المؤلفون: Feng, Shu, Xie, Xingming, Li, Jianchao, Xu, Xu, Chen, Chaochun, Zou, Gaoliang, Lin, Guoyuan, Huang, Tao, Hu, Ruihan, Ran, Tao, Han, Lu, Zhang, Qingxiu, Li, Yuanqingxiao, Zhao, Xueke^{Aff1, IDs12072023106100_cor14}

المصدر: Hepatology International. 18(3):1040-1052

المؤلفون: Engin, Atilla^Aff8

المساهمون: Crusio, Wim E., Series Editor^Aff1, Dong, Haidong, Series Editor^Aff2, Radeke, Heinfried H., Series Editor^Aff3, Rezaei, Nima, Series Editor^Aff4, Xiao, Junjie, Series Editor^Aff5, Engin, Ayse Basak, editor^Aff6, Engin, Atilla, editor^Aff7

المصدر: Protein Kinase-mediated Decisions Between Life and Death. 1275:229-258

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المؤلفون: Tim Brecklinghaus, Wiebke Albrecht, Franziska Kappenberg, Julia Duda, Mian Zhang, Iain Gardner, Rosemarie Marchan, Ahmed Ghallab, Özlem Demirci Turgunbayer, Jörg Rahnenführer, Jan G. Hengstler

المساهمون: Dicle Üniversitesi, Fen Fakültesi, Biyoloji Bölümü, Turgunbayer, Özlem Demirci

مصطلحات موضوعية: Cholestasis, Chenodeoxycholic acid (CDCA), Cell Culture Techniques, General Medicine, Toxicology, Deoxycholic acid (DCA), Bile Acids and Salts, Hepatocytes, Humans, DILI, Glycochenodeoxycolic acid (GCDCA), Glycocholic acid (GCA), Cells, Cultured, Glycodeoxycholic acid (GDCA)

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7dd6f9a95b4b0670bdb61be1b168a6c
https://hdl.handle.net/11468/11744

المؤلفون: Grzych, Guillaume, Chavez-Talavera, Oscar, Descat, Amandine, Thuillier, Dorothee, Verrijken, An, Kouach, Mostafa, Legry, Vanessa, Verkindt, Helene, Raverdy, Violeta, Legendre, Benjamin, Caiazzo, Robert, Van Gaal, Luc, Goossens, Jean-Francois, Paumelle, Rejane, Francque, Sven, Pattou, Francois, Haas, Joel T., Tailleux, Anne, Staels, Bart

المساهمون: Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires - U1011 (RNMCD), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Groupe de Recherche sur les formes Injectables et les Technologies Associées - ULR 7365 (GRITA), Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Recherche translationnelle sur le diabète - U 1190 (RTD), University of Antwerp (UA), Antwerp University Hospital [Edegem] (UZA), ANR-16-RHUS-0006,PreciNASH,PreciNASH(2016), ANR-10-LABX-0046,EGID,EGID Diabetes Pole(2010), European Project: 694717,H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) ,ImmunoBile(2016), European Project: 32591,HEPADIP, European Project: 305707,EC:FP7:HEALTH,FP7-HEALTH-2012-INNOVATION-1,RESOLVE(2013), Derudas, Marie-Hélène, PreciNASH - - PreciNASH2016 - ANR-16-RHUS-0006 - RHUS - VALID, EGID Diabetes Pole - - EGID2010 - ANR-10-LABX-0046 - LABX - VALID, Bile acid, immune-metabolism, lipid and glucose homeostasis - ImmunoBile - - H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) 2016-09-01 - 2021-08-31 - 694717 - VALID, Hepatic and adipose tissue and functions in the metabolic syndrome - HEPADIP - 32591 - OLD, A systems biology approach to RESOLVE the molecular pathology of two hallmarks of patients with metabolic syndrome and its co-morbidities, hypertriglyceridemia and low HDL-cholesterol - RESOLVE - - EC:FP7:HEALTH2013-01-01 - 2017-12-31 - 305707 - VALID, Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires (RNMCD - U1011), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille

المصدر: JHEP Reports Innovation in Hepatology
JHEP Reports Innovation in Hepatology, 2021, 3 (2), pp.100222. ⟨10.1016/j.jhepr.2020.100222⟩
JHEP Reports Innovation in Hepatology, Elsevier, 2021, 3 (2), pp.100222. ⟨10.1016/j.jhepr.2020.100222⟩
JHEP Reports
JHEP Reports, Vol 3, Iss 2, Pp 100222-(2021)

مصطلحات موضوعية: GHDCA, glycolithocholic acid, taurohyodeoxycholic acid, OGTT, oral glucose tolerance test, GUDCA, glycoursodeoxycholic acid, TCDCA, FXR, farnesoid-X-receptor, UDCA, ADA, American Diabetes Association, IR, insulin resistance, GCA, glycocholic acid, THDCA, taurohyodeoxycholic acid, HCA, T2D, LCA, lithocholic acid, HCA, hyocholic acid, DCA, TCDCA, taurochenodeoxycholic acid, GCDCA, glycochenodeoxycholic acid, LCA, NASH, GCDCA, GHCA, glycohyocholic acid, TCA, cholic acid, [SDV] Life Sciences [q-bio], FPG, glycoursodeoxycholic acid, FXR, deoxycholic acid, glycocholic acid, non-alcoholic steatohepatitis, TDCA, taurodeoxycholic acid, HbA1c, NASH, non-alcoholic steatohepatitis, T2D, type 2 diabetes, Translational study, oral glucose tolerance test, digestive system, BA, UDCA, ursodeoxycholic acid, HDCA, glycochenodeoxycholic acid, TUDCA, tauroursodeoxycholic acid, NAFLD, OGTT, taurochenodeoxycholic acid, NAFL, non-alcoholic fatty liver, GCA, FPG, fasting plasma glycaemia, GDCA, glycodeoxycholic acid, GLCA, glycolithocholic acid, C4, bile acids, glycodeoxycholic acid, nutritional and metabolic diseases, HOMA2, homeostatic model assessment 2, hyocholic acid, digestive system diseases, farnesoid-X-receptor, DCA, deoxycholic acid, GUDCA, IR, TLCA, taurolithocholic acid, American Diabetes Association, CDCA, Human medicine, ABOS, Biological Atlas of Severe Obesity, HDCA, hyodeoxycholic acid, [SDV]Life Sciences [q-bio], HOMA2, taurodeoxycholic acid, taurolithocholic acid, C4, 7alpha-hydroxy-4-cholesten-3-one, insulin resistance, Biological Atlas of Severe Obesity, taurohyocholic acid, MAFLD, metabolic associated fatty liver disease, CA, cholic acid, CA, THCA, GHDCA, glycohyodeoxycholic acid, Diabetes, TLCA, glycohyocholic acid, ursodeoxycholic acid, TUDCA, TDCA, fasting plasma glycaemia, lithocholic acid, NAFL, BA, bile acids, chenodeoxycholic acid, non-alcoholic fatty liver, type 2 diabetes, ABOS, Research Article, NAFLD, non-alcoholic fatty liver disease, TCA, taurocholic acid, MAFLD, taurocholic acid, CDCA, chenodeoxycholic acid, metabolic associated fatty liver disease, glycated haemoglobin, homeostatic model assessment 2, Obesity, lcsh:RC799-869, tauroursodeoxycholic acid, 7alpha-hydroxy-4-cholesten-3-one, non-alcoholic fatty liver disease, THDCA, hyodeoxycholic acid, ADA, GDCA, lcsh:Diseases of the digestive system. Gastroenterology, HbA1c, glycated haemoglobin, GHCA, glycohyodeoxycholic acid, THCA, taurohyocholic acid, GLCA

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::74e69ecb4a62b415846d1ee012802a9c
https://www.hal.inserm.fr/inserm-03173334/document

