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1دورية أكاديمية
المؤلفون: Jonathan Li, Ryan G. Lim, Julia A. Kaye, Victoria Dardov, Alyssa N. Coyne, Jie Wu, Pamela Milani, Andrew Cheng, Terri G. Thompson, Loren Ornelas, Aaron Frank, Miriam Adam, Maria G. Banuelos, Malcolm Casale, Veerle Cox, Renan Escalante-Chong, J. Gavin Daigle, Emilda Gomez, Lindsey Hayes, Ronald Holewenski, Susan Lei, Alex Lenail, Leandro Lima, Berhan Mandefro, Andrea Matlock, Lindsay Panther, Natasha Leanna Patel-Murray, Jacqueline Pham, Divya Ramamoorthy, Karen Sachs, Brandon Shelley, Jennifer Stocksdale, Hannah Trost, Mark Wilhelm, Vidya Venkatraman, Brook T. Wassie, Stacia Wyman, Stephanie Yang, Jennifer E. Van Eyk, Thomas E. Lloyd, Steven Finkbeiner, Ernest Fraenkel, Jeffrey D. Rothstein, Dhruv Sareen, Clive N. Svendsen, Leslie M. Thompson, Hemali Phatnani, PhD, Justin Kwan, MD, Dhruv Sareen, PhD, James R. Broach, PhD, Zachary Simmons, MD, Ximena Arcila-Londono, MD, Edward B. Lee, MD, PhD, Vivianna M. Van Deerlin, MD, PhD, Neil A. Shneider, MD, PhD, Ernest Fraenkel, PhD, Lyle W. Ostrow, MD, PhD, Frank Baas, MD, PhD, Noah Zaitlen, PhD, James D. Berry, MD, MPH, Andrea Malaspina, MD, PhD, Pietro Fratta, MD, PhD, Gregory A. Cox, PhD, Leslie M. Thompson, PhD, Steve Finkbeiner, MD, PhD, Efthimios Dardiotis, MD, PhD, Timothy M. Miller, MD, PhD, Siddharthan Chandran, PhD, Suvankar Pal, MD, Eran Hornstein, MD, PhD, Daniel J. MacGowan, MD, Terry Heiman-Patterson, MD, Molly G. Hammell, PhD, Nikolaos.A. Patsopoulos, MD, PhD, Oleg Butovsky, PhD, Joshua Dubnau, PhD, Avindra Nath, MD, Robert Bowser, PhD, Matt Harms, MD, Mary Poss, DVM, PhD, Jennifer Phillips-Cremins, PhD, John Crary, MD, PhD, Nazem Atassi, MD, Dale J. Lange, MD, Darius J. Adams, MD, Leonidas Stefanis, MD, PhD, Marc Gotkine, MD, Robert H. Baloh, MD. PhD, Suma Babu, MBBS, MPH, Towfique Raj, PhD, Sabrina Paganoni, MD, PhD, Ophir Shalem, PhD, Colin Smith, MD, Bin Zhang, PhD, Brent Harris, MD, PhD, Iris Broce, PhD, Vivian Drory, MD, John Ravits, MD, Corey McMillan, PhD, Vilas Menon, PhD, Lani Wu, PhD, Steven Altschuler, PhD
المصدر: iScience, Vol 24, Iss 11, Pp 103221- (2021)
مصطلحات موضوعية: Biological sciences, Neuroscience, Systems neuroscience, Systems biology, Omics, Science
وصف الملف: electronic resource
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المؤلفون: J. Gavin Daigle, Dwight E. Bergles, Raha Dastgheyb, Jeannie Chew, Svetlana Vidensky, Malika S Datta, Rita Sattler, Namho Kim, Justin Hanes, Yi Chun Hsieh, Mikhail V. Pletnikov, Jeffrey D. Rothstein, Michael B. Robinson, Raju Tomer, Norman J. Haughey, Thomas Philips, Jung Soo Suk, Zhuoxun Chen, Jacqueline T. Pham, Sean J. Miller, Ethan G. Hughes
المصدر: Nature neuroscience
مصطلحات موضوعية: 0301 basic medicine, Genetically modified mouse, Male, Dendritic spine, Transgene, Dendritic Spines, Mice, Transgenic, Nerve Tissue Proteins, Biology, Article, Receptors, G-Protein-Coupled, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, Premovement neuronal activity, Animals, Humans, Secretion, Gray Matter, Receptor, Eye Proteins, Cells, Cultured, Cerebral Cortex, Neurons, LGR6, General Neuroscience, Motor Cortex, Mice, Inbred C57BL, 030104 developmental biology, nervous system, Astrocytes, Neuroscience, 030217 neurology & neurosurgery
