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المؤلفون: Hai-Yong Chen, Yibin Feng, Cheng Zhang, Ning Wang, Sha Li, Guoyi Tang
المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2749-2767 (2021)مصطلحات موضوعية: LOX1, lectin-like oxidized LDL receptor 1, BUN, blood urea nitrogen, TGBM, thickness of glomerular basement membrane, NQO1, NAD(P)H:quinone oxidoreductase 1, STAT, signal transducers and activators of transcription, N/O, not observed, p62, sequestosome 1 protein, p-IRS1, phospho-IRS1, Review, NOX-4, nicotinamide adenine dinucleotide phosphate-oxidase-4, OCP, oxidative carbonyl protein, Traditional Chinese medicine, AGEs, advanced glycation end-products, N/A, not applicable, TRAF5, tumor-necrosis factor receptor-associated factor 5, Health problems, 0302 clinical medicine, ESRD, end-stage renal disease, LDL, low-density lipoprotein, BMP-7, bone morphogenetic protein-7, TGFβR-I/II, TGF-β receptor I/II, Medicine, P70S6K, 70-kDa ribosomal protein S6 kinase, General Pharmacology, Toxicology and Pharmaceutics, SOCS, suppressor of cytokine signaling proteins, HO-1, heme oxygenase-1, 0303 health sciences, TG, triglyceride, BW, body weight, HDL-C, high density lipoprotein-cholesterol, RASI, renin-angiotensin system inhibitor, ATK, protein kinase B, TBARS, thiobarbituric acid-reactive substance, BCL-XL, B-cell lymphoma-extra large, Gαq, Gq protein alpha subunit, GCK, glucokinase, PI3K, phosphatidylinositol 3 kinases, Systematic review, TLR-2/4, toll-like receptor 2/4, IR, insulin receptor, PERK, protein kinase RNA-like eukaryotic initiation factor 2A kinase, 030220 oncology & carcinogenesis, CRP, C-reactive protein, IRS, insulin receptor substrate, AM, mesangial area, JAK, Janus kinase, FBG, fasting blood glucose, ETAR, endothelium A receptor, LDL-C, low density lipoprotein-cholesterol, CD2AP, CD2-associated protein, eIF2α, eukaryotic initiation factor 2α, RM1-950, mTOR, mammalian target of rapamycin, CHOP, C/EBP homologous protein, STZ, streptozotocin, 03 medical and health sciences, ADE, adverse event, PKC, protein kinase C, LC3, microtubule-associated protein light chain 3, ORP150, 150-kDa oxygen-regulated protein, PGE2, prostaglandin E2, IL-1β/6, interleukin 1β/6, Diabetic kidney disease, IGF-1, insulin-like growth factor 1, EP, E-prostanoid receptor, FN, fibronectin, eGFR, estimated GFR, MDA, malondialdehyde, Chinese medicine, MMP-2, matrix metallopeptidase 2, XBP-1, spliced X box-binding protein 1, TGF-β, tumor growth factor β, GRB 10, growth factor receptor-bound protein 10, medicine.disease, Clinical trial, GRP78, glucose-regulated protein 78, UP, urinary protein, IGF-1R, insulin-like growth factor 1 receptor, ACEI, angiotensin-converting enzyme inhibitor, BCL-2, B-cell lymphoma 2, EMT, epithelial-to-mesenchymal transition, MAPK, mitogen-activated protein kinase, MYD88, myeloid differentiation primary response 88, PBG, postprandial blood glucose, RCT, randomized clinical trial, N/R, not reported, COL-I/IV, collagen I/IV, PINK1, PTEN-induced putative kinase 1, UACR, urinary albumin to creatinine ratio, C, control group, Diabetic nephropathy, GPX, glutathione peroxidase, ICAM-1, intercellular adhesion molecule-1, Bioinformatics, VCAM-1, vascular cell adhesion molecule-1, AMPKα, adenosine monophosphate-activated protein kinase α, DM, diabetes mellitus, TFEB, transcription factor EB, TNF-α, tumor necrosis factor α, Molecular target, IKK-β, IκB kinase β, Signaling pathway, GLUT4, glucose transporter type 4, BAX, BCL-2-associated X protein, NF-κB, nuclear factor kappa-light-chain-enhancer of activated B cells, PARP, poly(ADP-Ribose) polymerase, SMURF-2, SMAD ubiquitination regulatory factor 2, AREs, antioxidant response elements, MD, mean difference, SMAD, small mothers against decapentaplegic, MCP-1, monocyte