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1دورية أكاديمية
المؤلفون: Helge M. Magnussen, Syed F. Ahmed, Gary. J. Sibbet, Ventzislava A. Hristova, Koji Nomura, Andreas K. Hock, Lewis J. Archibald, Andrew G. Jamieson, David Fushman, Karen H. Vousden, Allan M. Weissman, Danny T. Huang
المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2041-1723
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المؤلفون: Mark A. Nakasone, Karolina A. Majorek, Mads Gabrielsen, Gary J. Sibbet, Brian O. Smith, Danny T. Huang
المصدر: Nature Chemical Biology. 18:422-431
مصطلحات موضوعية: Cell Biology, Molecular Biology
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3E3 ligase-inactivation rewires CBL interactome to elicit oncogenesis by hijacking RTK–CBL–CIN85 axis
المؤلفون: Danny T. Huang, David Sumpton, Sergio Lilla, Lori Buetow, Syed Feroj Ahmed, William C. Clark, Gary J. Sibbet, Ann Hedley, Sara Zanivan, Mads Gabrielsen
المصدر: Oncogene
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Lymphoma, B-Cell, Ubiquitylation, Endosome, Receptor Protein-Tyrosine Kinases, Mutant, Breast Neoplasms, macromolecular substances, Biology, medicine.disease_cause, environment and public health, Interactome, Article, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, hemic and lymphatic diseases, Genetics, medicine, Humans, Proto-Oncogene Proteins c-cbl, Molecular Biology, Adaptor Proteins, Signal Transducing, Cell Proliferation, Myeloproliferative Disorders, Ubiquitin, fungi, Cancer, Oncogenes, medicine.disease, Ubiquitin ligase, ErbB Receptors, Gene Expression Regulation, Neoplastic, enzymes and coenzymes (carbohydrates), 030104 developmental biology, Tissue Array Analysis, 030220 oncology & carcinogenesis, Mutation, Proteolysis, biology.protein, Cancer research, Female, Carcinogenesis, Protein Binding
وصف الملف: application/pdf
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المؤلفون: Mark A, Nakasone, Karolina A, Majorek, Mads, Gabrielsen, Gary J, Sibbet, Brian O, Smith, Danny T, Huang
المصدر: Nature chemical biology. 18(4)
مصطلحات موضوعية: Protein Domains, Ubiquitin, Ubiquitin-Conjugating Enzymes, Ubiquitination, Polyubiquitin, Protein Binding
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المؤلفون: Sara Zanivan, Lori Buetow, Chatrin Chatrin, Danny T. Huang, Sergio Lilla, Syed Feroj Ahmed, Gary J. Sibbet, Mads Gabrielsen
المصدر: Science Advances
مصطلحات موضوعية: Poly Adenosine Diphosphate Ribose, Ubiquitin-Protein Ligases, Interactome, Biochemistry, Domain (software engineering), 03 medical and health sciences, 0302 clinical medicine, PARP1, Ubiquitin, Structural Biology, Humans, Ring domain, Research Articles, 030304 developmental biology, 0303 health sciences, Multidisciplinary, biology, Chemistry, C-terminus, Ubiquitination, SciAdv r-articles, 3. Good health, Cell biology, Adenosine Diphosphate, biology.protein, Signal transduction, 030217 neurology & neurosurgery, Function (biology), Research Article
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af33917f9c6abc0821c6c526665cea28
https://eprints.gla.ac.uk/222684/1/222684.pdf -
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المؤلفون: Brian O. Smith, Gary J. Sibbet, Chatrin Chatrin, David Sumpton, Mads Gabrielsen, Syed Feroj Ahmed, Danny T. Huang, Mark A. Nakasone, Lori Buetow
المصدر: Science Advances
مصطلحات موضوعية: Future studies, Ubiquitin-Protein Ligases, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, ADP-Ribosylation, Ubiquitin, Structural Biology, Humans, Ring domain, Research Articles, 030304 developmental biology, 0303 health sciences, Multidisciplinary, biology, Chemistry, Ubiquitination, SciAdv r-articles, NAD, 3. Good health, Cell biology, ADP-ribosylation, biology.protein, NAD+ kinase, 030217 neurology & neurosurgery, Function (biology), Research Article
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3f05735803f347e349100b8c131a59d
https://pubmed.ncbi.nlm.nih.gov/32948590 -
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المؤلفون: Syed Faisal Ahmed, Andrew G. Jamieson, Andreas K. Hock, Helge M. Magnussen, Karen H. Vousden, Ventzislava A. Hristova, Lewis J. Archibald, Danny T. Huang, Gary J. Sibbet, Koji Nomura, David Fushman, Allan M. Weissman
