-
1كتاب إلكتروني
المؤلفون: Barbachyn, Michael R., Brickner, Steven J., Gadwood, Robert C., Garmon, Stuart A., Grega, Kevin C., Hutchinson, Douglas K., Munesada, Kiyotaka, Reischer, Robert J., Taniguchi, Mikio, Thomasco, Lisa M., Toops, Dana S., Yamada, Hiromi, Ford, Charles W., Zurenko, Gary E.
المساهمون: Rosen, Barry P., editorAff1, Mobashery, Shahriar, editorAff1
المصدر: Resolving the Antibiotic Paradox : Progress in Understanding Drug Resistance and Development of New Antibiotics. 456:219-238
-
2دورية أكاديمية
المصدر: Separation Science & Technology; Jan1993, Vol. 28 Issue 1-3, p1-23, 23p
-
3دورية أكاديمية
المؤلفون: Barbachyn MR; Combinatorial and Medicinal Chemistry, Pharmacia Corporation, 7000 Portage Road, Kalamazoo, Michigan 49001, USA. michael.r.barbachyn@pharmacia.com, Cleek GJ, Dolak LA, Garmon SA, Morris J, Seest EP, Thomas RC, Toops DS, Watt W, Wishka DG, Ford CW, Zurenko GE, Hamel JC, Schaadt RD, Stapert D, Yagi BH, Adams WJ, Friis JM, Slatter JG, Sams JP, Oien NL, Zaya MJ, Wienkers LC, Wynalda MA
المصدر: Journal of medicinal chemistry [J Med Chem] 2003 Jan 16; Vol. 46 (2), pp. 284-302.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print Cited Medium: Print ISSN: 0022-2623 (Print) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
مواضيع طبية MeSH: Anti-Bacterial Agents/*chemical synthesis , Benzene Derivatives/*chemical synthesis , Gram-Positive Bacteria/*drug effects , Isoxazoles/*chemical synthesis , Piperazines/*chemical synthesis, Animals ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; Benzene Derivatives/chemistry ; Benzene Derivatives/pharmacology ; Biological Availability ; Crystallography, X-Ray ; Cytochrome P-450 Enzyme Inhibitors ; Cytochrome P-450 Enzyme System/chemistry ; Drug Resistance, Bacterial ; Hepatocytes/metabolism ; Humans ; In Vitro Techniques ; Isoxazoles/chemistry ; Isoxazoles/pharmacology ; Male ; Mice ; Microbial Sensitivity Tests ; Piperazines/chemistry ; Piperazines/pharmacology ; Rats ; Rats, Sprague-Dawley ; Staphylococcal Infections/mortality ; Staphylococcus aureus ; Stereoisomerism ; Structure-Activity Relationship