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المؤلفون: Westover JB; Institute for Antiviral Research, Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT, USA., Naik S; Arisan Therapeutics, San Diego, CA, USA., Bailey KW; Institute for Antiviral Research, Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT, USA., Wandersee L; Institute for Antiviral Research, Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT, USA., Gantla VR; Arisan Therapeutics, San Diego, CA, USA., Hickerson BT; Institute for Antiviral Research, Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT, USA., McCormack K; Arisan Therapeutics, San Diego, CA, USA. Electronic address: kenm@arisanthera.com., Henkel G; Arisan Therapeutics, San Diego, CA, USA. Electronic address: gregh@arisanthera.com., Gowen BB; Institute for Antiviral Research, Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT, USA. Electronic address: brian.gowen@usu.edu.

المصدر: Antiviral research [Antiviral Res] 2022 Dec; Vol. 208, pp. 105444. Date of Electronic Publication: 2022 Oct 13.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8109699 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9096 (Electronic) Linking ISSN: 01663542 NLM ISO Abbreviation: Antiviral Res Subsets: MEDLINE

مواضيع طبية MeSH: Hemorrhagic Fever, American*/drug therapy , Junin virus* , Hemorrhagic Fevers, Viral* , Arenaviridae*, Guinea Pigs ; Mice ; Animals ; Pyrazines/pharmacology ; Pyrazines/therapeutic use ; Amides/pharmacology ; Amides/therapeutic use ; Anti-Retroviral Agents/pharmacology

المؤلفون: Gowen BB; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT, USA. Electronic address: brian.gowen@usu.edu., Naik S; Arisan Therapeutics, San Diego, CA, USA., Westover JB; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT, USA., Brown ER; Arisan Therapeutics, San Diego, CA, USA., Gantla VR; Arisan Therapeutics, San Diego, CA, USA., Fetsko A; Arisan Therapeutics, San Diego, CA, USA., Dagley AL; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT, USA., Blotter DJ; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT, USA., Anderson N; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT, USA., McCormack K; Arisan Therapeutics, San Diego, CA, USA. Electronic address: kenm@arisanthera.com., Henkel G; Arisan Therapeutics, San Diego, CA, USA. Electronic address: gregh@arisanthera.com.

المصدر: Antiviral research [Antiviral Res] 2021 Sep; Vol. 193, pp. 105125. Date of Electronic Publication: 2021 Jun 29.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8109699 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9096 (Electronic) Linking ISSN: 01663542 NLM ISO Abbreviation: Antiviral Res Subsets: MEDLINE

مواضيع طبية MeSH: Antiviral Agents/*pharmacology , Arenaviridae Infections/*drug therapy , Arenaviruses, New World/*drug effects , Membrane Fusion/*drug effects , Small Molecule Libraries/*pharmacology, Administration, Oral ; Animals ; Antiviral Agents/pharmacokinetics ; Chlorocebus aethiops ; Male ; Mice ; Ribavirin/pharmacology ; Small Molecule Libraries/pharmacokinetics ; Vero Cells ; Viral Envelope Proteins/chemistry ; Viral Envelope Proteins/metabolism ; Virus Internalization/drug effects

المؤلفون: Plewe MB; Arisan Therapeutics, 11189 Sorrento Valley Rd, Suite 104, San Diego 92121, CA, United States., Gantla VR; Arisan Therapeutics, 11189 Sorrento Valley Rd, Suite 104, San Diego 92121, CA, United States., Sokolova NV; Arisan Therapeutics, 11189 Sorrento Valley Rd, Suite 104, San Diego 92121, CA, United States., Shin YJ; Arisan Therapeutics, 11189 Sorrento Valley Rd, Suite 104, San Diego 92121, CA, United States., Naik S; Arisan Therapeutics, 11189 Sorrento Valley Rd, Suite 104, San Diego 92121, CA, United States., Brown ER; Arisan Therapeutics, 11189 Sorrento Valley Rd, Suite 104, San Diego 92121, CA, United States., Fetsko A; Arisan Therapeutics, 11189 Sorrento Valley Rd, Suite 104, San Diego 92121, CA, United States., Zhang L; Department of Pathology, and Center for Biodefense and Emerging Infectious Diseases, The University of Texas Medical Branch, Galveston 77555, TX, United States., Kalveram B; Department of Pathology, and Center for Biodefense and Emerging Infectious Diseases, The University of Texas Medical Branch, Galveston 77555, TX, United States., Freiberg AN; Department of Pathology, and Center for Biodefense and Emerging Infectious Diseases, The University of Texas Medical Branch, Galveston 77555, TX, United States., Henkel G; Arisan Therapeutics, 11189 Sorrento Valley Rd, Suite 104, San Diego 92121, CA, United States., McCormack K; Arisan Therapeutics, 11189 Sorrento Valley Rd, Suite 104, San Diego 92121, CA, United States. Electronic address: kenm@arisanthera.com.

