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المؤلفون: Barros ALAN; Núcleo de Pesquisa em Morfologia e Imunologia Aplicada, NuPMIA, Faculdade de Medicina, Universidade de Brasília, UnB, Brasília 70910-900, DF, Brazil.; Programa de Pós-graduação em Medicina Tropical, PGMT, Faculdade de Medicina, Universidade de Brasília, UnB, Brasília 70910-900, DF, Brazil., Silva VC; Laboratório de Vigilância Genômica e Biologia Molecular-Fundação Oswaldo Cruz Piauí, Teresina 64001-350, PI, Brazil., Ribeiro-Junior AF; Núcleo de Pesquisa em Morfologia e Imunologia Aplicada, NuPMIA, Faculdade de Medicina, Universidade de Brasília, UnB, Brasília 70910-900, DF, Brazil., Cardoso MG; Núcleo de Pesquisa em Morfologia e Imunologia Aplicada, NuPMIA, Faculdade de Medicina, Universidade de Brasília, UnB, Brasília 70910-900, DF, Brazil.; imed.ULisboa-Research Institute for Medicines, Faculty of Pharmacy, University of Lisbon, 1649-003 Lisbon, Portugal., Costa SR; Instituto de Química, IQ, Universidade de Brasília, UnB, Brasília 70910-900, DF, Brazil., Moraes CB; Department of Pharmaceutical Sciences, Federal University of São Paulo, Diadema 09913-030, SP, Brazil., Barbosa CG; Department of Microbiology, Institute of Biomedical Sciences, University of Sao Paulo, São Paulo 05508-000, SP, Brazil., Coleone AP; Programa de Pós-Graduação em Ciência e Tecnologia de Materiais (POSMAT), School of Sciences, São Paulo State University (UNESP), Bauru 17033-360, SP, Brazil., Simões RP; School of Agriculture, Department of Bioprocess and Biotechnology, São Paulo State University (UNESP), Botucatu 18618-689, SP, Brazil., Cabral WF; Núcleo de Pesquisa em Morfologia e Imunologia Aplicada, NuPMIA, Faculdade de Medicina, Universidade de Brasília, UnB, Brasília 70910-900, DF, Brazil., Falcão RM; Bioinformatics Postgraduate Program, Metrópole Digital Institute, Federal University of Rio Grande do Norte, Natal 59078-900, RN, Brazil., Vasconcelos AG; Núcleo de Pesquisa em Morfologia e Imunologia Aplicada, NuPMIA, Faculdade de Medicina, Universidade de Brasília, UnB, Brasília 70910-900, DF, Brazil.; People&Science Pesquisa Desenvolvimento e Inovação LTDA, Centro de Desenvolvimento Tecnológico (CDT), Universidade de Brasília, UnB, Brasília 70910-900, DF, Brazil., Rocha JA; Campus São Bernardo, Universidade Federal do Maranhão, UFMA, São Bernardo 65550-000, MA, Brazil., Arcanjo DDR; Department of Biophysics and Physiology, Federal University of Piauí, Teresina 64049-550, PI, Brazil., Batagin-Neto A; Programa de Pós-Graduação em Ciência e Tecnologia de Materiais (POSMAT), School of Sciences, São Paulo State University (UNESP), Bauru 17033-360, SP, Brazil.; Institute of Sciences and Engineering, São Paulo State University (UNESP), Itapeva 18409-010, SP, Brazil., Borges TKS; Núcleo de Pesquisa em Morfologia e Imunologia Aplicada, NuPMIA, Faculdade de Medicina, Universidade de Brasília, UnB, Brasília 70910-900, DF, Brazil., Gonçalves J; imed.ULisboa-Research Institute for Medicines, Faculty of Pharmacy, University of Lisbon, 1649-003 Lisbon, Portugal., Brand GD; Instituto de Química, IQ, Universidade de Brasília, UnB, Brasília 70910-900, DF, Brazil., Freitas-Junior LHG; Department of Microbiology, Institute of Biomedical Sciences, University of Sao Paulo, São Paulo 05508-000, SP, Brazil., Eaton P; Laboratório Associado para a Química Verde/Rede de Química e Tecnologia (LAQV/REQUIMTE), Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade do Porto, 4169-007 Porto, Portugal.; School of Chemistry, The Bridge, University of Lincoln, Lincoln LN6 7EL, UK., Marani M; IPEEC-CONICET, Consejo Nacional de Investigaciones Científicas y Técnicas, Puerto Madryn 9120, Argentina., Kato MJ; Instituto de Química (IQ), Universidade de São Paulo (USP), São Paulo 05508-900, SP, Brazil., Plácido A; Laboratório Associado para a Química Verde/Rede de Química e Tecnologia (LAQV/REQUIMTE), Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade do Porto, 4169-007 Porto, Portugal., Leite JRSA; Núcleo de Pesquisa em Morfologia e Imunologia Aplicada, NuPMIA, Faculdade de Medicina, Universidade de Brasília, UnB, Brasília 70910-900, DF, Brazil.

