-
1
المؤلفون: Jin Wang, Andrea Hall, Geoffrey W. Henson, Brenda Ames, Mohamed Aljarah, Andrea Brancale, Elena Gorovits, Arnaud Gilles, John Vernachio, Karolina Madela, Babita Ganguly, Stanley D. Chamberlain, Jerry Muhammad, Nicola Zonta, Joseph M. Patti, Jeff T. Hutchins, Christopher McGuigan, Alexander A. Kolykhalov
المصدر: Bioorganic & Medicinal Chemistry Letters. 20:4850-4854
مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Guanosine Monophosphate, Pharmaceutical Science, Guanosine, Protide, Hepacivirus, Guanosine triphosphate, Antiviral Agents, Biochemistry, chemistry.chemical_compound, Drug Discovery, Humans, Phosphoric Acids, Prodrugs, Replicon, Molecular Biology, Cells, Cultured, Chemistry, Organic Chemistry, Phosphoramidate, Nucleotidyltransferase, Amides, Drug Design, Molecular Medicine, Guanine nucleoside, Nucleoside
-
2
المؤلفون: Andrea Hall, Christopher McGuigan, K. Dawn Bryant, Babita Ganguly, Arnaud Gilles, Robin Walters, Jerry Muhammad, John Vernachio, Mohamed Aljarah, Nicholas Raja, Elena Gorovits, Geoffrey W. Henson, Jin Wang, Sabrina Holl, Damound Hunley, Brenda Ames, Alexander A. Kolykhalov, Stanley D. Chamberlain, Karolina Madela, Yule Liu, Sarah Jones, Jeff T. Hutchins
المصدر: Journal of Medicinal Chemistry. 53:4949-4957
مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Hepatitis C virus, Protide, Hepacivirus, Virus Replication, medicine.disease_cause, Antiviral Agents, Cell Line, Mice, Adenosine Triphosphate, In vivo, Drug Discovery, medicine, Animals, Humans, Phosphoric Acids, Polymerase, chemistry.chemical_classification, Mice, Inbred ICR, Guanosine, biology, Chemistry, Phosphoramidate, Amides, Hepatitis C, In vitro, Amino acid, Liver, Biochemistry, biology.protein, Molecular Medicine, Female, Nucleoside
-
3Leukocytosis and Mobilization of CD34+ Hematopoietic Progenitor Cells by AMD3100, a CXCR4 Antagonist
المؤلفون: Scott Cooper, Gary Calandra, Brent L. Wood, Ron MacFarland, Hal E. Broxmeyer, W. Conrad Liles, Gary Bridger, Elin Rodger, Kai Hübel, David C. Dale, Giao Hangoc, Geoffrey W. Henson
المصدر: Supportive Cancer Therapy. 1:165-172
مصطلحات موضوعية: Pharmacology, Cancer Research, Myeloid, business.industry, Monocyte, CD34, CXCR4, Subcutaneous injection, Haematopoiesis, medicine.anatomical_structure, Oncology, White blood cell, Immunology, Medicine, Leukocytosis, medicine.symptom, business
-
4
المؤلفون: Patrick Matthys, Dominique Schols, Sigrid Hatse, Erik De Clercq, Kurt Vermeire, Geoffrey W. Henson, Anja Wuyts, Gary Bridger, Alfons Billiau
المصدر: The Journal of Immunology. 167:4686-4692
مصطلحات موضوعية: Benzylamines, Receptors, CXCR4, Chemokine, Interferon type II, Immunology, Macrophage-1 Antigen, Arthritis, Inflammation, Cyclams, Autoantigens, Autoimmune Diseases, Interferon-gamma, Mice, Chemokine receptor, Heterocyclic Compounds, medicine, Animals, Immunology and Allergy, Hypersensitivity, Delayed, Stromal cell-derived factor 1, Collagen Type II, Mice, Knockout, CXCR4 antagonist, biology, Extremities, medicine.disease, Arthritis, Experimental, Chemokine CXCL12, Mice, Inbred DBA, Macrophage-1 antigen, biology.protein, medicine.symptom, Chemokines, CXC, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca554d38e8fb24d0b26a09fe0b40b30
