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المؤلفون: C. Chris Yun, Yiran Han, Songbai Lin, Peijian He, Kayte A. Jenkin
المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 695-716 (2022)
Cellular and Molecular Gastroenterology and Hepatologyمصطلحات موضوعية: NEDD4, RC799-869, CTX, cholera toxin, medicine.disease_cause, IEC, intestinal epithelial cell, Enteropathogenic Escherichia coli, Mice, EPEC, enteropathogenic E coli, PCR, polymerase chain reaction, Ubiquitin, Phosphorylation, Ub, ubiquitin, ANOVA, analysis of variance, Original Research, biology, Sodium-Hydrogen Exchanger 3, Chemistry, FSK, forskolin, Cholera toxin, Gastroenterology, Diseases of the digestive system. Gastroenterology, DUB, deubiquitinating enzyme, Ubiquitin ligase, Diarrhea, DRA, down-regulated in adenoma, NHE, Na+/H+ exchanger, Sodium Transporter, hNHE3, human NHE3, sh, short hairpin, medicine.symptom, Cholera Toxin, macromolecular substances, PKC, protein kinase C, medicine, Animals, Humans, CFTR, cystic fibrosis transmembrane conductance regulator, IF, immunofluorescence, Protein kinase A, HBSS, Hank’s balanced saline solution, Hepatology, Sodium, Ubiquitination, Wild type, ENaC, epithelial Na+ channel, WT, wild-type, Molecular biology, pHi, intracellular pH, biology.protein, Nedd4, neural precursor cell expressed, developmentally down-regulated 4, USP, ubiquitin-specific peptidase, PKA, protein kinase A, SD, standard deviation
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المؤلفون: Narihito Nagoshi, Taro Matsumoto, Rina Fujii-Tezuka, Ichiro Morioka, Hideyuki Okano, Shori Takahashi, Hideo Mugishima, Mika Ishige-Wada
المصدر: Regenerative Therapy
Regenerative Therapy, Vol 16, Iss, Pp 1-11 (2021)مصطلحات موضوعية: 0301 basic medicine, Medicine (General), DMEM, Dulbecco's modified Eagle medium, MSCs, mesenchymal stem cells, WJ, Wharton's jelly, FGF-2, fibroblast growth factor-2, ASMA, α-smooth muscle actin, vWF, von Willebrand factor, PDGF, platelet-derived growth factor, 0302 clinical medicine, Immunophenotyping, βME, β-mercaptoethanol, DAPI, 4′,6-diamino-2-phenylindole, p75 neurotrophin receptor, UA, umbilical artery, CFU-F, colony-forming unit fibroblast, FSK, forskolin, EdU, 5-ethynyl-2′-deoxyuridine, UC, umbilical cord, Neural crest, EGFP, enhanced green fluorescent protein, Cell biology, medicine.anatomical_structure, NCSCs, neural crest-derived stem cells, CD146, Original Article, Pericyte, Neural crest stem cells, Stem cell, α-MEM, alpha-modified minimum essential medium, BDNF, bone-derived neurotrophic factor, PBS, phosphate-buffered saline, Biomedical Engineering, Neurosphere, Biology, p75NTR, p75 neurotrophin receptor, Biomaterials, MAP2, microtubule-associated protein 2, 03 medical and health sciences, R5-920, FBS, fetal bovine serum, medicine, CD90, NG2, neuron-glial antigen 2, Umbilical cord, EGF, epidermal growth factor, QH573-671, Mesenchymal stem cell, GFAP, glial fibrillary acidic protein, NF200, neurofilament 200, TBS, Tris-buffered saline, 030104 developmental biology, UV, umbilical vein, Mesenchymal stem cells, sense organs, Cytology, RA, all-trans-retinoic acid, 030217 neurology & neurosurgery, Developmental Biology
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المؤلفون: Randal S. Tibbetts, Weiyan Jia, Sang Hwa Kim, Cheng-Guo Wu, Yongna Xing