chemotactic protein-1, VEGF, vascular endothelial growth factor, cAMP, cyclic adenosine monophosphate, ARB, angiotensin receptor blocker, PAI-1, plasminogen activator inhibitor-1, SMD, standard mean difference, JNK, c-Jun N-terminal kinase, NRF2, nuclear factor erythroid 2-related factor 2, IκB-α, inhibitory protein α, Herbal medicine, TCM, traditional Chinese medicine, DG, glomerular diameter, GSK-3, glycogen synthase kinase 3, SIRT1, sirtuin 1, D, duration, HbA1c, glycosylated hemoglobin, WMD, weight mean difference, CTGF, connective tissue growth factor, ER, endoplasmic reticulum, DN, diabetic nephropathy, ROS, reactive oxygen species, CCR, creatinine clearance rate, SOD, superoxide dismutase, Diabetes mellitus, PGC-1α, peroxisome proliferator-activated receptor gamma coactivator 1α, ET-1, endothelin-1, UMA, urinary microalbumin, SCr, serum creatinine, IRE-1α, inositol-requiring enzyme-1α, 030304 developmental biology, TII, tubulointerstitial injury index, RAGE, receptors of AGE, business.industry, GFR, glomerular filtration rate, PTEN, phosphatase and tensin homolog, CI, confidence interval, TC, total cholesterol, SD-rat, Sprague–Dawley rat, UAER, urinary albumin excretion rate, DKD, diabetic kidney disease, T, treatment group, Molecular targets, Therapeutics. Pharmacology, α-SMA, α smooth muscle actin, SD, standard deviation, business, DAG, diacylglycerol, GCLC, glutamate-cysteine ligase catalytic subunit, Kidney disease
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المؤلفون: Bo Kong, Christina Ferrucci Da Silva, Lucy Lu, Thomas Hegyi, Naureen Memon, Michael J. Campbell, Le Zhan, Grace L. Guo, Jianliang Shen
المصدر: Acta Pharmaceutica Sinica B, Vol 10, Iss 1, Pp 153-158 (2020)
Acta Pharmaceutica Sinica. Bمصطلحات موضوعية: Original article, medicine.medical_specialty, Total parenteral nutrition, Parenteral nutrition-associated liver disease, Ho-1, heme oxygenase 1, 03 medical and health sciences, Liver disease, chemistry.chemical_compound, GSTP1, Mt-1, metallothionein 1, ROS, reactive oxygen species, 0302 clinical medicine, Internal medicine, Gene expression, GSH, glutathione, NQO1, NAD(P)H:quinone acceptor oxidoreductase 1, medicine, Gstm3, glutathione S-transferase, mu 3, Gstm6, glutathione S-transferase, mu 6, Gstm1, glutathione S-transferase, mu 1, General Pharmacology, Toxicology and Pharmaceutics, 030304 developmental biology, Drug metabolism, Gpx3, glutathione peroxidase 3, TPN, total parenteral nutrition, 0303 health sciences, GADPH, glyceraldehyde 3-phosphate dehydrogenase, GCLM, business.industry, CYP450, cytochrome p450, lcsh:RM1-950, Gclc: glutamate-cysteine ligase catalytic subunit, Gclm: glutamate-cysteine ligase modifier subunit, Glutathione, FAs, fatty acids, medicine.disease, 3. Good health, Gstp1, glutathione S-transferase, pi 1, lcsh:Therapeutics. Pharmacology, GCLC, Parenteral nutrition, Endocrinology, Liver, chemistry, 030220 oncology & carcinogenesis, GSSG, GSH/glutathione disulfide, PNALD, parenteral nutrition-associated liver disease, business
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المؤلفون: James E. Goldman, Alice Tang, Michelle L. Olsen, Natasha L. Pacheco, Jiangtao Li, Daniel Flint, Brett S. Phinney, Anthony W. Herren, Fatima Khan, Michael R. Heaven
المصدر: Molecular & cellular proteomics : MCP, vol 21, iss 1
