المؤلفون: Kuo CY; Molecular and Cell Biology, Taiwan International Graduate Program, Academia Sinica and Graduate Institute of Life Science, National Defense Medical Center, Taipei, Taiwan.; Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan., Tay RJ; Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan., Lin HC; Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan., Juan SC; Molecular and Cell Biology, Taiwan International Graduate Program, Academia Sinica and Graduate Institute of Life Science, National Defense Medical Center, Taipei, Taiwan.; Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan., Vidal-Diez de Ulzurrun G; Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan., Chang YC; Department of Biochemistry and Molecular Cell Biology, College of Medicine, Taipei Medical University, Taipei, Taiwan., Hoki J; Boyce Thompson Institute, Cornell University, Ithaca, NY, USA.; Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY, USA., Schroeder FC; Boyce Thompson Institute, Cornell University, Ithaca, NY, USA.; Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY, USA., Hsueh YP; Molecular and Cell Biology, Taiwan International Graduate Program, Academia Sinica and Graduate Institute of Life Science, National Defense Medical Center, Taipei, Taiwan. pinghsueh@gate.sinica.edu.tw.; Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan. pinghsueh@gate.sinica.edu.tw.

المصدر: Nature microbiology [Nat Microbiol] 2024 Jul; Vol. 9 (7), pp. 1738-1751. Date of Electronic Publication: 2024 Apr 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101674869 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2058-5276 (Electronic) Linking ISSN: 20585276 NLM ISO Abbreviation: Nat Microbiol Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, G-Protein-Coupled*/metabolism , Receptors, G-Protein-Coupled*/genetics , Ascomycota*/metabolism , Ascomycota*/genetics , Ascomycota*/physiology , Pheromones*/metabolism, Animals ; Nematoda/microbiology ; Fungal Proteins/metabolism ; Fungal Proteins/genetics ; Signal Transduction ; Cyclic AMP-Dependent Protein Kinases/metabolism ; Cyclic AMP-Dependent Protein Kinases/genetics ; Caenorhabditis elegans/microbiology

SCR Organism: Arthrobotrys oligospora

المؤلفون: Patel K; Orphan Receptor Laboratory, School of Biomedical Sciences, Faculty of Medicine & Health, UNSW Sydney, Kensington, New South Wales, Australia., Smith NJ; Orphan Receptor Laboratory, School of Biomedical Sciences, Faculty of Medicine & Health, UNSW Sydney, Kensington, New South Wales, Australia.

المصدر: British journal of pharmacology [Br J Pharmacol] 2024 Jul; Vol. 181 (14), pp. 2182-2196. Date of Electronic Publication: 2023 Mar 04.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, G-Protein-Coupled*/metabolism , Cilia*/metabolism, Humans ; Animals ; A Kinase Anchor Proteins/metabolism ; Signal Transduction ; Hedgehog Proteins/metabolism

المؤلفون: Jiang L; Laboratory of Tropical Veterinary Medicine and Vector Biology, School of Life Sciences, Hainan University, Haikou, Hainan, China.; Hainan Province Key Laboratory of One Health, Collaborative Innovation Center of One Health, Hainan University, Haikou, Hainan, China., Xie XB; College of Life Sciences, Beijing Normal University, Beijing, China., Zhang L; Laboratory of Tropical Veterinary Medicine and Vector Biology, School of Life Sciences, Hainan University, Haikou, Hainan, China.; Hainan Province Key Laboratory of One Health, Collaborative Innovation Center of One Health, Hainan University, Haikou, Hainan, China.; Hainan International One Health Institute, Hainan University, Haikou, Hainan, China., Tang Y; Laboratory of Tropical Veterinary Medicine and Vector Biology, School of Life Sciences, Hainan University, Haikou, Hainan, China.; Hainan Province Key Laboratory of One Health, Collaborative Innovation Center of One Health, Hainan University, Haikou, Hainan, China., Zhu X; Laboratory of Tropical Veterinary Medicine and Vector Biology, School of Life Sciences, Hainan University, Haikou, Hainan, China.; Hainan Province Key Laboratory of One Health, Collaborative Innovation Center of One Health, Hainan University, Haikou, Hainan, China., Huang Y; Laboratory of Tropical Veterinary Medicine and Vector Biology, School of Life Sciences, Hainan University, Haikou, Hainan, China.; Hainan Province Key Laboratory of One Health, Collaborative Innovation Center of One Health, Hainan University, Haikou, Hainan, China., Hong Y; Hainan Province Key Laboratory of One Health, Collaborative Innovation Center of One Health, Hainan University, Haikou, Hainan, China., Hansson BS; Department of Evolutionary Neuroethology, Max Planck Institute for Chemical Ecology, Jena, Germany., Cui ZJ; College of Life Sciences, Beijing Normal University, Beijing, China., Han Q; Laboratory of Tropical Veterinary Medicine and Vector Biology, School of Life Sciences, Hainan University, Haikou, Hainan, China.; Hainan Province Key Laboratory of One Health, Collaborative Innovation Center of One Health, Hainan University, Haikou, Hainan, China.; Hainan International One Health Institute, Hainan University, Haikou, Hainan, China.

