المؤلفون: Roche SM; St James's Hospital, National Tuberculosis Centre, Department of Respiratory Medicine,, Dublin , Ireland; suzanneroche1@gmail.com., Ottewill C; St James's Hospital, National Tuberculosis Centre, Department of Respiratory Medicine,, Dublin, Ireland., Mulpeter R; St James's Hospital, National Tuberculosis Centre, Department of Respiratory Medicine,, Dublin, Ireland., Brown K; St James's Hospital, National Tuberculosis Centre, Department of Respiratory Medicine,, Dublin, Ireland., Grant C; St James's Hospital, National Tuberculosis Centre, Department of Respiratory Medicine,, Dublin, Ireland., Fraughen DD; St James's Hospital, National Tuberculosis Centre, Department of Respiratory Medicine,, Dublin, Ireland., Dolan L; St James's Hospital, National Tuberculosis Centre, Department of Respiratory Medicine,, Dublin, Ireland., Gleeson LE; St James's Hospital, National Tuberculosis Centre, Department of Respiratory Medicine,, Dublin, Ireland.; Trinity College Dublin, Department of Medicine, Dublin, Ireland., McLaughlin AM; St James's Hospital, National Tuberculosis Centre, Department of Respiratory Medicine,, Dublin, Ireland., Keane J; St James's Hospital, National Tuberculosis Centre, Department of Respiratory Medicine,, Dublin, Ireland.; Trinity College Dublin, Department of Medicine, Dublin, Ireland.

المصدر: American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2024 Aug 12. Date of Electronic Publication: 2024 Aug 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Thoracic Society Country of Publication: United States NLM ID: 9421642 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-4970 (Electronic) Linking ISSN: 1073449X NLM ISO Abbreviation: Am J Respir Crit Care Med Subsets: MEDLINE

المؤلفون: Fraughen DD; Department of Medicine, Irish Center for Genetic Lung Disease, Royal College of Surgeons in Ireland, Dublin, Ireland; and., Ghosh AJ; Division of Pulmonary, Critical Care, and Sleep Medicine, SUNY Upstate University Hospital, Syracuse, New York., Carroll TP; Department of Medicine, Irish Center for Genetic Lung Disease, Royal College of Surgeons in Ireland, Dublin, Ireland; and., McElvaney NG; Department of Medicine, Irish Center for Genetic Lung Disease, Royal College of Surgeons in Ireland, Dublin, Ireland; and.

المصدر: American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2024 Apr 15; Vol. 209 (8), pp. 1034-1035.

نوع المنشور: Letter

بيانات الدورية: Publisher: American Thoracic Society Country of Publication: United States NLM ID: 9421642 Publication Model: Print Cited Medium: Internet ISSN: 1535-4970 (Electronic) Linking ISSN: 1073449X NLM ISO Abbreviation: Am J Respir Crit Care Med Subsets: MEDLINE

