المؤلفون: Karen A. Simmons, Li Luo, Erica J. Dashner-Titus, Debra MacKenzie, Laurie G. Hudson, Jodi R. Schilz

المصدر: Toxicology Reports, Vol 8, Iss, Pp 1917-1929 (2021)
Toxicology Reports

مصطلحات موضوعية: Sodium arsenite, Health, Toxicology and Mutagenesis, CD3, Uranyl acetate, GCLM, glutamate-cysteine ligase, APC, antigen presenting cell, Toxicology, NQO1, NAD(P)H quinone dehydrogenase, Arsenic, SOD1, super oxide dismutase 1, chemistry.chemical_compound, RA1190-1270, DEG, differentially expressed gene, Gene expression, T-lymphocytes, ComputingMethodologies_COMPUTERGRAPHICS, AUM, abandoned uranium mine, Th, T-helper, PCA, principal component analysis, Mixture toxicology, biology, MHC, major histone compatibility complex, CD28, Regular Article, Molecular biology, IFNγ, interferon gamma, chemistry, TCR, T-cell receptor, Toxicology. Poisons, biology.protein, Uranium, IL-2, interleukin 2, Co exposure, HMOX1, heme oxygenase 1

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e02ed1fd8c3c4023146cd14f108fc58a
https://doi.org/10.1016/j.toxrep.2021.11.019

المؤلفون: James E. Goldman, Alice Tang, Michelle L. Olsen, Natasha L. Pacheco, Jiangtao Li, Daniel Flint, Brett S. Phinney, Anthony W. Herren, Fatima Khan, Michael R. Heaven

المصدر: Molecular & cellular proteomics : MCP, vol 21, iss 1
Molecular & Cellular Proteomics : MCP

