المؤلفون: Fluhrer, Regina, Grammer, Gudula, Israel, Lars, Condron, Margaret M, Haffner, Christof, Friedmann, Elena, Böhland, Claudia, Imhof, Axel, Martoglio, Bruno, Teplow, David B, Haass, Christian

المصدر: Nature Cell Biology. 8(8)

مصطلحات موضوعية: Amino Acid Sequence, Amyloid Precursor Protein Secretases, Aspartic Acid Endopeptidases, Binding Sites, Cell Line, Cytosol, Endopeptidases, Humans, Intracellular Membranes, Molecular Sequence Data, Mutation, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Tumor Necrosis Factor-alpha, Zebrafish Proteins, Biological Sciences, Medical and Health Sciences, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/59c2q1jk

المؤلفون: Fluhrer, Regina, Grammer, Gudula, Israel, Lars, Condron, Margaret M, Haffner, Christof, Friedmann, Elena, Böhland, Claudia, Imhof, Axel, Martoglio, Bruno, Teplow, David B, Haass, Christian

المصدر: Nature cell biology. 8(8)

مصطلحات موضوعية: Cell Line, Intracellular Membranes, Cytosol, Humans, Endopeptidases, Tumor Necrosis Factor-alpha, Zebrafish Proteins, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Binding Sites, Amino Acid Sequence, Mutation, Molecular Sequence Data, Amyloid Precursor Protein Secretases, Aspartic Acid Endopeptidases, Developmental Biology, Biological Sciences, Medical and Health Sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/59c2q1jk

المؤلفون: Friedmann, Elena

مصطلحات موضوعية: SIGNALPEPTIDASEN (ENZYME), PROTEOLYSIS (METABOLISM), TUMORNEKROSEFAKTOR (IMMUNOLOGIE), SIGNAL PEPTIDASES (ENZYMES), PROTEOLYSE (METABOLISMUS), TUMOR NECROSIS FACTOR (IMMNUNOLOGY), PEPTIDHYDROLASEN, PROTEASEN (ENZYME), PEPTIDE HYDROLASES, PROTEASES (ENZYMES), Life sciences

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ee5db7a39b7d94bce8d509b483fd50c5

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المؤلفون: Friedmann, Elena, Hauben, Ehud, Maylandt, Kerstin, Schleeger, Simone, Vreugde, Sarah, Lichtenthaler, Stefan F., Kuhn, Peer-Hendrik, Stauffer, Daniela, Rovelli, Giorgio, Martoglio, Bruno

المصدر: Nature Cell Biology; Aug2006, Vol. 8 Issue 8, p843-848, 6p, 3 Diagrams, 1 Graph

مصطلحات موضوعية: PEPTIDES, PROTEOLYTIC enzymes, PROTEOLYSIS, CELL membranes, TUMOR necrosis factors, CYTOKINES

المؤلفون: Litovchick, Larisa, Friedmann, Elena, Shaltiel, Shmuel

المصدر: Journal of Biological Chemistry; September 2002, Vol. 277 Issue: 37 p34413-34423, 11p

المؤلفون: Friedmann, Elena, Salzberg, Yehuda, Weinberger, Adina, Shaltiel, Shmuel, Gerst, Jeffrey E

المصدر: Journal of Biological Chemistry; September 2002, Vol. 277 Issue: 38 p35274-81, 8p

المؤلفون: Friedmann E; Institute of Biochemistry, Swiss Federal Institute of Technology (ETH), ETH-Hoenggerberg, 8093 Zurich, Switzerland., Lemberg MK, Weihofen A, Dev KK, Dengler U, Rovelli G, Martoglio B

المصدر: The Journal of biological chemistry [J Biol Chem] 2004 Dec 03; Vol. 279 (49), pp. 50790-8. Date of Electronic Publication: 2004 Sep 21.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Print ISSN: 0021-9258 (Print) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Aspartic Acid Endopeptidases/*chemistry , Membrane Proteins/*chemistry, Binding Sites ; Blotting, Western ; Catalysis ; Catalytic Domain ; Cell Line ; Cell-Free System ; Cloning, Molecular ; Cytosol/metabolism ; DNA, Complementary/metabolism ; Electrophoresis, Polyacrylamide Gel ; Fluorescent Antibody Technique, Indirect ; Gene Library ; Glycosylation ; HeLa Cells ; Humans ; Microscopy, Fluorescence ; Oligonucleotide Array Sequence Analysis ; Phylogeny ; Plasmids/metabolism ; Polysaccharides/chemistry ; Presenilin-1 ; Protein Biosynthesis ; Protein Structure, Tertiary ; Protein Transport ; RNA, Messenger/metabolism ; Tissue Distribution ; Transcription, Genetic

المؤلفون: Weihofen A; Institute of Biochemistry, Swiss Federal Institute of Technology (ETH), ETH-Hoenggerberg, 8093 Zurich, Switzerland., Lemberg MK, Friedmann E, Rueeger H, Schmitz A, Paganetti P, Rovelli G, Martoglio B

المصدر: The Journal of biological chemistry [J Biol Chem] 2003 May 09; Vol. 278 (19), pp. 16528-33. Date of Electronic Publication: 2003 Mar 05.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Print ISSN: 0021-9258 (Print) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Aspartic Acid Endopeptidases/*antagonists & inhibitors , Endopeptidases/*drug effects , Enzyme Inhibitors/*pharmacology, Alzheimer Disease/drug therapy ; Alzheimer Disease/enzymology ; Amyloid Precursor Protein Secretases ; Enzyme Activation/drug effects ; Enzyme Inhibitors/therapeutic use ; Humans ; Substrate Specificity