المصدر: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2021 Jun 01; Vol. 41, pp. 127983. Date of Electronic Publication: 2021 May 05.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

مواضيع طبية MeSH: Drug Discovery*, Antiviral Agents/*pharmacology , Arenavirus/*drug effects , Heterocyclic Compounds/*pharmacology , Viral Envelope Proteins/*antagonists & inhibitors, Antiviral Agents/chemical synthesis ; Antiviral Agents/chemistry ; Arenavirus/metabolism ; Dose-Response Relationship, Drug ; Heterocyclic Compounds/chemical synthesis ; Heterocyclic Compounds/chemistry ; Humans ; Microbial Sensitivity Tests ; Molecular Structure ; Structure-Activity Relationship ; Viral Envelope Proteins/metabolism

المؤلفون: Plewe MB; Arisan Therapeutics, 11189 Sorrento Valley Road, Suite 104, San Diego, California 92121, United States., Sokolova NV; Arisan Therapeutics, 11189 Sorrento Valley Road, Suite 104, San Diego, California 92121, United States., Gantla VR; Arisan Therapeutics, 11189 Sorrento Valley Road, Suite 104, San Diego, California 92121, United States., Brown ER; Arisan Therapeutics, 11189 Sorrento Valley Road, Suite 104, San Diego, California 92121, United States., Naik S; Arisan Therapeutics, 11189 Sorrento Valley Road, Suite 104, San Diego, California 92121, United States., Fetsko A; Arisan Therapeutics, 11189 Sorrento Valley Road, Suite 104, San Diego, California 92121, United States., Lorimer DD; Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle, Washington 98105, United States.; UCB Pharma, 7869 NE Day Road West, Bainbridge Island, Washington 98110, United States., Dranow DM; Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle, Washington 98105, United States.; UCB Pharma, 7869 NE Day Road West, Bainbridge Island, Washington 98110, United States., Smutney H; Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle, Washington 98105, United States.; UCB Pharma, 3 Preston Court, Bedford, Massachusetts 01730, United States., Bullen J; Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle, Washington 98105, United States.; UCB Pharma, 7869 NE Day Road West, Bainbridge Island, Washington 98110, United States., Sidhu R; Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle, Washington 98105, United States.; UCB Pharma, 3 Preston Court, Bedford, Massachusetts 01730, United States., Master A; Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle, Washington 98105, United States.; UCB Pharma, 3 Preston Court, Bedford, Massachusetts 01730, United States., Wang J; Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle, Washington 98105, United States.; UCB Pharma, 3 Preston Court, Bedford, Massachusetts 01730, United States., Kallel EA; Victrix, 12631 Bendito Drive, San Diego, California 92128, United States., Zhang L; Department of Pathology andCenter for Biodefense and Emerging Infectious Diseases, The University of Texas Medical Branch, Galveston, Texas 77555, United States., Kalveram B; Department of Pathology andCenter for Biodefense and Emerging Infectious Diseases, The University of Texas Medical Branch, Galveston, Texas 77555, United States., Freiberg AN; Department of Pathology andCenter for Biodefense and Emerging Infectious Diseases, The University of Texas Medical Branch, Galveston, Texas 77555, United States.; Department of Pathology andCenter for Biodefense and Emerging Infectious Diseases, The University of Texas Medical Branch, Galveston, Texas 77555, United States., Henkel G; Arisan Therapeutics, 11189 Sorrento Valley Road, Suite 104, San Diego, California 92121, United States., McCormack K; Arisan Therapeutics, 11189 Sorrento Valley Road, Suite 104, San Diego, California 92121, United States.

المصدر: ACS medicinal chemistry letters [ACS Med Chem Lett] 2020 May 01; Vol. 11 (6), pp. 1160-1167. Date of Electronic Publication: 2020 May 01 (Print Publication: 2020).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE

المؤلفون: Plewe MB; Arisan Therapeutics, 11189 Sorrento Valley Rd, Suite 104, San Diego, CA 92054, United States., Whitby LR; Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, United States., Naik S; Arisan Therapeutics, 11189 Sorrento Valley Rd, Suite 104, San Diego, CA 92054, United States., Brown ER; Arisan Therapeutics, 11189 Sorrento Valley Rd, Suite 104, San Diego, CA 92054, United States., Sokolova NV; Arisan Therapeutics, 11189 Sorrento Valley Rd, Suite 104, San Diego, CA 92054, United States., Gantla VR; Arisan Therapeutics, 11189 Sorrento Valley Rd, Suite 104, San Diego, CA 92054, United States., York J; Montana Biotechnology Center, The University of Montana, Missoula, MT 59812, United States., Nunberg JH; Montana Biotechnology Center, The University of Montana, Missoula, MT 59812, United States., Zhang L; Department of Pathology, The University of Texas Medical Branch, Galveston, TX 77555, United States., Kalveram B; Department of Pathology, The University of Texas Medical Branch, Galveston, TX 77555, United States., Freiberg AN; Department of Pathology, The University of Texas Medical Branch, Galveston, TX 77555, United States; Center for Biodefense and Emerging Infectious Diseases, The University of Texas Medical Branch, Galveston, TX 77555, United States., Boger DL; Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, United States; The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, United States., Henkel G; Arisan Therapeutics, 11189 Sorrento Valley Rd, Suite 104, San Diego, CA 92054, United States., McCormack K; Arisan Therapeutics, 11189 Sorrento Valley Rd, Suite 104, San Diego, CA 92054, United States. Electronic address: kenm@arisanthera.com.

المصدر: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2019 Nov 15; Vol. 29 (22), pp. 126620. Date of Electronic Publication: 2019 Aug 24.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

مواضيع طبية MeSH: Antiviral Agents/*pharmacology , Arenavirus/*drug effects , Piperazines/*pharmacology , Viral Envelope Proteins/*antagonists & inhibitors, Antiviral Agents/chemical synthesis ; Antiviral Agents/chemistry ; Arenavirus/metabolism ; Dose-Response Relationship, Drug ; Microbial Sensitivity Tests ; Molecular Structure ; Piperazines/chemical synthesis ; Piperazines/chemistry ; Structure-Activity Relationship ; Viral Envelope Proteins/metabolism