المؤلفون: Kim M; Tri-Institutional PhD Program in Computational Biology & Medicine, Weill Cornell Medicine, New York City, NY, USA.; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Gorelick AN; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Vàzquez-García I; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Williams MJ; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Salehi S; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Shi H; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Weiner AC; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Ceglia N; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Funnell T; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Park T; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Boscenco S; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., O'Flanagan CH; Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada., Jiang H; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Grewal D; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Tang C; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Rusk N; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Gammage PA; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.; CRUK Beatson Institute, Glasgow, UK., McPherson A; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Aparicio S; Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada., Shah SP; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York City, NY, USA. shahs3@mskcc.org., Reznik E; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York City, NY, USA. reznike@mskcc.org.

المصدر: Nature genetics [Nat Genet] 2024 May; Vol. 56 (5), pp. 889-899. Date of Electronic Publication: 2024 May 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE

مواضيع طبية MeSH: DNA, Mitochondrial*/genetics , Single-Cell Analysis*/methods , Genome, Mitochondrial* , DNA Copy Number Variations*/genetics , Cell Nucleus*/genetics , Neoplasms*/genetics , Neoplasms*/pathology, Humans ; Cell Line, Tumor ; Animals ; Mitochondria/genetics ; Whole Genome Sequencing/methods ; Mice ; Heteroplasmy/genetics

المؤلفون: Mahmood M; Cancer Research UK Scotland Institute, Glasgow, UK., Liu EM; Computational Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Shergold AL; Cancer Research UK Scotland Institute, Glasgow, UK., Tolla E; Cancer Research UK Scotland Institute, Glasgow, UK., Tait-Mulder J; Cancer Research UK Scotland Institute, Glasgow, UK., Huerta-Uribe A; Cancer Research UK Scotland Institute, Glasgow, UK., Shokry E; Cancer Research UK Scotland Institute, Glasgow, UK., Young AL; Cancer Research UK Scotland Institute, Glasgow, UK., Lilla S; Cancer Research UK Scotland Institute, Glasgow, UK., Kim M; Computational Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Park T; Computational Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Boscenco S; Computational Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Manchon JL; Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain., Rodríguez-Antona C; Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Raras CIBERER, Madrid, Spain., Walters RC; Structural Biology Laboratory and York Biomedical Research Institute, Department of Chemistry, The University of York, York, UK., Springett RJ; Structural Biology Laboratory and York Biomedical Research Institute, Department of Chemistry, The University of York, York, UK., Blaza JN; Structural Biology Laboratory and York Biomedical Research Institute, Department of Chemistry, The University of York, York, UK., Mitchell L; Cancer Research UK Scotland Institute, Glasgow, UK., Blyth K; Cancer Research UK Scotland Institute, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK., Zanivan S; Cancer Research UK Scotland Institute, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK., Sumpton D; Cancer Research UK Scotland Institute, Glasgow, UK., Roberts EW; Cancer Research UK Scotland Institute, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK., Reznik E; Computational Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA. reznike@mskcc.org.; Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA. reznike@mskcc.org.; Urology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA. reznike@mskcc.org., Gammage PA; Cancer Research UK Scotland Institute, Glasgow, UK. payam.gammage@glasgow.ac.uk.; School of Cancer Sciences, University of Glasgow, Glasgow, UK. payam.gammage@glasgow.ac.uk.

المصدر: Nature cancer [Nat Cancer] 2024 Apr; Vol. 5 (4), pp. 659-672. Date of Electronic Publication: 2024 Jan 29.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-1347 (Electronic) Linking ISSN: 26621347 NLM ISO Abbreviation: Nat Cancer Subsets: MEDLINE

مواضيع طبية MeSH: DNA, Mitochondrial*/genetics , Melanoma*/genetics , Melanoma*/drug therapy , Mutation* , Immune Checkpoint Inhibitors*/therapeutic use , Immune Checkpoint Inhibitors*/pharmacology , Glycolysis*/genetics, Animals ; Mice ; Humans ; Tumor Microenvironment ; Cell Line, Tumor ; Electron Transport Complex I/genetics ; Electron Transport Complex I/metabolism ; Neutrophils/metabolism ; Neutrophils/immunology ; Mitochondria/metabolism ; Mitochondria/genetics ; Oxidative Phosphorylation/drug effects

