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المؤلفون: Chris De Savi, Celina D'Cruz, Anne Marie Mazzola, Ermira Pazolli, Brendon Ladd, Graham Richmond, Claire Sadler, Steve Powell, Rachel Rowlinson, Zena Wilson, Graeme E. Walker, Gareth Davies, Michael Tonge, Stuart E. Pearson, Richard A. Norman, Thomas Moss, Philip MacFaul, Galith Karoutchi, Lyman J.L. Feron, Craig S. Donald, Michael Hulse, Peter Ballard, Camila de Almeida, Jon O. Curwen, Rowena J. Callis, David Buttar, Alfred A. Rabow, Mandy Lawson, Robert H. Bradbury, Hazel M. Weir
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f2ea8b1988f522a97b4476bc1bfb489
https://doi.org/10.1158/0008-5472.22409537.v1 -
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المؤلفون: Chris De Savi, Celina D'Cruz, Anne Marie Mazzola, Ermira Pazolli, Brendon Ladd, Graham Richmond, Claire Sadler, Steve Powell, Rachel Rowlinson, Zena Wilson, Graeme E. Walker, Gareth Davies, Michael Tonge, Stuart E. Pearson, Richard A. Norman, Thomas Moss, Philip MacFaul, Galith Karoutchi, Lyman J.L. Feron, Craig S. Donald, Michael Hulse, Peter Ballard, Camila de Almeida, Jon O. Curwen, Rowena J. Callis, David Buttar, Alfred A. Rabow, Mandy Lawson, Robert H. Bradbury, Hazel M. Weir
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14c5919450d0037769dc8885c171e5d8
https://doi.org/10.1158/0008-5472.22409534.v1 -
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المؤلفون: Chris De Savi, Celina D'Cruz, Anne Marie Mazzola, Ermira Pazolli, Brendon Ladd, Graham Richmond, Claire Sadler, Steve Powell, Rachel Rowlinson, Zena Wilson, Graeme E. Walker, Gareth Davies, Michael Tonge, Stuart E. Pearson, Richard A. Norman, Thomas Moss, Philip MacFaul, Galith Karoutchi, Lyman J.L. Feron, Craig S. Donald, Michael Hulse, Peter Ballard, Camila de Almeida, Jon O. Curwen, Rowena J. Callis, David Buttar, Alfred A. Rabow, Mandy Lawson, Robert H. Bradbury, Hazel M. Weir
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::121cf8596ca6963e592f8c1559e47fd8
https://doi.org/10.1158/0008-5472.c.6507809.v1 -
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المؤلفون: Chris De Savi, Celina D'Cruz, Anne Marie Mazzola, Ermira Pazolli, Brendon Ladd, Graham Richmond, Claire Sadler, Steve Powell, Rachel Rowlinson, Zena Wilson, Graeme E. Walker, Gareth Davies, Michael Tonge, Stuart E. Pearson, Richard A. Norman, Thomas Moss, Philip MacFaul, Galith Karoutchi, Lyman J.L. Feron, Craig S. Donald, Michael Hulse, Peter Ballard, Camila de Almeida, Jon O. Curwen, Rowena J. Callis, David Buttar, Alfred A. Rabow, Mandy Lawson, Robert H. Bradbury, Hazel M. Weir
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc4d27d54650a74388b4e3bbd209d6f
https://doi.org/10.1158/0008-5472.22409528 -
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المؤلفون: Chris De Savi, Celina D'Cruz, Anne Marie Mazzola, Ermira Pazolli, Brendon Ladd, Graham Richmond, Claire Sadler, Steve Powell, Rachel Rowlinson, Zena Wilson, Graeme E. Walker, Gareth Davies, Michael Tonge, Stuart E. Pearson, Richard A. Norman, Thomas Moss, Philip MacFaul, Galith Karoutchi, Lyman J.L. Feron, Craig S. Donald, Michael Hulse, Peter Ballard, Camila de Almeida, Jon O. Curwen, Rowena J. Callis, David Buttar, Alfred A. Rabow, Mandy Lawson, Robert H. Bradbury, Hazel M. Weir
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::500fb6b45ef15b3a4c16d2efaec374bf
https://doi.org/10.1158/0008-5472.22409531 -
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المؤلفون: Craig S. Donald, Galith Karoutchi, Syeed Hussain, Peter Ballard, Gordon S. Currie, Barry R. Hayter, Hazel M. Weir, H. Gingell, Richard A. Norman, Steven C. Glossop, David Buttar, Lyman Feron, Zena Wilson, Stuart E. Pearson, Camila de Almeida, Christopher D. Davies, Rowena Callis, Philip A. MacFaul, Thomas A. Moss, Chris De Savi, Alfred A. Rabow, David M. Andrews, Graeme Walker, Michael Tonge, Scott G. Lamont, Jon Curwen, Robert Hugh Bradbury