Molecular & Cellular Proteomics : MCPمصطلحات موضوعية: Proteomics, Cnp, 2′,3′-cyclic-nucleotide 3′-phosphodiesterase, Nadk2, NAD kinase 2, mitochondrial, Pck2, phosphoenolpyruvate carboxykinase [GTP], mitochondrial, Slc16a1, monocarboxylate transporter 1, PPAR, peroxisome proliferator-activated receptor, Mog, myelin-oligodendrocyte glycoprotein, Nfe2l2, nuclear factor erythroid 2-related factor 2, Mlc1, membrane protein MLC1, Biochemistry, C1qc, complement C1q subcomponent subunit C, Transgenic, Analytical Chemistry, Acadl, Long-chain specific acyl-CoA dehydrogenase, mitochondrial, Myelin, Mice, Gsr, glutathione reductase, mitochondrial, Cryl1, lambda-crystallin homolog, Sqstm1, sequestosome-1, BCA, bicinchoninic acid assay, LC3, microtubule-associated protein 1A/1B-light chain 3, Gliosis, SRM, selected reaction monitoring, Aetiology, Gclm, glutamate--cysteine ligase regulatory subunit, μDIA, micro-data-independent acquisition, Acsl3, long-chain-fatty-acid--CoA ligase 3, Cat, catalase, Acot2, Acyl-coenzyme A thioesterase 2, Glial fibrillary acidic protein, Rps27a, ubiquitin-40S ribosomal protein S27a, Acsl6, long-chain-fatty-acid--CoA ligase 6, Aldh1l1, Cytosolic 10-formyltetrahydrofolate dehydrogenase, Slc25a18, mitochondrial glutamate carrier 2, Bsn, protein bassoon, Fabp7, fatty acid binding protein, brain, Plp1, myelin proteolipid protein, Gsta3, glutathione S-transferase A3, Prdx6, peroxiredoxin-6, Alexander Disease, Slc6a11, sodium- and chloride-dependent GABA transporter 3, Ccnd2, G1/S-specific cyclin-D2, Stxbp5l, syntaxin-binding protein 5-like, GAPDH, glyceraldehyde 3 phosphate dehydrogenase, Slc6a17, sodium-dependent neutral amino acid transporter SLC6A17, Biochemistry & Molecular Biology, Ilk, integrin-linked protein kinase, Kcnj10, ATP-sensitive inward rectifier potassium channel 10, Ugt8, Gan, gigaxonin, Ttyh1, protein tweety homolog 1, Hsp27, heat shock protein beta-1, TBI, traumatic brain injury, reactive gliosis, Hmgcs2, hydroxymethylglutaryl-CoA synthase, mitochondrial, Idh2, isocitrate dehydrogenase [NADP], mitochondrial, KEGG, Kyoto encyclopedia of genes and genomes, Genetics, Humans, Gpr37l1, prosaposin receptor GPR37L1, Molecular Biology, Txnrd1, thioredoxin reductase 1, cytoplasmic, Slc38a3, sodium-coupled neutral amino acid transporter 3, Animal, DAVID, database for annotation, visualization and integrated discovery, GFAP, glial fibrillary acidic protein, astrocytes, Rack1, receptor of activated protein C kinase 1, Ugt8, 2-hydroxyacylsphingosine 1-beta-galactosyltransferase, Apoa1, apolipoprotein A-I, medicine.disease, Oligodendrocyte, GABA, gamma aminobutyric acid, Slc27a1, long-chain fatty acid transport protein 1, nervous system, Fabp7, Mutation, Mag, myelin-associated glycoprotein, Gclc, glutamate--cysteine ligase catalytic subunit, Gsto1, glutathione S-transferase omega-1, Ephx1, epoxide hydrolase 1, Gpx1, glutathione peroxidase 1, C1qa, complement C1q subcomponent subunit A, MDD, major depressive disorder, Cd44, Cd44 antigen, Slc4a4, electrogenic sodium bicarbonate cotransporter 1, Neurodegenerative, Dlg4, disks large homolog 4, TIC, total ion current, Gstm1, glutathione S-transferase Mu 1, Alexander disease, 2.1 Biological and endogenous factors, Functional ability, Ndrg2, protein NDRG2, Sfxn5, sideroflexin-5, Ca2, carbonic anhydrase 2, S1pr1, sphingosine 1-phosphate receptor 1, Gpx3, glutathione peroxidase 3, Snap25, synaptosomal-associated protein 25, Sparcl1, SPARC-like protein 1, medicine.diagnostic_test, Prdx1, peroxiredoxin-1, medicine.anatomical_structure, Neurological, Pgd, 6-phosphogluconate dehydrogenase, decarboxylating, Mbp, myelin basic protein, LPA, lysophosphatidic acid, Astrocyte, Gss, glutathione synthetase, Stat3, signal transducer and activator of transcription 3, Biotechnology, Sorbs1, Sorbin and SH3 domain-containing protein 1, RFs, Rosenthal fibers, Pygb, glycogen phosphorylase, brain form, Ctsd, cathepsin D, Ddx3x, ATP-dependent RNA helicase DDX3X, Fasn, fatty acid synthase, Slc1a2, excitatory amino acid transporter 2, PPP, pentose phosphate pathway, Mice, Transgenic, Plpp3, phospholipid phosphatase 3, Biology, C1qb, complement C1q subcomponent subunit B, CNS, central nervous system, Gja1, gap