مصطلحات موضوعية: Proteomics, Cnp, 2′,3′-cyclic-nucleotide 3′-phosphodiesterase, Nadk2, NAD kinase 2, mitochondrial, Pck2, phosphoenolpyruvate carboxykinase [GTP], mitochondrial, Slc16a1, monocarboxylate transporter 1, PPAR, peroxisome proliferator-activated receptor, Mog, myelin-oligodendrocyte glycoprotein, Nfe2l2, nuclear factor erythroid 2-related factor 2, Mlc1, membrane protein MLC1, Biochemistry, C1qc, complement C1q subcomponent subunit C, Transgenic, Analytical Chemistry, Acadl, Long-chain specific acyl-CoA dehydrogenase, mitochondrial, Myelin, Mice, Gsr, glutathione reductase, mitochondrial, Cryl1, lambda-crystallin homolog, Sqstm1, sequestosome-1, BCA, bicinchoninic acid assay, LC3, microtubule-associated protein 1A/1B-light chain 3, Gliosis, SRM, selected reaction monitoring, Aetiology, Gclm, glutamate--cysteine ligase regulatory subunit, μDIA, micro-data-independent acquisition, Acsl3, long-chain-fatty-acid--CoA ligase 3, Cat, catalase, Acot2, Acyl-coenzyme A thioesterase 2, Glial fibrillary acidic protein, Rps27a, ubiquitin-40S ribosomal protein S27a, Acsl6, long-chain-fatty-acid--CoA ligase 6, Aldh1l1, Cytosolic 10-formyltetrahydrofolate dehydrogenase, Slc25a18, mitochondrial glutamate carrier 2, Bsn, protein bassoon, Fabp7, fatty acid binding protein, brain, Plp1, myelin proteolipid protein, Gsta3, glutathione S-transferase A3, Prdx6, peroxiredoxin-6, Alexander Disease, Slc6a11, sodium- and chloride-dependent GABA transporter 3, Ccnd2, G1/S-specific cyclin-D2, Stxbp5l, syntaxin-binding protein 5-like, GAPDH, glyceraldehyde 3 phosphate dehydrogenase, Slc6a17, sodium-dependent neutral amino acid transporter SLC6A17, Biochemistry & Molecular Biology, Ilk, integrin-linked protein kinase, Kcnj10, ATP-sensitive inward rectifier potassium channel 10, Ugt8, Gan, gigaxonin, Ttyh1, protein tweety homolog 1, Hsp27, heat shock protein beta-1, TBI, traumatic brain injury, reactive gliosis, Hmgcs2, hydroxymethylglutaryl-CoA synthase, mitochondrial, Idh2, isocitrate dehydrogenase [NADP], mitochondrial, KEGG, Kyoto encyclopedia of genes and genomes, Genetics, Humans, Gpr37l1, prosaposin receptor GPR37L1, Molecular Biology, Txnrd1, thioredoxin reductase 1, cytoplasmic, Slc38a3, sodium-coupled neutral amino acid transporter 3, Animal, DAVID, database for annotation, visualization and integrated discovery, GFAP, glial fibrillary acidic protein, astrocytes, Rack1, receptor of activated protein C kinase 1, Ugt8, 2-hydroxyacylsphingosine 1-beta-galactosyltransferase, Apoa1, apolipoprotein A-I, medicine.disease, Oligodendrocyte, GABA, gamma aminobutyric acid, Slc27a1, long-chain fatty acid transport protein 1, nervous system, Fabp7, Mutation, Mag, myelin-associated glycoprotein, Gclc, glutamate--cysteine ligase catalytic subunit, Gsto1, glutathione S-transferase omega-1, Ephx1, epoxide hydrolase 1, Gpx1, glutathione peroxidase 1, C1qa, complement C1q subcomponent subunit A, MDD, major depressive disorder, Cd44, Cd44 antigen, Slc4a4, electrogenic sodium bicarbonate cotransporter 1, Neurodegenerative, Dlg4, disks large homolog 4, TIC, total ion current, Gstm1, glutathione S-transferase Mu 1, Alexander disease, 2.1 Biological and endogenous factors, Functional ability, Ndrg2, protein NDRG2, Sfxn5, sideroflexin-5, Ca2, carbonic anhydrase 2, S1pr1, sphingosine 1-phosphate receptor 1, Gpx3, glutathione peroxidase 3, Snap25, synaptosomal-associated protein 25, Sparcl1, SPARC-like protein 1, medicine.diagnostic_test, Prdx1, peroxiredoxin-1, medicine.anatomical_structure, Neurological, Pgd, 6-phosphogluconate dehydrogenase, decarboxylating, Mbp, myelin basic protein, LPA, lysophosphatidic acid, Astrocyte, Gss, glutathione synthetase, Stat3, signal transducer and activator of transcription 3, Biotechnology, Sorbs1, Sorbin and SH3 domain-containing protein 1, RFs, Rosenthal fibers, Pygb, glycogen phosphorylase, brain form, Ctsd, cathepsin D, Ddx3x, ATP-dependent RNA helicase DDX3X, Fasn, fatty acid synthase, Slc1a2, excitatory amino acid transporter 2, PPP, pentose phosphate pathway, Mice, Transgenic, Plpp3, phospholipid phosphatase 3, Biology, C1qb, complement C1q subcomponent subunit B, CNS, central nervous system, Gja1, gap junction alpha-1 protein, PRM-MS, parallel reaction monitoring-mass spectrometry, TFA, trifluoro acetic acid, Vim, vimentin, Rare Diseases, Western blot, Downregulation and upregulation, Acox1, peroxisomal acyl-coenzyme A oxidase 1, Mobp, myelin-associated oligodendrocyte basic protein, medicine, Atp1b2, sodium/potassium-transporting ATPase subunit beta-2, Animals, Cryab, alpha-crystallin B chain, MS2, MS/MS or tandem mass spectrometry, Research, Neurosciences, Molecular biology, Ntrk2, BDNF/NT-3 growth factors receptor, Brain Disorders, AxD, Alexander disease, Disease Models, Animal, Acox3, Peroxisomal acyl-coenzyme A oxidase 3, Disease Models, biology.protein, Ugp2, UTP--glucose-1-phosphate uridylyl transferase, Acot1, Acyl-coenzyme A thioesterase 1

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27db73f1a1ae5cb5705d0a860adbda89
https://hdl.handle.net/10919/111277

المؤلفون: Bo Kong, Christina Ferrucci Da Silva, Lucy Lu, Thomas Hegyi, Naureen Memon, Michael J. Campbell, Le Zhan, Grace L. Guo, Jianliang Shen