المؤلفون: Veronika Voronova, Kirill Peskov, Victor Sokolov, Amani Al-Khaifi, Chanchal Kumar, Mats Rudling, Gabriel Helmlinger, Sara Straniero, Bo Angelin

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 1, Pp 149-170 (2020)
Cellular and Molecular Gastroenterology and Hepatology

مصطلحات موضوعية: 0301 basic medicine, Malabsorption, OATP, organic anion transporting polypeptide, Physiology-Based Modeling, Gallstones, uBA, unconjugated bile acid, Bile Acids, 0302 clinical medicine, Small intestinal bacterial overgrowth, Enterohepatic Circulation, FGF-19, fibroblast growth factor-19, Bile, Intestinal Mucosa, Enterohepatic circulation, tDCA, taurine-conjugated deoxycholic acid, Farnesoid X Receptor, Original Research, CA, cholic acid, Gastrointestinal tract, Cholesterol 7α-Hydroxylase, Bile acid, Chemistry, Liver Diseases, EHC, enterohepatic circulation, Gastroenterology, Gallbladder, gDCA, glycine-conjugated deoxycholic acid, uCA, unconjugated cholic acid, Editorial, Liver, BA, bile acid, CDCA, сhenodeoxycholic acid, 030211 gastroenterology & hepatology, uCDCA, unconjugated сhenodeoxycholic acid, Diarrhea, uDCA, unconjugated deoxycholic acid, medicine.medical_specialty, Biochemical Phenomena, medicine.drug_class, NTCP, sodium-taurocholate cotransporting polypeptide, Models, Biological, Permeability, Bile Acids and Salts, 03 medical and health sciences, FXR, farnesoid X receptor, Metabolic Diseases, Ileum, Internal medicine, gCA, glycine-conjugated cholic acid, tCDCA, taurine-conjugated сhenodeoxycholic acid, medicine, Humans, Fibroblast Growth Factor-19, lcsh:RC799-869, tCA, taurine-conjugated cholic acid, Hepatology, gCDCA, glycine-conjugated сhenodeoxycholic acid, Metabolism, CYP7A1, cholesterol 7α-hydroxylase, Lipid Metabolism, medicine.disease, ODE, ordinary differential equation, 030104 developmental biology, Endocrinology, DCA, deoxycholic acid, Intestinal Absorption, Farnesoid X receptor, lcsh:Diseases of the digestive system. Gastroenterology, ASBT, apical sodium-dependent bile acid transporter, Gastrointestinal Motility, Flux (metabolism)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99e7c1c53415ffd191bc13602d3d22bb
http://www.sciencedirect.com/science/article/pii/S2352345X20300266

المؤلفون: Petia Shipkova, Giridhar S. Tirucherai, Arun J. Sanyal, Diane E. Shevell, Benjamin E. Decato, Colleen A. McNaney, Yi Luo, Edgar D. Charles, Abraham Apfel

