المؤلفون: Singh K; MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK., Lau CK; MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK., Manigrasso G; MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK., Gama JB; Instituto de Investigação e Inovação em Saúde (i3S)/Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, 4200-135 Porto, Portugal., Gassmann R; Instituto de Investigação e Inovação em Saúde (i3S)/Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, 4200-135 Porto, Portugal., Carter AP; MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK.

المصدر: Science (New York, N.Y.) [Science] 2024 Mar 29; Vol. 383 (6690), pp. eadk8544. Date of Electronic Publication: 2024 Mar 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Dynactin Complex*/chemistry , Dynactin Complex*/genetics , Dynactin Complex*/metabolism , Dyneins*/chemistry , Dyneins*/genetics , Dyneins*/metabolism , Microtubule-Associated Proteins*/chemistry , Microtubule-Associated Proteins*/metabolism , 1-Alkyl-2-acetylglycerophosphocholine Esterase* , Nerve Tissue Proteins*/chemistry , Nerve Tissue Proteins*/metabolism , Adaptor Proteins, Signal Transducing*/chemistry , Adaptor Proteins, Signal Transducing*/metabolism, Cryoelectron Microscopy ; Microtubules/metabolism ; Protein Binding ; Humans ; HeLa Cells ; WD40 Repeats ; Protein Interaction Mapping

المؤلفون: Celestino R; Instituto de Investigação e Inovação em Saúde-i3S, Universidade do Porto, Porto, Portugal., Gama JB; Instituto de Investigação e Inovação em Saúde-i3S, Universidade do Porto, Porto, Portugal., Castro-Rodrigues AF; Instituto de Investigação e Inovação em Saúde-i3S, Universidade do Porto, Porto, Portugal., Barbosa DJ; Instituto de Investigação e Inovação em Saúde-i3S, Universidade do Porto, Porto, Portugal.; TOXRUN-Toxicology Research Unit, University Institute of Health Sciences, Advanced Polytechnic and University Cooperative (CESPU), Cooperative of Limited Liability (CRL), Gandra, Portugal., Rocha H; Instituto de Investigação e Inovação em Saúde-i3S, Universidade do Porto, Porto, Portugal., d'Amico EA; Department of Mechanistic Cell Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany., Musacchio A; Department of Mechanistic Cell Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany.; Centre for Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Essen, Germany., Carvalho AX; Instituto de Investigação e Inovação em Saúde-i3S, Universidade do Porto, Porto, Portugal., Morais-Cabral JH; Instituto de Investigação e Inovação em Saúde-i3S, Universidade do Porto, Porto, Portugal., Gassmann R; Instituto de Investigação e Inovação em Saúde-i3S, Universidade do Porto, Porto, Portugal.

المصدر: The Journal of cell biology [J Cell Biol] 2022 Aug 01; Vol. 221 (8). Date of Electronic Publication: 2022 Jul 13.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 0375356 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-8140 (Electronic) Linking ISSN: 00219525 NLM ISO Abbreviation: J Cell Biol Subsets: MEDLINE

مواضيع طبية MeSH: Adaptor Proteins, Signal Transducing*/genetics , Adaptor Proteins, Signal Transducing*/metabolism , Cytoplasmic Dyneins*/genetics , Cytoplasmic Dyneins*/metabolism , Kinesins*/genetics , Nerve Tissue Proteins*/genetics , Nerve Tissue Proteins*/metabolism , Organelles*/metabolism, Animals ; Caenorhabditis elegans/genetics ; Caenorhabditis elegans/metabolism ; Humans ; Sensory Receptor Cells/metabolism

المؤلفون: Celestino R; Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, Porto, Portugal.; Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal., Henen MA; Department of Biochemistry and Molecular Genetics, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America.; Faculty of Pharmacy, Mansoura University, Mansoura, Egypt., Gama JB; Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, Porto, Portugal.; Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal., Carvalho C; Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, Porto, Portugal.; Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal., McCabe M; Department of Biochemistry and Molecular Genetics, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America., Barbosa DJ; Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, Porto, Portugal.; Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal., Born A; Department of Biochemistry and Molecular Genetics, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America., Nichols PJ; Department of Biochemistry and Molecular Genetics, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America., Carvalho AX; Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, Porto, Portugal.; Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal., Gassmann R; Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, Porto, Portugal.; Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal., Vögeli B; Department of Biochemistry and Molecular Genetics, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America.