المصدر: Acta Pharmaceutica Sinica B, Vol 10, Iss 1, Pp 153-158 (2020)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: Original article, medicine.medical_specialty, Total parenteral nutrition, Parenteral nutrition-associated liver disease, Ho-1, heme oxygenase 1, 03 medical and health sciences, Liver disease, chemistry.chemical_compound, GSTP1, Mt-1, metallothionein 1, ROS, reactive oxygen species, 0302 clinical medicine, Internal medicine, Gene expression, GSH, glutathione, NQO1, NAD(P)H:quinone acceptor oxidoreductase 1, medicine, Gstm3, glutathione S-transferase, mu 3, Gstm6, glutathione S-transferase, mu 6, Gstm1, glutathione S-transferase, mu 1, General Pharmacology, Toxicology and Pharmaceutics, 030304 developmental biology, Drug metabolism, Gpx3, glutathione peroxidase 3, TPN, total parenteral nutrition, 0303 health sciences, GADPH, glyceraldehyde 3-phosphate dehydrogenase, GCLM, business.industry, CYP450, cytochrome p450, lcsh:RM1-950, Gclc: glutamate-cysteine ligase catalytic subunit, Gclm: glutamate-cysteine ligase modifier subunit, Glutathione, FAs, fatty acids, medicine.disease, 3. Good health, Gstp1, glutathione S-transferase, pi 1, lcsh:Therapeutics. Pharmacology, GCLC, Parenteral nutrition, Endocrinology, Liver, chemistry, 030220 oncology & carcinogenesis, GSSG, GSH/glutathione disulfide, PNALD, parenteral nutrition-associated liver disease, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8caa990e4a3ed33d77d671f3206382aa
https://doi.org/10.1016/j.apsb.2019.10.012

المؤلفون: Wen-Xing Ding, Hartmut Jaeschke, David S Umbaugh, Olamide B. Adelusi, Giselle Sanchez-Guerrero, Nga T. Nguyen, Jephte Y. Akakpo, Anup Ramachandran

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3740-3755 (2021)

مصطلحات موضوعية: GSSG, glutathione disulfide, LOOH, lipid hydroperoxides, NQO1, NAD(P)H:quinone oxidoreductase 1, TLR, toll like receptor, HNE, 4-hydroxynonenal, NAC, N-acetylcysteine, Apoptosis, Review, Bioinformatics, SMAC/DIABLO, second mitochondria-derived activator of caspase/direct inhibitor of apoptosis-binding protein with low pI, GSH, glutathione, General Pharmacology, Toxicology and Pharmaceutics, Liver injury, Innate immunity, BSO, buthionine sulfoximine, mTORC1, mammalian target of rapamycin complex 1, MCP-1, monocyte chemoattractant protein-1, Mitochondria, CYP, cytochrome P450 enzymes, GPX4, glutathione peroxidase 4, NRF2, nuclear factor erythroid 2-related factor 2, KEAP1, Kelch-like ECH-associated protein 1, LPO, lipid peroxidation, NF-κB, nuclear factor κB, medicine.drug, DMSO, dimethylsulfoxide, Inflammatory response, Gclm, glutamate–cysteine ligase modifier subunit, HMGB1, high mobility group box protein 1, APAP, acetaminophen, ARE, antioxidant response element, RM1-950, TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling, UGT, UDP-glucuronosyltransferases, Necrotic cell, MPT, mitochondrial permeability transition, Acetaminophen hepatotoxicity, NRF2, ROS, reactive oxygen species, EndoG, endonuclease G, medicine, Autophagy, Injury mechanisms, Ferroptosis, MnSOD, manganese superoxide dismutase, Antipyretic drugs, MDA, malondialdehyde, Drug metabolism, business.industry, ATG, autophagy-related genes, PUFAs, polyunsaturated fatty acids, Liver failure, medicine.disease, CAD, caspase-activated DNase, Gclc, glutamate–cysteine ligase catalytic subunit, Acetaminophen, LC3, light chain 3, AIF, apoptosis-inducing factor, AMPK, AMP-activated protein kinase, DAMPs, damage-associated molecular patterns, JNK, c-jun N-terminal kinase, Therapeutics. Pharmacology, LAMP, lysosomal-associated membrane protein, business, NAPQI, N-acetyl-p-benzoquinone imine, FSP1, ferroptosis suppressing protein 1, MAP kinase, mitogen activated protein kinase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bde30b76b24a28a9236a78a6ec2b0a30
https://pubmed.ncbi.nlm.nih.gov/35024303

المؤلفون: Hongquan Guo, Xinfeng Liu, Juanji Li, Xiaolei Shi, Yi Xie, Pengfei Xu, Yunzi Li, Qian Liu, Rui Sun, Ye Hong, Mengna Peng, Gelin Xu

