RNA Splicing in Glioblastoma Cells

    المؤلفون: Sophia S. Borisevich, Tatiana E. Aksinina, Margarita G. Ilyina, Victoria O. Shender, Ksenia S. Anufrieva, Georgij P. Arapidi, Nadezhda V. Antipova, Fabrice Anizon, Yannick J. Esvan, Francis Giraud, Victor V. Tatarskiy, Pascale Moreau, Mikhail I. Shakhparonov, Marat S. Pavlyukov, Alexander A. Shtil

    المصدر: Cancers, Vol 16, Iss 4, p 834 (2024)

    مصطلحات موضوعية: pyridoquinazolines, DYRK protein kinases, CLK protein kinases, quantum chemical calculations, gene transcription, RNA splicing, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

    وصف الملف: electronic resource

    Relation: https://www.mdpi.com/2072-6694/16/4/834; https://doaj.org/toc/2072-6694

    URL الوصول: https://doaj.org/article/f4b3e28217c945669ca9e886717f9bb2

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  2. 2
    دورية أكاديمية
    Synthesis and Kinase Inhibitory Potencies of Pyrazolo[3,4-g]isoquinolines

    المؤلفون: Mathilde Defois, Chloé Rémondin, Béatrice Josselin, Lionel Nauton, Vincent Théry, Fabrice Anizon, Sandrine Ruchaud, Francis Giraud, Pascale Moreau

    المصدر: Molecules, Vol 27, Iss 17, p 5578 (2022)

    مصطلحات موضوعية: pyrroloisoquinolines, kinase inhibition, Organic chemistry, QD241-441

    وصف الملف: electronic resource

    Relation: https://www.mdpi.com/1420-3049/27/17/5578; https://doaj.org/toc/1420-3049

    URL الوصول: https://doaj.org/article/235ac25b2e844150b7176e85977cbef4

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  3. 3
    دورية أكاديمية
    Recent Advances in Pain Management: Relevant Protein Kinases and Their Inhibitors

    المؤلفون: Francis Giraud, Elisabeth Pereira, Fabrice Anizon, Pascale Moreau

    المصدر: Molecules, Vol 26, Iss 9, p 2696 (2021)

    مصطلحات موضوعية: protein kinases, inhibitors, pain, Organic chemistry, QD241-441

    وصف الملف: electronic resource

    Relation: https://www.mdpi.com/1420-3049/26/9/2696; https://doaj.org/toc/1420-3049

    URL الوصول: https://doaj.org/article/b3f3145437ef407dacfb4b6e8ee3d16b

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  4. 4
    Alternative RNA splicing modulates ribosomal composition and determines the spatial phenotype of glioblastoma cells

    المؤلفون: Tatyana D. Larionova, Soniya Bastola, Tatiana E. Aksinina, Ksenia S. Anufrieva, Jia Wang, Victoria O. Shender, Dmitriy E. Andreev, Tatiana F. Kovalenko, Georgij P. Arapidi, Polina V. Shnaider, Anastasia N. Kazakova, Yaroslav A. Latyshev, Victor V. Tatarskiy, Alexander A. Shtil, Pascale Moreau, Francis Giraud, Chaoxi Li, Yichan Wang, Maria P. Rubtsova, Olga A. Dontsova, Michael Condro, Benjamin M. Ellingson, Mikhail I. Shakhparonov, Harley I. Kornblum, Ichiro Nakano, Marat S. Pavlyukov

    المساهمون: Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry (IBCh RAS), Russian Academy of Sciences [Moscow] (RAS), Institut de Chimie de Clermont-Ferrand (ICCF), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA)-Institut national polytechnique Clermont Auvergne (INP Clermont Auvergne), Université Clermont Auvergne (UCA)-Université Clermont Auvergne (UCA)

    المصدر: Nature Cell Biology
    Nature Cell Biology, 2022, 24 (10), pp.1541-1557. ⟨10.1038/s41556-022-00994-w⟩

    مصطلحات موضوعية: Gene Expression Regulation, Neoplastic, Alternative Splicing, Phenotype, Brain Neoplasms, RNA Splicing, Cell Line, Tumor, [CHIM]Chemical Sciences, Humans, Protein Isoforms, RNA, Messenger, Cell Biology, Glioblastoma, Ribosomes

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d82fabd8f7482a77624e3fd653501960
    https://doi.org/10.1038/s41556-022-00994-w

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  5. 5
    Supplementary Figure S2 from A Kinase Inhibitor with Anti-Pim Kinase Activity is a Potent and Selective Cytotoxic Agent Toward Acute Myeloid Leukemia

    المؤلفون: Lars Herfindal, Fabrice Anizon, Stein Ove Døskeland, Pascale Moreau, Gro Gausdal, Tara Helen Dowling, Francis Giraud, Annette K. Brenner, Øystein Bruserud, Reidun Aesoy, Ronja Bjørnstad

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b063659adab664bfac00b1c6a2c5b44
    https://doi.org/10.1158/1535-7163.22506465.v1

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  6. 6
    Supplementary Table S1 from A Kinase Inhibitor with Anti-Pim Kinase Activity is a Potent and Selective Cytotoxic Agent Toward Acute Myeloid Leukemia

    المؤلفون: Lars Herfindal, Fabrice Anizon, Stein Ove Døskeland, Pascale Moreau, Gro Gausdal, Tara Helen Dowling, Francis Giraud, Annette K. Brenner, Øystein Bruserud, Reidun Aesoy, Ronja Bjørnstad