المصدر: Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, DNA damage, Science, General Physics and Astronomy, DNA damage response, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, chemistry.chemical_compound, Phosphoserine, Structure-Activity Relationship, 0302 clinical medicine, Ubiquitin, Cell Line, Tumor, Humans, Amino Acid Sequence, Phosphorylation, lcsh:Science, neoplasms, X-ray crystallography, chemistry.chemical_classification, DNA ligase, Multidisciplinary, biology, Proto-Oncogene Proteins c-mdm2, General Chemistry, Ubiquitin ligase, Cell biology, enzymes and coenzymes (carbohydrates), 030104 developmental biology, chemistry, Structural biology, Ubiquitin ligases, Proteolysis, biology.protein, Mdm2, lcsh:Q, Protein Multimerization, RING Finger Domains, 030217 neurology & neurosurgery, DNA, DNA Damage, Protein Binding
وصف الملف: application/pdf
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المؤلفون: Amrita Patel, Gary J. Sibbet, Danny T. Huang
المصدر: Journal of Biological Chemistry
The Journal of Biological Chemistryمصطلحات موضوعية: 0301 basic medicine, Models, Molecular, ubiquitin-conjugating enzyme (E2 enzyme), Stereochemistry, Protein Conformation, Protein degradation, Ring (chemistry), Crystallography, X-Ray, Biochemistry, ubiquitin ligase, Inhibitor of Apoptosis Proteins, Turn (biochemistry), 03 medical and health sciences, Ubiquitin, structural biology, Humans, ubiquitylation (ubiquitination), RING E3, Molecular Biology, UbcH5B, chemistry.chemical_classification, DNA ligase, 030102 biochemistry & molecular biology, biology, Chemistry, apoptosis, Ubiquitination, Cell Biology, non-covalent, allosteric regulation, Ubiquitin ligase, cIAP1, 030104 developmental biology, Structural biology, E3 ubiquitin ligase, Covalent bond, Protein Synthesis and Degradation, Ubiquitin-Conjugating Enzymes, biology.protein, protein degradation, activation, Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f0ed8fbc72a4ec2f42fb5cf9ce61444
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9Structural analysis of MDM2 RING separates degradation from regulation of p53 transcription activity
المؤلفون: Karen H. Vousden, Marta Klejnot, Gary J. Sibbet, Dominika Kowalczyk, Danny T. Huang, Andreas K. Hock, Koji Nomura
المصدر: Nature Structural & Molecular Biology
مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Transcription, Genetic, Protein Conformation, Cell Cycle Proteins, Crystallography, X-Ray, Article, 03 medical and health sciences, Structural Biology, Transcription (biology), Proto-Oncogene Proteins, Ring domain, Molecular Biology, neoplasms, chemistry.chemical_classification, Transcriptional activity, DNA ligase, biology, Nuclear Proteins, Proto-Oncogene Proteins c-mdm2, 3. Good health, Cell biology, 030104 developmental biology, chemistry, Proteolysis, Ubiquitin-Conjugating Enzymes, biology.protein, Mdm2, Mutant Proteins, Tumor Suppressor Protein p53, Protein Binding
وصف الملف: application/pdf
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المؤلفون: Dmitri I. Svergun, Lori Buetow, Hao Dou, Gary J. Sibbet, Syed Feroj Ahmed, Giancarlo Tria, Danny T. Huang, Andreas K. Hock
المساهمون: Institute of Nanoscopy (IoN), RS: M4I - Nanoscopy
المصدر: BMC Biology
Bmc Biology, 14:76. BioMed Central
BMC biology 14(1), 76 (2016). doi:10.1186/s12915-016-0298-6مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, Physiology, Mutant, Plant Science, environment and public health, Myeloproliferative neoplasms, Mice, 0302 clinical medicine, Ubiquitin, Structural Biology, Neoplasms, hemic and lymphatic diseases, Native state, Phosphorylation, chemistry.chemical_classification, Agricultural and Biological Sciences(all), biology, 3T3 Cells, SAXS, Oncogene Protein v-cbl, 3. Good health, Ubiquitin ligase, 030220 oncology & carcinogenesis, General Agricultural and Biological Sciences, Tyrosine kinase, hormones, hormone substitutes, and hormone antagonists, Research Article, Biotechnology, Cbl, Transformation potential, macromolecular substances, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, ddc:570, Animals, Point Mutation, Ecology, Evolution, Behavior and Systematics, Cell Proliferation, DNA ligase, Myeloproliferative Disorders, Biochemistry, Genetics and Molecular Biology(all), Point mutation, fungi, Cell Biology, Molecular biology, enzymes and coenzymes (carbohydrates), 030104 developmental biology, chemistry, biology.protein, Developmental Biology
وصف الملف: application/pdf
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