المؤلفون: Ren H; Department of Ophthalmology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China., Sun Y; Jiangsu Institute of Hematology, National Clinical Research Center for Hematologic Diseases, NHC Key Laboratory of Thrombosis and Hemostasis, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China., Li Y; Department of Ophthalmology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China., Yuan X; Department of Ophthalmology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China., Jiang B; Department of Ophthalmology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China., Zhang W; Jiangsu Institute of Hematology, National Clinical Research Center for Hematologic Diseases, NHC Key Laboratory of Thrombosis and Hemostasis, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China., Liu G; Department of Ophthalmology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.; Jiangsu Clinical Immunology Institute, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China., Lu P; Department of Ophthalmology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.; Jiangsu Clinical Immunology Institute, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.

المصدر: Current eye research [Curr Eye Res] 2024 Jul; Vol. 49 (7), pp. 731-741. Date of Electronic Publication: 2024 Mar 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8104312 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2202 (Electronic) Linking ISSN: 02713683 NLM ISO Abbreviation: Curr Eye Res Subsets: MEDLINE

مواضيع طبية MeSH: Disease Models, Animal* , Fibrinogen*/metabolism , Platelet Glycoprotein GPIIb-IIIa Complex*/metabolism , Platelet Glycoprotein GPIIb-IIIa Complex*/antagonists & inhibitors , Retinal Vein Occlusion*/drug therapy , Retinal Vein Occlusion*/metabolism, Aged ; Animals ; Female ; Humans ; Male ; Mice ; Middle Aged ; Blood Platelets/metabolism ; Flow Cytometry ; Mice, Inbred C57BL ; Platelet Aggregation/physiology ; Platelet Aggregation/drug effects ; Platelet Aggregation Inhibitors/therapeutic use ; Real-Time Polymerase Chain Reaction ; Integrin alpha2/metabolism

المؤلفون: Wang L; Laboratory of Blood and Vascular Biology, The Rockefeller University, New York, NY., Wang J; Laboratory of Molecular Electron Microscopy, The Rockefeller University, New York, NY., Li J; Laboratory of Blood and Vascular Biology, The Rockefeller University, New York, NY., Walz T; Laboratory of Molecular Electron Microscopy, The Rockefeller University, New York, NY., Coller BS; Laboratory of Blood and Vascular Biology, The Rockefeller University, New York, NY.

المصدر: Blood advances [Blood Adv] 2024 Aug 27; Vol. 8 (16), pp. 4398-4409.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE

مواضيع طبية MeSH: Platelet Glycoprotein GPIIb-IIIa Complex*/metabolism , Platelet Glycoprotein GPIIb-IIIa Complex*/immunology , Platelet Glycoprotein GPIIb-IIIa Complex*/chemistry , Antibodies, Monoclonal*/chemistry , Protein Binding*, Humans ; Ligands ; Blood Platelets/metabolism ; Platelet Aggregation/drug effects ; Protein Conformation ; Allosteric Regulation ; Protein Disulfide-Isomerases/metabolism ; Protein Disulfide-Isomerases/chemistry ; Protein Disulfide-Isomerases/antagonists & inhibitors

المؤلفون: Joshi O; Department of Biomedical Engineering, University of Utah, Salt Lake City, Utah, USA.; Scientific Computing and Imaging Institute, University of Utah, Salt Lake City, Utah, USA., Skóra T; Scientific Computing and Imaging Institute, University of Utah, Salt Lake City, Utah, USA., Yarema A; Department of Biomedical Engineering, University of Utah, Salt Lake City, Utah, USA., Rabbitt RD; Department of Biomedical Engineering, University of Utah, Salt Lake City, Utah, USA., Bidone TC; Department of Biomedical Engineering, University of Utah, Salt Lake City, Utah, USA.; Scientific Computing and Imaging Institute, University of Utah, Salt Lake City, Utah, USA.; Department of Molecular Pharmaceutics, University of Utah, Salt Lake City, Utah, USA.; Department of Biochemistry, University of Utah, Salt Lake City, Utah, USA.

