المؤلفون: Xu D; Howard Hughes Medical Institute, New Haven, CT, USA.; Yale Systems Biology Institute, West Haven, CT, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, USA., Jiang W; Howard Hughes Medical Institute, New Haven, CT, USA.; Yale Systems Biology Institute, West Haven, CT, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA., Wu L; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA., Gaudet RG; Howard Hughes Medical Institute, New Haven, CT, USA.; Yale Systems Biology Institute, West Haven, CT, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, USA., Park ES; Howard Hughes Medical Institute, New Haven, CT, USA.; Yale Systems Biology Institute, West Haven, CT, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, USA., Su M; Department of Cell Biology, Yale University School of Medicine, New Haven, CT, USA., Cheppali SK; Yale Nanobiology Institute, West Haven, CT, USA.; Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT, USA., Cheemarla NR; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA., Kumar P; Howard Hughes Medical Institute, New Haven, CT, USA.; Yale Systems Biology Institute, West Haven, CT, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, USA., Uchil PD; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, USA., Grover JR; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, USA., Foxman EF; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA., Brown CM; School of Life Sciences and Department of Chemistry, University of Warwick, Coventry, UK., Stansfeld PJ; School of Life Sciences and Department of Chemistry, University of Warwick, Coventry, UK., Bewersdorf J; Department of Cell Biology, Yale University School of Medicine, New Haven, CT, USA., Mothes W; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, USA., Karatekin E; Yale Nanobiology Institute, West Haven, CT, USA.; Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.; Saints-Pères Paris Institute for the Neurosciences, Université de Paris, Centre National de la Recherche Scientifique UMR 8003, Paris, France.; Wu Tsai Institute, Yale University, New Haven, CT, USA., Wilen CB; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA., MacMicking JD; Howard Hughes Medical Institute, New Haven, CT, USA. john.macmicking@yale.edu.; Yale Systems Biology Institute, West Haven, CT, USA. john.macmicking@yale.edu.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA. john.macmicking@yale.edu.; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, USA. john.macmicking@yale.edu.

المصدر: Nature [Nature] 2023 Jul; Vol. 619 (7971), pp. 819-827. Date of Electronic Publication: 2023 Jul 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19*/immunology , COVID-19*/metabolism , COVID-19*/prevention & control , COVID-19*/virology , Phospholipid Transfer Proteins*/chemistry , Phospholipid Transfer Proteins*/genetics , Phospholipid Transfer Proteins*/immunology , Phospholipid Transfer Proteins*/metabolism , SARS-CoV-2*/classification , SARS-CoV-2*/immunology , SARS-CoV-2*/metabolism , SARS-CoV-2*/pathogenicity, Animals ; Humans ; Mice ; Antibodies, Neutralizing/immunology ; Antibodies, Viral/immunology ; Chiroptera ; Exome Sequencing ; Hepatocytes/immunology ; Hepatocytes/metabolism ; Interferon-gamma/immunology ; Lung/immunology ; Lung/metabolism ; Membrane Fusion ; Virus Internalization

SCR Organism: SARS-CoV-2 variants

المؤلفون: Gaudet RG; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510, USA.; Yale Systems Biology Institute, West Haven, CT 06477, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06510, USA., Zhu S; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510, USA.; Yale Systems Biology Institute, West Haven, CT 06477, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06510, USA., Halder A; Yale Nanobiology Institute, West Haven, CT 06477, USA.; Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06510, USA., Kim BH; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510, USA.; Yale Systems Biology Institute, West Haven, CT 06477, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06510, USA., Bradfield CJ; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510, USA.; Yale Systems Biology Institute, West Haven, CT 06477, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06510, USA., Huang S; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510, USA.; Yale Systems Biology Institute, West Haven, CT 06477, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06510, USA., Xu D; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510, USA.; Yale Systems Biology Institute, West Haven, CT 06477, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06510, USA., Mamiñska A; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510, USA.; Yale Systems Biology Institute, West Haven, CT 06477, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06510, USA., Nguyen TN; Department of Biochemistry and Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Melbourne 3800, Australia., Lazarou M; Department of Biochemistry and Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Melbourne 3800, Australia., Karatekin E; Yale Nanobiology Institute, West Haven, CT 06477, USA.; Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06510, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06510, USA.; Saints-Pères Paris Institute for the Neurosciences, Centre National de la Recherche Scientifique (CNRS), Université de Paris, F-75006 Paris, France., Gupta K; Yale Nanobiology Institute, West Haven, CT 06477, USA.; Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06510, USA., MacMicking JD; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510, USA. john.macmicking@yale.edu.; Yale Systems Biology Institute, West Haven, CT 06477, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06510, USA.