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, BS1/2, B56 binding site 1/2, Serine 133, B56γ, Biochemistry, Mice, PP2A, protein phosphatase 2A, Cyclic AMP, PKA, Protein Phosphatase 2, Phosphorylation, KID, kinase-inducible domain, Cyclic AMP Response Element-Binding Protein, Cells, Cultured, SLiM, CLM, calicheamicin γ1, biology, CREB, Chemistry, PP2A, Cell biology, Histone, KIX domain, KID-interacting domain, Casein kinase 1, CK1/2, casein kinase 1/2, casein kinase, Fsk, Forskolin, SLiM, short linear motif, Protein Binding, Signal Transduction, Research Article, Transcriptional Activation, CRTCs, cAMP-regulated transcriptional coactivators, 03 medical and health sciences, cAMP, Animals, Humans, PMA, Phorbol 12-myristate 13-acetate, CREB-binding protein, Binding site, CBP, CREB-binding protein, Molecular Biology, Binding Sites, 030102 biochemistry & molecular biology, Cell Biology, Protein phosphatase 2, 030104 developmental biology, biology.protein, CREB, cAMP response element-binding protein, HeLa Cells
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e826d90c7834633ab89254c958a2d3a
https://doi.org/10.1016/j.jbc.2021.100908 -
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المؤلفون: Donald H. Maurice, Ariana N. Jacobs, Alastair V. Ferguson, M. Bibiana Umana, Nicholas J. Simpson, Jodi L. MacKeil, Darrin Payne, Fabien Hubert, Paulina Brzezinska, Jonah Burke-Kleinman
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, PDE, phosphodiesterase, ROI, region of interest, Biochemistry, Adenylyl cyclase, STIM1, stromal interaction molecule 1, chemistry.chemical_compound, Cell Movement, Cyclic AMP, HASMC, human arterial smooth muscle cell, SBMB, smooth muscle basal media, Forskolin, biology, ORAI1, Chemistry, phosphodiesterase 1C, human arterial smooth muscle cells, CPA, cyclopiazonic acid, Phosphodiesterase, Ca2+, calcium, Arteries, Store-operated calcium entry, Cell biology, Second messenger system, Signal Transduction, Research Article, adenylate cyclase, Calmodulin, cAMP, cyclic AMP, SOCE, store-operated calcium entry, FRET, fluorescence resonance energy transfer, Gene Expression Regulation, Enzymologic, 03 medical and health sciences, PDE1C, phosphodiesterase 1C, Humans, LEP, leading-edge protrusion, phosphodiesterases, Protein kinase A, Molecular Biology, Muscle Cells, calcium, 030102 biochemistry & molecular biology, store-operated calcium entry, Biological Transport, Cell Biology, Cyclic Nucleotide Phosphodiesterases, Type 1, Kinetics, fsk, forskolin, 030104 developmental biology, ADCY, adenylyl cyclase, HBSS, Hank's balanced salt solution, biology.protein, BSA, bovine serum albumin, PKA, protein kinase A, DAPI, 4′,6-diamidino-2-phenylindole
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ac827c2d0c38ce84dc27d64aef75013
https://doi.org/10.1016/j.jbc.2021.100606 -
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المؤلفون: Fiona M. Gribble, Eleftheria Diakogiannaki, Leslie L Glass, Catherine E. Moss, Carol Lenaghan, Marianne Wedin, Mohammad Bohlooly-Y, David M. Smith, Ramona Pais, Frank Reimann
المساهمون: Glass, Leslie [0000-0002-3559-4705], Gribble, Fiona [0000-0002-4232-2898], Reimann, Frank [0000-0001-9399-6377], Apollo - University of Cambridge Repository
المصدر: Peptides
مصطلحات موضوعية: Male, IBMX, 3-isobutyl-1-methylxanthine, 0301 basic medicine, IBMX, Physiology, Fsk, forskolin, Peroxisome proliferator-activated receptor, Second Messenger Systems, Biochemistry, Receptors, G-Protein-Coupled, chemistry.chemical_compound, Endocrinology, Glucagon-Like Peptide 1, Cyclic AMP, Receptor, Cells, Cultured, chemistry.chemical_classification, Primary (chemistry), digestive, oral, and skin physiology, GLP-1, glucagon-like peptide-1, Incretin, Proglucagon, GPR119, Female, PPAR, peroxisome-proliferator-activated receptor, hormones, hormone substitutes, and hormone antagonists, endocrine system, medicine.medical_specialty, Enteroendocrine Cells, Primary Cell Culture, OEA, oleoylethanolamide, Mice, Transgenic, Biology, Article, 03 medical and health sciences, Cellular and Molecular Neuroscience, Internal medicine, medicine, Animals, WT, wildtype, Secretion, 2-OG, 2-oleoylglycerol, Olive Oil, KO, knockout, 030104 developmental biology, chemistry, Corn Oil, GLP-1