المصدر: Cytoskeleton (Hoboken, N.J.) [Cytoskeleton (Hoboken)] 2024 Aug; Vol. 81 (8), pp. 393-408. Date of Electronic Publication: 2024 Apr 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 101523844 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1949-3592 (Electronic) Linking ISSN: 19493592 NLM ISO Abbreviation: Cytoskeleton (Hoboken) Subsets: MEDLINE

مواضيع طبية MeSH: Platelet Glycoprotein GPIIb-IIIa Complex*/metabolism , Platelet Glycoprotein GPIIb-IIIa Complex*/chemistry , Protein Domains*, Humans ; Molecular Dynamics Simulation

المؤلفون: Huo T; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA., Wu H; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Graduate School of Baylor College of Medicine, Baylor College of Medicine, Houston, TX 77030, USA., Moussa Z; Department of Biology and Biochemistry, University of Houston, Houston, TX 77204, USA., Sen M; Department of Biology and Biochemistry, University of Houston, Houston, TX 77204, USA., Dalton V; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA., Wang Z; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Cryo-EM/ET CPRIT Core, Baylor College of Medicine, Houston, TX 77030, USA; Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address: zhaow@bcm.edu.

المصدر: Structure (London, England : 1993) [Structure] 2024 Jul 11; Vol. 32 (7), pp. 899-906.e3. Date of Electronic Publication: 2024 Apr 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101087697 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-4186 (Electronic) Linking ISSN: 09692126 NLM ISO Abbreviation: Structure Subsets: MEDLINE

مواضيع طبية MeSH: Cryoelectron Microscopy* , Platelet Glycoprotein GPIIb-IIIa Complex*/metabolism , Platelet Glycoprotein GPIIb-IIIa Complex*/chemistry, Humans ; Binding Sites ; Manganese/metabolism ; Manganese/chemistry ; Models, Molecular ; Protein Binding ; Protein Conformation ; Protein Multimerization ; Integrin beta3/chemistry ; Integrin alpha2/chemistry

المؤلفون: Coffman RE; Scientific Computing and Imaging Institute, University of Utah, Salt Lake City, UT 84112, USA., Bidone TC; Scientific Computing and Imaging Institute, University of Utah, Salt Lake City, UT 84112, USA.; Department of Biomedical Engineering, University of Utah, Salt Lake City, UT 84112, USA.; Department of Biochemistry, University of Utah, Salt Lake City, UT 84112, USA.; Department of Molecular Pharmaceutics, University of Utah, Salt Lake City, UT 84112, USA.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 Jun 14; Vol. 25 (12). Date of Electronic Publication: 2024 Jun 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Oligopeptides*/chemistry , Oligopeptides*/metabolism , Platelet Glycoprotein GPIIb-IIIa Complex*/metabolism , Platelet Glycoprotein GPIIb-IIIa Complex*/chemistry , Protein Binding* , Molecular Dynamics Simulation*, Humans ; Blood Platelets/metabolism ; Binding Sites ; Integrin beta3/metabolism ; Integrin beta3/chemistry

المؤلفون: Wang R; School of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen, Guangdong Province, China.; Guangdong Engineering Technology Center of Nutrition Transformation, Sun Yat-sen University, Shenzhen, Guangdong Province, China.; Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Sun Yat-sen University, Guangzhou, Guangdong Province, China., Tian Z; School of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen, Guangdong Province, China.; Guangdong Engineering Technology Center of Nutrition Transformation, Sun Yat-sen University, Shenzhen, Guangdong Province, China.; Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Sun Yat-sen University, Guangzhou, Guangdong Province, China., Wang C; School of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen, Guangdong Province, China.; Guangdong Engineering Technology Center of Nutrition Transformation, Sun Yat-sen University, Shenzhen, Guangdong Province, China.; Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Sun Yat-sen University, Guangzhou, Guangdong Province, China., Zhang B; School of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen, Guangdong Province, China., Zhu M; School of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen, Guangdong Province, China., Yang Y; School of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen, Guangdong Province, China.; Guangdong Engineering Technology Center of Nutrition Transformation, Sun Yat-sen University, Shenzhen, Guangdong Province, China.; Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Sun Yat-sen University, Guangzhou, Guangdong Province, China.

