المؤلفون: Katarina Kulhankova, Soumba Traore, Xue Cheng, Hadrien Benk-Fortin, Stéphanie Hallée, Mario Harvey, Joannie Roberge, Frédéric Couture, Sajeev Kohli, Thomas J. Gross, David K. Meyerholz, Garrett R. Rettig, Bernice Thommandru, Gavin Kurgan, Christine Wohlford-Lenane, Dennis J. Hartigan-O’Connor, Bradley P. Yates, Gregory A. Newby, David R. Liu, Alice F. Tarantal, David Guay, Paul B. McCray

المصدر: Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/8ac54f1857804245a0069d9ef38b1f91

المؤلفون: Mollie S. Schubert, Bernice Thommandru, Jessica Woodley, Rolf Turk, Shuqi Yan, Gavin Kurgan, Matthew S. McNeill, Garrett R. Rettig

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/beb41c1f9a884d0690dce2597cdadd0e

المؤلفون: Gavin Kurgan, Rolf Turk, Heng Li, Nathan Roberts, Garrett R. Rettig, Ashley M. Jacobi, Lauren Tso, Morgan Sturgeon, Massimo Mertens, Roel Noten, Kurt Florus, Mark A. Behlke, Yu Wang, Matthew S. McNeill

المصدر: Molecular Therapy: Methods & Clinical Development, Vol 21, Iss , Pp 478-491 (2021)

مصطلحات موضوعية: CRISPR, Cas9, Cas12a, bioinformatics, amplicon sequencing, genome editing, Genetics, QH426-470, Cytology, QH573-671

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050121000644; https://doaj.org/toc/2329-0501

URL الوصول: https://doaj.org/article/5e209aed7e8a4ef2be494827ee71b257

المؤلفون: Ido Amit, Ortal Iancu, Alona Levy-Jurgenson, Gavin Kurgan, Matthew S. McNeill, Garrett R. Rettig, Daniel Allen, Dor Breier, Nimrod Ben Haim, Yu Wang, Leon Anavy, Ayal Hendel, Zohar Yakhini

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/a5eef4e669634506b9f9db24ef9fe0fe

المؤلفون: Raviraj Banakar, Mollie Schubert, Gavin Kurgan, Krishan Mohan Rai, Sarah F. Beaudoin, Michael A. Collingwood, Christopher A. Vakulskas, Kan Wang, Feng Zhang

المصدر: Frontiers in Genome Editing, Vol 3 (2022)

مصطلحات موضوعية: Nicotiana benthamiana, pennycress, protoplast, ribonucleoprotein, Setaria viridis, soybean, Biotechnology, TP248.13-248.65, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fgeed.2021.760820/full; https://doaj.org/toc/2673-3439

URL الوصول: https://doaj.org/article/18bff289bbd546329b3e1e0d0936c3a5

المؤلفون: Jessica Woodley, Shuqi Yan, Matthew S. McNeill, Garrett R. Rettig, Gavin Kurgan, Mollie S. Schubert, Bernice Thommandru, Rolf Turk

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports

مصطلحات موضوعية: Computer science, Science, CRISPR-Associated Proteins, Computational biology, medicine.disease_cause, Article, Cell Line, Homology directed repair, Bacterial Proteins, CRISPR-Associated Protein 9, medicine, Humans, CRISPR, Non-homologous-end joining, Guide RNA, Homologous recombination, Gene Editing, Mutation, Endodeoxyribonucleases, Multidisciplinary, Cas9, Recombinational DNA Repair, Non-homologous end joining, Template, Medicine, CRISPR-Cas Systems, RNA, Guide, Kinetoplastida

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0be0b3603fc8a3f009c82f9b4f7e44be
https://doaj.org/article/beb41c1f9a884d0690dce2597cdadd0e

المؤلفون: Mark A. Behlke, Yu Wang, Lauren Tso, Nathan Roberts, Matthew S. McNeill, Gavin Kurgan, Morgan Sturgeon, Heng Li, Roel Noten, Ashley M. Jacobi, Massimo Mertens, Garrett R. Rettig, Kurt Florus, Rolf Turk

المصدر: Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss, Pp 478-491 (2021)

مصطلحات موضوعية: 0301 basic medicine, Computer science, DNA repair, Computational biology, QH426-470, non-homologous end joining, 03 medical and health sciences, 0302 clinical medicine, Software, Genome editing, Genetics, CRISPR, genome editing, Guide RNA, Cas9, Molecular Biology, QH573-671, Cas12a, amplicon sequencing, business.industry, bioinformatics, Double Strand Break Repair, 030104 developmental biology, 030220 oncology & carcinogenesis, Molecular Medicine, Original Article, User interface, Cytology, business, off-target analysis, next-generation sequencing software

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb0e71b10793ebd9a5eee2a52efcf87a
http://europepmc.org/articles/PMC8082044

المؤلفون: Renata M. Martin, Waracharee Srifa, Ravindra Majeti, Ezequiel Ponce, Daniel P. Dever, Yankai Zhang, Benjamin J. Lesch, Matthew H. Porteus, Garrett R. Rettig, Vivien A. Sheehan, Feifei Zhao, Mark A. Behlke, Michael A. Collingwood, Christopher A. Vakulskas, Nicole M. Bode, Gavin Kurgan, M. Kyle Cromer, Rasmus O. Bak, Viktor T. Lemgart, Ankush Goyal, Naoya Uchida, Joab Camarena, John F. Tisdale