المصدر: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2024 Aug 15; Vol. 38 (15), pp. e23864.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE

مواضيع طبية MeSH: Aedes*/metabolism , Aedes*/genetics , Receptors, G-Protein-Coupled*/metabolism , Receptors, G-Protein-Coupled*/genetics, Animals ; Female ; CHO Cells ; Insect Proteins/metabolism ; Insect Proteins/genetics ; Cricetulus ; Feeding Behavior/physiology ; Mosquito Vectors

المؤلفون: Yang X; Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.; New Cornerstone Science Laboratory, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China., Zhou P; Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.; New Cornerstone Science Laboratory, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China., Shen S; Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China., Hu Q; Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.; New Cornerstone Science Laboratory, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China., Tian C; Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.; New Cornerstone Science Laboratory, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China., Xia A; Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.; Department of Ophthalmology and Research Laboratory of Macular Disease, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China., Wang Y; Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.; New Cornerstone Science Laboratory, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China., Yang Z; Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China., Nan J; Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China., Zhou Y; Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China., Chen S; Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China., Tian X; Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China., Wu C; Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China., Lin G; Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China., Zhang L; Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China., Wang K; Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China., Zheng T; Engineering Research Center of Medical Information Technology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China., Zou J; Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China., Yan W; Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China., Shao Z; Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.; Division of Nephrology and Kidney Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.; Frontier Medical Center, Tianfu Jincheng Laboratory, Chengdu, Sichuan 610212, China., Yang S; Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.; New Cornerstone Science Laboratory, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.; Frontier Medical Center, Tianfu Jincheng Laboratory, Chengdu, Sichuan 610212, China.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Jul 23; Vol. 121 (30), pp. e2401091121. Date of Electronic Publication: 2024 Jul 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Entropy* , Molecular Dynamics Simulation* , Receptors, G-Protein-Coupled*/metabolism , Receptors, G-Protein-Coupled*/chemistry, Ligands ; Animals ; Humans ; Protein Binding ; Mice ; Cryoelectron Microscopy ; Receptors, Cannabinoid/metabolism ; Receptors, Cannabinoid/chemistry ; Binding Sites

المؤلفون: McNeill SM; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Parkville, Melbourne, Victoria 3052, Australia., Lu J; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Parkville, Melbourne, Victoria 3052, Australia; ARC Centre for Cryo-Electron Microscopy of Membrane Proteins (CCeMMP), Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, Australia., Marion C Carino C; Graduate School of Pharmaceutical Sciences, Tokohu University, Sendai, Miyagi 980-8578, Japan., Inoue A; Graduate School of Pharmaceutical Sciences, Tokohu University, Sendai, Miyagi 980-8578, Japan., Zhao P; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Parkville, Melbourne, Victoria 3052, Australia; ARC Centre for Cryo-Electron Microscopy of Membrane Proteins (CCeMMP), Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, Australia., Sexton PM; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Parkville, Melbourne, Victoria 3052, Australia; ARC Centre for Cryo-Electron Microscopy of Membrane Proteins (CCeMMP), Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, Australia. Electronic address: patrick.sexton@monash.edu., Wootten D; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Parkville, Melbourne, Victoria 3052, Australia; ARC Centre for Cryo-Electron Microscopy of Membrane Proteins (CCeMMP), Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, Australia. Electronic address: denise.wootten@monash.edu.