المصدر: Science (New York, N.Y.) [Science] 2021 Jul 16; Vol. 373 (6552).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Apolipoproteins L/*metabolism , Cell Membrane/*metabolism , Cytosol/*microbiology , Gram-Negative Bacteria/*physiology , Interferon-gamma/*immunology, Apolipoproteins L/chemistry ; Apolipoproteins L/genetics ; Bacterial Outer Membrane/metabolism ; Bacteriolysis ; CRISPR-Cas Systems ; Cell Membrane/chemistry ; Cell Membrane/ultrastructure ; Cell Membrane Permeability ; Cells, Cultured ; Detergents/metabolism ; GTP-Binding Proteins/metabolism ; Gene Editing ; Gram-Negative Bacteria/immunology ; Gram-Negative Bacteria/pathogenicity ; Gram-Negative Bacteria/ultrastructure ; Humans ; Immunity, Innate ; Lipoproteins/chemistry ; Microbial Viability ; O Antigens/metabolism ; Protein Domains ; Salmonella typhimurium/immunology ; Salmonella typhimurium/pathogenicity ; Salmonella typhimurium/physiology ; Salmonella typhimurium/ultrastructure ; Solubility

المؤلفون: Abdel-Nour M; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Carneiro LAM; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Downey J; Department of Microbiology and Immunology, McGill University, Montreal, QC, Canada., Tsalikis J; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Outlioua A; INSERM U1197, Hôpital Paul Brousse, Bâtiment Lavoisier, 94807 Villejuif Cedex, France.; Molecular Genetics and Immunophysiopathology Research Team, Health and Environment Laboratory, Aïn Chock Faculty of Sciences, Hassan II University of Casablanca, Casablanca, Morocco., Prescott D; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; Department of Immunology, University of Toronto, Toronto, ON, Canada., Da Costa LS; INSERM U1197, Hôpital Paul Brousse, Bâtiment Lavoisier, 94807 Villejuif Cedex, France., Hovingh ES; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Farahvash A; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Gaudet RG; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada., Molinaro R; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., van Dalen R; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Lau CCY; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; Department of Immunology, University of Toronto, Toronto, ON, Canada., Azimi FC; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Escalante NK; Department of Immunology, University of Toronto, Toronto, ON, Canada., Trotman-Grant A; Department of Immunology, University of Toronto, Toronto, ON, Canada., Lee JE; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Gray-Owen SD; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada., Divangahi M; Department of Microbiology and Immunology, McGill University, Montreal, QC, Canada., Chen JJ; Institute of Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA., Philpott DJ; Department of Immunology, University of Toronto, Toronto, ON, Canada., Arnoult D; INSERM U1197, Hôpital Paul Brousse, Bâtiment Lavoisier, 94807 Villejuif Cedex, France., Girardin SE; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada. stephen.girardin@utoronto.ca damien.arnoult@inserm.fr.

المصدر: Science (New York, N.Y.) [Science] 2019 Jul 05; Vol. 365 (6448).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Immunity, Innate*, Cytosol/*enzymology , Cytosol/*immunology , Protein Serine-Threonine Kinases/*physiology , Unfolded Protein Response/*immunology, Activating Transcription Factor 4/metabolism ; Adaptor Proteins, Signal Transducing/metabolism ; Adaptor Proteins, Vesicular Transport/metabolism ; Animals ; Cell Line ; Endoplasmic Reticulum Chaperone BiP ; Eukaryotic Initiation Factor-2/metabolism ; Fibroblasts ; Heat-Shock Proteins/metabolism ; Humans ; Listeria/immunology ; Membrane Proteins/metabolism ; Mice ; Mice, Mutant Strains ; Molecular Chaperones/metabolism ; Myeloid Differentiation Factor 88/metabolism ; Nod1 Signaling Adaptor Protein/chemistry ; Nod1 Signaling Adaptor Protein/metabolism ; Nod2 Signaling Adaptor Protein/metabolism ; Protein Serine-Threonine Kinases/genetics ; Salmonella/immunology ; Salmonella Infections ; Shigella/immunology ; Signal Transduction

المؤلفون: O'Meara TR; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada., Duah K; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada., Guo CX; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada., Maxson ME; Program in Cell Biology, Hospital for Sick Children, Toronto, Ontario, Canada., Gaudet RG; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada., Koselny K; Department of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA., Wellington M; Division of Pediatric Infectious Disease, University of Iowa, Iowa City, Iowa, USA., Powers ME; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, California, USA., MacAlpine J; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada., O'Meara MJ; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California, USA., Veri AO; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada., Grinstein S; Program in Cell Biology, Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada., Noble SM; Division of Pediatric Infectious Disease, University of Iowa, Iowa City, Iowa, USA., Krysan D; Department of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA., Gray-Owen SD; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada., Cowen LE; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada leah.cowen@utoronto.ca.

