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1
المؤلفون: Andrew D. Mesecar, Thippeswamy Devasamudram, Xiao Ming Xu, Jordan Tang, Yu-Chen Yen, Xiangping Huang, Gerald Koelsch, Arun K. Ghosh, Geoffrey Bilcer, Margherita Brindisi, Hui Lei
المساهمون: Ghosh, Arun K., Brindisi, Margherita, Yen, Yu Chen, Xu, Xiaoming, Huang, Xiangping, Devasamudram, Thippeswamy, Bilcer, Geoffrey, Lei, Hui, Koelsch, Gerald, Mesecar, Andrew D., Tang, Jordan
المصدر: Bioorganic & Medicinal Chemistry Letters. 25:668-672
مصطلحات موضوعية: Protease Inhibitor, Clinical Biochemistry, Pharmaceutical Science, Pyrazole, Crystallography, X-Ray, Ligands, Biochemistry, chemistry.chemical_compound, Catalytic Domain, Drug Discovery, β-secretase, Moiety, Amyloid Precursor Protein Secretase, Alzheimer's disease, BACE-1, Memapsin 2, Protease inhibitors, Amyloid Precursor Protein Secretases, Binding Sites, Kinetics, Molecular Dynamics Simulation, Protease Inhibitors, Protein Binding, Pyrazoles, Structure-Activity Relationship, Thiazoles, Drug Design, Molecular Medicine, Molecular Biology, 3003, Drug Discovery3003 Pharmaceutical Science, Organic Chemistry, Crystallography, biology, Stereochemistry, Ligand, Article, Structure–activity relationship, Binding site, Thiazole, Kinetic, Binding Site, Active site, Combinatorial chemistry, chemistry, X-Ray, biology.protein, Amyloid precursor protein secretase
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2
المؤلفون: Gerald Koelsch, Arun K. Ghosh, Lin Hong, Jordan Tang, Geoffrey Bilcer
المصدر: Current Alzheimer Research. 4:418-422
مصطلحات موضوعية: Drug, Proteases, media_common.quotation_subject, Memapsin-2, Disease, Pharmacology, Alzheimer Disease, Animals, Aspartic Acid Endopeptidases, Humans, Medicine, Protease inhibitor (pharmacology), Enzyme Inhibitors, media_common, biology, business.industry, medicine.disease, Clinical trial, Models, Chemical, Neurology, biology.protein, Neurology (clinical), Amyloid Precursor Protein Secretases, Alzheimer's disease, business, Amyloid precursor protein secretase
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9e8692c57d91145fbbb47cb887a9c45
https://doi.org/10.2174/156720507781788864 -
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المؤلفون: Thippeswamy Devasamudram, Christopher B. DeZutter, Vajira Weerasena, Lin Hong, Jordan Tang, Gerald Koelsch, Geoffrey Bilcer, Xiaoming Xu, Arun K. Ghosh
المصدر: Bioorganic & Medicinal Chemistry Letters. 15:15-20
مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Substituent, Pharmaceutical Science, Crystallography, X-Ray, Urethane, Biochemistry, Chemical synthesis, chemistry.chemical_compound, Endopeptidases, Drug Discovery, Hydrolase, Amyloid precursor protein, Aspartic Acid Endopeptidases, Humans, Protease Inhibitors, Molecular Biology, Molecular Structure, biology, Organic Chemistry, Brain, Amides, Ring size, chemistry, Enzyme inhibitor, biology.protein, Lactam, Molecular Medicine, Amyloid Precursor Protein Secretases, Amyloid precursor protein secretase
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المؤلفون: Yuefang Wang, and Paraskevi Giannakakou, Arun K. Ghosh, J. Fernando Díaz, José Manuel Andreu, Mikio Kabaki, Donald E. Pryor, Yong Wang, Aurora O'Brate, Geoffrey Bilcer, M. Katherine Jung, Ernest Hamel
المصدر: Biochemistry. 41:9109-9115
مصطلحات موضوعية: Models, Molecular, Epothilones, Binding Sites, Natural product, Paclitaxel, biology, Eleutherobin, Stereochemistry, Fluorescence Polarization, Tritium, Microtubules, Biochemistry, Taxoid, chemistry.chemical_compound, Tubulin, chemistry, Drug Resistance, Neoplasm, Microtubule, biology.protein, Epoxy Compounds, Moiety, Taxoids, Macrolides