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المؤلفون: Nicholas A. Clark, Marc R. Birtwistle, Jennifer E. Van Eyk, Moshe C. Silverstein, Caitlin E. Mills, Mario Niepel, Marcin Pilarczyk, Alexander Lachmann, Elizabeth H. Williams, Simon Koplev, Nathanael S. Gray, Uzma Hussain, Albert Lee, Ajay Pillai, Edward He, Mark A. Dane, Evren U. Azeloglu, Dusica Vidovic, Jeannette Osterloh, Maria G. Banuelos, Maxim V. Kuleshov, Rick J. Koch, Stephan C. Schürer, Karen Sachs, Damir Sudar, Divya Ramamoorthy, Dhruv Sareen, Shana White, Heidi S. Feiler, Siva Sivaganesan, Kathleen M. Jagodnik, Clive N. Svendsen, Mohammad Fallahi-Sichani, Miriam Adam, Jaroslaw Meller, Todd R. Golub, Ravi Iyengar, Jennifer Stocksdale, Amar Koleti, David Wrobel, Sherry L. Jenkins, Jacob D. Jaffe, Alexandra B Keenan, Renan Escalante-Chong, Daniel J. Cooper, Loren Ornelas, Joe W. Gray, Alexander LeNail, Ritchie Ho, Alyssa Coye, Avi Ma'ayan, Steve Finkbiener, Lixia Zhang, Andrea Matlock, Eric A. Sobie, Vidya Venkatraman, Anders B. Dohlman, Jeffrey D. Rothstein, Michele Forlin, Jonathan Z. Li, Rebecca Smith, Naim Al Mahi, Kaylyn Devlin, Caty Chung, Marc Hafner, Malvina Papanastasiou, Wen Niu, Michal Kouril, Ryan G. Lim, Yan Ren, Julia A. Kaye, Malcolm Casale, Jie Wu, Mario Medvedovic, Jeremy L. Muhlich, Victoria Dardov, Jouzas Vasiliauskas, Kelly Haston, Caroline E. Shamu, Raymond Terryn, John F. Reichard, Michel Nederlof, David Kilburn, Leslie M. Thompson, Jia-Ren Lin, Vasileios Stathias, Zichen Wang, Behrouz Shamsaei, James E. Korkola, Pamela Milani, Berhan Mandefro, Terri G. Thompson, Laura M. Heiser, Gavin Daigle, Denis Torre, Ron Margolis, Aravind Subramanian, Elmar Bucher, Sean D. Erickson, Ernest Fraenkel, Jaslin Kalra, Mark A. LaBarge, Gordon B. Mills, Peter K. Sorger, Sean M. Gross, Leslie Derr, Mehdi Fazel
المصدر: Cell Systems. 6:13-24
مصطلحات موضوعية: 0301 basic medicine, Histology, National Health Programs, Computer science, Systems biology, Information Storage and Retrieval, Cataloging, Transcript profiling, Computational biology, Imaging data, Article, Pathology and Forensic Medicine, World Wide Web, 03 medical and health sciences, Human disease, Common fund, System level, Humans, Gene Library, Gene Expression Profiling, Systems Biology, Computational Biology, Cell Biology, United States, 030104 developmental biology, National Institutes of Health (U.S.), Transcriptome, Databases, Chemical, Systems pharmacology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2e6db8bbc9afc2e0643a000d0253b2b
https://doi.org/10.1016/j.cels.2017.11.001 -
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المؤلفون: Casey Cook, Svetlana Vidensky, Rachel E. Bennett, Jeffrey D. Rothstein, Charles R. Vanderburg, Fred H. Gage, Michael DeTure, Susanne Wegmann, Roderick Y. H. Lim, Leonard Petrucelli, Bahareh Eftekharzadeh, Xavier Salvatella, Juan C. Troncoso, Jerome Mertens, Larisa E. Kapinos, Eckhard Mandelkow, Simon Dujardin, J. Gavin Daigle, Bianca T. Corjuc, Jose J. Gonzalez, Yari Carlomagno, Alyssa N. Coyne, Sean J. Miller, Bradley T. Hyman, Ana S. Amaral, Jonathan C. Grima, Katharina Tepper, Jeannie Chew, Julia Schiantarelli, Sarah L. DeVos
المصدر: Neuron 99(5), 925-940.e7 (2018). doi:10.1016/j.neuron.2018.07.039
مصطلحات موضوعية: Male, 0301 basic medicine, Genetically modified mouse, pathology [Cytoplasm], Tau protein, Active Transport, Cell Nucleus, physiology [Active Transport, Cell Nucleus], genetics [Alzheimer Disease], Mice, Transgenic, tau Proteins, Article, pathology [Alzheimer Disease], Mice, 03 medical and health sciences, 0302 clinical medicine, Alzheimer Disease, mental disorders, medicine, Animals, Humans, ddc:610, metabolism [Cell Nucleus], Nuclear pore, metabolism [Cytoplasm], 030304 developmental biology, 0303 health sciences, biology, General Neuroscience, Neurotoxicity, Nuclear Proteins, medicine.disease, metabolism [tau Proteins], Cell biology, 030104 developmental biology, medicine.anatomical_structure, Tauopathies, Nucleocytoplasmic Transport, pathology [Cell Nucleus], biology.protein, Female, Nucleoporin, Neuron, Nuclear transport, metabolism [Alzheimer Disease], Function (biology), 030217 neurology & neurosurgery