المصدر: Redox Biology
Redox Biology, Vol 18, Iss, Pp 158-172 (2018)

مصطلحات موضوعية: 0301 basic medicine, BRCT, BRCA1 C-terminal, GPX3, glutathione peroxidase 3, 4-HNE, 4-hydroxynonenol, OGD, oxygen-glucose deprivation, GCLM, glutamate-cysteine ligase regulator subunit, Iba-1, ionized calcium-binding adapter molecule-1, Clinical Biochemistry, SOD1, superoxide dismutase 1, HO-1, heme oxygenase 1, medicine.disease_cause, Biochemistry, NPCs, neural precursor cells, CaMKII, calcium/calmodulin-dependent protein kinase II, Lipid peroxidation, chemistry.chemical_compound, CA1, cornu ammonis 1, NSCs, neural stem cells, 3-NT, 3-nitrotyrosine, XRE, xenobiotic responsive element, skin and connective tissue diseases, lcsh:QH301-705.5, BER, base excision repair, GFP, green fluorescent protein, PSD95, postsynaptic density protein 95, chemistry.chemical_classification, lcsh:R5-920, DCX, doublecortin, ALS, amyotrophic lateral sclerosis, NRF2, nuclear factor (erythroid-derived 2)-like 2, GPX4, glutathione peroxidase 4, 8-OHDG, 8-hydroxy-2′-deoxyguanosine, Signal transduction, lcsh:Medicine (General), Ischemia/Reperfusion, Research Paper, NQO1, NAD(P)H dehydrogenase (quinone 1), DNA damage, DNA repair, Ischemia, I/R, ischemia/reperfusion, CNS, central nervous system, GCLC, glutamate-cysteine ligase catalytic, NRF2, 03 medical and health sciences, ROS, reactive oxygen species, NER, nucleotide excision repair, medicine, MCAO, middle cerebral artery occlusion, SOD2, superoxide dismutase 2, Reactive oxygen species, AD, Alzheimer disease, Organic Chemistry, GFAP, glial fibrillary acidic protein, BRCA1, medicine.disease, ARE, antioxidative response element, 030104 developmental biology, lcsh:Biology (General), chemistry, NHEJ, non-homologous end joining, Oxidative stress, BRCA1, breast cancer susceptibility protein 1, DSBs, double strand breaks, Cancer research, HR, homologous recombination, Reperfusion injury

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6e034e7c5102b1e7cd98f372f511aac
https://doi.org/10.1016/j.redox.2018.06.012

المؤلفون: Jennifer E. Gallagher, Dorothy Kisielewski, John F. Dillon, Shaun V. Walsh, Diane Cassidy, David J. Harrison, Ritu Sharma, Tadashi Honda, John D. Hayes, Alison D. McNeilly, Michael L.J. Ashford, Albena T. Dinkova-Kostova, Rory J. McCrimmon

المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 5, Iss 3, Pp 367-398 (2018)