المصدر: PLoS biology [PLoS Biol] 2019 Jan 07; Vol. 17 (1), pp. e3000100. Date of Electronic Publication: 2019 Jan 07 (Print Publication: 2019).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE

مواضيع طبية MeSH: Cytoplasmic Dyneins/*genetics , Cytoplasmic Dyneins/*metabolism , Dyneins/*genetics, Adaptor Proteins, Signal Transducing/metabolism ; Animals ; Caenorhabditis elegans/genetics ; Caenorhabditis elegans Proteins/genetics ; Caenorhabditis elegans Proteins/metabolism ; Carrier Proteins/metabolism ; Conserved Sequence ; Dynactin Complex ; Dyneins/metabolism ; HeLa Cells ; Humans ; Lysosomes/metabolism ; Microtubule-Associated Proteins/metabolism ; Microtubules/metabolism ; Nuclear Magnetic Resonance, Biomolecular/methods ; Protein Binding/physiology ; Protein Transport/genetics ; Protein Transport/physiology ; Spindle Apparatus

المؤلفون: Pereira C; Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, 4200-135 Porto, Portugal; Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, 4200-135 Porto, Portugal., Reis RM; Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, 4200-135 Porto, Portugal; Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, 4200-135 Porto, Portugal., Gama JB; Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, 4200-135 Porto, Portugal; Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, 4200-135 Porto, Portugal., Celestino R; Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, 4200-135 Porto, Portugal; Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, 4200-135 Porto, Portugal., Cheerambathur DK; Ludwig Institute for Cancer Research, Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA 92093, USA., Carvalho AX; Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, 4200-135 Porto, Portugal; Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, 4200-135 Porto, Portugal., Gassmann R; Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, 4200-135 Porto, Portugal; Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, 4200-135 Porto, Portugal. Electronic address: rgassmann@ibmc.up.pt.

المصدر: Current biology : CB [Curr Biol] 2018 Nov 05; Vol. 28 (21), pp. 3408-3421.e8. Date of Electronic Publication: 2018 Oct 25.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: England NLM ID: 9107782 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0445 (Electronic) Linking ISSN: 09609822 NLM ISO Abbreviation: Curr Biol Subsets: MEDLINE

مواضيع طبية MeSH: Caenorhabditis elegans/*metabolism , Kinetochores/*metabolism , Microtubules/*metabolism, Animals ; Caenorhabditis elegans/embryology ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; Dyneins/metabolism ; Humans ; Mad2 Proteins/genetics ; Mad2 Proteins/metabolism ; Nuclear Proteins/genetics ; Nuclear Proteins/metabolism

المؤلفون: Gama JB; Instituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135 Porto, Portugal.; Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135 Porto, Portugal., Pereira C; Instituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135 Porto, Portugal.; Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135 Porto, Portugal., Simões PA; Instituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135 Porto, Portugal.; Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135 Porto, Portugal., Celestino R; Instituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135 Porto, Portugal.; Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135 Porto, Portugal., Reis RM; Instituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135 Porto, Portugal.; Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135 Porto, Portugal., Barbosa DJ; Instituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135 Porto, Portugal.; Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135 Porto, Portugal., Pires HR; Instituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135 Porto, Portugal.; Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135 Porto, Portugal., Carvalho C; Instituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135 Porto, Portugal.; Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135 Porto, Portugal., Amorim J; Instituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135 Porto, Portugal.; Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135 Porto, Portugal., Carvalho AX; Instituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135 Porto, Portugal.; Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135 Porto, Portugal., Cheerambathur DK; Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA 92093.; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093., Gassmann R; Instituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135 Porto, Portugal rgassmann@ibmc.up.pt.; Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135 Porto, Portugal.