المصدر: Journal of Medicinal Chemistry. 58:8128-8140
مصطلحات موضوعية: Indole test, Fulvestrant, Ligand, Stereochemistry, Antagonist, Estrogen receptor, Bioavailability, chemistry.chemical_compound, chemistry, Drug Discovery, medicine, Molecular Medicine, Potency, Acrylic acid, medicine.drug
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المؤلفون: Andrew David Morley, Galith Karoutchi, Stefan Gerhardt, Attilla Ting, Chris De Savi, Nash Ian Alun, Ken Page
المصدر: Bioorganic & Medicinal Chemistry Letters. 22:271-277
مصطلحات موضوعية: Models, Molecular, Zinc binding, Matrix metalloproteinase inhibitor, Chemistry, Pharmaceutical, Clinical Biochemistry, Pharmaceutical Science, Matrix Metalloproteinase Inhibitors, Biochemistry, Inhibitory Concentration 50, Structure-Activity Relationship, Dogs, Matrix Metalloproteinase 13, Osteoarthritis, Drug Discovery, Animals, Humans, Structure–activity relationship, Potency, Enzyme Inhibitors, Lead (electronics), Molecular Biology, Chemistry, Organic Chemistry, Dosing regimen, Combinatorial chemistry, Rats, Bioavailability, Zinc, Models, Chemical, Solubility, Drug Design, Molecular Medicine, Selectivity
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المؤلفون: Michael James, Gordon A. Hamlin, Stefan Gerhardt, David Ryan, Nash Ian Alun, Attilla Ting, Stephen J. Norris, Galith Karoutchi, Chris De Savi, Neil Rankine, David J. Hargreaves, Christine M. Wood, Sarah V. Baker, Philip A. MacFaul, Andrew David Morley, Kostas Karabelas
المصدر: Bioorganic & Medicinal Chemistry Letters. 21:4215-4219
مصطلحات موضوعية: Molecular model, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Stereoisomerism, Carboxamide, Matrix Metalloproteinase Inhibitors, Crystallography, X-Ray, Biochemistry, Structure-Activity Relationship, Catalytic Domain, Matrix Metalloproteinase 13, Drug Discovery, Hydrolase, medicine, Structure–activity relationship, Protease Inhibitors, Binding site, Molecular Biology, Binding Sites, biology, Chemistry, Organic Chemistry, Zinc, Enzyme inhibitor, biology.protein, Molecular Medicine, Selectivity
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المؤلفون: Stefan Gerhardt, Andrew David Morley, Peter W. Kenny, Hannes Simader, Emma V. Jones, Galith Karoutchi, Stephan Krapp, Neil Rankine, Keith Oldham, Paul A. Bethel, Stefan Steinbacher, Martin Augustin
المصدر: Bioorganic & Medicinal Chemistry Letters. 19:4622-4625
مصطلحات موضوعية: Cathepsin, biology, Chemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Crystallography, X-Ray, Cathepsins, Biochemistry, Cathepsin B, Cathepsin L, Structure-Activity Relationship, Molecular recognition, Drug Design, Drug Discovery, Cathepsin L2, Cathepsin K, biology.protein, Molecular Medicine, Computer Simulation, Protease Inhibitors, Cathepsin V, Molecular Biology, Cathepsin S
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المؤلفون: Neil Rankine, Linda J. Wood, Galith Karoutchi, Michelle Coulson, Keith Oldham, Emma V. Jones, Paul A. Bethel, Stephan Krapp, Susannah J. Ford, Stefan Gerhardt, David Ryan, Matthew Grist, Peter W. Kenny, Hannes Simader, Andrew David Morley, Stuart L. Wells, Gordon A. Hamlin, Stefan Steinbacher, Jack E. Dawson, Nabil Asaad, Martin Augustin, Michael James
المصدر: Bioorganic & Medicinal Chemistry Letters. 19:4280-4283
مصطلحات موضوعية: Cartilage, Articular, Stereochemistry, Cathepsin L, Chemistry, Pharmaceutical, Clinical Biochemistry, Pharmaceutical Science, Mice, Transgenic, Crystallography, X-Ray, Ligands, Biochemistry, Catalysis, Cathepsin B, Mice, Structure-Activity Relationship, Cathepsin O, Nitriles, Drug Discovery, Cathepsin L2, Cathepsin K, Animals, Humans, Cathepsin V, skin and connective tissue diseases, Molecular Biology, Cathepsin S, Cathepsin, biology, Chemistry, fungi, Organic Chemistry, Proteins, body regions, Drug Design, biology.protein, Molecular Medicine, Peptides