المؤلفون: Goswami V; Department of Chemistry, Indian Institute of Technology Delhi, Hauz Khas, New Delhi 110016, India., Das SM; Department of Chemistry, Indian Institute of Technology Delhi, Hauz Khas, New Delhi 110016, India., Deep S; Department of Chemistry, Indian Institute of Technology Delhi, Hauz Khas, New Delhi 110016, India.

المصدر: Langmuir : the ACS journal of surfaces and colloids [Langmuir] 2024 Aug 06; Vol. 40 (31), pp. 16093-16102. Date of Electronic Publication: 2024 Jul 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9882736 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5827 (Electronic) Linking ISSN: 07437463 NLM ISO Abbreviation: Langmuir Subsets: MEDLINE

مواضيع طبية MeSH: Quercetin*/chemistry , Quercetin*/pharmacology , Copper*/chemistry , gamma-Crystallins*/chemistry , gamma-Crystallins*/metabolism , Protein Aggregates*/drug effects, Humans ; Drug Carriers/chemistry ; Nanoparticles/chemistry

المؤلفون: Guseman AJ; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., González JJ; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Yang D; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Gronenborn AM; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

المصدر: Protein science : a publication of the Protein Society [Protein Sci] 2024 Aug; Vol. 33 (8), pp. e5120.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9211750 Publication Model: Print Cited Medium: Internet ISSN: 1469-896X (Electronic) Linking ISSN: 09618368 NLM ISO Abbreviation: Protein Sci Subsets: MEDLINE

مواضيع طبية MeSH: gamma-Crystallins*/chemistry , gamma-Crystallins*/metabolism , gamma-Crystallins*/genetics , Asparagine*/chemistry , Asparagine*/metabolism , Aspartic Acid*/chemistry , Aspartic Acid*/metabolism , Protein Stability* , Molecular Dynamics Simulation*, Humans ; Nuclear Magnetic Resonance, Biomolecular ; Thermodynamics ; Cataract/metabolism ; Cataract/genetics ; Amino Acid Substitution

المؤلفون: Lin N; Eye Center of the Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou 310009, China; Institute of Translational Medicine, Zhejiang University School of Medicine, 268 Kaixuan Road, Hangzhou 310020, China., Song H; Department of Ophthalmology, Peking Union Medical College Hospital, No.1 Shuaifuyuan, Beijing 100730, China., Zhang Y; Eye Center of the Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou 310009, China; Institute of Translational Medicine, Zhejiang University School of Medicine, 268 Kaixuan Road, Hangzhou 310020, China., Chen F; Gansu Key Laboratory of Biomonitoring and Bioremediation for Environmental Pollution, School of Life Sciences, Lanzhou University, Lanzhou 730000, China., Xu J; Eye Center of the Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou 310009, China., Wu W; Eye Center of the Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou 310009, China., Tian Q; Eye Center of the Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou 310009, China; Institute of Translational Medicine, Zhejiang University School of Medicine, 268 Kaixuan Road, Hangzhou 310020, China., Luo C; Eye Center of the Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou 310009, China., Yao K; Eye Center of the Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou 310009, China., Hu L; The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, 3333 Binsheng Road, Hangzhou 310052, China. Electronic address: hulidan@zju.edu.cn., Chen X; Eye Center of the Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou 310009, China; Institute of Translational Medicine, Zhejiang University School of Medicine, 268 Kaixuan Road, Hangzhou 310020, China. Electronic address: chenxiangjun@zju.edu.cn.

المصدر: International journal of biological macromolecules [Int J Biol Macromol] 2024 Oct; Vol. 277 (Pt 2), pp. 134292. Date of Electronic Publication: 2024 Jul 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

مواضيع طبية MeSH: gamma-Crystallins*/genetics , gamma-Crystallins*/chemistry , gamma-Crystallins*/metabolism , Cataract*/genetics , Cataract*/metabolism , Protein Aggregates* , Protein Stability*, Humans ; HEK293 Cells ; Mutation ; Molecular Dynamics Simulation ; Protein Folding ; Protein Conformation ; Solubility ; Protein Aggregation, Pathological/genetics

المؤلفون: Kacirani A; Department of Chemical and Environmental Engineering, Yale University, New Haven, Connecticut 06520, United States.; Integrated Graduate Program in Physical and Engineering Biology, Yale University, New Haven, Connecticut 06520, United States., Uralcan B; Department of Chemical and Environmental Engineering, Yale University, New Haven, Connecticut 06520, United States.; Department of Chemical Engineering, Boğaziçi University, Istanbul 34342, Turkey., Domingues TS; Department of Chemical and Environmental Engineering, Yale University, New Haven, Connecticut 06520, United States.; Graduate Program in Applied Mathematics, Yale University, New Haven, Connecticut 06520, United States., Haji-Akbari A; Department of Chemical and Environmental Engineering, Yale University, New Haven, Connecticut 06520, United States.