المؤلفون: Mahmood M; Cancer Research UK Beatson Institute, Glasgow, UK., Liu EM; Computational Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Shergold AL; Cancer Research UK Beatson Institute, Glasgow, UK., Tolla E; Cancer Research UK Beatson Institute, Glasgow, UK., Tait-Mulder J; Cancer Research UK Beatson Institute, Glasgow, UK., Huerta Uribe A; Cancer Research UK Beatson Institute, Glasgow, UK., Shokry E; Cancer Research UK Beatson Institute, Glasgow, UK., Young AL; Cancer Research UK Beatson Institute, Glasgow, UK., Lilla S; Cancer Research UK Beatson Institute, Glasgow, UK., Kim M; Computational Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Park T; Computational Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Manchon JL; Centro Nacional de Investigaciones Oncológicas(CNIO), Madrid, Spain., Rodríguez-Antona C; Centro Nacional de Investigaciones Oncológicas(CNIO), Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Raras CIBERER, Madrid, Spain., Walters RC; Structural Biology Laboratory and York Biomedical Research Institute, Department of Chemistry, The University of York, York, UK., Springett RJ; Structural Biology Laboratory and York Biomedical Research Institute, Department of Chemistry, The University of York, York, UK., Blaza JN; Structural Biology Laboratory and York Biomedical Research Institute, Department of Chemistry, The University of York, York, UK., Zanivan S; Cancer Research UK Beatson Institute, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, UK., Sumpton D; Cancer Research UK Beatson Institute, Glasgow, UK., Roberts EW; Cancer Research UK Beatson Institute, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, UK., Reznik E; Computational Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Urology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Gammage PA; Cancer Research UK Beatson Institute, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, UK.

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2023 Mar 23. Date of Electronic Publication: 2023 Mar 23.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Shaw AM; CRUK Beatson Institute, Glasgow, UK., Gammage PA; CRUK Beatson Institute, Glasgow, UK. payam.gammage@glasgow.ac.uk.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK. payam.gammage@glasgow.ac.uk.

المصدر: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2023; Vol. 2615, pp. 31-40.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE

مواضيع طبية MeSH: DNA, Mitochondrial*/genetics , Mitochondria*/genetics, Animals ; Centrifugation ; Chromatography, Gel ; Polymerase Chain Reaction ; Mammals/genetics

المؤلفون: Kim M; Computational Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Mahmood M; CRUK Beatson Institute, Glasgow, UK., Reznik E; Computational Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Urology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: reznike@mskcc.org., Gammage PA; CRUK Beatson Institute, Glasgow, UK; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK. Electronic address: p.gammage@beatson.gla.ac.uk.

المصدر: Trends in cancer [Trends Cancer] 2022 Dec; Vol. 8 (12), pp. 1046-1059. Date of Electronic Publication: 2022 Aug 27.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101665956 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2405-8025 (Electronic) Linking ISSN: 24058025 NLM ISO Abbreviation: Trends Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Neoplasms*/genetics , Neoplasms*/metabolism , Genome, Mitochondrial*, Humans ; DNA, Mitochondrial/genetics ; Mitochondria/genetics ; Mitochondria/metabolism ; Mutation

المؤلفون: Ganly I; Human Oncology and Pathology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Liu EM; Computational Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Kuo F; Human Oncology and Pathology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Makarov V; Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA., Dong Y; Human Oncology and Pathology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Park J; Human Oncology and Pathology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Gong Y; Human Oncology and Pathology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Gorelick AN; Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Knauf JA; Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA., Benedetti E; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA., Tait-Mulder J; CRUK Beatson Institute, Glasgow, UK., Morris LGT; Human Oncology and Pathology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Fagin JA; Human Oncology and Pathology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Intlekofer AM; Human Oncology and Pathology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Krumsiek J; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA., Gammage PA; CRUK Beatson Institute, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Ghossein R; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Xu B; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Chan TA; Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA., Reznik E; Computational Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

المصدر: Science advances [Sci Adv] 2022 Jun 24; Vol. 8 (25), pp. eabn9699. Date of Electronic Publication: 2022 Jun 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Hepatocellular*/genetics , Liver Neoplasms*/genetics , Thyroid Neoplasms*/genetics , Thyroid Neoplasms*/pathology, DNA, Mitochondrial/genetics ; Genotype ; Humans ; Mutation ; Oxyphil Cells/pathology ; Tumor Microenvironment/genetics

المؤلفون: Gorelick AN; Computational Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Kim M; Computational Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Chatila WK; Computational Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., La K; Laboratory of Metabolic Regulation and Genetics, Rockefeller University, New York, NY, USA., Hakimi AA; Urology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Berger MF; Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Taylor BS; Computational Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Gammage PA; CRUK Beatson Institute, Glasgow, UK. payam.gammage@glasgow.ac.uk.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK. payam.gammage@glasgow.ac.uk., Reznik E; Computational Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA. reznike@mskcc.org.; Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA. reznike@mskcc.org.; Urology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA. reznike@mskcc.org.