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e840905c53dddd18d9210e43dc2063b5
https://europepmc.org/articles/PMC6240334/ -
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المؤلفون: Bradley T. Hyman, J. Gavin Daigle, Nicholas J. Valle, Rachel E. Bennett, Sarah L. DeVos, Svetlana Vidensky, Ana C. Amaral, Casey Cook, Jeffrey D. Rothstein, Caitlin Commins, Xavier Salvatella, Danny MacKenzie, Eckhard Mandelkow, Roderick Y. H. Lim, Susanne Wegmann, Larisa E. Kapinos, Juan C. Troncoso, Jerome Mertens, Sean J. Miller, Julia Schiantarelli, Jonathan C. Grima, Bahareh Eftekharzadeh, Fred H. Gage, Katharina Tepper, Charles R. Vanderburgh, Leonard Petrucelli, Alyssa N. Coyne, Bianca T. Corjuc, Uzma Hussain, Jose J. Gonzalez, Yari Carlomagno, Masato Maesako, Simon Dujardin
المصدر: SSRN Electronic Journal.
مصطلحات موضوعية: Genetically modified mouse, biology, Chemistry, Tau protein, Neurotoxicity, medicine.disease, Cell biology, Microtubule, Nucleocytoplasmic Transport, mental disorders, biology.protein, medicine, Nuclear pore, Nuclear export signal, Function (biology)
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8bbb03579de4710a4b06e34855174b49
https://doi.org/10.2139/ssrn.3155576 -
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المؤلفون: Zhinong Huang, Zhe Wang, Olugbenga M. Doherty, Iyare Izevbaye, Dean G. Stathakis, Jerrad Thomas, J. Gavin Daigle, Janis M. O'Donnell, Faiza Ferdousy, Hakeem Lawal
المصدر: Journal of Neurochemistry. 119:1294-1305
مصطلحات موضوعية: medicine.medical_specialty, Tyrosine hydroxylase, GTP cyclohydrolase I, Dopaminergic, Neurodegeneration, Substantia nigra, Biology, medicine.disease, Biochemistry, Neuroprotection, Vesicular monoamine transporter, Cellular and Molecular Neuroscience, Endocrinology, Dopamine, Internal medicine, medicine, biology.protein, medicine.drug
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المؤلفون: Ke Zhang, Aaron D. Gitler, J. Paul Taylor, Kai Ruan, Jonathan C. Grima, Jeffrey D. Rothstein, Peiguo Yang, Thomas E. Lloyd, Alyssa N. Coyne, Harsh Wadhwa, J. Gavin Daigle, Frank Rigo, Kathleen M. Cunningham, Kelly Bowen
المصدر: Cell. 173:958-971.e17
مصطلحات موضوعية: Male, alpha Karyopherins, 0301 basic medicine, Arsenites, Active Transport, Cell Nucleus, Biology, Protein aggregation, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Stress granule, C9orf72, medicine, Humans, Stress granule assembly, RNA, Small Interfering, Amyotrophic lateral sclerosis, Aged, Ataxin-2, DNA Repeat Expansion, Membrane Glycoproteins, C9orf72 Protein, Amyotrophic Lateral Sclerosis, Neurodegeneration, Middle Aged, beta Karyopherins, medicine.disease, Sodium Compounds, Cell biology, Nuclear Pore Complex Proteins, Oxidative Stress, HEK293 Cells, ran GTP-Binding Protein, 030104 developmental biology, Nucleocytoplasmic Transport, Frontotemporal Dementia, Female, RNA Interference, Trinucleotide repeat expansion
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3abad46483237431ad11f097070c48fe
https://doi.org/10.1016/j.cell.2018.03.025 -
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المؤلفون: Earl W. Godfrey, Kevin McAvoy, Karthik Krishnamurthy, Dianne C. Daniel, J. Gavin Daigle, Edward M. Johnson, Piera Pasinelli, Nandini Ramesh, Ian Casci, John Monaghan, Frank Shewmaker, Udai Bhan Pandey, Zachary T. Monahan
المصدر: Acta neuropathologica. 131(4)