المصدر: MBio [mBio] 2018 Aug 21; Vol. 9 (4). Date of Electronic Publication: 2018 Aug 21.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101519231 Publication Model: Electronic Cited Medium: Internet ISSN: 2150-7511 (Electronic) NLM ISO Abbreviation: mBio Subsets: MEDLINE

مواضيع طبية MeSH: Genes, Fungal* , Host-Pathogen Interactions* , Pyroptosis*, Candida albicans/*genetics , Macrophages/*microbiology, Animals ; Candida albicans/pathogenicity ; Female ; High-Throughput Screening Assays ; Immune Evasion ; Macrophages/pathology ; Mice ; Mice, Inbred C57BL ; Phagocytosis

المؤلفون: Gall A; Molecular and Cellular Biology Graduate Program, University of Washington, Seattle, Washington, USA.; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Gaudet RG; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Howard Hughes Medical Institute and Departments of Microbial Pathogenesis and of Immunobiology, Yale University, New Haven, Connecticut, USA., Gray-Owen SD; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada., Salama NR; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA nsalama@fredhutch.org.; Department of Microbiology, University of Washington School of Medicine, Seattle, Washington, USA.

المصدر: MBio [mBio] 2017 Aug 15; Vol. 8 (4). Date of Electronic Publication: 2017 Aug 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101519231 Publication Model: Electronic Cited Medium: Internet ISSN: 2150-7511 (Electronic) NLM ISO Abbreviation: mBio Subsets: MEDLINE

مواضيع طبية MeSH: Signal Transduction*, Adaptor Proteins, Signal Transducing/*metabolism , Epithelial Cells/*microbiology , Gastric Mucosa/*metabolism , Gastric Mucosa/*microbiology , Helicobacter pylori/*immunology , Type IV Secretion Systems/*metabolism, Adaptor Proteins, Signal Transducing/genetics ; Antigens, Bacterial/metabolism ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Cell Line, Tumor ; Cytosol/metabolism ; Epithelial Cells/immunology ; Epithelial Cells/metabolism ; Gastric Mucosa/immunology ; Gastritis/immunology ; Gastritis/microbiology ; Genomic Islands ; Host-Pathogen Interactions ; Humans ; Immunity, Innate ; Lipopolysaccharides/biosynthesis ; NF-kappa B/metabolism ; Nod1 Signaling Adaptor Protein/genetics ; Nod1 Signaling Adaptor Protein/metabolism ; Tumor Necrosis Factor Receptor-Associated Peptides and Proteins/genetics ; Tumor Necrosis Factor Receptor-Associated Peptides and Proteins/metabolism

المؤلفون: Gaudet RG; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada., Guo CX; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada., Molinaro R; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A8, Canada., Kottwitz H; Departments of Microbiology and Immunology, Dalhousie University, Halifax, NS B3H 4R2, Canada., Rohde JR; Departments of Microbiology and Immunology, Dalhousie University, Halifax, NS B3H 4R2, Canada., Dangeard AS; INSERM, U1016, Institut Cochin, CNRS, UMR8104, Université Paris Descartes, Sorbonne Paris Cité, Paris 75014, France., Arrieumerlou C; INSERM, U1016, Institut Cochin, CNRS, UMR8104, Université Paris Descartes, Sorbonne Paris Cité, Paris 75014, France., Girardin SE; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A8, Canada., Gray-Owen SD; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address: scott.gray.owen@utoronto.ca.

المصدر: Cell reports [Cell Rep] 2017 May 16; Vol. 19 (7), pp. 1418-1430.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Immunity, Innate* , Signal Transduction*, Adaptor Proteins, Signal Transducing/*metabolism , Cytosol/*metabolism , Intracellular Space/*microbiology , Shigella flexneri/*growth & development, HeLa Cells ; Humans ; Nod1 Signaling Adaptor Protein/metabolism ; Phosphates/metabolism ; Vacuoles/metabolism

المؤلفون: Gaudet RG; Howard Hughes Medical Institute, Chevy Chase, MD 20815.; Yale Systems Biology Institute.; Departments of Microbial Pathogenesis and Immunobiology, Yale University School of Medicine, New Haven, CT 06520., Bradfield CJ; Howard Hughes Medical Institute, Chevy Chase, MD 20815.; Yale Systems Biology Institute.; Departments of Microbial Pathogenesis and Immunobiology, Yale University School of Medicine, New Haven, CT 06520., MacMicking JD; Howard Hughes Medical Institute, Chevy Chase, MD 20815.; Yale Systems Biology Institute.; Departments of Microbial Pathogenesis and Immunobiology, Yale University School of Medicine, New Haven, CT 06520.