المصدر: Cell biochemistry and function [Cell Biochem Funct] 2024 Jun; Vol. 42 (4), pp. e4039.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 8305874 Publication Model: Print Cited Medium: Internet ISSN: 1099-0844 (Electronic) Linking ISSN: 02636484 NLM ISO Abbreviation: Cell Biochem Funct Subsets: MEDLINE

مواضيع طبية MeSH: Platelet Aggregation*/drug effects , Platelet Glycoprotein GPIIb-IIIa Complex*/metabolism , Platelet Glycoprotein GPIIb-IIIa Complex*/antagonists & inhibitors , Spike Glycoprotein, Coronavirus*/metabolism , Signal Transduction*/drug effects, Humans ; SARS-CoV-2/drug effects ; COVID-19/metabolism ; Blood Platelets/metabolism ; Blood Platelets/drug effects ; Calcitriol/pharmacology ; src-Family Kinases/metabolism ; src-Family Kinases/antagonists & inhibitors ; Syk Kinase/metabolism ; Syk Kinase/antagonists & inhibitors ; Phosphorylation/drug effects ; COVID-19 Drug Treatment

المؤلفون: Han X; Case Western Reserve University School of Medicine, Department of Pharmacology, Cleveland, Ohio, USA., Knauss EA; Case Western Reserve University School of Medicine, Department of Pharmacology, Cleveland, Ohio, USA., Fuente M; Case Western Reserve University School of Medicine, Department of Pharmacology, Cleveland, Ohio, USA., Li W; Department of Biomedical Sciences, Joan C. Edwards School of Medicine at Marshall University, Huntington, West Virginia, USA., Conlon RA; Case Transgenic and Targeting Facility, Case Western Reserve University, Cleveland, Ohio, USA., LePage DF; Case Transgenic and Targeting Facility, Case Western Reserve University, Cleveland, Ohio, USA., Jiang W; Case Transgenic and Targeting Facility, Case Western Reserve University, Cleveland, Ohio, USA., Renna SA; Department of Medicine, The Cardeza Foundation for Hematologic Research, Thomas Jefferson University, Philadelphia, Pennsylvania, USA., McKenzie SE; Department of Medicine, The Cardeza Foundation for Hematologic Research, Thomas Jefferson University, Philadelphia, Pennsylvania, USA., Nieman MT; Case Western Reserve University School of Medicine, Department of Pharmacology, Cleveland, Ohio, USA. Electronic address: marvin.nieman@case.edu.

المصدر: Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2024 Jun; Vol. 22 (6), pp. 1715-1726. Date of Electronic Publication: 2024 Mar 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 101170508 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7836 (Electronic) Linking ISSN: 15387836 NLM ISO Abbreviation: J Thromb Haemost Subsets: MEDLINE

مواضيع طبية MeSH: Blood Platelets*/metabolism , Receptors, Thrombin*/genetics , Receptors, Thrombin*/metabolism , Thrombin*/metabolism , Platelet Aggregation* , Platelet Glycoprotein GPIIb-IIIa Complex*/metabolism , Platelet Glycoprotein GPIIb-IIIa Complex*/genetics , Mice, Inbred C57BL*, Animals ; Disease Models, Animal ; Crotalid Venoms/pharmacology ; Crotalid Venoms/toxicity ; Adenosine Diphosphate/metabolism ; Adenosine Diphosphate/pharmacology ; P-Selectin/metabolism ; P-Selectin/genetics ; Point Mutation ; Gene Knock-In Techniques ; Signal Transduction ; Thrombosis/genetics ; Thrombosis/blood ; Male ; Chlorides ; Mice ; Platelet Activation ; CRISPR-Cas Systems ; Humans ; Phenotype ; Ferric Compounds ; Oligopeptides ; Lectins, C-Type ; Receptors, Proteinase-Activated

