نتائج البحث - "Gary T. Pauly"

1

دورية أكاديمية

Creatine riboside is a cancer cell–derived metabolite associated with arginine auxotrophy

المصدر: The Journal of Clinical Investigation, Vol 132, Iss 14 (2022)

مصطلحات موضوعية: Oncology, Medicine

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1558-8238

URL الوصول: https://doaj.org/article/cade40de76004f3eac0d8228a46781a4

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2

دورية أكاديمية

Reactive astrocytic S1P3 signaling modulates the blood–tumor barrier in brain metastases

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/69cb9612d00a46d3a48171a71ecd0d7b

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3

دورية أكاديمية

Infectious Entry and Neutralization of Pathogenic JC Polyomaviruses

المؤلفون: Eileen M. Geoghegan, Diana V. Pastrana, Rachel M. Schowalter, Upasana Ray, Wei Gao, Mitchell Ho, Gary T. Pauly, Dina M. Sigano, Campbell Kaynor, Ellen Cahir-McFarland, Benoit Combaluzier, Jan Grimm, Christopher B. Buck

المصدر: Cell Reports, Vol 21, Iss 5, Pp 1169-1179 (2017)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124717314596; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/940b16d5a0d7411789fc82a19047a02f

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4

Structure–Activity Relationships of Pyrazolo[1,5-a]pyrimidin-7(4H)-ones as Antitubercular Agents

المؤلفون: Clifton E. Barry, Paul G. Wyatt, Yoshitaka Tateishi, Andaleeb Sajid, M. Daben J. Libardo, Sangmi Oh, Caroline J. Duncombe, Peter C. Ray, David W. Gray, Gary T. Pauly, Jose Santinni O Roma, Thomas R. Ioerger, Helena I. Boshoff, Shaik Azeeza, Michael Goodwin

المصدر: ACS Infectious Diseases. 7:479-492

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f2b286eaa3ebb59880cbd57cff884986
https://doi.org/10.1021/acsinfecdis.0c00851

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5

Structure‐based non‐nucleoside inhibitor design: Developing inhibitors that are effective against resistant mutants

المؤلفون: Gary T. Pauly, Katharine Hewlett, Stephen H. Hughes, Steven J. Smith, Joel P. Schneider

المصدر: Chemical Biology & Drug Design

مصطلحات موضوعية: Efavirenz, Anti-HIV Agents, Pyridones, Mutant, Binding pocket, HIV Infections, Molecular Dynamics Simulation, 01 natural sciences, Biochemistry, Nucleoside Reverse Transcriptase Inhibitor, chemistry.chemical_compound, immune system diseases, Doravirine, Drug Discovery, reverse transcriptase, Drug Resistance, Viral, Humans, Research Articles, Pharmacology, drug resistance, Binding Sites, 010405 organic chemistry, Organic Chemistry, Rilpivirine, virus diseases, binding pocket, HIV, Triazoles, Virology, Reverse transcriptase, HIV Reverse Transcriptase, 0104 chemical sciences, inhibitor, 010404 medicinal & biomolecular chemistry, Pyrimidines, chemistry, Drug Design, Mutation, HIV-1, Molecular Medicine, Resistant mutants, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26a10e1f1d6c399868af6cb7264ab59c
http://europepmc.org/articles/PMC7821153

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Creatine riboside is a cancer cell-derived metabolite associated with arginine auxotrophy

المصدر: The Journal of clinical investigation. 132(14)

مصطلحات موضوعية: Liver Neoplasms, Humans, General Medicine, Ribonucleosides, Arginine, Creatine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c59beebecda228d777274251164bf6ce
https://pubmed.ncbi.nlm.nih.gov/35838048

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7

Structure-Activity Relationships of Pyrazolo[1,5

المؤلفون: Sangmi, Oh, M Daben J, Libardo, Shaik, Azeeza, Gary T, Pauly, Jose Santinni O, Roma, Andaleeb, Sajid, Yoshitaka, Tateishi, Caroline, Duncombe, Michael, Goodwin, Thomas R, Ioerger, Paul G, Wyatt, Peter C, Ray, David W, Gray, Helena I M, Boshoff, Clifton E, Barry

المصدر: ACS Infectious Diseases

مصطلحات موضوعية: structure−activity relationship, Structure-Activity Relationship, tuberculosis, Antitubercular Agents, antitubercular activity, Mycobacterium tuberculosis, pyrazolo[1,5-a]pyrimidin-7(4H)-one, Article, High-Throughput Screening Assays

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::d2eb5f816040cc19e46ca7fcd8417fa0
https://pubmed.ncbi.nlm.nih.gov/33405882

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8

Reactive astrocytic S1P3 signaling modulates the blood–tumor barrier in brain metastases

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Science, General Physics and Astronomy, Mice, Nude, Triple Negative Breast Neoplasms, CCL2, Injections, Intramuscular, General Biochemistry, Genetics and Molecular Biology, Article, Permeability, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, In vivo, Cell Line, Tumor, Animals, Humans, Secretion, Receptor, lcsh:Science, Chemokine CCL2, Fluorescent Dyes, Multidisciplinary, Antibiotics, Antineoplastic, Chemistry, Brain Neoplasms, Interleukin-6, Myocardium, General Chemistry, Endothelial stem cell, Gene Expression Regulation, Neoplastic, Receptors, Lysosphingolipid, 030104 developmental biology, Xanthenes, Cell culture, Blood-Brain Barrier, Doxorubicin, 030220 oncology & carcinogenesis, Astrocytes, Cancer research, Female, lcsh:Q, Signal transduction, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63fc2c39e48d4f9f46a5df2529122578
http://link.springer.com/article/10.1038/s41467-018-05030-w

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9

Inhibiting Janus Kinase 1 and BCL-2 to treat T cell acute lymphoblastic leukemia with IL7-Rα mutations

المؤلفون: Caroline Andrews, Timothy C. Back, Sarah D. Cramer, Gary T. Pauly, Julie A. Hixon, Emilee Senkevitch, Kelli Czarra, Scott K. Durum, Wenqing Li

المصدر: Oncotarget

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4db7133020e9ce2db6de8bbe87180ab8
http://europepmc.org/articles/PMC5978251

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Blocking downstream signaling pathways in the context of HDAC inhibition promotes apoptosis preferentially in cells harboring mutant Ras

المؤلفون: Robert W. Robey, Arup R. Chakraborty, Joel P. Schneider, Agnes Basseville, Susan E. Bates, Gary T. Pauly, Julian C. Bahr, Hanna Kozlowski, Paresma Patel, Victoria Luchenko, Michael M. Gottesman

المصدر: Oncotarget

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, medicine.drug_class, Context (language use), Biology, Ras mutation, AKT inhibitor, Romidepsin, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Cell Line, Tumor, Depsipeptides, medicine, romidepsin, Humans, Extracellular Signal-Regulated MAP Kinases, PI3K/AKT/mTOR pathway, Phosphoinositide-3 Kinase Inhibitors, Mitogen-Activated Protein Kinase Kinases, MEK inhibitor, Kinase, Histone deacetylase inhibitor, apoptosis, Histone Deacetylase Inhibitors, 030104 developmental biology, Genes, ras, Oncology, chemistry, 030220 oncology & carcinogenesis, Immunology, Mutation, Cancer research, Belinostat, Proto-Oncogene Proteins c-akt, medicine.drug, Research Paper, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26ba77e65e9b74db7882543e538cf912
http://europepmc.org/articles/PMC5340114

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