المصدر: Microbiology spectrum [Microbiol Spectr] 2016 Dec; Vol. 4 (6).

نوع المنشور: Journal Article; Review; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: ASM Press Country of Publication: United States NLM ID: 101634614 Publication Model: Print Cited Medium: Internet ISSN: 2165-0497 (Electronic) Linking ISSN: 21650497 NLM ISO Abbreviation: Microbiol Spectr Subsets: MEDLINE

مواضيع طبية MeSH: Biological Evolution* , Microbial Viability* , Phagocytosis*, Macrophages/*immunology, Animals ; Humans

المؤلفون: Gaudet RG; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada., Gray-Owen SD; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.

المصدر: PLoS pathogens [PLoS Pathog] 2016 Sep 22; Vol. 12 (9), pp. e1005807. Date of Electronic Publication: 2016 Sep 22 (Print Publication: 2016).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog

المؤلفون: Gaudet RG; Department of Molecular Genetics, University of Toronto, Toronto, Canada M5S 1A8., Sintsova A; Department of Molecular Genetics, University of Toronto, Toronto, Canada M5S 1A8., Buckwalter CM; Department of Molecular Genetics, University of Toronto, Toronto, Canada M5S 1A8., Leung N; Department of Molecular Genetics, University of Toronto, Toronto, Canada M5S 1A8., Cochrane A; Department of Molecular Genetics, University of Toronto, Toronto, Canada M5S 1A8., Li J; Vaccine Program, National Research Council, Ottawa, ON, Canada K1A 0R6., Cox AD; Vaccine Program, National Research Council, Ottawa, ON, Canada K1A 0R6., Moffat J; Department of Molecular Genetics, University of Toronto, Toronto, Canada M5S 1A8. Donnelly Centre and Banting and Best Department of Medical Research, University of Toronto, Toronto, Canada M5S 3E1., Gray-Owen SD; Department of Molecular Genetics, University of Toronto, Toronto, Canada M5S 1A8. scott.gray.owen@utoronto.ca.

المصدر: Science (New York, N.Y.) [Science] 2015 Jun 12; Vol. 348 (6240), pp. 1251-5.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Immunity, Innate*, Adaptor Proteins, Signal Transducing/*immunology , Gram-Negative Bacteria/*immunology , Host-Pathogen Interactions/*immunology , Sugar Phosphates/*immunology, Adaptor Proteins, Signal Transducing/metabolism ; Burkholderia/immunology ; Cytosol/chemistry ; Cytosol/immunology ; Escherichia coli/immunology ; Flagellin/immunology ; Genetic Testing ; Gram-Negative Bacteria/metabolism ; HEK293 Cells ; Host-Pathogen Interactions/genetics ; Humans ; Jurkat Cells ; NF-kappa B/immunology ; Neisseria gonorrhoeae/immunology ; Neisseria meningitidis/immunology ; RNA Interference ; Sugar Phosphates/analysis ; Sugar Phosphates/metabolism ; TNF Receptor-Associated Factor 6/immunology ; TNF Receptor-Associated Factor 6/metabolism

المؤلفون: Malott RJ; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada M5S 1A8., Keller BO, Gaudet RG, McCaw SE, Lai CC, Dobson-Belaire WN, Hobbs JL, St Michael F, Cox AD, Moraes TF, Gray-Owen SD

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2013 Jun 18; Vol. 110 (25), pp. 10234-9. Date of Electronic Publication: 2013 Jun 03.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Gonorrhea*/immunology , Gonorrhea*/microbiology , Gonorrhea*/virology , HIV Infections*/immunology , HIV Infections*/microbiology , HIV Infections*/virology, Coinfection/*immunology , HIV-1/*enzymology , Heptoses/*immunology , Neisseria gonorrhoeae/*enzymology, Bacterial Proteins/genetics ; Bacterial Proteins/immunology ; Bacterial Proteins/metabolism ; CD4-Positive T-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/microbiology ; CD4-Positive T-Lymphocytes/virology ; Female ; HIV Long Terminal Repeat/genetics ; HIV-1/immunology ; Heptoses/genetics ; Heptoses/metabolism ; Humans ; Jurkat Cells ; Male ; Neisseria gonorrhoeae/immunology ; Toll-Like Receptor 5/immunology