مصطلحات موضوعية: 0301 basic medicine, Male, Pathology, RNA-binding protein, Rats, Sprague-Dawley, 0302 clinical medicine, Amyotrophic lateral sclerosis, Enzyme Inhibitors, RNA, Small Interfering, Poly-ADP-Ribose Binding Proteins, Cells, Cultured, Motor Neurons, Cytoplasmic stress granule, Neurodegeneration, Brain, Sodium Compounds, Cell biology, Anti-Bacterial Agents, DNA-Binding Proteins, RNA Recognition Motif Proteins, Doxycycline, Female, Microtubule-Associated Proteins, RNA Helicases, medicine.medical_specialty, Arsenites, Biology, Cytoplasmic Granules, Article, Pathology and Forensic Medicine, 03 medical and health sciences, Cellular and Molecular Neuroscience, Stress granule, medicine, Animals, Humans, Amyotrophic Lateral Sclerosis, DNA Helicases, medicine.disease, Embryo, Mammalian, Rats, 030104 developmental biology, Gene Expression Regulation, Cell culture, RNA-Binding Protein FUS, Ectopic expression, Neurology (clinical), Carrier Proteins, 030217 neurology & neurosurgery, Transcription Factors
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المؤلفون: Jenna C. Glatzer, Jennifer Stocksdale, Laura P.W. Ranum, Wenzhen Duan, Nicolas Arbez, Ke Zhang, Jonathan C. Grima, Qi Peng, Juan C. Troncoso, Jeffrey D. Rothstein, Christopher A. Ross, Leslie M. Thompson, Kathleen C. Cunningham, J. Gavin Daigle, Harsh Wadhwa, Ishrat Ahmed, Charlene Geater, Solomon H. Snyder, Eva L. Morozko, Jacqueline T. Pham, Olga Pletnikova, Joseph Ochaba, Thomas E. Lloyd
المصدر: Neuron, vol 94, iss 1
مصطلحات موضوعية: Male, Huntington's Disease, 0301 basic medicine, induced pluripotent stem cell, Huntingtin, Neurodegenerative, Mice, Drosophila Proteins, 2.1 Biological and endogenous factors, Psychology, Aetiology, Nuclear pore, Huntingtin Protein, nucleocytoplasmic transport, General Neuroscience, Neurodegeneration, neurodegeneration, Middle Aged, Active Transport, Cell biology, Huntington Disease, Neurological, Drosophila, Female, Cognitive Sciences, Nucleoporin, Huntington’s disease, Adult, Induced Pluripotent Stem Cells, Active Transport, Cell Nucleus, Thiamet-G, C9ORF72, Biology, Article, Young Adult, 03 medical and health sciences, Rare Diseases, Huntington's disease, RAN translation, nuclear pore complex, medicine, Animals, Humans, KPT-350, Cell Nucleus, Neurology & Neurosurgery, Animal, Neurosciences, medicine.disease, Molecular biology, Brain Disorders, Nuclear Pore Complex Proteins, Disease Models, Animal, Orphan Drug, 030104 developmental biology, Nucleocytoplasmic Transport, Disease Models, Mutation, Ran, Nuclear Pore, O-GlcNAc
وصف الملف: application/pdf
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المؤلفون: Lindsay R. Roberts, Adam L. Knight, J. Gavin Daigle, Joseph R. Mazzulli, Shusei Hamamichi, Coralie Viollet-Djelassi, Akeem R. Borom, Guy A. Caldwell, S. Kyle Lee, Susan M. DeLeon, Xiaohui Yan, Kim A. Caldwell, Siyuan Zhang, Rami R. Ajjuri, Dimitri Krainc, Mike W. Zhang, Janis M. O'Donnell
المصدر: Cell metabolism. 20(1)
مصطلحات موضوعية: Male, Aging, Physiology, Biology, Neuroprotection, Article, chemistry.chemical_compound, Mice, RNA interference, medicine, Animals, Drosophila Proteins, Insulin-Like Growth Factor I, RNA, Small Interfering, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Transcription factor, Molecular Biology, Cells, Cultured, Alpha-synuclein, Genetics, Dopaminergic Neurons, Neurodegeneration, Dopaminergic, fungi, Glucose-6-Phosphate Isomerase, Forkhead Transcription Factors, Parkinson Disease, Cell Biology, medicine.disease, Receptor, Insulin, Cell biology, Disease Models, Animal, Proteostasis, Glucose, chemistry, Proteotoxicity, Insulin Receptor Substrate Proteins, alpha-Synuclein, Cytokines, Drosophila, RNA Interference, Glycolysis, Signal Transduction, Transcription Factors
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