junction alpha-1 protein, PRM-MS, parallel reaction monitoring-mass spectrometry, TFA, trifluoro acetic acid, Vim, vimentin, Rare Diseases, Western blot, Downregulation and upregulation, Acox1, peroxisomal acyl-coenzyme A oxidase 1, Mobp, myelin-associated oligodendrocyte basic protein, medicine, Atp1b2, sodium/potassium-transporting ATPase subunit beta-2, Animals, Cryab, alpha-crystallin B chain, MS2, MS/MS or tandem mass spectrometry, Research, Neurosciences, Molecular biology, Ntrk2, BDNF/NT-3 growth factors receptor, Brain Disorders, AxD, Alexander disease, Disease Models, Animal, Acox3, Peroxisomal acyl-coenzyme A oxidase 3, Disease Models, biology.protein, Ugp2, UTP--glucose-1-phosphate uridylyl transferase, Acot1, Acyl-coenzyme A thioesterase 1
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27db73f1a1ae5cb5705d0a860adbda89
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المؤلفون: Wen-Xing Ding, Hartmut Jaeschke, David S Umbaugh, Olamide B. Adelusi, Giselle Sanchez-Guerrero, Nga T. Nguyen, Jephte Y. Akakpo, Anup Ramachandran
المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3740-3755 (2021)مصطلحات موضوعية: GSSG, glutathione disulfide, LOOH, lipid hydroperoxides, NQO1, NAD(P)H:quinone oxidoreductase 1, TLR, toll like receptor, HNE, 4-hydroxynonenal, NAC, N-acetylcysteine, Apoptosis, Review, Bioinformatics, SMAC/DIABLO, second mitochondria-derived activator of caspase/direct inhibitor of apoptosis-binding protein with low pI, GSH, glutathione, General Pharmacology, Toxicology and Pharmaceutics, Liver injury, Innate immunity, BSO, buthionine sulfoximine, mTORC1, mammalian target of rapamycin complex 1, MCP-1, monocyte chemoattractant protein-1, Mitochondria, CYP, cytochrome P450 enzymes, GPX4, glutathione peroxidase 4, NRF2, nuclear factor erythroid 2-related factor 2, KEAP1, Kelch-like ECH-associated protein 1, LPO, lipid peroxidation, NF-κB, nuclear factor κB, medicine.drug, DMSO, dimethylsulfoxide, Inflammatory response, Gclm, glutamate–cysteine ligase modifier subunit, HMGB1, high mobility group box protein 1, APAP, acetaminophen, ARE, antioxidant response element, RM1-950, TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling, UGT, UDP-glucuronosyltransferases, Necrotic cell, MPT, mitochondrial permeability transition, Acetaminophen hepatotoxicity, NRF2, ROS, reactive oxygen species, EndoG, endonuclease G, medicine, Autophagy, Injury mechanisms, Ferroptosis, MnSOD, manganese superoxide dismutase, Antipyretic drugs, MDA, malondialdehyde, Drug metabolism, business.industry, ATG, autophagy-related genes, PUFAs, polyunsaturated fatty acids, Liver failure, medicine.disease, CAD, caspase-activated DNase, Gclc, glutamate–cysteine ligase catalytic subunit, Acetaminophen, LC3, light chain 3, AIF, apoptosis-inducing factor, AMPK, AMP-activated protein kinase, DAMPs, damage-associated molecular patterns, JNK, c-jun N-terminal kinase, Therapeutics. Pharmacology, LAMP, lysosomal-associated membrane protein, business, NAPQI, N-acetyl-p-benzoquinone imine, FSP1, ferroptosis suppressing protein 1, MAP kinase, mitogen activated protein kinase
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المؤلفون: Edward Moreira Bahnson, Wulin Jiang, Nicholas Buglak
المصدر: Redox Biology, Vol 19, Iss, Pp 166-178 (2018)