مواضيع طبية MeSH: alpha 1-Antitrypsin*/therapeutic use, Humans ; Spirometry

المؤلفون: Fromme M; Medical Clinic III, Gastroenterology, Metabolic Diseases and Intensive Care, University Hospital RWTH Aachen, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Aachen, Germany., Hamesch K; Medical Clinic III, Gastroenterology, Metabolic Diseases and Intensive Care, University Hospital RWTH Aachen, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Aachen, Germany., Schneider CV; Medical Clinic III, Gastroenterology, Metabolic Diseases and Intensive Care, University Hospital RWTH Aachen, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Aachen, Germany., Mandorfer M; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University Vienna, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Vienna, Austria., Pons M; Liver Unit, Hospital Universitari Vall d'Hebron, Vall d'Hebron Institute of Research, Vall d'Hebron Barcelona Hospital Campus, Universitat Autonoma de Barcelona, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain., Thorhauge KH; Department of Gastroenterology and Hepatology, Odense University Hospital, Odense C, Denmark; Faculty of Health Sciences, Department of Clinical Research, University of Southern Denmark, Odense C, Denmark., Pereira V; Department of Gastroenterology, Centro Hospitalar do Funchal, Madeira, Portugal., Sperl J; Department of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Prague, Czech Republic., Frankova S; Department of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Prague, Czech Republic., Reichert MC; Department of Medicine II, Saarland University Medical Center, Saarland University, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Homburg, Germany., Benini F; Gastroenterology Unit, Department of Medicine, Spedali Civili and University, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Brescia, Italy., Burbaum B; Medical Clinic III, Gastroenterology, Metabolic Diseases and Intensive Care, University Hospital RWTH Aachen, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Aachen, Germany., Kleinjans M; Medical Clinic III, Gastroenterology, Metabolic Diseases and Intensive Care, University Hospital RWTH Aachen, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Aachen, Germany., Amzou S; Medical Clinic III, Gastroenterology, Metabolic Diseases and Intensive Care, University Hospital RWTH Aachen, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Aachen, Germany., Rademacher L; Medical Clinic III, Gastroenterology, Metabolic Diseases and Intensive Care, University Hospital RWTH Aachen, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Aachen, Germany., Bewersdorf L; Medical Clinic III, Gastroenterology, Metabolic Diseases and Intensive Care, University Hospital RWTH Aachen, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Aachen, Germany., Verbeek J; Department of Gastroenterology and Hepatology, KU Leuven University Hospitals, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Leuven, Belgium., Nevens F; Department of Gastroenterology and Hepatology, KU Leuven University Hospitals, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Leuven, Belgium., Genesca J; Liver Unit, Hospital Universitari Vall d'Hebron, Vall d'Hebron Institute of Research, Vall d'Hebron Barcelona Hospital Campus, Universitat Autonoma de Barcelona, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain., Miravitlles M; Pneumology Department, Hospital Universitari Vall d'Hebron, Vall d'Hebron Institut de Recerca, Vall d'Hebron Barcelona Hospital Campus, CIBER de Enfermedades Respiratorias, Barcelona, Spain., Nuñez A; Pneumology Department, Hospital Universitari Vall d'Hebron, Vall d'Hebron Institut de Recerca, Vall d'Hebron Barcelona Hospital Campus, CIBER de Enfermedades Respiratorias, Barcelona, Spain., Schaefer B; Department of Internal Medicine I, Medical University Innsbruck, Innsbruck, Austria., Zoller H; Department of Internal Medicine I, Medical University Innsbruck, Innsbruck, Austria., Janciauskiene S; Clinic for Pneumology, Medical University Hannover, Hannover, Germany., Waern J; Gastroenterology and Hepatology Unit, Department of Medicine, Sahlgrenska University Hospital, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Gothenburg, Sweden., Oliveira A; Department of Gastroenterology, Centro Hospitalar do Funchal, Madeira, Portugal., Maia L; Centro Hospitalar Universitário do Porto, Porto, Portugal., Simões C; Hospital Santa Maria, Lisboa, Portugal., Mahadeva R; Department of Respiratory Medicine, Cambridge University Hospitals, Cambridge, United Kingdom., Fraughen DD; Irish Centre for Genetic Lung Disease, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin, Ireland., Trauner M; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University Vienna, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Vienna, Austria., Krag A; Department of Gastroenterology and Hepatology, Odense University Hospital, Odense C, Denmark; Faculty of Health Sciences, Department of Clinical Research, University of Southern Denmark, Odense C, Denmark., Lammert F; Department of Medicine II, Saarland University Medical Center, Saarland University, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Homburg, Germany; Hannover Medical School, Hannover, Germany., Bals R; Department of Medicine V, Saarland University Medical Center, Saarland University, Homburg, Germany., Gaisa NT; Institute of Pathology, University Hospital RWTH Aachen, Aachen, Germany., Aigner E; First Department of Medicine, Paracelsus Medical University, Salzburg, Austria., Griffiths WJ; Department of Hepatology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom., Denk H; Institute of Pathology, Medical University of Graz, Graz, Austria., Teumer A; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., McElvaney NG; Irish Centre for Genetic Lung Disease, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin, Ireland., Turner AM; Institute of Applied Health Research, University of Birmingham, Birmingham, United Kingdom., Trautwein C; Medical Clinic III, Gastroenterology, Metabolic Diseases and Intensive Care, University Hospital RWTH Aachen, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Aachen, Germany., Strnad P; Medical Clinic III, Gastroenterology, Metabolic Diseases and Intensive Care, University Hospital RWTH Aachen, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE LIVER), Aachen, Germany. Electronic address: pstrnad@ukaachen.de.