مصطلحات موضوعية: NQO1, NAD(P)H:quinone oxidoreductase 1, TNF-α, tumor necrosis factor-α, IRE1α, inositol requiring kinase-1α, SCAD, short-chain acyl-CoA dehydrogenase, C/EBP, CCAAT/enhancer-binding protein, PCR, polymerase chain reaction, UPR, unfolded protein response, 0302 clinical medicine, Fibrosis, MGPAT, mitochondrial glycerol-3-phosphate acetyltransferase, ATF4, activating transcription factor-4, DGAT2, diacylglycerol acyltransferase-2, LXRα, liver X receptor α, Glucose homeostasis, eIf2α, eukaryotic translation initiation factor 2A, IKK, IκB kinase, ACOT7, acetyl-CoA thioesterase 7, Original Research, TGFβ, transforming growth factor beta-1, SLC7A11, solute carrier family 7 member 11, GSSG, oxidized glutathione, MTTP, microsomal triglyceride transfer protein, NASH, Gastroenterology, TXN1, thioredoxin-1, 3. Good health, ChREBP, carbohydrate-responsive element-binding protein, 030220 oncology & carcinogenesis, NASH, nonalcoholic steatohepatitis, medicine.medical_specialty, PARP, poly ADP ribose polymerase, qRT-PCR, quantitative reverse transcriptase PCR, GSTM1, glutathione S-transferase Mu-1, GCLC, glutamate-cysteine ligase catalytic, Nrf2, ACACA, acetyl-CoA carboxylase alpha, 03 medical and health sciences, FXR, farnesoid X receptor, Nrf2, NF-E2 p45-related factor 2, COX2, cyclooxygenase-2, Keap1, Kelch-like ECH-associated protein-1, PPARα, peroxisome proliferator-activated receptor α, PTT, pyruvate tolerance test, HMOX1, heme oxygenase-1, RC, regular chow, p58IPK, p58 inhibitor of the PKR kinase, medicine.disease, TBE-31, 030104 developmental biology, Endocrinology, COL1A1, collagen, type I, alpha-1, Unfolded protein response, CAT, catalase, 0301 basic medicine, PDI, protein disulfide isomerase, GSH, reduced glutathione, FASN, fatty acid synthase, BCL-2, B-cell lymphoma, MPO, myeloperoxidase, AP-1, activator protein 1, DMSO, dimethyl sulfoxide, medicine.disease_cause, SHP, small heterodimer partner, CDDO, 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid, CHOP, C/EBP homologous protein, TXNRD1, thioredoxin reductase-1, HF30Fr, high-fat diet with 30% fructose in drinking water, IκB, inhibitor of NF-κB, SFN, sulforaphane, ADRP, adipose differentiation-related protein, NAS, NAFLD activity score, GPX2, glutathione peroxidase-2, Chemistry, MCP-1, monocyte chemotactic protein-1, XBP1, X-box binding protein-1, SREBP-1c, sterol regulatory element-binding protein-1c, Lipogenesis, GTT, glucose tolerance test, PERK, PRK-like endoplasmic reticulum kinase, PTGR1, prostaglandin reductase-1, GSTA4, glutathione S-transferase Alpha-4, medicine.symptom, NAFLD, non-alcoholic fatty liver disease, α-SMA, alpha smooth muscle actin, ACOX2, acetyl-CoA oxidase 2, HFFr, high-fat diet with fructose in drinking water, NF-κB, nuclear factor-κB, GCLM, glutamate-cysteine ligase modifier, Inflammation, JNK1, c-Jun N-terminal kinase 1, CD36, cluster of differentiation 36, ER, endoplasmic reticulum, Insulin resistance, HF, high-fat, HF55Fr, high-fat diet with 55% fructose in drinking water, Internal medicine, ATF6, activating transcription factor-6, medicine, ApoB, apolipoprotein B, lcsh:RC799-869, CES1G, carboxylesterase 1g, ITT, insulin tolerance test, MCD, methionine- and choline-deficient, ACLY, ATP citrate lyase, Hepatology, SCD1, stearoyl-CoA desaturase-1, NOS2, nitric oxide synthase-2, PRDX6, peroxiredoxin 6, PPARγ, peroxisome proliferator-activated receptor γ, BIP, binding immunoglobulin protein, H&E, hematoxylin and eosin, lcsh:Diseases of the digestive system. Gastroenterology, Steatosis, CPT1A, carnitine palmitoyltransferase 1a, Oxidative stress

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebdd8de56b5ba950a8c970d72cce7012
https://doi.org/10.1016/j.jcmgh.2017.11.016

المؤلفون: Hideo Suzuki, Fumihiko Uchida, Kiyoji Tanaka, Takeji Sakae, Sechang Oh, Bokun Kim, Takehiko Tsujimoto, Junichi Shoda, Seiichiro Iizumi, Tomonori Isobe

المصدر: JHEP Reports
JHEP Reports, Vol 3, Iss 3, Pp 100253-(2021)