المصدر: Pharmaceutics [Pharmaceutics] 2024 Jan 29; Vol. 16 (2). Date of Electronic Publication: 2024 Jan 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101534003 Publication Model: Electronic Cited Medium: Print ISSN: 1999-4923 (Print) Linking ISSN: 19994923 NLM ISO Abbreviation: Pharmaceutics Subsets: PubMed not MEDLINE

المؤلفون: Cioffi VB; Laboratory of Applied Structural Biology, Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1374, São Paulo, 05508-000, Brazil., de Castro-Amarante MF; Laboratory of Vaccine Development, Department of Microbiology, University of São Paulo, Institute of Biomedical Sciences, Av. Prof. Lineu Prestes, 1374, São Paulo, 05508-000, Brazil., Lulla A; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge, CB2 1GA, UK., Andreata-Santos R; Laboratory of Vaccine Development, Department of Microbiology, University of São Paulo, Institute of Biomedical Sciences, Av. Prof. Lineu Prestes, 1374, São Paulo, 05508-000, Brazil., Cruz MC; Core Facilities to Support Research (CEFAP), Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, São Paulo, 173005508-000, Brazil., Moreno ACR; Laboratory of Vaccine Development, Department of Microbiology, University of São Paulo, Institute of Biomedical Sciences, Av. Prof. Lineu Prestes, 1374, São Paulo, 05508-000, Brazil.; Vaccine Development Laboratory, Butantan Institute, Av. Vital Brasil, 1500, São Paulo, SP, 05503-900, Brazil., de Oliveira Silva M; Phenotypic Screening Platform, Department of Microbiology, University of São Paulo, Institute of Biomedical Sciences, Av. Prof. Lineu Prestes, 1374, São Paulo, 05508-000, Brazil., de Miranda Peres B; Phenotypic Screening Platform, Department of Microbiology, University of São Paulo, Institute of Biomedical Sciences, Av. Prof. Lineu Prestes, 1374, São Paulo, 05508-000, Brazil., de Freitas Junior LHG; Phenotypic Screening Platform, Department of Microbiology, University of São Paulo, Institute of Biomedical Sciences, Av. Prof. Lineu Prestes, 1374, São Paulo, 05508-000, Brazil., Moraes CB; Phenotypic Screening Platform, Department of Microbiology, University of São Paulo, Institute of Biomedical Sciences, Av. Prof. Lineu Prestes, 1374, São Paulo, 05508-000, Brazil., Durigon EL; Laboratory of Clinical and Molecular Virology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1374, São Paulo, 05508-000, Brazil.; Institut Pasteur de São Paulo, Av. Prof. Lucio Martins Rodrigues, 370, São Paulo, 05508-020, Brazil., Gordon NC; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge, CB2 1GA, UK., Hyvönen M; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge, CB2 1GA, UK., de Souza Ferreira LC; Laboratory of Vaccine Development, Department of Microbiology, University of São Paulo, Institute of Biomedical Sciences, Av. Prof. Lineu Prestes, 1374, São Paulo, 05508-000, Brazil.; Institut Pasteur de São Paulo, Av. Prof. Lucio Martins Rodrigues, 370, São Paulo, 05508-020, Brazil., Balan A; Laboratory of Applied Structural Biology, Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1374, São Paulo, 05508-000, Brazil. abalan@usp.br.

المصدر: Scientific reports [Sci Rep] 2023 Oct 05; Vol. 13 (1), pp. 16821. Date of Electronic Publication: 2023 Oct 05.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Pyrococcus furiosus*/metabolism , COVID-19*, Humans ; Animals ; Mice ; Epitopes ; Spike Glycoprotein, Coronavirus/metabolism ; Antibodies, Viral ; Viral Envelope Proteins ; SARS-CoV-2 ; Peptides/chemistry ; Antibodies, Neutralizing