المصدر: The Journal of cell biology [J Cell Biol] 2017 Apr 03; Vol. 216 (4), pp. 943-960. Date of Electronic Publication: 2017 Mar 20.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 0375356 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-8140 (Electronic) Linking ISSN: 00219525 NLM ISO Abbreviation: J Cell Biol Subsets: MEDLINE

مواضيع طبية MeSH: Chromosomal Proteins, Non-Histone/*metabolism , Dyneins/*metabolism , Kinetochores/*metabolism , Microtubule-Associated Proteins/*metabolism , Spindle Apparatus/*metabolism, Animals ; Caenorhabditis elegans/metabolism ; Caenorhabditis elegans/physiology ; Carrier Proteins/metabolism ; Cell Cycle Proteins/metabolism ; Cell Line, Tumor ; Chromosome Segregation/physiology ; Dynactin Complex/metabolism ; HeLa Cells ; Humans ; Kinetochores/physiology ; Microtubules/metabolism ; Microtubules/physiology ; Mitosis/physiology ; Spindle Apparatus/physiology

المؤلفون: Cruz A; Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho , Braga , Portugal ; ICVS/3B's - PT Government Associate Laboratory, University of Minho , Braga , Portugal., Ludovico P; Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho , Braga , Portugal ; ICVS/3B's - PT Government Associate Laboratory, University of Minho , Braga , Portugal., Torrado E; Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho , Braga , Portugal ; ICVS/3B's - PT Government Associate Laboratory, University of Minho , Braga , Portugal ; Trudeau Institute , Saranac Lake, NY , USA., Gama JB; Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho , Braga , Portugal ; ICVS/3B's - PT Government Associate Laboratory, University of Minho , Braga , Portugal., Sousa J; Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho , Braga , Portugal ; ICVS/3B's - PT Government Associate Laboratory, University of Minho , Braga , Portugal., Gaifem J; Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho , Braga , Portugal ; ICVS/3B's - PT Government Associate Laboratory, University of Minho , Braga , Portugal., Appelberg R; Department of Immunophysiology, University of Porto , Porto , Portugal., Rodrigues F; Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho , Braga , Portugal ; ICVS/3B's - PT Government Associate Laboratory, University of Minho , Braga , Portugal., Cooper AM; Trudeau Institute , Saranac Lake, NY , USA., Pedrosa J; Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho , Braga , Portugal ; ICVS/3B's - PT Government Associate Laboratory, University of Minho , Braga , Portugal., Saraiva M; Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho , Braga , Portugal ; ICVS/3B's - PT Government Associate Laboratory, University of Minho , Braga , Portugal., Castro AG; Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho , Braga , Portugal ; ICVS/3B's - PT Government Associate Laboratory, University of Minho , Braga , Portugal.

المصدر: Frontiers in immunology [Front Immunol] 2015 Sep 30; Vol. 6, pp. 498. Date of Electronic Publication: 2015 Sep 30 (Print Publication: 2015).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Print ISSN: 1664-3224 (Print) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: PubMed not MEDLINE

المؤلفون: Gama JB; Life and Health Sciences Research Institute, School of Health Sciences, University of Minho, Braga, Portugal; ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal., Ohlmeier S; Proteomics Core Facility, Biocenter Oulu, Department of Biochemistry, University of Oulu, Oulu, Finland., Martins TG; Life and Health Sciences Research Institute, School of Health Sciences, University of Minho, Braga, Portugal; ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal., Fraga AG; Life and Health Sciences Research Institute, School of Health Sciences, University of Minho, Braga, Portugal; ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal., Sampaio-Marques B; Life and Health Sciences Research Institute, School of Health Sciences, University of Minho, Braga, Portugal; ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal., Carvalho MA; Chemistry Research Center, School of Sciences, University of Minho, Braga, Portugal., Proença F; Chemistry Research Center, School of Sciences, University of Minho, Braga, Portugal., Silva MT; Institute for Molecular and Cell Biology, Porto, Portugal., Pedrosa J; Life and Health Sciences Research Institute, School of Health Sciences, University of Minho, Braga, Portugal; ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal., Ludovico P; Life and Health Sciences Research Institute, School of Health Sciences, University of Minho, Braga, Portugal; ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal.