مصطلحات موضوعية: FGF21, Adipose tissue, RC799-869, AST, aspartate aminotransferase, WFA+-M2BP, Wisteria floribunda agglutinin-positive human Mac-2 binding protein, NEFAs, non-esterified fatty acids, GGT, gamma-glutamyl transpeptidase, Weight loss, WC, waist circumference, Immunology and Allergy, Medicine, HO1, heme oxygenase 1, GPx, glutathione peroxidase, TNF-α, tumour necrosis factor alpha, Fatty liver, Gastroenterology, VAT, visceral adipose tissue, Diseases of the digestive system. Gastroenterology, TEI, total energy intake, TG, triglycerides, GCLM, glutamate-cysteine ligase modifier subunit, Esub, exercise (subset for which biological samples were available) group, Esmall, small amount of exercise group, Wtotal, weight-loss group, TBARS, thiobarbituric acid-reactive substances, BDNF, brain-derived neurotrophic factor, LPS, lipopolysaccharide, CAP, controlled attenuation parameter, NF-Score, NAFLD fibrosis score, medicine.symptom, Research Article, FAST-Score, FibroScan-AST score, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, LSM, liver stiffness measured using transient elastography, Hepatokine, FGF-21, fibroblast growth factor-21, Dietary restriction, NASH, non-alcoholic steatohepatitis, Elarge, large amount of exercise group, MVPA, moderate-to-vigorous intensity physical activity, SPARC, secreted protein acidic and rich in cysteine, NQO1, NAD(P)H quinone oxidoreductase, Myokine, ALT, alanine aminotransferase, Internal medicine, Internal Medicine, Aerobic exercise, Liver fat, Etotal, exercise group, FPG, fasting plasma glucose, KC, Kupffer cells, Se-P, selenoprotein-P, PBMCs, peripheral blood mononuclear cells, Nuclear factor-erythroid 2-related factor 2, Hepatology, Adiponectin, business.industry, Nrf2, nuclear factor E2-related factor 2, Wsub, weight-loss (subset for which biological samples were available) group, medicine.disease, HOMA-IR, homeostasis model assessment-insulin resistance, Regimen, Endocrinology, mnSOD, manganese superoxide dismutase, ANGPTL6, angiopoietin-like 6, Liver stiffness, business, GCLC, glutamate-cysteine ligase catalytic subunit

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d799758e6591ac117326fd2a92b672f8
https://tsukuba.repo.nii.ac.jp/records/2004615

المؤلفون: Antonio Cuadrado, Marta Pajares, Ana I. Rojo

المساهمون: Ministerio de Economía y Competitividad (España), Universidad Autónoma de Madrid

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname
Redox Biology, Vol 11, Iss, Pp 543-553 (2017)
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Redox Biology

مصطلحات موضوعية: GSSG, glutathione disulfide, NQO1, NAD(P)H:quinone oxidoreductase 1, PrP, prionic protein, CG islands, cytosine guanine islands, Review Article, Biochemistry, UPR, unfolded protein response, HD, Huntington's disease, NRF1, lcsh:QH301-705.5, GFP, green fluorescent protein, GSH, glutathione (c-glutamyl-l-cysteinylglycine), LIR, LC3 interacting region, Brain, ALS, amyotrophic lateral sclerosis, GSK-3, glycogen synthase kinase-3, Cell biology, NRF2, nuclear factor (erythroid-derived 2)-like 2, ASK1, apoptosis-signal-regulating kinase 1, lcsh:Medicine (General), FOXO, forkhead box, β-TrCP, β-transducin repeat containing E3 ubiquitin protein ligase, NF-E2-Related Factor 2, ARE, antioxidant response element, mTOR, mammalian target of rapamycin, UBA, ubiquitin associated domain, Protein Aggregation, Pathological, 03 medical and health sciences, XBP1, X box-binding protein 1, PKC, protein kinase C, γ-GCL, γ -glutamylcysteine synthetase, Humans, α-SYN, alpha synuclein, CJD, Creutzfeldt Jakob disease, HMOX1, heme oxygenase-1, Proteasome, PI3K, phosphatidyl inositol-3 kinase, γGS, γ -glutamate cysteine synthetase, PRX, peroxiredoxin, 030104 developmental biology, Proteostasis, Oxidative stress, Unfolded protein response, TFEB, PKA, protein kinase A, 0301 basic medicine, PDI, protein disulfide isomerase, Proteome, Clinical Biochemistry, Aβ, amyloid beta, GPX, glutathione peroxidase, Endoplasmic Reticulum, CSF, cerebrospinal fluid, PD, Parkinson's disease, GST, glutathione S-transferase, TFEB, transcription factor EB, ASK1, SOD1, Cu/Zn-superoxide dismutase 1, MAPKs, mitogen-activated protein kinases, SFN, sulforaphane, Genetics, PS1, presenilin 1, lcsh:R5-920, MPTP, 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine, Neurodegenerative diseases, NRF1, nuclear factor (erythroid-derived 2)-like 1, GR, GSR, glutathione reductase, ChIP, chromatin immunoprecipitation, GCLM, glutamate-cysteine ligase modulatory subunit, IRE1, inositol-requiring kinase 1, JNK, c-Jun N-terminal kinase, AD, Alzheimer's disease, DMF, dimethyl fumarate, Proteasome Endopeptidase Complex, XBP1, TAK1, TGF-β-activated kinase 1, γGT, γ -glutamyl transpeptidase, Protein degradation, Biology, ER, endoplasmic reticulum, ROS, reactive oxygen species, UPS, ubiquitin proteasome system, APP, amyloid precursor protein, Autophagy, D3T, 1,2-dithiole-3-thione, Transcription factor, MEF, mouse embryonic fibroblasts, Htt, huntingtin, Ubiquitin, Organic Chemistry, ERO1, sulfhydryl oxidase endoplasmic oxidoreductin 1, AMPK, AMP-activated protein kinase, lcsh:Biology (General), ATF-6, activating transcription factor 6, PERK, pancreatic ER eIF2α kinase, GLT-1, glutamate transporter 1, GCLC, glutamate-cysteine ligase catalytic subunit, KEAP1, kelch-like ECH-associated protein 1