المؤلفون: Bruno F; Royal Brompton & Harefield Hospitals, Imperial College and King's College, Sydney Street, London SW3 6NP, UK.; Division of Cardiology, Cardiovascular and Thoracic Department, Città della Salute e della Scienza, Turin 10126, Italy; Cardiology, Department of Medical Sciences, University of Turin, Italy., Wenzl FA; Center for Molecular Cardiology, University of Zurich, Zurich, Switzerland., De Filippo O; Division of Cardiology, Cardiovascular and Thoracic Department, Città della Salute e della Scienza, Turin 10126, Italy; Cardiology, Department of Medical Sciences, University of Turin, Italy., Kraler S; Center for Molecular Cardiology, University of Zurich, Zurich, Switzerland.; Department of Internal Medicine, Cantonal Hospital of Baden, Baden, Switzerland., Giacobbe F; Division of Cardiology, Cardiovascular and Thoracic Department, Città della Salute e della Scienza, Turin 10126, Italy; Cardiology, Department of Medical Sciences, University of Turin, Italy., Roffi M; Division of Cardiology, Department of Medicine, Geneva University Hospitals, 1205 Geneva, Switzerland., Muller O; Department of Cardiology, University Hospital of Lausanne, 1011 Lausanne, Switzerland., Räber L; Department of Cardiology, Bern University Hospital, University of Bern, 3010 Bern, Switzerland., Templin C; Department of Cardiology, University Heart Center, University Hospital Zurich, 8091 Zurich, Switzerland., De Ferrari GM; Division of Cardiology, Cardiovascular and Thoracic Department, Città della Salute e della Scienza, Turin 10126, Italy; Cardiology, Department of Medical Sciences, University of Turin, Italy., D'Ascenzo F; Division of Cardiology, Cardiovascular and Thoracic Department, Città della Salute e della Scienza, Turin 10126, Italy; Cardiology, Department of Medical Sciences, University of Turin, Italy., Lüscher TF; Royal Brompton & Harefield Hospitals, Imperial College and King's College, Sydney Street, London SW3 6NP, UK.; Center for Molecular Cardiology, University of Zurich, Zurich, Switzerland.

مؤلفون مشاركون: SPUM-ACS investigators

المصدر: European heart journal. Cardiovascular pharmacotherapy [Eur Heart J Cardiovasc Pharmacother] 2024 Aug 14; Vol. 10 (5), pp. 391-402.

نوع المنشور: Journal Article; Multicenter Study; Observational Study

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 101669491 Publication Model: Print Cited Medium: Internet ISSN: 2055-6845 (Electronic) NLM ISO Abbreviation: Eur Heart J Cardiovasc Pharmacother Subsets: MEDLINE

مواضيع طبية MeSH: Acute Coronary Syndrome*/mortality , Acute Coronary Syndrome*/therapy , Acute Coronary Syndrome*/drug therapy , Acute Coronary Syndrome*/diagnosis , Platelet Glycoprotein GPIIb-IIIa Complex*/antagonists & inhibitors , Platelet Aggregation Inhibitors*/adverse effects , Platelet Aggregation Inhibitors*/therapeutic use , Hemorrhage*/chemically induced , Hemorrhage*/epidemiology , Percutaneous Coronary Intervention*/adverse effects , Percutaneous Coronary Intervention*/mortality, Humans ; Male ; Female ; Aged ; Prospective Studies ; Middle Aged ; Treatment Outcome ; Risk Factors ; Time Factors ; Risk Assessment ; Purinergic P2Y Receptor Antagonists/adverse effects ; Purinergic P2Y Receptor Antagonists/therapeutic use ; Purinergic P2Y Receptor Antagonists/administration & dosage