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المؤلفون: Raymond T. Ng, Kelvin W. Gee, Leonard T. Meltzer, Ryan F. Yoshimura, Geoffrey Bilcer, Patrick M. Callahan, Terence A. Kelly, Alvin V. Terry, Gerald Koelsch, John Ng
المصدر: Alzheimer's & Dementia. 10
مصطلحات موضوعية: Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, media_common.quotation_subject, Neurology (clinical), Art, Geriatrics and Gerontology, Partial agonist, Humanities, media_common
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المؤلفون: Jordan Tang, Dongwoo Shin, Geoffrey Bilcer, Cynthia J. Harwood, Jeffrey A. Loy, Lin Hong, Reiko Kawahama, Chan Nguyen, Arun K. Ghosh, Jacques Ermolieff, Gerald Koelsch, Khaja Azhar Hussain
المصدر: Journal of Medicinal Chemistry. 44:2865-2868
مصطلحات موضوعية: Models, Molecular, Proteases, Peptide, Crystallography, X-Ray, Structure-Activity Relationship, chemistry.chemical_compound, Endopeptidases, Drug Discovery, Peptide synthesis, Aspartic Acid Endopeptidases, Humans, Structure–activity relationship, Protease Inhibitors, chemistry.chemical_classification, Oligopeptide, biology, Tetrapeptide, Molecular Weight, chemistry, Biochemistry, Enzyme inhibitor, Drug Design, biology.protein, Molecular Medicine, Amyloid Precursor Protein Secretases, Oligopeptides, Amyloid precursor protein secretase
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المؤلفون: Gary E. Schiltz, Geoffrey Bilcer, Arun K. Ghosh
المصدر: Synthesis. 2001:2203-2229
مصطلحات موضوعية: Protease, Peptidomimetic, Isostere, Chemistry, medicine.medical_treatment, Organic Chemistry, Human immunodeficiency virus (HIV), Pharmacology, medicine.disease_cause, medicine.disease, Article, Catalysis, Food and drug administration, Aspartate protease, Acquired immunodeficiency syndrome (AIDS), medicine, HIV Protease Inhibitor
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b757985c20079c5ec254664ba6967e8
https://doi.org/10.1055/s-2001-18434 -
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المؤلفون: Geoffrey Bilcer, Arun K. Ghosh, Elena S. Koltun
المصدر: Synthesis. 2001:1281-1301
مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Bioactive molecules, Organic Chemistry, Synthon, Tartaric acid, Organic chemistry, Tartrate, Article, Catalysis
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ed45ecb56e1c8eb76eaba8ede14f7d4
https://doi.org/10.1055/s-2001-15217 -
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المؤلفون: Olivier Dasse, Minhtam B. Tran, Ryan F. Yoshimura, Terence A. Kelly, Geoffrey Bilcer, David Putman, Gerald Koelsch, Timothy B C Johnstone, Raymond T. Ng, Kelvin W. Gee, Karen E. Stevens
المصدر: Biochemical Pharmacology. 97:636
مصطلحات موضوعية: Pharmacology, Allosteric modulator, Chemistry, Biochemistry, α7 nachr
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المؤلفون: Karen E. Stevens, Paul C. Anderson, Patrick M. Callahan, Alvin V. Terry, Michael J. Detke, Leonard T. Meltzer, Geoffrey Bilcer, Terence A. Kelly, Gerald Koelsch, Raymond T. Ng, John Ng, Ryan F. Yoshimura
المصدر: Biochemical Pharmacology. 97:636
مصطلحات موضوعية: Pharmacology, Nicotinic agonist, Ganglion type nicotinic receptor, Chemistry, Muscarinic acetylcholine receptor, Muscarinic acetylcholine receptor M4, Muscarinic acetylcholine receptor M3, Muscarinic acetylcholine receptor M2, Alpha-4 beta-2 nicotinic receptor, Biochemistry, Acetylcholine receptor
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