Redox Biologyمصطلحات موضوعية: 0301 basic medicine, Male, Vascular smooth muscle, ZDF, Zucker Diabetic Fatty rat, Clinical Biochemistry, Cell, MPO, myeloperoxidase, 030204 cardiovascular system & hematology, Biochemistry, Nrf2, nuclear factor erythroid 2-related factor 2, Antioxidants, Muscle, Smooth, Vascular, BrdU, bromodeoxyuridine, 0302 clinical medicine, Restenosis, DM, diabetes mellitus, I:M, intima:media, GSH, glutathione, ARE/EpRE, antioxidant/electrophile response element, Acrolein, lcsh:QH301-705.5, Cells, Cultured, HO-1, heme oxygenase-1, SFN, sulforaphane, Neointimal hyperplasia, chemistry.chemical_classification, NOX1, NADPH oxidase 1, lcsh:R5-920, Diabetes, 3. Good health, CA, cinnamic aldehyde, medicine.anatomical_structure, VSMC, vascular smooth muscle cells, lcsh:Medicine (General), Artery, Research Paper, medicine.medical_specialty, PDGF, platelet derived growth factor, NF-E2-Related Factor 2, Cinnamic aldehyde, CVD, cardiovascular disease, Nrf2, Diabetes Complications, 03 medical and health sciences, ROS, reactive oxygen species, In vivo, Internal medicine, Neointima, SOD, superoxide dismutase, medicine, Diabetes Mellitus, Vascular smooth muscle cells, Animals, Cell Proliferation, Reactive oxygen species, XO, xanthine oxidase, Hyperplasia, Cell growth, business.industry, Organic Chemistry, medicine.disease, Rats, Zucker, 030104 developmental biology, Endocrinology, chemistry, lcsh:Biology (General), Prx, peroxiredoxin, business, Tunica Intima, DHE, dihydroethidium, GCLC, glutamate-cysteine ligase catalytic subunit
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المؤلفون: Jing Li, Shuang Li, Chaohua Tang, Tengfei Zhan, Qingyu Zhao, Kai Zhang, Xiaoqing Guo, Junmin Zhang, Yunsheng Han
المصدر: Redox Biology
Redox Biology, Vol 36, Iss, Pp 101519-(2020)مصطلحات موضوعية: ACAA2, 3-ketoacyl-CoA thiolase mitochondrial, Swine, IL1R1, IL-1β receptor, PLCG2, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2, Biochemistry, 0302 clinical medicine, Selenium deficiency, ceRNA, competing endogenous RNA, GSH, glutathione, Glycolysis, ANPEP, aminopeptidase N, KLF15, krueppel-like factor 15, lcsh:QH301-705.5, GSSG, oxidized glutathione, SAM, S-adenosylmethionine, TG, triglycerides, PS, phosphatidylserine, Warburg effect, TGF-β, transfer growth factor β, Se-D, Se deficient, Sed-7p, sedoheptulose 7-phosphate, PDK4, pyruvate dehydrogenase kinase isozyme 4, PLPP3, phosphatidate phosphatase 3, PKLR, pyruvate kinase, lcsh:Medicine (General), Redox imbalance, PE, phosphatidylethanolamine, ICP-MS, inductively coupled plasma mass spectrometry, 03 medical and health sciences, Selenium, NADH, nicotinamide adenine dinucleotide, Se-A, Se adequate, CPT2, carnitine palmitoyltransferase 2, NF-κB, nuclear factor κ-light-chain-enhancer’ of activated B-cells, MDA, malondialdehyde, PGD, 6-phosphogluconate dehydrogenase, PAPSS2, bifunctional 3′-phosphoadenosine5′-phosphosulfate synthase 2, ISG15, ubiquitin-like protein ISG15, medicine.disease, IL, interleukin, Citric acid cycle, 030104 developmental biology, TKFC, dihydroxyacetone kinase, SELENO, selenoprotein, Diabetes Mellitus, Type 2, ACOX1, acyl-CoA oxidase 1, CAT, catalase, DGKZ, diacylglycerol kinase zeta, 030217 neurology & neurosurgery, 0301 basic medicine, ACSL5, long-chain-fatty-acid--CoA ligase 5-like, Clinical Biochemistry, FASN, fatty acid synthase, SEPHS2, selenophosphate synthetase 2, GPX, glutathione peroxidase, PG, phosphatidylglycerol, GST, glutathione S-transferase, GK, glycerol kinase, PC, phosphatidylcholine, TXNRD, thioredoxin reductase, TNF-α, tumor necrosis factor α, MSRB, methionine-R-sulfoxide, lcsh:R5-920, ncRNA, non-coding RNA, RIG-1, antiviral innate immune response receptor RIG-I, Chemistry, Metabolic reprogramming, TRX, thioredoxin, Liver, Ribu-5P, ribose-5-phosphate, GPAM, glycerol-3-phosphate acyltransferase 1, Oxidation-Reduction, TCA, tricarboxylic acid cycle, DG, diglycerides, Research Paper, SOD, super oxide dismutase, ATP, adenosine triphosphate, CL, cardiolipin, Mx1, interferon-induced GTP-binding protein Mx1, PPP, pentose phosphate pathway, Cysthi, l-Cystathionine, PI, phosphatidylinositol, Se, selenium, ROS, reactive oxygen species, IFIT, interferon-induced protein with tetratricopeptide repeats, medicine, Metabolome, Animals, Cer, ceramides, Inflammation, PCA, principal component analysis, 2-OG, Oxoglutaric acid, Catabolism, Organic Chemistry, SAH, S-adenosylhomocysteine, Lipid metabolism, NADPH, nicotinamide adenine dinucleotide phosphate, ADP, adenosine diphosphate, GLUD1, glutamate dehydrogenase 1, Glutamine, AMPK, AMP-activated protein kinase, lcsh:Biology (General), AMP, adenosine monophosphate, FA, fatty acids, CPT1A, carnitine O-palmitoyltransferase 1, HIF-1α, hypoxia-inducible factor 1α, Pig liver, CTH, cystathionase, GCLC, glutamate-cysteine ligase catalytic subunit