المصدر: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association [Clin Gastroenterol Hepatol] 2024 Feb; Vol. 22 (2), pp. 283-294.e5. Date of Electronic Publication: 2023 Sep 15.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: W.B. Saunders for the American Gastroenterological Association Country of Publication: United States NLM ID: 101160775 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1542-7714 (Electronic) Linking ISSN: 15423565 NLM ISO Abbreviation: Clin Gastroenterol Hepatol Subsets: MEDLINE

مواضيع طبية MeSH: alpha 1-Antitrypsin Deficiency*/complications , alpha 1-Antitrypsin Deficiency*/drug therapy, Adult ; Humans ; Genotype ; Liver Cirrhosis/etiology ; Phenotype

المؤلفون: McElvaney OJ; Department of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.; National Centre for Alpha-1 Antitrypsin Deficiency, Beaumont Hospital, Dublin, Ireland.; Seattle Children's Research Institute, Seattle, Washington, United States.; Department of Medicine, University of Washington, Seattle, Washington, United States., Cleary B; Department of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland., Fraughen DD; Department of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.; National Centre for Alpha-1 Antitrypsin Deficiency, Beaumont Hospital, Dublin, Ireland., Kelly G; Alpha-1 Foundation of Ireland, Dublin, Ireland., McElvaney OF; Department of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland., Murphy MP; Department of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland., Branagan P; Department of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.; National Centre for Alpha-1 Antitrypsin Deficiency, Beaumont Hospital, Dublin, Ireland., Gunaratnam C; Department of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.; National Centre for Alpha-1 Antitrypsin Deficiency, Beaumont Hospital, Dublin, Ireland., Carroll TP; Department of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.; Alpha-1 Foundation of Ireland, Dublin, Ireland., Goss CH; Seattle Children's Research Institute, Seattle, Washington, United States.; Department of Medicine, University of Washington, Seattle, Washington, United States.; Department of Pediatrics, University of Washington, Seattle, Washington, United States., McElvaney NG; Department of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.; National Centre for Alpha-1 Antitrypsin Deficiency, Beaumont Hospital, Dublin, Ireland.

المصدر: Chronic obstructive pulmonary diseases (Miami, Fla.) [Chronic Obstr Pulm Dis] 2024 Jan 25; Vol. 11 (1), pp. 3-12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: COPD Foundation Country of Publication: United States NLM ID: 101635411 Publication Model: Print Cited Medium: Print ISSN: 2372-952X (Print) Linking ISSN: 2372952X NLM ISO Abbreviation: Chronic Obstr Pulm Dis Subsets: PubMed not MEDLINE

المؤلفون: Fraughen DD; Department of Medicine, Irish Center for Genetic Lung Disease, Royal College of Surgeons in Ireland, Dublin, Ireland., Ghosh AJ; Division of Pulmonary, Critical Care, and Sleep Medicine, SUNY Upstate University Hospital, Syracuse, New York., Hobbs BD; Channing Division of Network Medicine and Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Massachusetts., Funk GC; Karl Landsteiner Institute for Lung Research and Pulmonary Oncology and Department of Medicine II with Pneumology, Klinik Ottakring, Vienna, Austria., Meischl T; Karl Landsteiner Institute for Lung Research and Pulmonary Oncology and Department of Medicine II with Pneumology, Klinik Ottakring, Vienna, Austria.; Division of Gastroenterology and Hepatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria., Clarenbach CF; Department of Pneumology, University Hospital Zurich, Zurich, Switzerland., Sievi NA; Department of Pneumology, University Hospital Zurich, Zurich, Switzerland., Schmid-Scherzer K; Karl Landsteiner Institute for Lung Research and Pulmonary Oncology and Department of Medicine II with Pneumology, Klinik Ottakring, Vienna, Austria., McElvaney OJ; Department of Medicine, Irish Center for Genetic Lung Disease, Royal College of Surgeons in Ireland, Dublin, Ireland.; Division of Pulmonary, Critical Care and Sleep Medicine, University of Washington, Seattle, Washington., Murphy MP; Department of Medicine, Irish Center for Genetic Lung Disease, Royal College of Surgeons in Ireland, Dublin, Ireland., Roche AD; Department of Medicine, Irish Center for Genetic Lung Disease, Royal College of Surgeons in Ireland, Dublin, Ireland., Clarke L; Department of Respiratory Physiology, Beaumont Hospital, Dublin, Ireland; and., Strand M; Division of Biostatistics and Bioinformatics, National Jewish Health, Denver, Colorado., Vafai-Tabrizi F; Karl Landsteiner Institute for Lung Research and Pulmonary Oncology and Department of Medicine II with Pneumology, Klinik Ottakring, Vienna, Austria., Kelly G; Department of Medicine, Irish Center for Genetic Lung Disease, Royal College of Surgeons in Ireland, Dublin, Ireland., Gunaratnam C; Department of Respiratory Physiology, Beaumont Hospital, Dublin, Ireland; and., Carroll TP; Department of Medicine, Irish Center for Genetic Lung Disease, Royal College of Surgeons in Ireland, Dublin, Ireland., McElvaney NG; Department of Medicine, Irish Center for Genetic Lung Disease, Royal College of Surgeons in Ireland, Dublin, Ireland.