المصدر: Biochemical pharmacology [Biochem Pharmacol] 2024 Apr; Vol. 222, pp. 116119. Date of Electronic Publication: 2024 Mar 08.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Diabetes Mellitus, Type 2* , G-Protein-Coupled Receptor Kinases*/genetics , G-Protein-Coupled Receptor Kinases*/metabolism, Humans ; Arrestins/genetics ; Arrestins/metabolism ; beta-Arrestin 1/metabolism ; beta-Arrestin 2/genetics ; beta-Arrestin 2/metabolism ; beta-Arrestins/metabolism ; Glucagon-Like Peptide-1 Receptor/metabolism ; HEK293 Cells ; Phosphorylation ; Receptors, G-Protein-Coupled/metabolism

المؤلفون: Batallán Burrowes AA; Center for Studies in Behavioral Neurobiology, Department of Psychology, Concordia University, Montreal, Québec, Canada., Moisan É; Center for Studies in Behavioral Neurobiology, Department of Psychology, Concordia University, Montreal, Québec, Canada., Garrone A; Center for Studies in Behavioral Neurobiology, Department of Psychology, Concordia University, Montreal, Québec, Canada., Buynack LM; Center for Studies in Behavioral Neurobiology, Department of Psychology, Concordia University, Montreal, Québec, Canada., Chapman CA; Center for Studies in Behavioral Neurobiology, Department of Psychology, Concordia University, Montreal, Québec, Canada.

المصدر: Hippocampus [Hippocampus] 2024 Sep; Vol. 34 (9), pp. 454-463. Date of Electronic Publication: 2024 Jun 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 9108167 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-1063 (Electronic) Linking ISSN: 10509631 NLM ISO Abbreviation: Hippocampus Subsets: MEDLINE

مواضيع طبية MeSH: Entorhinal Cortex*/drug effects , Entorhinal Cortex*/physiology , Receptors, G-Protein-Coupled*/metabolism , Estradiol*/pharmacology , Rats, Long-Evans* , Neurons*/drug effects , Neurons*/metabolism , Extracellular Signal-Regulated MAP Kinases*/metabolism, Animals ; Female ; Rats ; Inhibitory Postsynaptic Potentials/drug effects ; Inhibitory Postsynaptic Potentials/physiology ; Excitatory Postsynaptic Potentials/drug effects ; Excitatory Postsynaptic Potentials/physiology ; Receptors, Estrogen/metabolism ; Ovariectomy ; Synaptic Transmission/drug effects ; Synaptic Transmission/physiology ; Patch-Clamp Techniques ; Estrogens/pharmacology ; Cyclic AMP-Dependent Protein Kinases/metabolism ; Cyclic AMP-Dependent Protein Kinases/antagonists & inhibitors