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المؤلفون: Ana M. Tormos, Sergio Rius-Pérez, Angel R. Nebreda, Juan Sastre, Raquel Taléns-Visconti, Isabela Finamor, Salvador Pérez
المصدر: Redox Biology, Vol 16, Iss, Pp 276-284 (2018)
Redox Biologyمصطلحات موضوعية: ROS, Reactive oxygen species, RSK1, Ribosomal S6 kinase1, 0301 basic medicine, MAPK/ERK pathway, Aging, HPLC, High-performance liquid chromatography, Antioxidant, medicine.medical_treatment, TBP, TATA-binding protein, Clinical Biochemistry, DEN, Diethyl nitrosamine, MKP-1, MAPK phosphatase-1, IκB kinase, GCLc, Glutamate cysteine ligase catalytic subunit, p38 Mitogen-Activated Protein Kinases, G6PDH, Glucose-6-phosphate dehydrogenase, Biochemistry, Antioxidants, Mice, chemistry.chemical_compound, Superoxide Dismutase-1, Akt, Protein kinase B, 0302 clinical medicine, Nrf2, Nuclear factor erythroid 2-related factor-2, IL, Interleukin, SOD1, Cu/Zn-superoxide dismutase, lcsh:QH301-705.5, Mice, Knockout, MK2, MAP-activated protein kinase 2, PGC-1α, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, chemistry.chemical_classification, lcsh:R5-920, Trx, Thioredoxin, Glutathione Disulfide, TNF-α, Tumor necrosis factor-alpha, biology, LPS, Lipopolysaccharide, GSSG, Oxidized glutathione, MEF, Mouse embryonic fibroblasts, NF-kappa B, Gstm1, Glutathione S-transferase mu 1, Catalase, Endoplasmic Reticulum Stress, Glutathione, Liver, GSH, Reduced glutathione, 030220 oncology & carcinogenesis, JNK, c-Jun N-terminal kinase, lcsh:Medicine (General), Research Paper, medicine.medical_specialty, NF-E2-Related Factor 2, Glutamate-Cysteine Ligase, MKK, MAPK kinase, AP-1, Activator protein-1, IKK, IƙB Kinase, Gene Expression Regulation, Enzymologic, Superoxide dismutase, 03 medical and health sciences, Internal medicine, Glutamate cysteine ligase, EGFR, Epidermal growth factor receptor, medicine, Animals, Nuclear factor ƙB, And catalase, ChIP, Chromatin immunoprecipitation, Protein kinase B, NF-ƙB, Nuclear factor kappa B, Superoxide Dismutase, Superoxide dismutase 1, Superoxide dismutase 2, Organic Chemistry, ASK1, Apoptosis signal-regulating kinase 1, ATF2, activating transcription factor 2, 030104 developmental biology, Endocrinology, Enzyme, Hsp, Heat shock protein, lcsh:Biology (General), chemistry, biology.protein, SOD2, Mn-superoxide dismutase, MAPK, mitogen activated protein kinase, NEM, N-ethyl maleimide
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المؤلفون: Ana Teresa Serra, Tatiana Emanuelli, Greicy M.M. Conterato, Inês Prazeres, Maria Rosário Bronze, Paula Rossini Augusti, Cristiane Casagrande Denardin
المصدر: The Journal of Nutritional Biochemistry
