المؤلفون: Viana LPS; Departamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., Naves GM; Departamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., Medeiros IG; Departamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., Guimarães AS; Instituto de Química e Biotecnologia, Universidade Federal de Alagoas, Maceió, AL, Brazil., Sousa ES; Instituto de Química e Biotecnologia, Universidade Federal de Alagoas, Maceió, AL, Brazil., Santos JCC; Instituto de Química e Biotecnologia, Universidade Federal de Alagoas, Maceió, AL, Brazil., Freire NML; Instituto de Química e Biotecnologia, Universidade Federal de Alagoas, Maceió, AL, Brazil., de Aquino TM; Instituto de Química e Biotecnologia, Universidade Federal de Alagoas, Maceió, AL, Brazil., Modolo LV; Departamento de Botânica, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., de Fátima Â; Departamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., da Silva CM; Departamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil. Electronic address: cleitonms@ufmg.br.

المصدر: Bioorganic chemistry [Bioorg Chem] 2024 May; Vol. 146, pp. 107247. Date of Electronic Publication: 2024 Mar 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

مواضيع طبية MeSH: Hydroxamic Acids*/chemistry , Urease*, Allosteric Site ; Catalytic Domain ; Enzyme Inhibitors/chemistry ; Kinetics ; Molecular Docking Simulation ; Molecular Structure ; Structure-Activity Relationship ; Cinnamates/chemistry

المؤلفون: Monteiro KLC; Research Group on Therapeutic Strategies - GPET, Laboratory of Synthesis and Research in Medicinal Chemistry - LSPMED, Institute of Chemistry and Biotechnology, Federal University of Alagoas, Lourival Melo Mota Avenue, 57072-970, Maceió, Alagoas, Brazil., Dos Santos Alcântara MG; Research Group on Therapeutic Strategies - GPET, Laboratory of Synthesis and Research in Medicinal Chemistry - LSPMED, Institute of Chemistry and Biotechnology, Federal University of Alagoas, Lourival Melo Mota Avenue, 57072-970, Maceió, Alagoas, Brazil., Freire NML; Research Group on Therapeutic Strategies - GPET, Laboratory of Synthesis and Research in Medicinal Chemistry - LSPMED, Institute of Chemistry and Biotechnology, Federal University of Alagoas, Lourival Melo Mota Avenue, 57072-970, Maceió, Alagoas, Brazil., Brandão EM; Research Group on Therapeutic Strategies - GPET, Laboratory of Synthesis and Research in Medicinal Chemistry - LSPMED, Institute of Chemistry and Biotechnology, Federal University of Alagoas, Lourival Melo Mota Avenue, 57072-970, Maceió, Alagoas, Brazil., do Nascimento VL; Research Group on Therapeutic Strategies - GPET, Laboratory of Synthesis and Research in Medicinal Chemistry - LSPMED, Institute of Chemistry and Biotechnology, Federal University of Alagoas, Lourival Melo Mota Avenue, 57072-970, Maceió, Alagoas, Brazil., Dos Santos Viana LM; Research Group on Therapeutic Strategies - GPET, Laboratory of Synthesis and Research in Medicinal Chemistry - LSPMED, Institute of Chemistry and Biotechnology, Federal University of Alagoas, Lourival Melo Mota Avenue, 57072-970, Maceió, Alagoas, Brazil., de Aquino TM; Research Group on Therapeutic Strategies - GPET, Laboratory of Synthesis and Research in Medicinal Chemistry - LSPMED, Institute of Chemistry and Biotechnology, Federal University of Alagoas, Lourival Melo Mota Avenue, 57072-970, Maceió, Alagoas, Brazil., da Silva-Júnior EF; Institute of Chemistry and Biotechnology, Federal University of Alagoas, Lourival Melo Mota Avenue, 57072-970, Maceió, Alagoas, Brazil.

المصدر: Current Alzheimer research [Curr Alzheimer Res] 2023; Vol. 20 (3), pp. 131-148.

نوع المنشور: Review; Journal Article

بيانات الدورية: Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 101208441 Publication Model: Print Cited Medium: Internet ISSN: 1875-5828 (Electronic) Linking ISSN: 15672050 NLM ISO Abbreviation: Curr Alzheimer Res Subsets: MEDLINE

مواضيع طبية MeSH: Amyloid Precursor Protein Secretases*/metabolism , Alzheimer Disease*/drug therapy , Alzheimer Disease*/metabolism, Humans ; Amyloid beta-Protein Precursor/metabolism ; Aspartic Acid Endopeptidases/metabolism ; Amyloid beta-Peptides/metabolism ; Enzyme Inhibitors/pharmacology ; Enzyme Inhibitors/therapeutic use