المؤلفون: Dymek B, Sklepkiewicz P, Mlacki M, Güner NC, Nejman-Gryz P, Drzewicka K, Przysucha N, Rymaszewska A, Paplinska-Goryca M, Zagozdzon A, Proboszcz M, Krzemiński Ł, von der Thüsen JH, Górska K, Dzwonek K, Zasłona Z, Dobrzanski P, Krenke R

المصدر: Journal of Inflammation Research, Vol Volume 15, Pp 5621-5634 (2022)

مصطلحات موضوعية: chitinase, oatd-01, granuloma, macrophages, interstitial lung disease, Pathology, RB1-214, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.dovepress.com/pharmacological-inhibition-of-chitotriosidase-chit1-as-a-novel-therape-peer-reviewed-fulltext-article-JIR; https://doaj.org/toc/1178-7031

URL الوصول: https://doaj.org/article/01cbe3adcdd046dbb0b3b76db82965b1

المؤلفون: Sklepkiewicz P; OncoArendi Therapeutics SA, 02-089, Warsaw, Poland., Dymek BA; OncoArendi Therapeutics SA, 02-089, Warsaw, Poland; Postgraduate School of Molecular Medicine, Medical University of Warsaw, 02-097, Warsaw, Poland. Electronic address: b.dymek@oncoarendi.com., Mlacki M; OncoArendi Therapeutics SA, 02-089, Warsaw, Poland., Koralewski R; OncoArendi Therapeutics SA, 02-089, Warsaw, Poland., Mazur M; OncoArendi Therapeutics SA, 02-089, Warsaw, Poland., Nejman-Gryz P; Department of Internal Medicine, Pulmonary Diseases and Allergy, Medical University of Warsaw, 02-097, Warsaw, Poland., Korur S; OncoArendi Therapeutics SA, 02-089, Warsaw, Poland., Zagozdzon A; OncoArendi Therapeutics SA, 02-089, Warsaw, Poland., Rymaszewska A; OncoArendi Therapeutics SA, 02-089, Warsaw, Poland., von der Thüsen JH; Department of Pathology, Erasmus Medical Center, 3015 GD, Rotterdam, the Netherlands., Siwińska AM; OncoArendi Therapeutics SA, 02-089, Warsaw, Poland., Güner NC; OncoArendi Therapeutics SA, 02-089, Warsaw, Poland., Cheda Ł; OncoArendi Therapeutics SA, 02-089, Warsaw, Poland., Paplinska-Goryca M; Department of Internal Medicine, Pulmonary Diseases and Allergy, Medical University of Warsaw, 02-097, Warsaw, Poland., Proboszcz M; Department of Internal Medicine, Pulmonary Diseases and Allergy, Medical University of Warsaw, 02-097, Warsaw, Poland., van den Bosch TPP; Department of Pathology, Erasmus Medical Center, 3015 GD, Rotterdam, the Netherlands., Górska K; Department of Internal Medicine, Pulmonary Diseases and Allergy, Medical University of Warsaw, 02-097, Warsaw, Poland., Golab J; Department of Immunology, Medical University of Warsaw, 02-097, Warsaw, Poland., Kamiński RM; OncoArendi Therapeutics SA, 02-089, Warsaw, Poland., Krenke R; Department of Internal Medicine, Pulmonary Diseases and Allergy, Medical University of Warsaw, 02-097, Warsaw, Poland., Golebiowski A; OncoArendi Therapeutics SA, 02-089, Warsaw, Poland., Dzwonek K; OncoArendi Therapeutics SA, 02-089, Warsaw, Poland., Dobrzanski P; OncoArendi Therapeutics SA, 02-089, Warsaw, Poland.

المصدر: European journal of pharmacology [Eur J Pharmacol] 2022 Mar 15; Vol. 919, pp. 174792. Date of Electronic Publication: 2022 Feb 02.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Hexosaminidases*/antagonists & inhibitors , Hexosaminidases*/metabolism , Idiopathic Pulmonary Fibrosis*/drug therapy , Idiopathic Pulmonary Fibrosis*/metabolism , Idiopathic Pulmonary Fibrosis*/pathology , Protein Kinase Inhibitors*/chemistry , Protein Kinase Inhibitors*/pharmacology , Protein Kinase Inhibitors*/therapeutic use, Adult ; Aged ; Aged, 80 and over ; Animals ; Female ; Humans ; Male ; Mice ; Middle Aged ; Young Adult ; Bleomycin ; Disease Models, Animal ; Mice, Inbred C57BL