المؤلفون: Zhang Y; State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530, China; University of Chinese Academy of Sciences, Beijing, 100049, China., Yu Z; State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530, China., Sun M; Basic Research Center, Bioland Laboratory, Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Guangzhou, 510530, China., Du R; State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530, China; University of Chinese Academy of Sciences, Beijing, 100049, China., Gao H; State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530, China; University of Chinese Academy of Sciences, Beijing, 100049, China., Dai Q; State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530, China; University of Chinese Academy of Sciences, Beijing, 100049, China., Dong Y; State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530, China; Guangdong Provincial Key Laboratory of Biocomputing, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530, China; China-New Zealand Joint Laboratory on Biomedicine and Health, Guangzhou, 510530, China., Liu C; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530, China., Yin M; State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530, China; University of Chinese Academy of Sciences, Beijing, 100049, China., Xu T; State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530, China; Guangdong Provincial Key Laboratory of Biocomputing, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530, China; China-New Zealand Joint Laboratory on Biomedicine and Health, Guangzhou, 510530, China., Zhang X; Basic Research Center, Bioland Laboratory, Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Guangzhou, 510530, China; CAS Key Laboratory of Regenerative Biology, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Center for Cell Lineage and Development, GIBH-HKU Guangdong-Hong Kong Stem Cell and Regenerative Medicine Research Centre, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, Guangdong, 510530, China., Liu J; State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530, China; University of Chinese Academy of Sciences, Beijing, 100049, China; Guangdong Provincial Key Laboratory of Biocomputing, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530, China; China-New Zealand Joint Laboratory on Biomedicine and Health, Guangzhou, 510530, China. Electronic address: liu_jinsong@gibh.ac.cn., Xu J; State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530, China; University of Chinese Academy of Sciences, Beijing, 100049, China; Guangdong Provincial Key Laboratory of Biocomputing, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530, China; China-New Zealand Joint Laboratory on Biomedicine and Health, Guangzhou, 510530, China. Electronic address: xu_jinxin@gibh.ac.cn.

المصدر: Redox biology [Redox Biol] 2024 Sep; Vol. 75, pp. 103253. Date of Electronic Publication: 2024 Jun 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier, B.V Country of Publication: Netherlands NLM ID: 101605639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2317 (Electronic) Linking ISSN: 22132317 NLM ISO Abbreviation: Redox Biol Subsets: MEDLINE

مواضيع طبية MeSH: Endosomes*/metabolism , Receptors, G-Protein-Coupled*/metabolism , Signal Transduction* , Sorting Nexins*/metabolism , Sorting Nexins*/genetics, Humans ; Oxidation-Reduction ; Protein Binding ; RGS Proteins/metabolism ; RGS Proteins/genetics

المؤلفون: Bernhard SM; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, USA.; Center for Clinical Pharmacology, University of Health Sciences & Pharmacy and Washington University School of Medicine, St. Louis, MO, USA., Han J; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, USA.; Center for Clinical Pharmacology, University of Health Sciences & Pharmacy and Washington University School of Medicine, St. Louis, MO, USA., Che T; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, USA.; Center for Clinical Pharmacology, University of Health Sciences & Pharmacy and Washington University School of Medicine, St. Louis, MO, USA.

المصدر: The FEBS journal [FEBS J] 2024 Jul; Vol. 291 (13), pp. 2784-2791. Date of Electronic Publication: 2024 Jan 08.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-4658 (Electronic) Linking ISSN: 1742464X NLM ISO Abbreviation: FEBS J Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, G-Protein-Coupled*/metabolism , Receptors, G-Protein-Coupled*/chemistry , Cryoelectron Microscopy* , Receptors, Opioid, kappa*/metabolism , Receptors, Opioid, kappa*/chemistry , Receptors, Opioid, kappa*/agonists , Receptors, Opioid, kappa*/genetics, Humans ; GTP-Binding Protein alpha Subunits, Gi-Go/metabolism ; GTP-Binding Protein alpha Subunits, Gi-Go/chemistry ; GTP-Binding Protein alpha Subunits, Gi-Go/genetics ; GTP-Binding Proteins/metabolism ; GTP-Binding Proteins/chemistry ; GTP-Binding Proteins/genetics ; Protein Binding ; Animals ; Protein Conformation ; Models, Molecular

