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1دورية أكاديمية
المؤلفون: John L. Vahle, Joe Dybowski, Michael Graziano, Shigeru Hisada, Jose Lebron, Thomas Nolte, Ronald Steigerwalt, Kenjiro Tsubota, Frank D. Sistare
المصدر: Frontiers in Toxicology, Vol 6 (2024)
مصطلحات موضوعية: carcinogenicity testing, rat carcinogenicity, rasH2-Tg mouse dose selection, regulatory toxicology, carcinogenicity weight-of-evidence criteria, best practice, Toxicology. Poisons, RA1190-1270
وصف الملف: electronic resource
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المؤلفون: Keren J. Carss, Aimee M. Deaton, Alberto Del Rio-Espinola, Dorothée Diogo, Mark Fielden, Diptee A. Kulkarni, Jonathan Moggs, Peter Newham, Matthew R. Nelson, Frank D. Sistare, Lucas D. Ward, Jing Yuan
المصدر: Nature Reviews Drug Discovery. 22:145-162
مصطلحات موضوعية: Pharmacology, Drug Discovery, General Medicine
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3
المؤلفون: J Christopher Corton, Constance A Mitchell, Scott Auerbach, Pierre Bushel, Heidrun Ellinger-Ziegelbauer, Patricia A Escobar, Roland Froetschl, Alison H Harrill, Kamin Johnson, James E Klaunig, Arun R Pandiri, Alexei A Podtelezhnikov, Julia E Rager, Keith Q Tanis, Jan Willem van der Laan, Alisa Vespa, Carole L Yauk, Syril D Pettit, Frank D Sistare
المصدر: Toxicological Sciences. 188:4-16
مصطلحات موضوعية: Carcinogenesis, Carcinogenicity Tests, Neoplasms, Biomarkers, Tumor, Carcinogens, Animals, Rodentia, Genomics, Toxicology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab1ea167ef959d91cb05ee2aeb0e6fc9
https://doi.org/10.1093/toxsci/kfac041 -
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المؤلفون: Katerina, Vlasakova, Jennifer, Bourque, Wendy J, Bailey, Shetal, Patel, Elizabeth G, Besteman, Raymond J, Gonzalez, Frank D, Sistare, Warren E, Glaab
المصدر: Toxicological Sciences. 187:219-233
مصطلحات موضوعية: Inflammation, Tissue Inhibitor of Metalloproteinase-1, Orosomucoid, Acute Kidney Injury, Toxicology, Pregnancy-Associated alpha 2-Macroglobulins, Rats, Lipocalin-2, ROC Curve, Pregnancy, Albumins, Animals, Female, Biomarkers
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b063b32a14b4046a9ff7c68d7d3fd6a5
https://doi.org/10.1093/toxsci/kfac030 -
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المؤلفون: Frank D. Sistare, Takanori Ikeda, Shigeru Hisada, Hisaharu Yamada, Kenji Inoue, Kenjiro Tsubota
المصدر: Journal of Toxicologic Pathology. 35:53-73
مصطلحات موضوعية: Andrology, Rodent, biology, biology.animal, Sensitivity (control systems), Toxicology, Pathology and Forensic Medicine
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9659600d7a670d10a8a26b7394849ef
https://doi.org/10.1293/tox.2021-0031 -
6
المؤلفون: Stephanie Born, Yi-Zhong Gu, Larry Handt, Vasudevan Bakthavatchalu, Katerina Vlasakova, Frank D. Sistare, Guillermo Fernandez, Warren E. Glaab, Roger Smith
المصدر: Toxicologic Pathology. 50:35-46
مصطلحات موضوعية: medicine.medical_specialty, Pathology, Biopsy, Urinary system, Kidney, Toxicology, Pathology and Forensic Medicine, chemistry.chemical_compound, medicine, Animals, Osteopontin, Molecular Biology, Blood urea nitrogen, Creatinine, medicine.diagnostic_test, Clusterin, biology, urogenital system, business.industry, Gene Expression Profiling, Cell Biology, Acute Kidney Injury, Macaca mulatta, medicine.anatomical_structure, chemistry, Tobramycin, biology.protein, Histopathology, business, Biomarkers
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7000c83ea307a501b9d6a6443782431f
https://doi.org/10.1177/01926233211049171 -
7Early-Onset albuminuria and Associated Renal Pathology in Leucine-Rich Repeat Kinase 2 Knockout Rats