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f92176ef6df1b38f56b20a10b5b1ad8

المؤلفون: Anna-Liisa Levonen, Carlos Cruz Cortés, Tommi Patinen, Jouni Härkönen, Ashik Jawahar Deen, Simone Adinolfi

المصدر: Redox Biology, Vol 23, Iss, Pp-(2019)
Redox Biology

مصطلحات موضوعية: RES, Reactive electrophilic species, ARE, Antioxidant response element, Biochemistry, Lipid peroxidation, 0302 clinical medicine, Heat Shock Transcription Factors, HSR, Heat shock response, lcsh:QH301-705.5, Protein lipoxidation, SILAC, Stable isotope labeling with amino acids in cell culture, chemistry.chemical_classification, CUL3, (Cullin-3)-ubiquitin E3 ligase complex, Kelch-Like ECH-Associated Protein 1, PGA2, Prostaglandin A2, NTR, N-terminal region, CTD, C-terminal domain, RD, Regulatory domain, Cell biology, NO2-CLA, nitro-conjugated linoleic acid, KEAP1, Kelch-like ECH-associated protein 1, OA-NO2, Nitro-oleic acid, lcsh:Medicine (General), NF-E2-Related Factor 2, 4-HNE, 4-hydroxy-2-nonenal, NRF2, LNO2, 9-, 10-, 12-, or 13-nitro-octadeca-9, 12-dienoic acid, 03 medical and health sciences, Humans, NTD, N-terminal domain, PARP13, Poly(ADP-ribose) Polymerase 13, Heat shock, LDE, Lipid-derived electrophiles, MS, Mass spectrometry, GCLC, Glutamate cysteine ligase catalytic, POLK, DNA polymerase kappa, Heat shock proteins, SH, sulfhydryl group, T-REX, Targetable reactive electrophiles and oxidants, DMSO, Dimethyl sulfoxide, 15d-PGJ2, 15-deoxy-Δ-12,14-prostaglandin J2, SQSTM1, Autophagosome cargo protein Sequestosome 1, KEAP1, 030104 developmental biology, HSP90, 90-kDa heat shock proteins from HSP90 family, chemistry, Redox regulation, Lipid Peroxidation, Biomarkers, 030217 neurology & neurosurgery, PEIPC, 1-palmitoyl-2-(5, 6)-epoxy isoprostane E2)-sn-glycero-3-phosphocholine, ROS, Reactive oxygen species, LC-MS, Liquid chromatography-mass spectrometry, 0301 basic medicine, Cysteine modification, Clinical Biochemistry, H2O2, Hydrogen peroxide, IA, Iodoacetamide alkyne, PARP1, Poly(ADP-ribose) polymerase 1, chemistry.chemical_compound, HSPD1/E1, Heat shock protein family D/E (Hsp60/Hsp10) member 1, LOX12/15, 12/15-Lipoxygenase, HSF1, HSPA8, Heat shock protein family A (Hsp70) member 8, Ub, ubiquitin, lcsh:R5-920, IER5, Immediate early response 5, HSP, Heat shock protein, NQO1, NAD(P)H:quione oxidoreductase 1, HSP40, 40-kDa heat shock proteins from HSP40 family, LZ4, Leucine zipper 4 domain, sMAF, small musculoaponeurotic fibrosarcoma oncogene homolog protein family, TEV, Tobacco etch virus, HSE, Heat shock element, GST, Gluthathione S-transferase, Second messenger system, Signal transduction, Oxidation-Reduction, Signal Transduction, CTAD, C-terminal transactivation domain, MD, Middle domain, ZAK, Animal-specific MAP kinase found in stress responses, Stress, Physiological, Implications of lipoxidation in cellular defense and stress pathway, Heat shock protein, GCLM, Glutamate-Cysteine Ligase Modifier Subunit, Animals, aLA, Alkyne-labeled linoleic acid, oxPAPC, Oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine, Cysteine, ABPP, Affinity based protein profiling, IVR, Intervening region, Stress response, PRDX1, Peroxiredoxin 1, Organic Chemistry, Neh, Nrf2-ECH homology, HSF1, Heat shock factor 1, NRF2, NF-E2-related factor 2, Oxidative Stress, BTB, Broad complex, Tram-track, and Bric-a-Brac, Enzyme, lcsh:Biology (General), DBD, DNA binding domain, TXNR1D1, Thioredoxin reductase 1, LZ1–3, Leucine zipper 1–3 domains, HSP70, 70-kDa heat shock proteins from HSP70 family, G-REX, Genome-wide variant of T-REX, MRP, Multidrug-resistance-associated protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aafcf94c34748fdbf80fa6cb081441fc
http://www.sciencedirect.com/science/article/pii/S221323171831067X

