نتائج البحث - "GPI-Linked Proteins/metabolism"

1

Autocrine Adenosine Regulates Tumor Polyfunctional CD73+CD4+ Effector T Cells Devoid of Immune Checkpoints

المؤلفون: Pedro Romero, Marion Bossennec, Isabelle Durand, Bertrand Dubois, Christelle Machon, David Bauché, Julien Faget, Nicolas Gourdin, Christophe Caux, Jérôme Guitton, Julien C. Marie, Camilla Jandus, Nicolas Chopin, Olivier Tredan, Christine Ménétrier-Caux, Céline Rodriguez, Selena Vigano

المساهمون: Centre de Recherche en Cancérologie de Lyon (UNICANCER/CRCL), Centre Léon Bérard [Lyon]-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université de Lausanne (UNIL), Centre Hospitalier Lyon Sud [CHU - HCL] (CHLS), Hospices Civils de Lyon (HCL), Institut des Sciences Pharmaceutiques et Biologiques (ISPB), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon, German Cancer Research Center - Deutsches Krebsforschungszentrum [Heidelberg] (DKFZ), Institut de Recherche en Cancérologie de Montpellier (IRCM - U1194 Inserm - UM), CRLCC Val d'Aurelle - Paul Lamarque-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Department of Medical Oncology [Lyon], Centre Léon Bérard [Lyon], Centre de Recherche en Cancérologie de Lyon (CRCL), Université de Lyon-Université de Lyon-Centre Léon Bérard [Lyon]-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), CRLCC Val d'Aurelle - Paul Lamarque-Université de Montpellier (UM)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Lausanne = University of Lausanne (UNIL), Herrada, Anthony

المصدر: Cancer Research, Vol. 78, No 13 (2018) pp. 3604-3618
Cancer Research
Cancer Research, American Association for Cancer Research, 2018, 78 (13), pp.3604-3618. ⟨10.1158/0008-5472.CAN-17-2405⟩
Cancer research, vol. 78, no. 13, pp. 3604-3618
Cancer Research, 2018, 78 (13), pp.3604-3618. ⟨10.1158/0008-5472.CAN-17-2405⟩

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, T-Lymphocytes, Drug Resistance, [SDV.CAN]Life Sciences [q-bio]/Cancer, Antineoplastic Agents, chemical and pharmacologic phenomena, C-C chemokine receptor type 6, CXCR3, GPI-Linked Proteins/metabolism, Helper-Inducer/immunology/metabolism, 5'-Nucleotidase/metabolism, Adenosine/metabolism, Antineoplastic Agents, Immunological/pharmacology, Antineoplastic Agents, Immunological/therapeutic use, Apyrase/metabolism, Breast Neoplasms/drug therapy, Breast Neoplasms/immunology, Breast Neoplasms/pathology, Costimulatory and Inhibitory T-Cell Receptors/antagonists & inhibitors, Costimulatory and Inhibitory T-Cell Receptors/metabolism, Drug Resistance, Neoplasm/immunology, Female, Humans, Interleukin-17/metabolism, Lymphocytes, Tumor-Infiltrating/immunology, Lymphocytes, Tumor-Infiltrating/metabolism, Ovarian Neoplasms/drug therapy, Ovarian Neoplasms/immunology, Ovarian Neoplasms/pathology, T-Lymphocytes, Helper-Inducer/immunology, T-Lymphocytes, Helper-Inducer/metabolism, T-Lymphocytes, Regulatory/immunology, T-Lymphocytes, Regulatory/metabolism, Tumor Escape/immunology, Regulatory/immunology/metabolism, Interleukin 22, 03 medical and health sciences, Immune system, [SDV.CAN] Life Sciences [q-bio]/Cancer, Lymphocytes, Autocrine signalling, Costimulatory and Inhibitory T-Cell Receptors/antagonists & inhibitors/metabolism, [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, Breast Neoplasms/drug therapy/immunology/pathology, Chemistry, Effector, Neoplasm/immunology, Immunological/pharmacology/therapeutic use, Immune checkpoint, Tumor-Infiltrating/immunology/metabolism, 030104 developmental biology, Oncology, Tumor Escape, Cancer research, Ovarian Neoplasms/drug therapy/immunology/pathology, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8375fbfa2c51d166ee5ae1ba8adac560
https://doi.org/10.1158/0008-5472.can-17-2405

2

LC3C Contributes to Vpu-Mediated Antagonism of BST2/Tetherin Restriction on HIV-1 Release through a Non-canonical Autophagy Pathway