المصدر: JHEP Reports

مصطلحات موضوعية: GCDCA, glyco-chenodeoxycholic acid, C4, 7α-hydroxy-4-cholesten-3-one, Deoxycholic acid, FGF21, fibroblast growth factor 21, AST, aspartate aminotransferase, PGBF, pegbelfermin, Gastroenterology, chemistry.chemical_compound, FGF21, QD, once daily, Chenodeoxycholic acid, Nonalcoholic fatty liver disease, Immunology and Allergy, LCA, lithocholic acid, CA, cholic acid, Bile acid, LC, liquid chromatography, Fatty liver, baiH, 7β-hydroxy-3-oxo-delta4-cholenoic acid oxidoreductase, BA, bile acid, Research Article, TCDCA, tauro-chenodeoxycholic acid, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, medicine.drug_class, NASH, non-alcoholic steatohepatitis, TDCA, tauro-deoxycholic acid, hdhA, 7-alpha-hydroxysteroid dehydrogenase, GUDCA, glyco-ursodeoxycholic acid, Bile salt hydrolase, CYP7A1, cytochrome P450 7A1, PEGylated, polyethylene glycol-conjugated, UDCA, ursodeoxycholic acid, CDCA, chenodeoxycholic acid, FXR, farnesoid X receptor, TCA, tauro-cholic acid, Internal medicine, 7α-Hydroxy-4-cholesten-3-one, ALT, alanine aminotransferase, Internal Medicine, medicine, GCA, glyco-cholic acid, C4, Hepatology, business.industry, T2DM, type 2 diabetes mellitus, medicine.disease, GDCA, glyco-deoxycholic acid, QW, once weekly, chemistry, DCA, deoxycholic acid, MS, mass spectrometry, BSH, bile salt hydrolase, baiCD, 7α-hydroxy-3-oxo-delta4-cholenoic acid oxidoreductase, PRO-C3, N-terminal type III collagen propeptide, HbA1c, glycated haemoglobin, Microbiome, HFF, hepatic fat fraction, Steatosis, Steatohepatitis, business, ApoA1, apolipoprotein A1, Biomarkers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c523b47362c4cc87193b195c73edfb6d
https://pubmed.ncbi.nlm.nih.gov/34977519

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المؤلفون: Hsiao D. Lieu, Gideon M. Hirschfield, Arun J. Sanyal, Stephen A. Harrison, Lei Ling, Ulrich Beuers, Alex M. DePaoli

المساهمون: Gastroenterology and Hepatology, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism

المصدر: JHEP Reports
JHEP Reports, Vol 3, Iss 3, Pp 100255-(2021)
JHEP Reports, 3(3):100255. Elsevier

مصطلحات موضوعية: Fibroblast growth factor, RC799-869, AST, aspartate aminotransferase, chemistry.chemical_compound, Chenodeoxycholic acid, GCA, glycocholic acid, Immunology and Allergy, Bile acid synthesis, LCA, lithocholic acid, NASH CRN, NASH Clinical Research Network, Non-alcoholic steatohepatitis, TCDCA, taurochenodeoxycholic acid, CA, cholic acid, GCDCA, glycochenodeoxycholic acid, Bile acid, Primary sclerosing cholangitis, Deoxycholic acid, Gastroenterology, ELF test, Enhanced Liver Fibrosis test, Diseases of the digestive system. Gastroenterology, Ursodeoxycholic acid, FGF19, fibroblast growth factor 19, Glycodeoxycholic acid, G/T ratio, ratio of glycine to taurine conjugates of bile acids, NAS, non-alcoholic fatty liver disease activity score, BAAT, bile acid-CoA:amino acid N-acyltransferase, TDCA, taurodeoxycholic acid, medicine.drug, Research Article, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, medicine.drug_class, NASH, non-alcoholic steatohepatitis, TCA, taurocholic acid, Glycocholic acid, digestive system, Pro-C3, UDCA, ursodeoxycholic acid, CDCA, chenodeoxycholic acid, FXR, farnesoid X receptor, Internal medicine, ALT, alanine aminotransferase, Internal Medicine, medicine, MRI-PDFF, magnetic resonance imaging-proton density fat fraction, GDCA, glycodeoxycholic acid, GLCA, glycolithocholic acid, Hepatology, ALP, alkaline phosphatase, Cholic acid, FGF19, Fibrogenesis, Endocrinology, PSC, primary sclerosing cholangitis, chemistry, DCA, deoxycholic acid, Pro-C3, neoepitope-specific N-terminal pro-peptide of type III collagen, TLCA, taurolithocholic acid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba7001e197981d0d939e7dc5af50542f
https://pubmed.ncbi.nlm.nih.gov/33898959