المصدر: American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2023 Nov 01; Vol. 208 (9), pp. 964-974.

نوع المنشور: Observational Study; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Thoracic Society Country of Publication: United States NLM ID: 9421642 Publication Model: Print Cited Medium: Internet ISSN: 1535-4970 (Electronic) Linking ISSN: 1073449X NLM ISO Abbreviation: Am J Respir Crit Care Med Subsets: MEDLINE

مواضيع طبية MeSH: alpha 1-Antitrypsin Deficiency*/complications , alpha 1-Antitrypsin Deficiency*/diagnosis , alpha 1-Antitrypsin Deficiency*/drug therapy , Pulmonary Disease, Chronic Obstructive*, Adult ; Humans ; Middle Aged ; Young Adult ; alpha 1-Antitrypsin/therapeutic use ; alpha 1-Antitrypsin/genetics ; Lung ; Phenotype ; Registries

المؤلفون: Roche SM; Department of Medicine, Irish Centre for Genetic Lung Disease, Royal College of Surgeons in Ireland, Dublin, Ireland; National Centre for Expertise in AATD, Beaumont Hospital, Dublin, Ireland. Electronic address: SuzanneRoche@RCSI.com., Carroll TP; Department of Medicine, Irish Centre for Genetic Lung Disease, Royal College of Surgeons in Ireland, Dublin, Ireland; National Centre for Expertise in AATD, Beaumont Hospital, Dublin, Ireland., Fraughen DD; Department of Medicine, Irish Centre for Genetic Lung Disease, Royal College of Surgeons in Ireland, Dublin, Ireland; National Centre for Expertise in AATD, Beaumont Hospital, Dublin, Ireland., McElvaney NG; Department of Medicine, Irish Centre for Genetic Lung Disease, Royal College of Surgeons in Ireland, Dublin, Ireland; National Centre for Expertise in AATD, Beaumont Hospital, Dublin, Ireland.

المصدر: Chest [Chest] 2023 Apr; Vol. 163 (4), pp. e197.

نوع المنشور: Letter; Comment

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0231335 Publication Model: Print Cited Medium: Internet ISSN: 1931-3543 (Electronic) Linking ISSN: 00123692 NLM ISO Abbreviation: Chest Subsets: MEDLINE

مواضيع طبية MeSH: Smoking Cessation* , alpha 1-Antitrypsin Deficiency*/diagnosis , Pulmonary Disease, Chronic Obstructive*/diagnosis , Pulmonary Disease, Chronic Obstructive*/epidemiology, Humans ; alpha 1-Antitrypsin

المؤلفون: McElvaney OF; Irish Centre for Genetic Lung Disease, Royal College of Surgeons in Ireland, Dublin, Ireland.; Department of Medicine, Beaumont Hospital, Dublin, Ireland., Fraughen DD; Irish Centre for Genetic Lung Disease, Royal College of Surgeons in Ireland, Dublin, Ireland.; Department of Medicine, Beaumont Hospital, Dublin, Ireland., McElvaney OJ; Irish Centre for Genetic Lung Disease, Royal College of Surgeons in Ireland, Dublin, Ireland.; Department of Medicine, Beaumont Hospital, Dublin, Ireland., Carroll TP; Irish Centre for Genetic Lung Disease, Royal College of Surgeons in Ireland, Dublin, Ireland.; Department of Medicine, Beaumont Hospital, Dublin, Ireland.; Alpha-1 Foundation Ireland, Royal College of Surgeons in Ireland, Dublin, Ireland., McElvaney NG; Irish Centre for Genetic Lung Disease, Royal College of Surgeons in Ireland, Dublin, Ireland.; Department of Medicine, Beaumont Hospital, Dublin, Ireland.

المصدر: Expert review of respiratory medicine [Expert Rev Respir Med] 2023 Mar; Vol. 17 (3), pp. 191-202. Date of Electronic Publication: 2023 Mar 15.