المؤلفون: Xu D; Department of Emergency Medicine, The First Hospital of Jiaxing, Jiaxing University, Jiaxing, China., Yang C; Department of Emergency Medicine, The First Hospital of Jiaxing, Jiaxing University, Jiaxing, China., Cao W; Department of Emergency Medicine, The First Hospital of Jiaxing, Jiaxing University, Jiaxing, China., Zhang X; Department of Emergency Medicine, The First Hospital of Jiaxing, Jiaxing University, Jiaxing, China., Yang S; Department of Emergency Medicine, The First Hospital of Jiaxing, Jiaxing University, Jiaxing, China., Shen X; Department of Emergency Medicine, The First Hospital of Jiaxing, Jiaxing University, Jiaxing, China., Xu J; Department of Emergency Medicine, The First Hospital of Jiaxing, Jiaxing University, Jiaxing, China., Yu H; Department of Emergency Medicine, The First Hospital of Jiaxing, Jiaxing University, Jiaxing, China.

المصدر: Pharmacotherapy [Pharmacotherapy] 2024 Aug; Vol. 44 (8), pp. 675-691. Date of Electronic Publication: 2024 Jul 01.

نوع المنشور: Meta-Analysis; Journal Article; Review

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 8111305 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-9114 (Electronic) Linking ISSN: 02770008 NLM ISO Abbreviation: Pharmacotherapy Subsets: MEDLINE

مواضيع طبية MeSH: Ischemic Stroke*/drug therapy , Platelet Glycoprotein GPIIb-IIIa Complex*/antagonists & inhibitors , Platelet Aggregation Inhibitors*/therapeutic use , Platelet Aggregation Inhibitors*/adverse effects , Platelet Aggregation Inhibitors*/administration & dosage, Humans ; Randomized Controlled Trials as Topic

المؤلفون: Zhu Z; Modern Research Center for Traditional Chinese Medicine, Beijing Research Institute of Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China., Luo Y; Modern Research Center for Traditional Chinese Medicine, Beijing Research Institute of Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China., Liao H; Modern Research Center for Traditional Chinese Medicine, Beijing Research Institute of Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China., Guo R; Modern Research Center for Traditional Chinese Medicine, Beijing Research Institute of Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China., Hao D; Modern Research Center for Traditional Chinese Medicine, Beijing Research Institute of Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China., Lu Z; Modern Research Center for Traditional Chinese Medicine, Beijing Research Institute of Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China., Huang M; Modern Research Center for Traditional Chinese Medicine, Beijing Research Institute of Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China., Sun C; State Key Laboratory of Integration and Innovation of Classic Formula and Modern Chinese Medicine, Lunan Pharmaceutical Group Co. Ltd., Linyi City, Shandong Province, China., Yao J; State Key Laboratory of Integration and Innovation of Classic Formula and Modern Chinese Medicine, Lunan Pharmaceutical Group Co. Ltd., Linyi City, Shandong Province, China., Wei N; Department of Oncology and Cancer Therapeutics Program, Montefiore Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, New York, United States., Zeng K; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China., Tu P; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China., Zhang G; State Key Laboratory of Integration and Innovation of Classic Formula and Modern Chinese Medicine, Lunan Pharmaceutical Group Co. Ltd., Linyi City, Shandong Province, China.

المصدر: Thrombosis and haemostasis [Thromb Haemost] 2024 Aug; Vol. 124 (8), pp. 753-769. Date of Electronic Publication: 2024 Jan 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Thieme Country of Publication: Germany NLM ID: 7608063 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2567-689X (Electronic) Linking ISSN: 03406245 NLM ISO Abbreviation: Thromb Haemost Subsets: MEDLINE

مواضيع طبية MeSH: Phospholipase C gamma*/metabolism , Signal Transduction*/drug effects , Thromboxane A2*/metabolism , Platelet Activation*/drug effects , Hemostasis*/drug effects , Thrombin*/metabolism , Blood Platelets*/metabolism , Blood Platelets*/drug effects , Protein Kinase C*/metabolism , Flavonoids*/pharmacology , Platelet Aggregation*/drug effects , Platelet Glycoprotein GPIIb-IIIa Complex*/metabolism, Animals ; Mice ; Humans ; Male ; Mice, Inbred C57BL ; Hemorrhage/chemically induced ; Hemorrhage/drug therapy ; Bleeding Time