المؤلفون: Oliveira VDS; Department of Pharmacy, Health Sciences Center, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, 59012-570, Brazil., Silva CC; School of Technology, State University of Amazonas, Manaus, Amazonas, 69065-020, Brazil., de Freitas Oliveira JW; Department of Pharmacy, Health Sciences Center, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, 59012-570, Brazil., da Silva MS; Department of Pharmacy, Health Sciences Center, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, 59012-570, Brazil.; Global Health and Tropical Medicine, Institute of Hygiene and Tropical Medicine, NOVA University Lisbon, Lisbon, 1800-166, Portugal., Ferreira PG; Department of Pharmaceutical Technology, Faculty of Pharmacy, Fluminense Federal University, Niterói, Rio de Janeiro, 24241-002, Brazil., da Siva FC; Institute of Chemistry, Fluminense Federal University, Niterói, Rio de Janeiro, 24020-150, Brazil., Ferreira VF; Department of Pharmaceutical Technology, Faculty of Pharmacy, Fluminense Federal University, Niterói, Rio de Janeiro, 24241-002, Brazil., Barbosa EG; Department of Pharmacy, Health Sciences Center, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, 59012-570, Brazil., Barbosa CG; Department of Microbiology, Institute of Biomedical Sciences, University of Sao Paulo, São Paulo, São Paulo, 05508-900, Brazil., Moraes CB; Department of Microbiology, Institute of Biomedical Sciences, University of Sao Paulo, São Paulo, São Paulo, 05508-900, Brazil.; Department of Pharmaceutical Sciences, Federal University of São Paulo, São Paulo, São Paulo, 09913-030, Brazil., Freitas-Junior LHG; Department of Microbiology, Institute of Biomedical Sciences, University of Sao Paulo, São Paulo, São Paulo, 05508-900, Brazil., Converti A; Department of Civil, Chemical and Environmental Engineering, University of Genoa, Pole of Chemical Engineering, via Opera Pia 15, 16145, Genoa, Italy., Lima ÁAN; Department of Pharmacy, Health Sciences Center, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, 59012-570, Brazil.

المصدر: Journal of drug delivery science and technology [J Drug Deliv Sci Technol] 2023 Mar; Vol. 81, pp. 104229. Date of Electronic Publication: 2023 Feb 08.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: France NLM ID: 101214432 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1773-2247 (Print) Linking ISSN: 17732247 NLM ISO Abbreviation: J Drug Deliv Sci Technol Subsets: PubMed not MEDLINE

المؤلفون: Freire MCLC; São Carlos Institute of Physics, University of Sao Paulo, Avenida João Dagnone, 1100, São Carlos 13563-120, SP, Brazil., Noske GD; São Carlos Institute of Physics, University of Sao Paulo, Avenida João Dagnone, 1100, São Carlos 13563-120, SP, Brazil., Bitencourt NV; Department of Biochemistry and Organic Chemistry, Institute of Chemistry, São Paulo State University (UNESP), Araraquara 14800-060, SP, Brazil., Sanches PRS; Department of Biochemistry and Organic Chemistry, Institute of Chemistry, São Paulo State University (UNESP), Araraquara 14800-060, SP, Brazil., Santos-Filho NA; Department of Biochemistry and Organic Chemistry, Institute of Chemistry, São Paulo State University (UNESP), Araraquara 14800-060, SP, Brazil., Gawriljuk VO; São Carlos Institute of Physics, University of Sao Paulo, Avenida João Dagnone, 1100, São Carlos 13563-120, SP, Brazil., de Souza EP; Department of Genetics and Evolution, Federal University of São Carlos, Rodovia Washington Luís km 235, São Carlos 13565-905, SP, Brazil., Nogueira VHR; São Carlos Institute of Physics, University of Sao Paulo, Avenida João Dagnone, 1100, São Carlos 13563-120, SP, Brazil., de Godoy MO; São Carlos Institute of Physics, University of Sao Paulo, Avenida João Dagnone, 1100, São Carlos 13563-120, SP, Brazil., Nakamura AM; São Carlos Institute of Physics, University of Sao Paulo, Avenida João Dagnone, 1100, São Carlos 13563-120, SP, Brazil., Fernandes RS; São Carlos Institute of Physics, University of Sao Paulo, Avenida João Dagnone, 1100, São Carlos 13563-120, SP, Brazil., Godoy AS; São Carlos Institute of Physics, University of Sao Paulo, Avenida João Dagnone, 1100, São Carlos 13563-120, SP, Brazil., Juliano MA; The Sao Paulo School of Medicine, Federal University of São Paulo, Rua Três de Maio, 100, São Paulo 04044-020, SP, Brazil., Peres BM; Department of Microbiology, Institute of Biomedical Sciences, University of Sao Paulo, Av. Prof. Lineu Prestes, 1374, São Paulo 05508-900, SP, Brazil., Barbosa CG; Department of Microbiology, Institute of Biomedical Sciences, University of Sao Paulo, Av. Prof. Lineu Prestes, 1374, São Paulo 05508-900, SP, Brazil., Moraes CB; Department of Pharmaceutical Sciences, Federal University of São Paulo, Rua São Nicolau, 210, Diadema 09913-030, SP, Brazil., Freitas-Junior LHG; Department of Microbiology, Institute of Biomedical Sciences, University of Sao Paulo, Av. Prof. Lineu Prestes, 1374, São Paulo 05508-900, SP, Brazil., Cilli EM; Department of Biochemistry and Organic Chemistry, Institute of Chemistry, São Paulo State University (UNESP), Araraquara 14800-060, SP, Brazil., Guido RVC; São Carlos Institute of Physics, University of Sao Paulo, Avenida João Dagnone, 1100, São Carlos 13563-120, SP, Brazil., Oliva G; São Carlos Institute of Physics, University of Sao Paulo, Avenida João Dagnone, 1100, São Carlos 13563-120, SP, Brazil.