وصف الملف: application/pdf
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المؤلفون: Dmitry Akhmedov, Kavitha Rajendran, Nicholas J. Justice, Jingqi Fu, Mark Nixon, Rebecca Berdeaux, Randi Stewart-Fitzgibbon, Micah Gibson, Yisel A. Rivera-Molina, Maria G. Mendoza-Rodriguez, Eric D. Berglund
المصدر: Molecular Metabolism, Vol 5, Iss 1, Pp 34-46 (2016)
Molecular Metabolismمصطلحات موضوعية: 0301 basic medicine, Glucose uptake, FGF21, fibroblast growth factor 21, HDAC, histone deacetylase, Pepck, phosphoenolpyruvate carboxykinase, SIK, salt inducible kinase, GIR, glucose infusion rate, HFD, high fat diet, AMP-activated protein kinase, CRTC, Glucose homeostasis, SIK1, Glucose tolerance test, medicine.diagnostic_test, CREB, FSK, forskolin, Glgn, glucagon, WAT, white adipose tissue, Glut, glucose transporter, cAMP, cyclic adenosine monophosphate, IBMX, 3-isobutyl-1-methylxantine, medicine.anatomical_structure, G6pase, glucose 6-phosphatase, GDR, glucose disposal rate, GTT, glucose tolerance test, Original Article, HSP, heat shock protein, CRTC, CREB regulated transcription coactivator, lcsh:Internal medicine, medicine.medical_specialty, Pgc, peroxisome proliferator-activated receptor gamma coactivator, Biology, FOXO1, forkhead box protein O1, AKT, protein kinase B, 03 medical and health sciences, Insulin resistance, CHX, cycloheximide, Internal medicine, medicine, lcsh:RC31-1245, Molecular Biology, ITT, insulin tolerance test, PTT, pyruvate tolerance test, Gluconeogenesis, Glucose transporter, Skeletal muscle, Cell Biology, medicine.disease, BAT, brown adipose tissue, AMPK, AMP-activated protein kinase, Insulin receptor, 030104 developmental biology, Endocrinology, Salt inducible kinase, biology.protein, CREB, cAMP response element-binding protein, EndoRa, endogenous rate of glucose appearance
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المؤلفون: Sandhiya, Ramachandran, Swetha, Loganathan, Vinnie, Cheeran, Soniya, Charles, Ganesh, Munuswamy-Ramanujan, Mohankumar, Ramasamy, Vijay, Raj, Kanchana, Mala
المصدر: Leukemia Research Reports
مصطلحات موضوعية: HCY, homocysteine, cAMP, cyclic AMP, macromolecular substances, CVD, cardiovascular disease, Article, MET, metformin, ROS, reactive oxygen species, NAD+, nicotinamide adenine dinucleotide, polycyclic compounds, ADMA, asymmetric dimethylarginine, HTRF, homogenous time-resolved fluorescence, Endothelial dysfunction, Methyltransferase, Cancer, PRMT1, protein arginine methyltransferase1, SAHH, s-adenosylhomocysteine hydrolase, organic chemicals, L-cit, L-citrulline, FSK, forskolin, SAH, s-adenosylhomocysteine, technology, industry, and agriculture, eNOS, endothelial nitric oxide synthase, L-arg, L-arginine, SIRT1, sirtuin1, Cardiovascular disease, DOX, doxorubicin, Metformin, carbohydrates (lipids), DDAH, dimethylarginine diaminohydrolase, OS, oxidative stress, SAM, s-adenosylmethionine, Forskolin, CT, chemotherapy, SAH-A, SAH accumulation
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المؤلفون: Margarida D. Amaral, Maria Margarida Ramos, Karina Mendes, Inna Uliyakina, Amparo Solé, Luka A. Clarke, Carlos M. Farinha, Juan Antonio Pastor, Nikhil T. Awatade
المصدر: Ebiomedicine
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