المؤلفون: Stéphane Frémont, Aurelia Kuster, Olivier Leymarie, Ursula Madjo, Katy Janvier, Sarah Gallois-Montbrun, Clarisse Berlioz-Torrent, Mélanie Nehlich

المساهمون: Institut Cochin (IC UM3 (UMR 8104 / U1016)), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), U.M. holds a fellowship from the 'Ministère français de l’enseignement supérieur et de la Recherche' and then from SIDACTION. O.L. holds a fellowship from SIDACTION and then from ANRS, S.F. holds a fellowship from the 'Fondation pour la recherche médicale,' and A.K. holds a fellowship from ANRS. This work is funded by ANRS., We thank Patrice Codogno, Stéphane Emiliani, Monica Naughtin, and Florence Margottin-Goguet for helpful discussions and Annegret Pelchen-Mathews for IEM images. We thank the Imaging Facility and the Immunobiology Facility of the Cochin Institute for technical assistance. The following reagents were obtained through the NIBCS: HIV-1 gp120 monoclonal antibody (2G12) from Dr. H. Katinger, mouse antibodies against CAp24 (38:96K and EF7, EVA365, and 366, respectively) from B. Wahren and p17 (4C9, ARP342) from R.B. Ferns and R.S. Tedder. The following reagents were obtained through the NIH AIDS reagent program: anti-human BST2 from Drs. K. Strebel and A. Andrew, HIV-1 NL4-3 Vpu antiserum from Drs. K. Strebel and F. Maldarelli, and pNL4-3 from Dr. M. Martin. We thank Dr. K. Strebel for the gift of pNL4-3/Udel proviral DNA, Dr. T. Johansen for the human ATG8 ortholog cDNA, Dr. M. Faure for pCI-3xFlag-p62 and pCR3-3xFlag-NDP52, and Dr. P.D. Bieniasz for pNL4-3(MA/YFP) proviral DNA.

المصدر: Cell Reports
Cell Reports, Elsevier Inc, 2016, 17 (9), pp.2221-2233. ⟨10.1016/j.celrep.2016.10.045⟩

مصطلحات موضوعية: 0301 basic medicine, MESH: Human Immunodeficiency Virus Proteins/metabolism, [SDV]Life Sciences [q-bio], LC3C, animal diseases, viruses, Human Immunodeficiency Virus Proteins, Autophagy-Related Proteins, restriction, MESH: Amino Acid Sequence, MESH: Virus Release, MESH: Human Immunodeficiency Virus Proteins/chemistry, Viral Regulatory and Accessory Proteins, Virus Release, Budding, virus diseases, tetherin, LC3-associated phagocytosis, 3. Good health, Cell biology, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, MESH: HEK293 Cells, ATG5, Microtubule-Associated Proteins, Protein Binding, autophagy, ATG8, Phagocytosis, MESH: Viral Regulatory and Accessory Proteins/metabolism, BST2, Biology, GPI-Linked Proteins, MESH: Antigens, CD/metabolism, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Viral envelope, Antigens, CD, Vpu, Humans, MESH: Protein Binding, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Amino Acid Sequence, MESH: GPI-Linked Proteins/metabolism, MESH: Autophagy, MESH: Autophagy-Related Proteins/metabolism, MESH: HIV-1/metabolism, MESH: Humans, Autophagy, biochemical phenomena, metabolism, and nutrition, Virology, ATG, MESH: Viral Regulatory and Accessory Proteins/chemistry, HEK293 Cells, 030104 developmental biology, MESH: HeLa Cells, HIV-1, Tetherin, MESH: Microtubule-Associated Proteins/metabolism, Antagonism, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5542ca7e7c71ac0bf9de4121a4da4df7
https://doi.org/10.1016/j.celrep.2016.10.045

View record from ScienceDirect

3

The effect of helminths on granulocyte activation : a cluster-randomized placebo-controlled trial in Indonesia

المؤلفون: Erliyani Sartono, Leo Koenderman, Thomas B. Nutman, Karin de Ruiter, Johannes W. A. Smit, Taniawati Supali, Maria Yazdanbakhsh, Dicky L. Tahapary

المصدر: Journal of Infectious Diseases, 219(9), 1474. Oxford University Press
The Journal of Infectious Diseases, 219, 1474-1482
The Journal of Infectious Diseases, 219, 9, pp. 1474-1482
Journal of Infectious Diseases, 219(9), 1474-1482. OXFORD UNIV PRESS INC