المصدر: Molecules (Basel, Switzerland) [Molecules] 2021 Aug 12; Vol. 26 (16). Date of Electronic Publication: 2021 Aug 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules

مواضيع طبية MeSH: SARS-CoV-2*/drug effects , Antiviral Agents*/pharmacology , Antiviral Agents*/chemistry , Peptides*/chemistry , Peptides*/pharmacology, Humans ; Protease Inhibitors/pharmacology ; Protease Inhibitors/chemistry ; COVID-19 Drug Treatment ; Coronavirus 3C Proteases/antagonists & inhibitors ; Coronavirus 3C Proteases/metabolism ; Coronavirus 3C Proteases/chemistry ; Coronavirus Papain-Like Proteases/antagonists & inhibitors ; Coronavirus Papain-Like Proteases/chemistry ; Coronavirus Papain-Like Proteases/metabolism ; Molecular Docking Simulation ; COVID-19/virology ; Vero Cells ; Chlorocebus aethiops

المؤلفون: Gomes JC; Instituto de Química de São Carlos, Universidade de São Paulo, São Carlos, São Paulo, Brazil., Cianni L; Grupo de Química Medicinal do IQSC/USP, Instituto de Química de São Carlos, Universidade de São Paulo, São Carlos, São Paulo, Brazil., Ribeiro J; Grupo de Química Medicinal do IQSC/USP, Instituto de Química de São Carlos, Universidade de São Paulo, São Carlos, São Paulo, Brazil., Dos Reis Rocho F; Grupo de Química Medicinal do IQSC/USP, Instituto de Química de São Carlos, Universidade de São Paulo, São Carlos, São Paulo, Brazil., da Costa Martins Silva S; Grupo de Química Medicinal do IQSC/USP, Instituto de Química de São Carlos, Universidade de São Paulo, São Carlos, São Paulo, Brazil., Batista PHJ; Grupo de Química Medicinal do IQSC/USP, Instituto de Química de São Carlos, Universidade de São Paulo, São Carlos, São Paulo, Brazil., Moraes CB; Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil., Franco CH; Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil., Freitas-Junior LHG; Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil., Kenny PW; Grupo de Química Medicinal do IQSC/USP, Instituto de Química de São Carlos, Universidade de São Paulo, São Carlos, São Paulo, Brazil., Leitão A; Grupo de Química Medicinal do IQSC/USP, Instituto de Química de São Carlos, Universidade de São Paulo, São Carlos, São Paulo, Brazil., Burtoloso ACB; Instituto de Química de São Carlos, Universidade de São Paulo, São Carlos, São Paulo, Brazil., de Vita D; Grupo de Química Medicinal do IQSC/USP, Instituto de Química de São Carlos, Universidade de São Paulo, São Carlos, São Paulo, Brazil., Montanari CA; Grupo de Química Medicinal do IQSC/USP, Instituto de Química de São Carlos, Universidade de São Paulo, São Carlos, São Paulo, Brazil. Electronic address: Carlos.Montanari@usp.br.

المصدر: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2019 Nov 15; Vol. 27 (22), pp. 115083. Date of Electronic Publication: 2019 Aug 28.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Amides/*chemistry , Cysteine Endopeptidases/*chemical synthesis , Protozoan Proteins/*antagonists & inhibitors , Protozoan Proteins/*chemical synthesis, Molecular Structure ; Structure-Activity Relationship