المصدر: Nature metabolism [Nat Metab] 2021 Apr; Vol. 3 (4), pp. 558-570. Date of Electronic Publication: 2021 Apr 08.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Springer Nature Country of Publication: Germany NLM ID: 101736592 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2522-5812 (Electronic) Linking ISSN: 25225812 NLM ISO Abbreviation: Nat Metab Subsets: MEDLINE

مواضيع طبية MeSH: Oxidative Phosphorylation*, Cell Lineage/*genetics , DNA, Mitochondrial/*genetics , DNA, Neoplasm/*genetics, Adenosine Triphosphate/biosynthesis ; Colorectal Neoplasms/genetics ; Exome/genetics ; Genome, Human/genetics ; Genome, Mitochondrial ; Genotype ; Humans ; Membrane Potential, Mitochondrial/physiology ; Mitochondria/genetics ; Mutation/genetics ; Phenotype ; RNA/genetics

المؤلفون: Jackson CB; Stem Cells and Metabolism, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland., Turnbull DM; Wellcome Centre for Mitochondrial Research, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK., Minczuk M; MRC Mitochondrial Biology Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK., Gammage PA; CRUK Beatson Institute, Glasgow, UK; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK. Electronic address: payam.gammage@glasgow.ac.uk.

المصدر: Trends in molecular medicine [Trends Mol Med] 2020 Jul; Vol. 26 (7), pp. 698-709. Date of Electronic Publication: 2020 Mar 26.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 100966035 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-499X (Electronic) Linking ISSN: 14714914 NLM ISO Abbreviation: Trends Mol Med Subsets: MEDLINE

مواضيع طبية MeSH: DNA, Mitochondrial/*genetics , Heteroplasmy/*genetics , Mitochondria/*genetics, Animals ; Humans ; Mitochondrial Diseases/genetics ; Mutation/genetics

المؤلفون: Bacman SR; Department of Neurology, University of Miami School of Medicine, Miami, FL, United States., Gammage PA; CRUK Beatson Institute for Cancer Research, Glasgow, United Kingdom., Minczuk M; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, United Kingdom. Electronic address: michal.minczuk@mrc-mbu.cam.ac.uk., Moraes CT; Department of Neurology, University of Miami School of Medicine, Miami, FL, United States. Electronic address: cmoraes@med.miami.edu.

المصدر: Methods in cell biology [Methods Cell Biol] 2020; Vol. 155, pp. 441-487. Date of Electronic Publication: 2020 Jan 20.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 0373334 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0091-679X (Print) Linking ISSN: 0091679X NLM ISO Abbreviation: Methods Cell Biol Subsets: MEDLINE

مواضيع طبية MeSH: Genes, Mitochondrial*, DNA, Mitochondrial/*genetics , Heteroplasmy/*genetics, Animals ; COS Cells ; Chlorocebus aethiops ; Female ; HeLa Cells ; Humans ; Mice ; Mutation/genetics ; Plasmids/genetics ; Transcription Activator-Like Effector Nucleases ; Zinc Finger Nucleases/metabolism

المؤلفون: Andreazza S; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, UK., Samstag CL; Department of Genome Sciences, University of Washington, Seattle, WA, 98195, USA., Sanchez-Martinez A; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, UK., Fernandez-Vizarra E; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, UK., Gomez-Duran A; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, UK., Lee JJ; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, UK., Tufi R; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, UK., Hipp MJ; Department of Pathology, University of Washington, Seattle, WA, 98195, USA., Schmidt EK; Department of Pathology, University of Washington, Seattle, WA, 98195, USA., Nicholls TJ; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, UK., Gammage PA; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, UK., Chinnery PF; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, UK.; Department of Clinical Neuroscience, School of Clinical Medicine, University of Cambridge, Cambridge, CB2 0QQ, UK., Minczuk M; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, UK., Pallanck LJ; Department of Genome Sciences, University of Washington, Seattle, WA, 98195, USA., Kennedy SR; Department of Pathology, University of Washington, Seattle, WA, 98195, USA., Whitworth AJ; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, UK. a.whitworth@mrc-mbu.cam.ac.uk.

المصدر: Nature communications [Nat Commun] 2019 Jul 23; Vol. 10 (1), pp. 3280. Date of Electronic Publication: 2019 Jul 23.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: APOBEC-1 Deaminase/*physiology , DNA, Mitochondrial/*chemistry , Drosophila/*genetics, APOBEC-1 Deaminase/genetics ; APOBEC-1 Deaminase/metabolism ; Animals ; Drosophila/physiology ; Mitochondria/metabolism ; Mitochondria/physiology ; Models, Genetic ; Mutation ; Organisms, Genetically Modified