المصدر: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2014 Aug 07; Vol. 8 (8), pp. e3066. Date of Electronic Publication: 2014 Aug 07 (Print Publication: 2014).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE

مواضيع طبية MeSH: Collagen/*biosynthesis , Cytoskeleton/*drug effects , Macrolides/*toxicity , Mycobacterium ulcerans/*pathogenicity , Proteomics/*methods, Animals ; Autophagy/drug effects ; Bacterial Toxins/metabolism ; Cells, Cultured ; Cytoskeleton/chemistry ; Cytoskeleton/physiology ; Mice

المؤلفون: Name KP; Programa de Pós Graduação em Biologia Animal, Instituto de Ciências Biológicas, Universidade de Brasília, Distrito Federal, Brazil., Barros-Cordeiro KB, Filho JB, Wolff M, Pujol-Luz JR, Báo SN

المصدر: Journal of morphology [J Morphol] 2012 Feb; Vol. 273 (2), pp. 160-72. Date of Electronic Publication: 2011 Sep 28.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 0406125 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4687 (Electronic) Linking ISSN: 00222887 NLM ISO Abbreviation: J Morphol Subsets: MEDLINE

مواضيع طبية MeSH: Diptera/*ultrastructure, Acrosome/ultrastructure ; Animals ; Axoneme ; Cell Nucleus/ultrastructure ; Centrioles/ultrastructure ; Ejaculatory Ducts/ultrastructure ; Genitalia, Male/ultrastructure ; Male ; Microscopy, Electron, Transmission ; Mitochondria/ultrastructure ; Seminal Vesicles/ultrastructure ; Species Specificity ; Spermatogenesis/physiology ; Spermatozoa/ultrastructure ; Testis/ultrastructure ; Vas Deferens/ultrastructure

المؤلفون: Martins TG; Life and Health Sciences Research Institute, School of Health Sciences, University of Minho, Braga, Portugal., Trigo G, Fraga AG, Gama JB, Longatto-Filho A, Saraiva M, Silva MT, Castro AG, Pedrosa J

المصدر: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2012; Vol. 6 (11), pp. e1925. Date of Electronic Publication: 2012 Nov 29.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE

مواضيع طبية MeSH: Adrenal Cortex Hormones/*administration & dosage , Anti-Bacterial Agents/*administration & dosage , Buruli Ulcer/*drug therapy , Immunosuppressive Agents/*administration & dosage, Animals ; Buruli Ulcer/microbiology ; Buruli Ulcer/pathology ; Disease Models, Animal ; Female ; Foot/microbiology ; Foot/pathology ; Histocytochemistry ; Immunohistochemistry ; Mice ; Mice, Inbred BALB C ; Mycobacterium ulcerans/isolation & purification ; Rifampin/administration & dosage ; Streptomycin/pharmacology ; Treatment Outcome

المؤلفون: Martins TG; Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal., Gama JB, Fraga AG, Saraiva M, Silva MT, Castro AG, Pedrosa J

المصدر: PloS one [PLoS One] 2012; Vol. 7 (2), pp. e32740. Date of Electronic Publication: 2012 Feb 29.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Anti-Bacterial Agents/*therapeutic use , Buruli Ulcer/*drug therapy , Immunity, Cellular/*immunology , Mycobacterium ulcerans/*metabolism, Animals ; Dexamethasone/pharmacology ; Disease Models, Animal ; Disease Progression ; Drug Therapy, Combination/methods ; Female ; Flow Cytometry/methods ; Immunosuppressive Agents/therapeutic use ; Inflammation ; Lymphocytes/drug effects ; Mice ; Mice, Inbred BALB C ; Rifampin/administration & dosage ; Streptomycin/administration & dosage