EBioMedicine, Vol 2, Iss 2, Pp 147-153 (2015)مصطلحات موضوعية: Epithelial sodium channel, Cell, lcsh:Medicine, Fsk, forskolin, Pharmacology, SEM, standard error of the mean, Cystic fibrosis, General Biochemistry, Genetics and Molecular Biology, Ivacaftor, TEER, transepithelial electrical resistance, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, medicine, CFTR, cystic fibrosis transmembrane conductance regulator, Gen, Genistein, 030304 developmental biology, Rte, transepithelial resistance, CF, cystic fibrosis, lcsh:R5-920, 0303 health sciences, Lung, biology, business.industry, lcsh:R, Lumacaftor, ENaC, epithelial Na+ channel, General Medicine, medicine.disease, Personalized medicine, Vte, transepithelial voltage, Cystic fibrosis transmembrane conductance regulator, 3. Good health, Rare diseases, medicine.anatomical_structure, chemistry, Mutation-specific therapies, 030220 oncology & carcinogenesis, Immunology, biology.protein, lcsh:Medicine (General), business, Innovative treatments, Ex vivo, (DeltaIeq-sc), equivalent short-circuit currents, medicine.drug, HBE (cells), human bronchial epithelial cells
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المصدر: Biochemical Journal
مصطلحات موضوعية: IBMX, 3-isobutyl-1-methylxanthine, GTP-Binding Protein beta Subunits, Iso, isoproterenol, GTP-Binding Protein alpha Subunits, Gi-Go, Biochemistry, Adenylyl cyclase, AUC, area under the curve, chemistry.chemical_compound, MEM, minimal essential medium, 0302 clinical medicine, GTP-Binding Protein gamma Subunits, Muscarinic acetylcholine receptor, Cyclic AMP, Receptors, Somatostatin, Phosphorylation, AC, adenylyl cyclase, Protein Kinase C, HA, haemagglutinin, 0303 health sciences, Somatostatin receptor, protein kinase C (PKC), FSK, forskolin, adenylyl cyclase 2 (AC2), Cell biology, somatostatin receptor, Second messenger system, Single-Cell Analysis, Adenylyl Cyclases, Research Article, CCh, carbachol, cAMP, cyclic AMP, G protein, Biology, FRET, fluorescence resonance energy transfer, muscarinic receptor, HEK, human embryonic kidney, 03 medical and health sciences, CFP, cyan fluorescent protein, PKC, protein kinase C, Animals, Humans, Molecular Biology, Protein kinase C, GPCR, G-protein-coupled receptor, 030304 developmental biology, Receptor, Muscarinic M3, CC, chelerythrine chloride, PMA, phorbol myristic acid, Cell Biology, YFP, yellow fluorescent protein, Rats, Enzyme Activation, HEK293 Cells, chemistry, 13. Climate action, Mutation, GTP-Binding Protein alpha Subunits, Gq-G11, Carbachol, PKA, protein kinase A, PGE1, prostaglandin E1, SST, somatostatin, 030217 neurology & neurosurgery
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dd11b40a8af35fdf66cda97c3392abb
https://doi.org/10.1042/bj20120279 -
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المؤلفون: Timothy M. Palmer, Sarah Jones
المصدر: Cellular Signalling
مصطلحات موضوعية: Male, RHOA, Cellular differentiation, Fsk, forskolin, Epithelial cells, Neuroendocrine differentiation, RACK1, receptor of activated C kinase 1, Phosphoserine, bFGF, basic fibroblast growth factor, 0302 clinical medicine, PKA, cAMP-dependent protein kinase, ERK, extracellular signal-regulated kinase, Cyclic AMP, Tumor Cells, Cultured, Phosphorylation, Rho-associated protein kinase, Neuroendocrine cell, PSA, prostate-specific antigen, 0303 health sciences, Prostate cancer, 3. Good health, Phenotype, medicine.anatomical_structure, CREB, cAMP response element binding protein, 030220 oncology & carcinogenesis, EPAC, exchange protein directly activated by cAMP, NE, neuroendocrine, 6-Bnz-cAMP, N6-benzoyl-cAMP, cAMP, cyclic AMP, C3T, cell-permeable C. botulinum C3 transferase, NGF, nerve growth factor, PCa, prostate cancer, Biology, Article, 03 medical and health sciences, LNCaP, medicine, Humans, Protein kinase A, 030304 developmental biology, Prostatic Neoplasms, RhoA, Cell Biology, Cyclic AMP-Dependent Protein Kinases, Carcinoma, Neuroendocrine, ROCK, Rho-associated protein kinase, Cancer research, biology.protein, rhoA GTP-Binding Protein