المؤلفون: Jayne Louise Wilson, Roberto Motterlini, Lucie Muchová, Thierry Martens, Aniket Nikam, Anthony Ollivier, Sylvie Manin, Roberta Foresti, Sabrina Djouadi, Michael Rivard

المساهمون: Institut de Chimie et des Matériaux Paris-Est (ICMPE), Institut de Chimie du CNRS (INC)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Redox Biology
Redox Biology, Elsevier, 2019, 20, pp.334-348. ⟨10.1016/j.redox.2018.10.020⟩
Redox Biology, Vol 20, Iss, Pp 334-348 (2019)

مصطلحات موضوعية: Lipopolysaccharides, Male, 0301 basic medicine, Lipopolysaccharide, NQO1, NAD(P)H:quinone oxidoreductase 1, Clinical Biochemistry, Anti-Inflammatory Agents, Gene Expression, AST, aspartate aminotransferase, Pharmacology, medicine.disease_cause, Nrf2, nuclear factor erythroid 2-related factor 2, TNF-α, tumor necrosis factor-α, Biochemistry, Antioxidants, Dual-activity molecules, Mice, chemistry.chemical_compound, ARG1, arginase 1, CO-RMs, CO-releasing molecules, 0302 clinical medicine, LC-MS/MS, liquid chromatography-tandem mass spectrometry, EPF, ethyl prop-2-yn-1-yl fumarate, IL-6, interleukin-6, lcsh:QH301-705.5, Cells, Cultured, ComputingMilieux_MISCELLANEOUS, Mice, Knockout, lcsh:R5-920, M2, anti-inflammatory macrophages, Carbon Monoxide, LDH, lactate dehydrogenase, Dimethyl fumarate, IL-10, interleukin-10, [SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences, HMOX1, heme oxygenase-1 gene, 3. Good health, Nrf2 activators, CO, carbon monoxide, iNOS, inducible nitric oxide synthase, LPS, lipopolysaccharide, Cytokines, Microglia, Inflammation Mediators, medicine.symptom, lcsh:Medicine (General), Research Paper, M1, pro-inflammatory macrophages, IL-1β, interleukin-1β, NF-E2-Related Factor 2, GCLC, glutamate cysteine ligase C, Carbon monoxide (CO), Inflammation, HO-1, heme oxygenase-1 protein, GCLM, glutamate cysteine ligase M, 03 medical and health sciences, In vivo, ALT, alanine aminotransferase, medicine, Animals, [CHIM.COOR]Chemical Sciences/Coordination chemistry, ARG1, MCP-1/CCL2, monocyte chemoattractant protein-1, ALP, alkaline phosphatase, Macrophage phenotype, Activator (genetics), Macrophages, Organic Chemistry, In vitro, Disease Models, Animal, Oxidative Stress, 030104 developmental biology, lcsh:Biology (General), chemistry, HYCOs, HYbrid CO-releasing molecules, COHb, carbonmonoxy hemoglobin, Heme Oxygenase-1, 030217 neurology & neurosurgery, Oxidative stress, Hb, hemoglobin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe74c139a3bec4e624e4d5757b02f915
https://hal.archives-ouvertes.fr/hal-03124423