المؤلفون: Trogdon M; Integrative Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA.; Pfizer, La Jolla, CA, 92037, USA., Abbott K; Department of Laboratory Medicine, Yale School of Medicine, New Haven, CT, 06520, USA., Arang N; Moores Cancer Center, University of California, San Diego, La Jolla, CA, 92093, USA.; Biomedical Sciences Graduate Program, University of California, San Diego, La Jolla, CA, 92093, USA., Lande K; Razavi Newman Integrative Genomics and Bioinformatics Core, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA., Kaur N; Department of Laboratory Medicine, Yale School of Medicine, New Haven, CT, 06520, USA., Tong M; Integrative Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA., Bakhoum M; Department of Ophthalmology and Visual Science, Yale School of Medicine, New Haven, CT, 06520, USA.; Yale Cancer Center, Yale School of Medicine, New Haven, CT, 06520, USA., Gutkind JS; Moores Cancer Center, University of California, San Diego, La Jolla, CA, 92093, USA.; Department of Pharmacology, University of California, San Diego, La Jolla, CA, 92093, USA., Stites EC; Department of Laboratory Medicine, Yale School of Medicine, New Haven, CT, 06520, USA. edward.stites@yale.edu.; Yale Cancer Center, Yale School of Medicine, New Haven, CT, 06520, USA. edward.stites@yale.edu.

المصدر: NPJ systems biology and applications [NPJ Syst Biol Appl] 2024 Jul 16; Vol. 10 (1), pp. 75. Date of Electronic Publication: 2024 Jul 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group in partnership with SBI, The Systems Biology Institute Country of Publication: England NLM ID: 101677786 Publication Model: Electronic Cited Medium: Internet ISSN: 2056-7189 (Electronic) Linking ISSN: 20567189 NLM ISO Abbreviation: NPJ Syst Biol Appl Subsets: MEDLINE

مواضيع طبية MeSH: Signal Transduction*/genetics , Signal Transduction*/physiology , Receptors, G-Protein-Coupled*/genetics , Receptors, G-Protein-Coupled*/metabolism , Mutation*/genetics, Humans ; Uveal Neoplasms/genetics ; Uveal Neoplasms/metabolism ; Systems Biology/methods ; Models, Biological ; Melanoma/genetics ; Melanoma/metabolism ; GTP-Binding Proteins/genetics ; GTP-Binding Proteins/metabolism

SCR Disease Name: Uveal melanoma

المؤلفون: Mukhaleva E; Department of Computational and Quantitative Medicine, Beckman Research Institute of the City of Hope, Duarte, California, USA; Irell and Manella Graduate School of Biological Sciences, Beckman Research Institute of the City of Hope, Duarte, California, USA., Ma N; Department of Computational and Quantitative Medicine, Beckman Research Institute of the City of Hope, Duarte, California, USA., van der Velden WJC; Department of Computational and Quantitative Medicine, Beckman Research Institute of the City of Hope, Duarte, California, USA., Gogoshin G; Department of Computational and Quantitative Medicine, Beckman Research Institute of the City of Hope, Duarte, California, USA., Branciamore S; Department of Computational and Quantitative Medicine, Beckman Research Institute of the City of Hope, Duarte, California, USA; Irell and Manella Graduate School of Biological Sciences, Beckman Research Institute of the City of Hope, Duarte, California, USA. Electronic address: SBranciamore@coh.org., Bhattacharya S; Department of Computational and Quantitative Medicine, Beckman Research Institute of the City of Hope, Duarte, California, USA. Electronic address: sbhattach@coh.org., Rodin AS; Department of Computational and Quantitative Medicine, Beckman Research Institute of the City of Hope, Duarte, California, USA; Irell and Manella Graduate School of Biological Sciences, Beckman Research Institute of the City of Hope, Duarte, California, USA. Electronic address: ARodin@coh.org., Vaidehi N; Department of Computational and Quantitative Medicine, Beckman Research Institute of the City of Hope, Duarte, California, USA; Irell and Manella Graduate School of Biological Sciences, Beckman Research Institute of the City of Hope, Duarte, California, USA. Electronic address: NVaidehi@coh.org.

المصدر: The Journal of biological chemistry [J Biol Chem] 2024 Jun; Vol. 300 (6), pp. 107362. Date of Electronic Publication: 2024 May 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Bayes Theorem* , Receptors, G-Protein-Coupled*/metabolism , Receptors, G-Protein-Coupled*/chemistry, Humans ; Molecular Dynamics Simulation ; Protein Binding ; GTP-Binding Protein alpha Subunits/metabolism ; GTP-Binding Protein alpha Subunits/chemistry ; GTP-Binding Protein alpha Subunits/genetics