مصطلحات موضوعية: Antioxidant, ARE, antioxidant responsive element, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, HepG2, hepatocellular carcinoma, ADAM17, A Disintegrin and metalloproteinase 17, Review Article, resveratrol, Pharmacology, CoVs, coronaviruses, Nrf2, nuclear factor erythroid 2-related factor 2, Biochemistry, EA, ellagic acid, Antioxidants, quercetin, GAE, gallic acid equivalents, 0302 clinical medicine, LDL, low-density lipoprotein, FRAP, ferric reducing antioxidant power, GSH, glutathione, TBARS, thiobarbituric acid reactive substances, TMPRSS2, transmembrane protease serine 2, IKK, IκB kinase, MLVEC, mouse lung vascular endothelial cells, ICAM-1, intercellular adhesion molecule 1, media_common, PBEC, primary cultured human bronchial epithelial cells, EC, (-)-epicatechin, MERS-CoV, Middle East respiratory syndrome coronavirus, SCFA, short-chain fatty acids, ECG, (-)-epicatechin gallate, MyD88, myeloid differentiation primary response 88, CA, coumaric acid, 8-OHdG, 8-hydroxy-deoxyguanosine, OS, oxidative stress, 030220 oncology & carcinogenesis, G-CSF, granulocyte-colony stimulating factor, NK, natural killer, sIL-6Rα, soluble form of IL-6 receptor, Drug, media_common.quotation_subject, Biological Availability, EGC, (-)-epigallocatechin, TRAP, total radical-trapping antioxidant potential, ACE2, angiotensin-converting enzyme 2, Antiviral Agents, MCP1, monocyte chemoattractant protein 1, WHO, World Health Organization, 03 medical and health sciences, Humans, Immunologic Factors, Molecular Biology, ARDS, acute respiratory distress syndrome, 3CLPro, chymotrypsin-like protease, Abbreviations: AAPH, 2,2′-azobis(2-amidinopropane) dihydrochloride, TEAC-CUPRAC, trolox equivalent antioxidant capacity - cupric ion reducing antioxidant capacity, AT1R, Ang II-receptor type 1, Nsp13, non-structural protein 13 helicase, IL, interleukin, Bioavailability, EC50, Half maximal effective concentration, TNF-α, tumor necrosis factor, 030104 developmental biology, chemistry, Curcumin, S - spike, CAT, catalase, NQO1, NAD(P)H quinone dehydrogenase 1, EGCG, epigallocatechin gallate, PSPL, purple sweet potato leaves, 0301 basic medicine, GCLC, glutamate–cysteine ligase catalytic subunit, Clinical Biochemistry, coronavirus, IC50, half maximal inhibitory concentration, Resveratrol, Gut flora, chemistry.chemical_compound, DNA, deoxyribonucleic acid, Biotransformation, TAC, total antioxidant capacity, oxidative stress, curcumin, NF-κB, nuclear factor kappa B, PRR– pattern recognition receptor, Nutrition and Dietetics, HBE, human bronchial epithelial cells, RBC, red blood cells, Anti-Inflammatory Agents, Non-Steroidal, FA, ferulic acid, JECFA, Joint FAO/WHO Expert Committee on Food Additives, NOX, NADPH oxidase, mRNA, messenger RNA, IFN, Interferon, OATP, organic anion transporting protein, QE, quercetin equivalents, EFSA, European food safety authority, MIP1α, macrophage inflammatory protein, COVID-19, coronavirus disease 19, PC, phenolic compounds, IBV, infectious bronchitis virus, SARS-CoV, severe acute respiratory syndrome coronavirus, ANG II, angiotensin II, Biology, FPP, fermented papaya preparation, SARS-CoV-2, severe acute respiratory syndrome coronavirus 2, BEAS-2B, primary cultured human bronchial epithelial cells, CYP, cytochrome, ROS, reactive oxygen species, Immune system, Phenols, SOD, superoxide dismutase, medicine, Animals, PLPro, papain-like protease, SARS-CoV-2, HMGB1– high-mobility group box 1, COVID-19, GA, gallic acid, biology.organism_classification, Vero E6, kidney epithelial cells, EGFR, epidermal growth factor receptor, Gastrointestinal Microbiome, immune system, PCA– protocatechuic acid, inflammation, Dietary Supplements, RNA, ribonucleic acid
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المؤلفون: Hideo Suzuki, Fumihiko Uchida, Kiyoji Tanaka, Takeji Sakae, Sechang Oh, Bokun Kim, Takehiko Tsujimoto, Junichi Shoda, Seiichiro Iizumi, Tomonori Isobe
المصدر: JHEP Reports