المصدر: The journal of physical chemistry. B [J Phys Chem B] 2024 May 23; Vol. 128 (20), pp. 4931-4942. Date of Electronic Publication: 2024 Apr 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101157530 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5207 (Electronic) Linking ISSN: 15205207 NLM ISO Abbreviation: J Phys Chem B Subsets: MEDLINE

مواضيع طبية MeSH: Molecular Dynamics Simulation* , gamma-Crystallins*/chemistry , gamma-Crystallins*/metabolism , Pressure*, Humans ; Principal Component Analysis ; Protein Conformation ; Thermodynamics ; Protein Stability

المؤلفون: Serebryany E; Department of Physiology & Biophysics, Stony Brook University, SUNY, Stony Brook, NY 11794, USA.; Laufer Center for Physical & Quantitative Biology, Stony Brook University, SUNY, Stony Brook, NY 11794, USA., Martin RW; Department of Chemistry, UCI Irvine, Irvine, CA 92697-2025, USA.; Department of Molecular Biology & Biochemistry, UCI Irvine, Irvine, CA 92697-3900, USA., Takahashi GR; Department of Molecular Biology & Biochemistry, UCI Irvine, Irvine, CA 92697-3900, USA.

المصدر: Biomolecules [Biomolecules] 2024 May 17; Vol. 14 (5). Date of Electronic Publication: 2024 May 17.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X (Electronic) Linking ISSN: 2218273X NLM ISO Abbreviation: Biomolecules Subsets: MEDLINE

مواضيع طبية MeSH: gamma-Crystallins*/metabolism , gamma-Crystallins*/chemistry , gamma-Crystallins*/genetics , Cysteine*/metabolism , Cysteine*/chemistry , Lens, Crystalline*/metabolism , Lens, Crystalline*/chemistry, Humans ; Animals ; Cataract/metabolism

المؤلفون: Goswami V; Department of Chemistry, Indian Institute of Technology, Hauzkhas, Delhi New Delhi 110016, India., Tomar VR; Department of Chemistry, Indian Institute of Technology, Hauzkhas, Delhi New Delhi 110016, India., Yashika; Department of Chemistry, Indian Institute of Technology, Hauzkhas, Delhi New Delhi 110016, India., Deep S; Department of Chemistry, Indian Institute of Technology, Hauzkhas, Delhi New Delhi 110016, India.

المصدر: Langmuir : the ACS journal of surfaces and colloids [Langmuir] 2024 Mar 19; Vol. 40 (11), pp. 5617-5631. Date of Electronic Publication: 2023 Dec 05.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9882736 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5827 (Electronic) Linking ISSN: 07437463 NLM ISO Abbreviation: Langmuir Subsets: MEDLINE

مواضيع طبية MeSH: gamma-Crystallins* , Cataract* , Caffeic Acids*, Humans ; Ultraviolet Rays ; Quercetin

المؤلفون: Ghosh D; Department of Biological Sciences and Engineering, Indian Institute of Technology (IIT) Gandhinagar, Palaj, Gujarat 382355, India., Agarwal M; Computer Services Centre, Indian Institute of Technology (IIT) Delhi, Hauz Khas, New Delhi, Delhi 110016, India., Radhakrishna M; Department of Chemical Engineering, Indian Institute of Technology (IIT) Gandhinagar, Palaj, Gujarat 382355, India.; Center for Biomedical Engineering, Indian Institute of Technology (IIT) Gandhinagar, Palaj, Gujarat 382355, India.

المصدر: Journal of chemical theory and computation [J Chem Theory Comput] 2024 Feb 27; Vol. 20 (4), pp. 1740-1752. Date of Electronic Publication: 2023 Dec 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101232704 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-9626 (Electronic) Linking ISSN: 15499618 NLM ISO Abbreviation: J Chem Theory Comput Subsets: MEDLINE

مواضيع طبية MeSH: alpha-Crystallins*/metabolism , gamma-Crystallins*/chemistry , Cataract*/metabolism, Humans ; Molecular Docking Simulation ; Blindness

المؤلفون: Vendra V; Ophthalmic Molecular Genetics Section, Ophthalmic Genetics and Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, MD., Thangapandian M; Department of Biotechnology, K.S.Rangasamy College of Technology, Tamil Nadu, India.