المؤلفون: Yi-Zhong Gu, Katerina Vlasakova, Glen Miller, Nicholas T. Gatto, Paul J. Ciaccio, Sabu Kuruvilla, Elizabeth G. Besteman, Roger Smith, Spencer J. Reynolds, Rupesh P. Amin, Warren E. Glaab, Gordon Wollenberg, Jose Lebron, Frank D. Sistare
المصدر: Toxicologic Pathology. :019262332311628
مصطلحات موضوعية: Cell Biology, Toxicology, Molecular Biology, Pathology and Forensic Medicine
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ca81b65118f034c663e621457909c3ff
https://doi.org/10.1177/01926233231162809 -
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المؤلفون: José A. Lebrón, Kaushik Mitra, Keith Q. Tanis, Thomas G. Griffiths, Stephen Pacchione, Matthew Kuhls, Ian Knemeyer, Donald J Marsh, Wen Kang, Frank D. Sistare, Zhibin Wang, Qing Chen, Kimberly B. Bleicher, Ming Su, George M. Laws, Alexei A. Podtelezhnikov
المصدر: Toxicological Sciences. 177:121-139
مصطلحات موضوعية: Male, 0301 basic medicine, Drug, media_common.quotation_subject, Alternatives to animal testing, Pharmacology, Toxicology, 030226 pharmacology & pharmacy, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, Animals, Medicine, Rats, Wistar, media_common, Liver injury, business.industry, Drug discovery, medicine.disease, Rats, 030104 developmental biology, Pharmaceutical Preparations, Toxicity, Chemical and Drug Induced Liver Injury, business, Toxicogenomics, Risk assessment
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b7417a59766a499501f8970dc21422c
https://doi.org/10.1093/toxsci/kfaa094 -
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المؤلفون: Sam V Machotka, Frank D. Sistare, Amy G. Aslamkhan, Alex M Tamburino, Todd Pippert, Raymond Evers, Kaushik Mitra, Keith Q. Tanis, Timothy E. Johnson, Donna Lynch, Wen Kang, Truyen Nguyen, Randy R. Miller, James J Monroe, Tamara D. Cabalu, Alexei A. Podtelezhnikov, Nancy G. B. Agrawal, Jairam Palamanda
المصدر: Toxicological Sciences
مصطلحات موضوعية: Male, 0301 basic medicine, Drug, Pharmaceutical drug, AcademicSubjects/SCI01040, drug safety, NF-E2-Related Factor 2, media_common.quotation_subject, medicine.medical_treatment, Pharmacology, lead optimization, Toxicology, 030226 pharmacology & pharmacy, NRF1, NRF2, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, Drug Development, In vivo, Animals, Medicine, transcriptional biomarkers, Rats, Wistar, Regulatory Science, Risk Assessment, and Decision Making, media_common, Liver injury, bioactivation, drug candidate attrition, Kelch-Like ECH-Associated Protein 1, AcademicSubjects/MED00305, business.industry, medicine.disease, KEAP1, Rats, rat liver, 030104 developmental biology, Pharmaceutical Preparations, Drug development, Biomarker (medicine), Chemical and Drug Induced Liver Injury, business, drug-induced liver injury, chemically reactive metabolites
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2892a55e03df13402f0ef50b67f49d4b
https://doi.org/10.1093/toxsci/kfaa088 -
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المؤلفون: Thomas R. Skopek, Warren E. Glaab, Laura Michna, Carolann Beare, Wendy J. Bailey, Frank D. Sistare, Daniel J. Holder, Nagaraja Muniappa, David Gerhold, Joseph F. Sina, Yudong D He, Jeffrey W. Lawrence, Zoltan Erdos, Pamela Lane, Keith Q. Tanis
المصدر: Toxicological sciences : an official journal of the Society of Toxicology. 181(2)
مصطلحات موضوعية: Gastrointestinal tract, Pathology, medicine.medical_specialty, Kidney, Urinary bladder, Gene Expression Profiling, Skeletal muscle, Toxicology, Risk Assessment, Rats, Tissue Degeneration, Real-time polymerase chain reaction, medicine.anatomical_structure, Liver, Pharmaceutical Preparations, medicine, Biomarker (medicine), Animals, Pancreas, Transcriptome
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d035f511764e56dbc4c0a33dd1ef1df
https://pubmed.ncbi.nlm.nih.gov/33837425