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المؤلفون: Richard M. Angell, John Ludes-Meyers, Simon E. Ward, Michael Paradowski, Irina Chuckowree, Alexandre Bedernjak, James Lumley, Carol Villalonga Barber, Kenneth Powell, Edward Littler, Daniel Watterson, Geraldine Taylor, Elaine Thomas, Jose Gascon-Simorte, Mark E. Peeples, Michelle Thom, Jason S. McLellan, Dereck Tait, Neil Mathews, Paul R. Young, Ian M. Fraser, Morgan S.A. Gilman, James A. D. Good, G. Stuart Cockerill, Rachel Harland, Sara M. Johnson, Graham Lunn, Claire Scott, Gareth Williams
مصطلحات موضوعية: Biological Availability, Microbial Sensitivity Tests, Placebo, Antiviral Agents, 01 natural sciences, Virus, 03 medical and health sciences, Cell Line, Tumor, Drug Discovery, Animals, Humans, Respiratory system, IC50, 030304 developmental biology, Clinical Trials as Topic, 0303 health sciences, Drug discovery, Chemistry, Virus Internalization, Virology, 3. Good health, 0104 chemical sciences, Bioavailability, 010404 medicinal & biomolecular chemistry, Cell culture, Respiratory Syncytial Virus, Human, Molecular Medicine, Benzimidazoles, Viral Fusion Proteins, Viral load, Protein Binding
وصف الملف: application/pdf
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2
المؤلفون: Neil Mathews, G. Stuart Cockerill, James A. D. Good
المصدر: Journal of Medicinal Chemistry. 62:3206-3227
مصطلحات موضوعية: Palivizumab, viruses, Respiratory Syncytial Virus Infections, Antiviral Agents, 01 natural sciences, Viral infection, Virus, Small Molecule Libraries, 03 medical and health sciences, chemistry.chemical_compound, Viral life cycle, Drug Discovery, medicine, Animals, Humans, 030304 developmental biology, 0303 health sciences, Drug discovery, Ribavirin, Treatment options, Nucleocapsid Proteins, Virology, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry, Respiratory Syncytial Virus, Human, Molecular Medicine, Viral Fusion Proteins, Direct acting, medicine.drug
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المؤلفون: G. Stuart Cockerill
المصدر: Journal of medicinal chemistry. 63(15)
مصطلحات موضوعية: Indoles, Chemistry, viruses, Cell, Disease, Human physiology, Respiratory Syncytial Virus Infections, Crystallography, X-Ray, Imidazolidines, Fusion protein, Virology, Antiviral Agents, Virus, medicine.anatomical_structure, Treatment Outcome, Respiratory Syncytial Virus, Human, Drug Discovery, medicine, Molecular Medicine, Humans, In patient, Respiratory system, Clinical evaluation, Viral Fusion Protein Inhibitors
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4
المؤلفون: G. Stuart Cockerill, J. Jonathan Harburn
مصطلحات موضوعية: business.industry, medicine, Dengue virus, Current (fluid), medicine.disease_cause, business, Virology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::28c33155a4b8494abc014ff9a1ff11ec
https://doi.org/10.1201/9781351011655-4 -
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المؤلفون: G. Stuart Cockerill, Karen Elizabeth Lackey
مصطلحات موضوعية: Engineering, Process management, Drug discovery, business.industry, ERBB Family, Protein crystal structure, Normal tissue, Bioinformatics, Lapatinib, Clinical study, Knowledge base, medicine, Project management, business, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1445a2447990211d0d6b3c528ee64335
https://doi.org/10.1039/9781782621836-00676 -
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المؤلفون: Kimberly G. Petrov, Ann Louise Walker, Yu Guo, Malcolm Clive Carter, David W. Rusnak, Scott Howard Dickerson, Robert A. Mook, Cassandra A. Gauthier, Edgar R. Wood, Karen Lackey, G. Stuart Cockerill, Yue-Mei Zhang
المصدر: Bioorganic & Medicinal Chemistry Letters. 16:4686-4691
مصطلحات موضوعية: Models, Molecular, Receptor, ErbB-2, Clinical Biochemistry, Pharmaceutical Science, Lapatinib, Biochemistry, Inhibitory Concentration 50, Structure-Activity Relationship, ErbB, Cell Line, Tumor, Drug Discovery, medicine, Humans, Structure–activity relationship, Furans, skin and connective tissue diseases, Receptor, Protein Kinase Inhibitors, Molecular Biology, Molecular Structure, biology, Chemistry, Organic Chemistry, Enzyme assay, Cell biology, ErbB Receptors, Enzyme inhibitor, Quinazolines, biology.protein, Molecular Medicine, Signal transduction, Tyrosine kinase, medicine.drug
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المصدر: Tetrahedron Letters. 40:2601-2604
مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Stereochemistry, Aryl, Organic Chemistry, Drug Discovery, Biochemistry, Trifluoromethanesulfonate, Phosphonate, Stille reaction
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المؤلفون: Thierry Lequeux, Afshan H. Butt, Howard J. Easterfield, G. Stuart Cockerill, Kevin Blades, Jonathan M. Percy
المصدر: Journal of the Chemical Society, Perkin Transactions 1. :3609-3614
مصطلحات موضوعية: Dephosphorylation, chemistry.chemical_compound, Nitroaldol reaction, chemistry, Organic chemistry, Sulfoxide, Methylene, Hydrate, Phosphate, Nitroalkene, E1cB-elimination reaction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5ff82b642d19e281e16db6c04e7e0b91
https://doi.org/10.1039/a907052d -
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المصدر: ChemInform. 30
مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Aryl, General Medicine, Combinatorial chemistry, Phosphonate, Trifluoromethanesulfonate, Stille reaction
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المؤلفون: Kevin Blades, Afshan H. Butt, Howard J. Easterfield, Jonathan M. Percy, G. Stuart Cockerill, Thierry Lequeux
المصدر: ChemInform. 31
مصطلحات موضوعية: Elimination reaction, chemistry.chemical_compound, Nitroaldol reaction, Chemistry, Organic chemistry, Sulfoxide, General Medicine, Methylene, Nitroalkene, Phosphate, Hydrate, E1cB-elimination reaction