المؤلفون: Jose J.G. Marin, Maria J. Monte, Malgorzata Milkiewicz, Miren Bravo, Fernando Lopitz-Otsoa, Javier Crespo, Carlos Ferre-Aracil, Sofia Lachiondo-Ortega, Virginia Gutiérrez-de-Juan, Marta Varela-Rey, Jose Luis Calleja, Teresa C. Delgado, María L. Martínez-Chantar, Mercedes Robles, Piotr Milkiewicz, Marina Serrano-Macia, Pablo Fernández-Tussy, Juan Anguita, Marcos López-Hoyos, Shelly C. Lu, David Fernández-Ramos, Naroa Goikoetxea-Usandizaga, Paula Iruzubieta, Natalia Elguezabal, Lucía Barbier-Torres, Jorge Simón, Mercedes Rincon

المساهمون: Universidad de Cantabria

المصدر: JHEP Reports, Vol 3, Iss 3, Pp 100276-(2021)
JHEP Reports Volume 3, Issue 3, June 2021, 100276
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
JHEP Reports

مصطلحات موضوعية: Mitochondrial ROS, MMP, mitochondrial membrane potential, LSM, liver stiffness, MPO, myeloperoxidase, AST, aspartate aminotransferase, Pgc1α, peroxisome proliferator-activated receptor gamma coactivator 1-alpha, RC799-869, Pharmacology, p-JNK, phosphor-JNK, TNF, tumour necrosis factor, Tfam, transcription factor A mitochondrial, Ccr5, C-C motif chemokine receptor 5, Immunology and Allergy, CLD, cholestatic liver disease, MLKL, mixed-lineage kinase domain-like pseudokinase, shRNA, small hairpin RNA, ANA, antinuclear antibodies, Hif-1α, hypoxia-inducible factor 1-alpha, Liver injury, GCDCA, glycochenodeoxycholic acid, Cholestasis, Bile acid, MCJ, methylation-controlled J, SDH2, succinate dehydrogenase, Gastroenterology, α-SMA, alpha-smooth muscle actin, Pgc1β, peroxisome proliferator-activated receptor gamma coactivator 1-beta, ROS, Bile duct ligation, Diseases of the digestive system. Gastroenterology, Mitochondria, Ccr2, C-C motif chemokine receptor 2, Ezh2, enhancer of zeste homolog 2, Mitochondrial respiratory chain, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, JNK, c-Jun N-terminal kinase, BA, bile acid, BAX, BCL2 associated X, RT, room temperature, VCTE, vibration-controlled transient elastography, HSC, hepatic stellate cells, Research Article, PARP, poly (ADP-ribose) polymerase, Cxcl1, C-X-C motif chemokine ligand 1, p-MLKL, phosphor-MLKL, medicine.drug_class, mRNA, messenger ribonucleic acid, ETC, electron transport chain, Nrf1, nuclear respiratory factor 1, APRI, AST to platelet ratio index, BDL, bile duct ligation, Ccl2, C-C motif chemokine ligand 2, MPT, mitochondrial permeability transition, UDCA, ursodeoxycholic acid, Primary sclerosing cholangitis, AMA-M2, antimitochondrial M2 antibody, ROS, reactive oxygen species, BCL-Xl, B-cell lymphoma-extra large, ALT, alanine aminotransferase, Internal Medicine, medicine, Trail, TNF-related apoptosis-inducing ligand, tBIL, total bilirubin, KO, knockout, ALP, alkaline phosphatase, Hepatology, business.industry, medicine.disease, WT, wild-type, MCJ, PSC, primary sclerosing cholangitis, DCA, deoxycholic acid, Mitochondrial permeability transition pore, siRNA, small interfering RNA, Ucp2, uncoupling protein 2, Fxr, farnesoid X receptor, Hepatic stellate cell, PBC, primary biliary cholangitis, business, Cyp7α1, cholesterol 7 alpha-hydroxylase, BCL-2, B-cell lymphoma 2, MAPK, mitogen-activated protein kinase, Abs, antibodies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::260a6a78478feb3a4a8f609b4afaa257
https://pubmed.ncbi.nlm.nih.gov/33997750