المصدر: Nat Med
Cromer, M K, Camarena, J, Martin, R M, Lesch, B J, Vakulskas, C A, Bode, N M, Kurgan, G, Collingwood, M A, Rettig, G R, Behlke, M A, Lemgart, V T, Zhang, Y, Goyal, A, Zhao, F, Ponce, E, Srifa, W, Bak, R O, Uchida, N, Majeti, R, Sheehan, V A, Tisdale, J F, Dever, D P & Porteus, M H 2021, ' Gene replacement of α-globin with β-globin restores hemoglobin balance in β-thalassemia-derived hematopoietic stem and progenitor cells ', Nature Medicine, vol. 27, no. 4, pp. 677-687 . https://doi.org/10.1038/s41591-021-01284-y

مصطلحات موضوعية: 0301 basic medicine, Erythrocytes, Transgene, Thalassemia, medicine.medical_treatment, Antigens, CD34, Anemia, Sickle Cell, beta-Globins, Hematopoietic stem cell transplantation, Biology, Article, General Biochemistry, Genetics and Molecular Biology, Hemoglobins, Mice, 03 medical and health sciences, 0302 clinical medicine, alpha-Globins, Genes, Reporter, hemic and lymphatic diseases, medicine, Animals, Humans, Globin, Progenitor cell, Promoter Regions, Genetic, Gene Editing, Messenger RNA, beta-Thalassemia, Hematopoietic Stem Cell Transplantation, Genetic Therapy, General Medicine, Dependovirus, Hematopoietic Stem Cells, medicine.disease, Cell biology, Haematopoiesis, 030104 developmental biology, Genetic Loci, 030220 oncology & carcinogenesis, Hemoglobin, RNA, Guide, Kinetoplastida

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a78fed0c19389bd72360d35b2f89a625
https://doi.org/10.1038/s41591-021-01284-y

المؤلفون: Nedyalko Petrov, Junjun Lu, Ana Karen Nunez Cortes, Mustafa H Bdiwi, Matthew S. McNeill, Lorenzo Brunetti, Li Li, Gonca Ozcan, Nobuhiko Imahashi, Ken Chen, Mollie S. Schubert, Duncan Mak, Lucila Nassif Kerbauy, Mark A. Behlke, Luis Muniz-Feliciano, Leiser Silva, Elizabeth J. Shpall, Enli Liu, Ali Rezvan, Natalie W. Fowlkes, Elif Gokdemir, Garrett R. Rettig, Richard Skinner, Xin Ru Jiang, Jing Wang, Vakul Mohanty, Mohsen Fathi, Yifei Shen, Yuanxin Xi, Mayela Mendt, Shahram Kordasti, Natalia Baran, Francesca Lorraine Wei Inng Lim, Nadima Uprety, Sonny Ang, Sunil Acharya, Pinaki P. Banerjee, Marina Konopleva, May Daher, Richard E. Champlin, Gavin Kurgan, Heng Li, Hila Shaim, Rolf Turk, Mecit Kaplan, Xinhai Wan, Mayra Shanley, Emily Ensley, David Marin, Rafet Basar, Navin Varadarajan, Shangrong Lyu, Katayoun Rezvani, Ye Li, Vandana Nandivada

المصدر: 2021, ' Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells ', Blood, vol. 137, no. 5, pp. 624–636 . https://doi.org/10.1182/blood.2020007748

مصطلحات موضوعية: Cell cycle checkpoint, medicine.medical_treatment, Antigens, CD19, Immunology, Suppressor of Cytokine Signaling Proteins, mTORC1, Mechanistic Target of Rapamycin Complex 1, Biology, Immunotherapy, Adoptive, Biochemistry, Gene Knockout Techniques, Mice, Cancer immunotherapy, Cell Line, Tumor, medicine, Animals, Humans, Immune Checkpoint Inhibitors, Interleukin-15, Receptors, Chimeric Antigen, Cell Biology, Hematology, Immunotherapy, Fetal Blood, Burkitt Lymphoma, Xenograft Model Antitumor Assays, Aerobiosis, Immune checkpoint, Chimeric antigen receptor, Neoplasm Proteins, Killer Cells, Natural, Cytokine, Interleukin 15, Cancer research, CRISPR-Cas Systems, Glycolysis, Proto-Oncogene Proteins c-akt, Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f4e7a129bf19a18d393b5db7c33c686
https://doi.org/10.1182/blood.2020007748

المؤلفون: Moses Onyeabor, Xuan Wang, Eric Taylor, Logan Kurgan, Steven C. Holland, Aidan Schneider, Tommy Billings, Gavin Kurgan

المصدر: Journal of Industrial Microbiology and Biotechnology. 49

مصطلحات موضوعية: Zymomonas, Xylose, biology, Mutagenesis, Biomass, Lignocellulosic biomass, Bioengineering, biology.organism_classification, Directed evolution, Applied Microbiology and Biotechnology, Zymomonas mobilis, chemistry.chemical_compound, Glucose, chemistry, Biochemistry, Fermentation, Escherichia coli, Sugars, Sugar, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5bb3cabbd8c4a5a51743761fa2896e0
https://doi.org/10.1093/jimb/kuab066