نوع المنشور: Review; Journal Article

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101278196 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1747-6356 (Electronic) Linking ISSN: 17476348 NLM ISO Abbreviation: Expert Rev Respir Med Subsets: MEDLINE

مواضيع طبية MeSH: alpha 1-Antitrypsin*/genetics , alpha 1-Antitrypsin*/therapeutic use , alpha 1-Antitrypsin Deficiency*/diagnosis , alpha 1-Antitrypsin Deficiency*/genetics , alpha 1-Antitrypsin Deficiency*/therapy, Humans ; Lung

المؤلفون: McElvaney OJ; Department of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.; Beaumont Hospital, Dublin, Ireland.; Alpha-1 Foundation of Ireland, Dublin, Ireland., Cleary B; Beaumont Hospital, Dublin, Ireland., Fraughen DD; Department of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.; Beaumont Hospital, Dublin, Ireland.; Alpha-1 Foundation of Ireland, Dublin, Ireland., Kelly G; Alpha-1 Foundation of Ireland, Dublin, Ireland., Murphy MP; Department of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland., McElvaney OF; Department of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.; Beaumont Hospital, Dublin, Ireland., Branagan P; Department of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.; Beaumont Hospital, Dublin, Ireland., Gunaratnam C; Department of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.; Beaumont Hospital, Dublin, Ireland., Carroll TP; Department of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.; Alpha-1 Foundation of Ireland, Dublin, Ireland., McElvaney NG; Department of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.; Beaumont Hospital, Dublin, Ireland.; Alpha-1 Foundation of Ireland, Dublin, Ireland.

المصدر: Chronic obstructive pulmonary diseases (Miami, Fla.) [Chronic Obstr Pulm Dis] 2022 Apr 29; Vol. 9 (2), pp. 266-273.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: COPD Foundation Country of Publication: United States NLM ID: 101635411 Publication Model: Print Cited Medium: Print ISSN: 2372-952X (Print) Linking ISSN: 2372952X NLM ISO Abbreviation: Chronic Obstr Pulm Dis Subsets: PubMed not MEDLINE

المؤلفون: McElvaney OJ; Department of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.; Beaumont Hospital, Dublin, Ireland., McEvoy NL; Department of Anaesthesia and Critical Care, Royal College of Surgeons in Ireland, Dublin, Ireland., Boland F; Data Science Centre, Division of Biostatistics and Population Health Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland., McElvaney OF; Department of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.; Beaumont Hospital, Dublin, Ireland., Hogan G; Department of Anaesthesia and Critical Care, Royal College of Surgeons in Ireland, Dublin, Ireland., Donnelly K; Beaumont Hospital, Dublin, Ireland., Friel O; Beaumont Hospital, Dublin, Ireland., Browne E; Beaumont Hospital, Dublin, Ireland., Fraughen DD; Department of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.; Beaumont Hospital, Dublin, Ireland., Murphy MP; Department of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland., Clarke J; Beaumont Hospital, Dublin, Ireland.; Department of Anaesthesia and Critical Care, Royal College of Surgeons in Ireland, Dublin, Ireland., Choileáin ON; Beaumont Hospital, Dublin, Ireland., O'Connor E; Beaumont Hospital, Dublin, Ireland., McGuinness R; Beaumont Hospital, Dublin, Ireland., Boylan M; Beaumont Hospital, Dublin, Ireland., Kelly A; Beaumont Hospital, Dublin, Ireland., Hayden JC; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland., Collins AM; RCSI Education and Research Centre, Beaumont Hospital, Dublin, Ireland., Cullen A; RCSI Education and Research Centre, Beaumont Hospital, Dublin, Ireland., Hyland D; RCSI Education and Research Centre, Beaumont Hospital, Dublin, Ireland., Carroll TP; Department of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland., Geoghegan P; Beaumont Hospital, Dublin, Ireland., Laffey JG; Department of Anaesthesia, Galway University Hospitals, SAOLTA University Health Group, Galway, Ireland., Hennessy M; Department of Critical Care Medicine, St. James' Hospital, Dublin, Ireland., Martin-Loeches I; Department of Critical Care Medicine, St. James' Hospital, Dublin, Ireland., McElvaney NG; Department of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.; Beaumont Hospital, Dublin, Ireland., Curley GF; Beaumont Hospital, Dublin, Ireland.; Department of Anaesthesia and Critical Care, Royal College of Surgeons in Ireland, Dublin, Ireland.

المصدر: Med (New York, N.Y.) [Med] 2022 Apr 08; Vol. 3 (4), pp. 233-248.e6. Date of Electronic Publication: 2022 Mar 11.

نوع المنشور: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101769215 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-6340 (Electronic) Linking ISSN: 26666340 NLM ISO Abbreviation: Med

مواضيع طبية MeSH: COVID-19*/complications , Respiratory Distress Syndrome*/drug therapy , alpha 1-Antitrypsin Deficiency*/drug therapy, Humans ; Interleukin-10/therapeutic use ; Interleukin-6/therapeutic use ; Interleukin-8/therapeutic use ; alpha 1-Antitrypsin/therapeutic use