JHEP Reports, Vol 3, Iss 3, Pp 100253-(2021)مصطلحات موضوعية: FGF21, Adipose tissue, RC799-869, AST, aspartate aminotransferase, WFA+-M2BP, Wisteria floribunda agglutinin-positive human Mac-2 binding protein, NEFAs, non-esterified fatty acids, GGT, gamma-glutamyl transpeptidase, Weight loss, WC, waist circumference, Immunology and Allergy, Medicine, HO1, heme oxygenase 1, GPx, glutathione peroxidase, TNF-α, tumour necrosis factor alpha, Fatty liver, Gastroenterology, VAT, visceral adipose tissue, Diseases of the digestive system. Gastroenterology, TEI, total energy intake, TG, triglycerides, GCLM, glutamate-cysteine ligase modifier subunit, Esub, exercise (subset for which biological samples were available) group, Esmall, small amount of exercise group, Wtotal, weight-loss group, TBARS, thiobarbituric acid-reactive substances, BDNF, brain-derived neurotrophic factor, LPS, lipopolysaccharide, CAP, controlled attenuation parameter, NF-Score, NAFLD fibrosis score, medicine.symptom, Research Article, FAST-Score, FibroScan-AST score, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, LSM, liver stiffness measured using transient elastography, Hepatokine, FGF-21, fibroblast growth factor-21, Dietary restriction, NASH, non-alcoholic steatohepatitis, Elarge, large amount of exercise group, MVPA, moderate-to-vigorous intensity physical activity, SPARC, secreted protein acidic and rich in cysteine, NQO1, NAD(P)H quinone oxidoreductase, Myokine, ALT, alanine aminotransferase, Internal medicine, Internal Medicine, Aerobic exercise, Liver fat, Etotal, exercise group, FPG, fasting plasma glucose, KC, Kupffer cells, Se-P, selenoprotein-P, PBMCs, peripheral blood mononuclear cells, Nuclear factor-erythroid 2-related factor 2, Hepatology, Adiponectin, business.industry, Nrf2, nuclear factor E2-related factor 2, Wsub, weight-loss (subset for which biological samples were available) group, medicine.disease, HOMA-IR, homeostasis model assessment-insulin resistance, Regimen, Endocrinology, mnSOD, manganese superoxide dismutase, ANGPTL6, angiopoietin-like 6, Liver stiffness, business, GCLC, glutamate-cysteine ligase catalytic subunit
وصف الملف: application/pdf
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المؤلفون: Xiao-Fei Zhang, Yuchao Jiang, Hai-Jun Zhou, Qiang Zhou, Christiane J. Bruns, Peter J. Nelson, Zhefang Wang, Chenhao Zhou, Yue Zhao, Lisa Raatz, Dong-Mei Gao, Ning Ren, Jialei Sun, Wanyong Chen, Bo Hu
المصدر: Redox Biology
Redox Biology, Vol 41, Iss, Pp 101942-(2021)مصطلحات موضوعية: 0301 basic medicine, Medicine (General), [Mn], mitochondrial, Clinical Biochemistry, SOD1, superoxide dismutase 1, GCLC, Glutamate-cysteine ligase catalytic subunit, medicine.disease_cause, Biochemistry, Fer-1, ferrostatin-1, 0302 clinical medicine, NRF2, Nuclear factor E2-related factor 2, GSH, glutathione, Oxidoreductases Acting on Sulfur Group Donors, Biology (General), HCC, NQO1, NAD(P)H dehydrogenase [quinone], SFN, sulforaphane, SLC7A11, solute carrier family 7 member 11, Chemistry, Liver Neoplasms, H2O2, hydrogen dioxide, ROS, Necro, necrosulfonamide, Sorafenib, HO-1, Heme oxygenase 1, ErbB Receptors, Hepatocellular carcinoma, KEAP1, Kelch-like ECH-associated protein 1, Antioxidant, Oxidoreductases, Intracellular, Research Paper, medicine.drug, Carcinoma, Hepatocellular, QH301-705.5, NF-E2-Related Factor 2, Endosome, Context (language use), SOD2, Superoxide dismutase, OS, overall survival, 03 medical and health sciences, R5-920, ROS, reactive oxygen species, ΔΨm, mitochondrial membrane potential, In vivo, Cell Line, Tumor, QSOX1, EGFR, Epidermal growth factor receptor, medicine, Ferroptosis, Humans, neoplasms, Transcription factor, Organic Chemistry, NAC, N-acetyl-l-cysteine, NADPH, nicotinamide adenine dinucleotide phosphate, medicine.disease, digestive system diseases, TCGA, The Cancer Genome Altas, CAT, Catalase, AT, alkaloid trigonelline, QSOX1, Quiescin sulfhydryl oxidase 1, 030104 developmental biology, Cancer research, HCC, hepatocellular carcinoma, ARE, antioxidant reactive element, 030217 neurology & neurosurgery, Oxidative stress
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