المصدر: Molecular vision [Mol Vis] 2024 Feb 16; Vol. 30, pp. 37-48. Date of Electronic Publication: 2024 Feb 16 (Print Publication: 2024).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Molecular Vision Country of Publication: United States NLM ID: 9605351 Publication Model: eCollection Cited Medium: Internet ISSN: 1090-0535 (Electronic) Linking ISSN: 10900535 NLM ISO Abbreviation: Mol Vis Subsets: MEDLINE

مواضيع طبية MeSH: gamma-Crystallins*/chemistry , Lens, Crystalline*/metabolism , Cataract*/genetics , Cataract*/metabolism, Infant, Newborn ; Child ; Humans ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Mutation ; Mutagenesis, Site-Directed

المؤلفون: Zhu S; Eye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Provincial Key Laboratory of Ophthalmology, Zhejiang Provincial Clinical Research Center for Eye Diseases, Zhejiang Provincial Engineering Institute on Eye Diseases, Hangzhou 310009, Zhejiang, China., Xi Y; State Key Laboratory of Membrane Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China., Xu J; Eye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Provincial Key Laboratory of Ophthalmology, Zhejiang Provincial Clinical Research Center for Eye Diseases, Zhejiang Provincial Engineering Institute on Eye Diseases, Hangzhou 310009, Zhejiang, China., Hu L; State Key Laboratory of Membrane Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China; The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310052, China., Luo C; Eye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Provincial Key Laboratory of Ophthalmology, Zhejiang Provincial Clinical Research Center for Eye Diseases, Zhejiang Provincial Engineering Institute on Eye Diseases, Hangzhou 310009, Zhejiang, China., Yao K; Eye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Provincial Key Laboratory of Ophthalmology, Zhejiang Provincial Clinical Research Center for Eye Diseases, Zhejiang Provincial Engineering Institute on Eye Diseases, Hangzhou 310009, Zhejiang, China. Electronic address: xlren@zju.edu.cn., Chen X; Eye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Provincial Key Laboratory of Ophthalmology, Zhejiang Provincial Clinical Research Center for Eye Diseases, Zhejiang Provincial Engineering Institute on Eye Diseases, Hangzhou 310009, Zhejiang, China; Institute of Translational Medicine, Zhejiang University School of Medicine, 268 Kaixuan Road, Hangzhou 310020, China. Electronic address: chenxiangjun@zju.edu.cn.

المصدر: International journal of biological macromolecules [Int J Biol Macromol] 2023 Nov 01; Vol. 251, pp. 126339. Date of Electronic Publication: 2023 Aug 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

مواضيع طبية MeSH: Cataract*/genetics , Cataract*/congenital , Cataract*/metabolism , gamma-Crystallins*/genetics , gamma-Crystallins*/chemistry , gamma-Crystallins*/metabolism , Glycine*/chemistry , Glycine*/genetics , Molecular Dynamics Simulation* , Protein Stability*, Humans ; Mutation ; Protein Aggregates ; Hydrogen Bonding

المؤلفون: Lin N; Department of Nephrology, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang Province, China; Eye Center of the Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou 310009, China; Institute of Translational Medicine, Zhejiang University School of Medicine, 268 Kaixuan Road, Hangzhou 310020, China., Zhang Y; Eye Center of the Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou 310009, China; Institute of Translational Medicine, Zhejiang University School of Medicine, 268 Kaixuan Road, Hangzhou 310020, China., Song X; Eye Center of the Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou 310009, China., Xu J; Eye Center of the Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou 310009, China., Luo C; Eye Center of the Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou 310009, China., Tian Q; Eye Center of the Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou 310009, China; Institute of Translational Medicine, Zhejiang University School of Medicine, 268 Kaixuan Road, Hangzhou 310020, China., Yao K; Eye Center of the Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou 310009, China., Wu W; Eye Center of the Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou 310009, China. Electronic address: wwzju@zju.edu.cn., Chen X; Eye Center of the Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou 310009, China; Institute of Translational Medicine, Zhejiang University School of Medicine, 268 Kaixuan Road, Hangzhou 310020, China. Electronic address: chenxiangjun@zju.edu.cn., Hu L; Department of Nephrology, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang Province, China. Electronic address: hulidan@zju.edu.cn.

المصدر: International journal of biological macromolecules [Int J Biol Macromol] 2023 Dec 31; Vol. 253 (Pt 4), pp. 126910. Date of Electronic Publication: 2023 Sep 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

مواضيع طبية MeSH: Cataract*/metabolism , Lens, Crystalline*/metabolism , gamma-Crystallins*/chemistry, Humans ; Mutation ; Protein Conformation ; Protein Stability