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1دورية أكاديمية
المؤلفون: Aleksandra Wlodek, Steve G. Kendrew, Nigel J. Coates, Adam Hold, Joanna Pogwizd, Steven Rudder, Lesley S. Sheehan, Sarah J. Higginbotham, Anna E. Stanley-Smith, Tony Warneck, Mohammad Nur-E-Alam, Markus Radzom, Christine J. Martin, Lois Overvoorde, Markiyan Samborskyy, Silke Alt, Daniel Heine, Guy T. Carter, Edmund I. Graziani, Frank E. Koehn, Leonard McDonald, Alexander Alanine, Rosa María Rodríguez Sarmiento, Suzan Keen Chao, Hasane Ratni, Lucinda Steward, Isobel H. Norville, Mitali Sarkar-Tyson, Steven J. Moss, Peter F. Leadlay, Barrie Wilkinson, Matthew A. Gregory
المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2041-1723
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2
المؤلفون: Anabella Villalobos, Guoyun Bai, Xinjun Hou, Michael J. Shapiro, Matthew P. Jacobson, Frank E. Koehn, Qin Wang, Simone Sciabola, Gabriela Barreiro
المصدر: Journal of Chemical Information and Modeling. 56:2194-2206
مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, General Chemical Engineering, Molecular Conformation, Library and Information Sciences, Dihedral angle, 010402 general chemistry, Ring (chemistry), 01 natural sciences, Permeability, 03 medical and health sciences, Synthetic biology, Polyketide, chemistry.chemical_compound, Databases, Protein, Biological Products, Natural product, Drug discovery, Computational Biology, Sampling (statistics), General Chemistry, Combinatorial chemistry, 0104 chemical sciences, Computer Science Applications, 030104 developmental biology, chemistry, Polyketides, Target binding
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3
المؤلفون: Edmund I. Graziani, Judy Lucas, L. Nathan Tumey, Frank Loganzo, Li-Ping Chang, Vlad Buklan, T. Eric Ballard, Fengping Li, Brian Rago, Christopher J. O’Donnell, Frank E. Koehn, Christine Hosselet, Jeffrey E. Janso, Anokha S. Ratnayake, Joseph A. Chemler, Xidong Feng, WeiDong Ding, Melissa Wagenaar, Sylvia Musto, Greg L. Steele
المصدر: Bioconjugate chemistry. 30(1)
مصطلحات موضوعية: Immunoconjugates, Biomedical Engineering, Pharmaceutical Science, Bioengineering, 02 engineering and technology, Echinomycin, Conjugated system, 01 natural sciences, chemistry.chemical_compound, Mice, Antineoplastic Agents, Immunological, In vivo, Cell Line, Tumor, Depsipeptides, Animals, Humans, Pharmacology, Depsipeptide, Biological Products, Natural product, 010405 organic chemistry, Organic Chemistry, DNA, Genes, erbB-2, Trastuzumab, 021001 nanoscience & nanotechnology, Combinatorial chemistry, In vitro, Intercalating Agents, 0104 chemical sciences, chemistry, Heterografts, 0210 nano-technology, Linker, Biotechnology, Conjugate, Half-Life
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4
المؤلفون: Frank Loganzo, Frank Barletta, Jesse Alexander Teske, Dangshe Ma, Sylvia Musto, Chakrapani Subramanyam, Hans-Peter Gerber, L. Nathan Tumey, Ken Dirico, Christopher J. O’Donnell, Judy Lucas, Edmund I. Graziani, Puja Sapra, Michael V. Green, Brian Rago, Hadi Falahaptisheh, Haiyin He, Tracey Clark, Frank E. Koehn, Xiaogang Han, Robert Veneziale, Sujiet Puthenveetil
المصدر: Bioconjugate Chemistry. 27:1880-1888
مصطلحات موضوعية: 0301 basic medicine, Spliceosome, Antibody-drug conjugate, Immunoconjugates, DNA damage, Carboxylic Acids, Biomedical Engineering, Pharmaceutical Science, Bioengineering, Maleimides, Mice, 03 medical and health sciences, chemistry.chemical_compound, Cell Line, Tumor, Animals, Humans, Cytotoxic T cell, Tissue Distribution, ATP Binding Cassette Transporter, Subfamily B, Member 1, Cysteine, Pyrans, Pharmacology, Biological Products, Natural product, biology, Chemistry, Lysine, Organic Chemistry, Combinatorial chemistry, Cell biology, Cell Transformation, Neoplastic, 030104 developmental biology, RNA splicing, biology.protein, Antibody, Biotechnology, Conjugate
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5