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e531033ec943bd72887ea43f3ba7441
    https://doi.org/10.1158/1535-7163.22506462.v1

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  7. 7
    Data from A Kinase Inhibitor with Anti-Pim Kinase Activity is a Potent and Selective Cytotoxic Agent Toward Acute Myeloid Leukemia

    المؤلفون: Lars Herfindal, Fabrice Anizon, Stein Ove Døskeland, Pascale Moreau, Gro Gausdal, Tara Helen Dowling, Francis Giraud, Annette K. Brenner, Øystein Bruserud, Reidun Aesoy, Ronja Bjørnstad

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f6bdfd6e8482005500d5231666572b03
    https://doi.org/10.1158/1535-7163.c.6538410.v1

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  8. 8
    Synthesis of new pyrazolo[4,3-a]phenanthridine Pim-1 inhibitors and evaluation of their cytotoxic activity towards the MOLM-13 acute myeloid leukemia cell line

    المؤلفون: Etienne Auvert, Reidun Aesoy, Francis Giraud, Lars Herfindal, Fabrice Anizon, Pascale Moreau

    المساهمون: Institut de Chimie de Clermont-Ferrand (ICCF), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA)-Institut national polytechnique Clermont Auvergne (INP Clermont Auvergne), Université Clermont Auvergne (UCA)-Université Clermont Auvergne (UCA), Department of Clinical Science, University of Bergen

    المصدر: Bioorganic & Medicinal Chemistry Letters
    Bioorganic & Medicinal Chemistry Letters, 2022, 73, pp.128914. ⟨10.1016/j.bmcl.2022.128914⟩

    مصطلحات موضوعية: Pim kinase inhibitors, Acute myeloid leukemia, [CHIM.ORGA]Chemical Sciences/Organic chemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Apoptosis, [SDV.CAN]Life Sciences [q-bio]/Cancer, Antiproliferative activity, Biochemistry, Phenanthridines, Leukemia, Myeloid, Acute, Proto-Oncogene Proteins c-pim-1, Cell Line, Tumor, Drug Discovery, Pyrazolo[4 3-a]phenanthridine, Molecular Medicine, Humans, Molecular Biology, Protein Kinase Inhibitors, Cell Proliferation

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11d843c21b71b10a25bc27e457f8671e
    https://hal.science/hal-03764764

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  9. 9
    Synthesis and biological evaluation of Haspin inhibitors: Kinase inhibitory potency and cellular activity

    المؤلفون: Wael Zeinyeh, Yannick J. Esvan, Béatrice Josselin, Mathilde Defois, Blandine Baratte, Stefan Knapp, Apirat Chaikuad, Fabrice Anizon, Francis Giraud, Sandrine Ruchaud, Pascale Moreau

    المساهمون: Institut de Chimie de Clermont-Ferrand (ICCF), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA)-Institut national polytechnique Clermont Auvergne (INP Clermont Auvergne), Université Clermont Auvergne (UCA)-Université Clermont Auvergne (UCA), Station biologique de Roscoff (SBR), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Fédération de recherche de Roscoff (FR2424), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Goethe-Universität Frankfurt am Main

    المصدر: European Journal of Medicinal Chemistry
    European Journal of Medicinal Chemistry, 2022, 236, pp.114369. ⟨10.1016/j.ejmech.2022.114369⟩

    مصطلحات موضوعية: Pharmacology, kinase inhibition, Structure-Activity Relationship, Haspin, Organic Chemistry, Drug Discovery, Intracellular Signaling Peptides and Proteins, Humans, General Medicine, [CHIM.THER]Chemical Sciences/Medicinal Chemistry, Protein Serine-Threonine Kinases, pyridoquinazolines, Protein Kinase Inhibitors

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a36ce1a31bc5013eb48e29b8a365f5c
    https://pubmed.ncbi.nlm.nih.gov/35447555

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  10. 10
    Recent Advances in Pain Management: Relevant Protein Kinases and Their Inhibitors

    المؤلفون: Elisabeth Pereira, Pascale Moreau, Francis Giraud, Fabrice Anizon

    المساهمون: Institut de Chimie de Clermont-Ferrand (ICCF), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA)-Institut national polytechnique Clermont Auvergne (INP Clermont Auvergne), Université Clermont Auvergne (UCA)-Université Clermont Auvergne (UCA)

    المصدر: Molecules
    Molecules, 2021, 26 (9), pp.2696. ⟨10.3390/molecules26092696⟩
    Molecules, MDPI, 2021, 26 (9), pp.2696. ⟨10.3390/molecules26092696⟩
    Molecules, Vol 26, Iss 2696, p 2696 (2021)

    مصطلحات موضوعية: MAPK/ERK pathway, p38 mitogen-activated protein kinases, Pharmaceutical Science, Review, Biology, Analytical Chemistry, Structure-Activity Relationship, 03 medical and health sciences, QD241-441, 0302 clinical medicine, Cyclin-dependent kinase, Drug Discovery, inhibitors, Animals, Humans, Pain Management, [CHIM]Chemical Sciences, Kinome, ASK1, pain, Physical and Theoretical Chemistry, Protein kinase A, Protein Kinase Inhibitors, 030304 developmental biology, 0303 health sciences, protein kinases, Kinase, Organic Chemistry, Chemistry (miscellaneous), Cancer research, biology.protein, Molecular Medicine, Casein kinase 1, 030217 neurology & neurosurgery

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a1569de3532ceb30c939fa4729c374b
    https://uca.hal.science/hal-03219644/document

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