https://doi.org/10.4049/jimmunol.167.8.4686 -
5
المؤلفون: Charles Flexner, Craig W. Hendrix, Gary Bridger, Ella Redpath, Edward J. Fuchs, Geoffrey W. Henson, Ronald Trevor Macfarland, Christen Giandomenico
المصدر: Antimicrobial Agents and Chemotherapy. 44:1667-1673
مصطلحات موضوعية: Benzylamines, Receptors, CXCR4, Anti-HIV Agents, Injections, Subcutaneous, Cmax, Pharmacology, Cyclams, Antiviral Agents, Mice, Subcutaneous injection, Pharmacokinetics, Heterocyclic Compounds, White blood cell, medicine, Animals, Humans, Pharmacology (medical), Dosing, Volume of distribution, business.industry, Liter, Infectious Diseases, medicine.anatomical_structure, Toxicity, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c38479d1796d4ee883240173ac1bbd9
https://doi.org/10.1128/aac.44.6.1667-1673.2000 -
6
المؤلفون: Myriam Witvrouw, Geoffrey W. Henson, Renaat Kinget, P. Augustijns, G. Van den Mooter, J. Van Gelder, Christophe Pannecouque, E. De Clercq, Pieter Annaert, M Shafiee, Gary Bridger, Lieve Naesens
المصدر: International Journal of Pharmaceutics. 186:127-136
مصطلحات موضوعية: Taurocholic Acid, Benzylamines, Octanols, Chemical Phenomena, Anti-HIV Agents, Organophosphonates, Pharmaceutical Science, Cyclams, Epithelium, Ion, chemistry.chemical_compound, Organophosphorus Compounds, Heterocyclic Compounds, Bromide, Animals, Humans, Solubility, Tenofovir, Chromatography, High Pressure Liquid, chemistry.chemical_classification, Aqueous solution, Chromatography, Chemistry, Physical, Chemistry, Adenine, Aqueous two-phase system, Bioavailability, Rabbits, Caco-2 Cells, Counterion, Absorption (chemistry), Nuclear chemistry
-
7
المؤلفون: Karen De Vreese, Myriam Witvrouw, Anne-Mieke Vandamme, Erik De Clercq, Jean-Claude Schmit, Gary Bridger, Jozef Anné, JoséA. Esté, Jan Desmyter, Geoffrey W. Henson
المصدر: Antiviral Research. 29:297-307
مصطلحات موضوعية: Benzylamines, Polymers, Drug resistance, Biology, Cyclams, Antiviral Agents, Virus, Microbiology, Heterocyclic Compounds, Virology, Tumor Cells, Cultured, medicine, Humans, Potency, Pharmacology, Drug Resistance, Microbial, Heparin, Polyelectrolytes, HIV Reverse Transcriptase, Reverse transcriptase, In vitro, Mechanism of action, Peripheral blood lymphocyte, HIV-1, Reverse Transcriptase Inhibitors, medicine.symptom, medicine.drug
-
8
المؤلفون: Geoffrey W. Henson, Sreenivasan Padmanabhan, H C Joao, Michael J. Abrams, De Vreese K, Gary Bridger, Stephen A. Martellucci, De Clercq E, Renato T. Skerlj, Myriam Witvrouw, Rudi Pauwels
المصدر: Journal of Medicinal Chemistry. 39:109-119
مصطلحات موضوعية: Cell Survival, Stereochemistry, Molecular Conformation, Virus Replication, Antiviral Agents, Chemical synthesis, Cell Line, Structure-Activity Relationship, chemistry.chemical_compound, Heterocyclic Compounds, Drug Discovery, Pyridine, Cyclam, