المؤلفون: Laranjeira ABA; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Kong T; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Snyder SC; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Fulbright MC; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Fisher DAC; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Starczynowski DT; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH.; Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH., Oh ST; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO.; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO.; Immunomonitoring Laboratory, Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO.

المصدر: Blood [Blood] 2024 Jun 06; Vol. 143 (23), pp. 2414-2424.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

مواضيع طبية MeSH: Myeloproliferative Disorders*/genetics , Myeloproliferative Disorders*/pathology , Myeloproliferative Disorders*/metabolism , NF-kappa B*/metabolism , Signal Transduction*, Animals ; Mice ; Humans ; Mice, Knockout ; Interleukin-1 Receptor-Associated Kinases/metabolism ; Interleukin-1 Receptor-Associated Kinases/genetics ; Transcription Factor RelA/metabolism ; Transcription Factor RelA/genetics

المؤلفون: Collins TB; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Laranjeira ABA; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Kong T; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Fulbright MC; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Fisher DAC; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO., Sturgeon CM; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai School of Medicine, New York, NY; Department of Cell, Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY., Batista LFZ; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO; Center for Genome Integrity, Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO., Oh ST; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO; Immunomonitoring Laboratory, Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO. Electronic address: stoh@wustl.edu.

المصدر: Experimental hematology [Exp Hematol] 2024 Apr; Vol. 132, pp. 104178. Date of Electronic Publication: 2024 Feb 09.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Inc Country of Publication: Netherlands NLM ID: 0402313 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2399 (Electronic) Linking ISSN: 0301472X NLM ISO Abbreviation: Exp Hematol Subsets: MEDLINE

مواضيع طبية MeSH: Neoplasms* , Myeloproliferative Disorders*/genetics , Myeloproliferative Disorders*/metabolism, Humans ; Erythropoiesis/genetics ; Janus Kinase 2/genetics ; Janus Kinase 2/metabolism ; Signal Transduction ; Mutation ; Repressor Proteins/genetics ; Repressor Proteins/metabolism ; Nuclear Proteins/genetics ; Protein-Arginine N-Methyltransferases/genetics ; Protein-Arginine N-Methyltransferases/metabolism

المؤلفون: He F; Division of Hematology, Department of Medicine, and., Laranjeira AB; Division of Hematology, Department of Medicine, and., Kong T; Division of Hematology, Department of Medicine, and., Lin S; Division of Hematology, Department of Medicine, and., Ashworth KJ; Division of Hematology & Oncology, Department of Pediatrics, School of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., Liu A; Division of Hematology & Oncology, Department of Pediatrics, School of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., Lasky NM; Division of Hematology & Oncology, Department of Pediatrics, School of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., Fisher DA; Division of Hematology, Department of Medicine, and., Cox MJ; Division of Hematology, Department of Medicine, and., Fulbright MC; Division of Hematology, Department of Medicine, and., Antunes-Heck L; Division of Hematology & Oncology, Department of Pediatrics, School of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., Yu L; Division of Hematology, Department of Medicine, and., Brakhane M; Division of Hematology, Department of Medicine, and., Gao B; Division of Hematology & Oncology, Department of Pediatrics, School of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., Sykes SM; Division of Hematology & Oncology, Department of Pediatrics, School of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., D'Alessandro A; Department of Biochemistry and Molecular Genetics, University of Colorado-Anschutz Medical Campus, Aurora, Colorado, USA., Di Paola J; Division of Hematology & Oncology, Department of Pediatrics, School of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., Oh ST; Division of Hematology, Department of Medicine, and.; Immunomonitoring Laboratory, Center for Human Immunology and Immunotherapy Programs, and.; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.

المصدر: The Journal of clinical investigation [J Clin Invest] 2024 Feb 01; Vol. 134 (3). Date of Electronic Publication: 2024 Feb 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

مواضيع طبية MeSH: Neoplasms* , Myeloproliferative Disorders*/genetics , Myeloproliferative Disorders*/metabolism , Thrombocythemia, Essential*/genetics, Humans ; Mice ; Animals ; Multiomics ; Phosphatidylinositol 3-Kinases/genetics ; Proteomics ; Proto-Oncogene Proteins c-akt/genetics ; Inflammation ; TOR Serine-Threonine Kinases/genetics ; Adenosine Triphosphate ; Janus Kinase 2/genetics ; Mutation

المؤلفون: Fisher DAC; Division of Hematology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO., Laranjeira ABA; Division of Hematology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO., Kong T; Division of Hematology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO., Snyder SC; Division of Hematology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO., Shim K; Division of Hematology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO., Fulbright MC; Division of Hematology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO., Oh ST; Division of Hematology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO. Electronic address: stoh@wustl.edu.

المصدر: Experimental hematology [Exp Hematol] 2023 Dec; Vol. 128, pp. 48-66. Date of Electronic Publication: 2023 Aug 21.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Science Inc Country of Publication: Netherlands NLM ID: 0402313 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2399 (Electronic) Linking ISSN: 0301472X NLM ISO Abbreviation: Exp Hematol Subsets: MEDLINE

مواضيع طبية MeSH: Polycythemia Vera*/genetics , Myeloproliferative Disorders*/genetics , Myeloproliferative Disorders*/metabolism, Mice ; Humans ; Animals ; Janus Kinase 2/genetics ; Janus Kinase 2/metabolism ; Mutation ; Hematopoietic Stem Cells/metabolism ; Hematopoiesis/genetics ; Protein Serine-Threonine Kinases/genetics

المؤلفون: Kong T; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Laranjeira ABA; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Yang K; Department of Biochemistry, McGill University, Montreal, Quebec, Canada.; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada., Fisher DAC; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Yu L; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Poittevin De La Frégonnière L; Department of Biochemistry, McGill University, Montreal, Quebec, Canada.; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada., Wang AZ; Department of Neurological Surgery, Washington University School of Medicine, St. Louis, MO, USA., Ruzinova MB; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA., Fowles JS; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Fulbright MC; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Cox MJ; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Celik H; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Challen GA; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Huang S; Department of Biochemistry, McGill University, Montreal, Quebec, Canada.; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada., Oh ST; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA. stoh@wustl.edu.; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA. stoh@wustl.edu.; Immunomonitoring Laboratory, Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO, USA. stoh@wustl.edu.

المصدر: Nature cancer [Nat Cancer] 2023 Jan; Vol. 4 (1), pp. 108-127. Date of Electronic Publication: 2022 Dec 29.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-1347 (Electronic) Linking ISSN: 26621347 NLM ISO Abbreviation: Nat Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Myeloproliferative Disorders*/drug therapy , Myeloproliferative Disorders*/genetics , Myeloproliferative Disorders*/metabolism , Leukemia, Myeloid, Acute*/drug therapy , Leukemia, Myeloid, Acute*/genetics, Animals ; Mice ; Humans ; Signal Transduction/genetics ; Janus Kinases/metabolism ; Janus Kinase 2/genetics ; Janus Kinase 2/metabolism ; Dual Specificity Phosphatase 6/metabolism

المؤلفون: Kong T; Division of Hematology, Department of Medicine., Laranjeira ABA; Division of Hematology, Department of Medicine., Collins TB; Division of Hematology, Department of Medicine., De Togni ES; Division of Hematology, Department of Medicine., Wong AJ; Division of Hematology, Department of Medicine., Fulbright MC; Division of Hematology, Department of Medicine., Ruzinova M; Department of Pathology and Immunology, and., Celik H; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO; and., Challen GA; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO; and., Fisher DAC; Division of Hematology, Department of Medicine., Oh ST; Division of Hematology, Department of Medicine.; Department of Pathology and Immunology, and.; Immunomonitoring Laboratory, Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO.

المصدر: Blood advances [Blood Adv] 2022 Jan 25; Vol. 6 (2), pp. 611-623.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE

مواضيع طبية MeSH: Leukemia, Myeloid, Acute*/pathology , Myeloproliferative Disorders*/drug therapy , Myeloproliferative Disorders*/pathology , Primary Myelofibrosis*/pathology, Animals ; Cyclopentanes/therapeutic use ; Humans ; Mice ; Pyrimidines

المؤلفون: Fisher DAC; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Malkova O; Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO, USA., Engle EK; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Miner CA; Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO, USA., Fulbright MC; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Behbehani GK; Division of Hematology, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Collins TB; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Bandyopadhyay S; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Zhou A; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Nolan GP; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA., Oh ST; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.

المصدر: Leukemia [Leukemia] 2017 Sep; Vol. 31 (9), pp. 1962-1974. Date of Electronic Publication: 2016 Dec 23.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE

مواضيع طبية MeSH: Signal Transduction*, Leukemia, Myeloid, Acute/*metabolism , NF-kappa B/*metabolism , Primary Myelofibrosis/*metabolism, Antigens, CD34 ; Bone Marrow ; Cell Line ; Flow Cytometry/methods ; Humans ; Janus Kinase 2/genetics ; Leukemia, Myeloid, Acute/etiology ; Leukemia, Myeloid, Acute/pathology ; Primary Myelofibrosis/pathology