مصطلحات موضوعية: 0301 basic medicine, Antigens, Differentiation, T-Lymphocyte, Male, Placebo-controlled study, Helminthiasis, Antigens, Differentiation, T-Lymphocyte/metabolism, Antigens, CD/metabolism, Gastroenterology, L-Selectin/metabolism, Neutrophil Activation, law.invention, T-Lymphocyte/metabolism, Leukocyte Count, 0302 clinical medicine, Randomized controlled trial, neutrophils, law, Lectins, Receptors, Helminthiasis/blood, Medicine, Immunology and Allergy, activation markers, 030212 general & internal medicine, L-Selectin, Non-U.S. Gov't, Anthelmintics, Eosinophil-Derived Neurotoxin/blood, CD11b Antigen, Eosinophil Granule Proteins/blood, Research Support, Non-U.S. Gov't, CD/metabolism, Albendazole/therapeutic use, Eosinophil Granule Proteins, Middle Aged, Complement 3b/metabolism, Infectious Diseases, Differentiation, Randomized Controlled Trial, Female, CD11b Antigen/metabolism, eosinophils, Eosinophil Cationic Protein/blood, medicine.drug, Cell Adhesion Molecules/metabolism, Adult, Asian Continental Ancestry Group, Granulocyte activation, medicine.medical_specialty, education, European Continental Ancestry Group, Eosinophil-Derived Neurotoxin, Disease cluster, Albendazole, GPI-Linked Proteins, Research Support, Eosinophil Major Basic Protein, White People, Healthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18], GPI-Linked Proteins/metabolism, 03 medical and health sciences, Major Articles and Brief Reports, Asian People, Antigens, CD, Internal medicine, Eosinophil Major Basic Protein/blood, Receptors, Complement 3b/metabolism, granular proteins, Journal Article, Humans, Lectins, C-Type, Antigens, C-Type/metabolism, Eosinophils/immunology, helminths, Anthelmintics/therapeutic use, business.industry, Eosinophil Cationic Protein, Neutrophils/immunology, Case-control study, medicine.disease, 030104 developmental biology, Indonesia, Case-Control Studies, Receptors, Complement 3b, business, Cell Adhesion Molecules, Biomarkers, Biomarkers/blood, Lectins, C-Type/metabolism

وصف الملف: image/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e63a3d16b4bbe4dccb832ca424c31f0
https://dspace.library.uu.nl/handle/1874/390519

4

Outcomes of controlled human malaria infection after BCG vaccination

المصدر: Nature Communications, 10
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Walk, J, de Bree, L C J, Graumans, W, Stoter, R, van Gemert, G J, van de Vegte-Bolmer, M, Teelen, K, Hermsen, C C, Arts, R J W, Behet, M C, Keramati, F, Moorlag, S J C F M, Yang, A S P, van Crevel, R, Aaby, P, de Mast, Q, van der Ven, A J A M, Stabell Benn, C, Netea, M G & Sauerwein, R W 2019, ' Outcomes of controlled human malaria infection after BCG vaccination ', Nature Communications, vol. 10, 874 . https://doi.org/10.1038/s41467-019-08659-3
Nature Communications

مصطلحات موضوعية: Male, 0301 basic medicine, Malaria, Falciparum/immunology, lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4], General Physics and Astronomy, 02 engineering and technology, Parasitemia, Lymphocyte Activation, Granzymes, Malaria, Falciparum, lcsh:Science, HLA-DR Antigens/metabolism, Multidisciplinary, Malaria vaccine, Vaccination, Granzymes/blood, 021001 nanoscience & nanotechnology, 3. Good health, Killer Cells, Natural, C-Reactive Protein, medicine.anatomical_structure, Immunologic Memory/immunology, Killer Cells, Natural/immunology, BCG Vaccine, Cytokines, Parasitemia/prevention & control, Female, 0210 nano-technology, Adult, B7-2 Antigen/metabolism, Adolescent, Science, Plasmodium falciparum, Anopheles/parasitology, Lymphocyte Activation/immunology, GPI-Linked Proteins, Cytokines/blood, Article, General Biochemistry, Genetics and Molecular Biology, GPI-Linked Proteins/metabolism, Interferon-gamma, Young Adult, 03 medical and health sciences, All institutes and research themes of the Radboud University Medical Center, Immunity, BCG Vaccine/administration & dosage, Immunity, Innate/immunology, Plasmodium falciparum/immunology, Anopheles, parasitic diseases, medicine, Animals, Humans, Adverse effect, Molecular Biology, business.industry, C-Reactive Protein/metabolism, Monocyte, Receptors, IgG, HLA-DR Antigens, General Chemistry, Receptors, IgG/metabolism, medicine.disease, Immunity, Innate, 030104 developmental biology, lnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4], Immunology, lcsh:Q, B7-2 Antigen, business, Immunologic Memory, BCG vaccine, Interferon-gamma/blood, Malaria