المؤلفون: Christopher J. Schulze, Roger G. Linington, Teresa Szal, Anabella Villalobos, Frank E. Koehn, Walter M. Bray, My-Hanh Lam, Frank Loganzo
المصدر: Journal of Natural Products. 77:2570-2574
مصطلحات موضوعية: Pharmacology, Molecular Structure, Nitrile, Stereochemistry, Metabolite, Organic Chemistry, Pharmaceutical Science, Biological activity, Biology, Analytical Chemistry, Amino Acyl-tRNA Synthetases, chemistry.chemical_compound, Polyketide, Complementary and alternative medicine, chemistry, Biosynthesis, Biochemistry, Nitriles, Drug Discovery, Transfer RNA, Threonine-tRNA Ligase, Molecular Medicine, Moiety, Fatty Alcohols, Mitosis
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6
المؤلفون: Gerhard Schlingman, Scott Luckman, Leonard A, McDonald, Frank E. Koehn
المصدر: Records of Natural Products, Vol 5, Iss 4, Pp 252-260 (2011)
مصطلحات موضوعية: lcsh:Chemistry, lcsh:QD241-441, Nodulisporium hinnuleum, lcsh:QD1-999, lcsh:Organic chemistry, binaphthyl, lcsh:Botany, oxygen reactive compounds, fungal metabolite, lcsh:QK1-989
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7
المؤلفون: Guy T. Carter, Valerie S. Bernan, Frank E. Koehn
المصدر: Burger's Medicinal Chemistry and Drug Discovery
مصطلحات موضوعية: Polyketide, Microbial genomics, Lead (geology), business.industry, Metagenomics, Chemical diversity, Phenotypic screening, The Renaissance, Computational biology, Biology, business, Natural (archaeology), Biotechnology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::29a8fa592ab30300b210debba69d1f24
https://doi.org/10.1002/0471266949.bmc116 -
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المؤلفون: Frank E. Koehn
المصدر: Journal of Medicinal Chemistry. 51:2613-2617
مصطلحات موضوعية: Biological Products, Natural product, Natural compound, Glycopeptides, Drug Resistance, Microbial, Stereoisomerism, Computational biology, Gram-Positive Bacteria, Combinatorial chemistry, Anti-Bacterial Agents, Structure-Activity Relationship, chemistry.chemical_compound, Mannopeptimycin, chemistry, Drug Discovery, Molecular Medicine, Anti-Infective Agents, Antibacterial agent
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9
المؤلفون: Andrew R. Wood, Guy T. Carter, Edmund I. Graziani, Menelas N. Pangalos, Kevin Pong, Frank E. Koehn, Benfang Ruan, Ronald L. Magolda, Magid Abou-Gharbia, Robert A. Crozier, Flora Jow, Frann Bennett, Danni Liu, Mark R. Bowlby, Peter H. Reinhart, Xidong Feng, Mary Lynn T. Mercado, Leonard A. McDonald, Shi Liang, Yi Chen, Jerauld S. Skotnicki, Margaret M. Zaleska, David von Schack
المصدر: Proceedings of the National Academy of Sciences. 105:33-38
مصطلحات موضوعية: Patch-Clamp Techniques, Neurite, Pharmacology, Ligands, Tacrolimus Binding Proteins, Neuroblastoma, Neurites, Animals, Humans, Patch clamp, Immunophilins, Binding selectivity, Neurons, Sirolimus, Multidisciplinary, biology, Voltage-dependent calcium channel, FKBP52, Rats, Electrophysiology, Stroke, FKBP, Models, Chemical, Physical Sciences, biology.protein, Calcium, Calcium Channels, Immunosuppressive Agents, Protein Binding, Neurotrophin
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c60bb03f86803494ea3efa91d69a376
https://doi.org/10.1073/pnas.0710424105 -
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المؤلفون: Guy T. Carter, Tohru Taniguchi, Nina Berova, Hui Y. Yang, Ramunas Bigelis, Haiyin He, Gerhard Schlingmann, Frank E. Koehn
المصدر: Journal of Natural Products. 70:1180-1187
مصطلحات موضوعية: Circular dichroism, Stereochemistry, Metabolite, Molecular Conformation, Ab initio, Pharmaceutical Science, Crystallography, X-Ray, Citric Acid, Analytical Chemistry, chemistry.chemical_compound, Drug Discovery, Molecule, Pyrroles, Secondary metabolism, Pharmacology, Molecular Structure, biology, Organic Chemistry, Aspergillus niger, Absolute configuration, Stereoisomerism, biology.organism_classification, Complementary and alternative medicine, chemistry, Pyrones, Molecular Medicine, Density functional theory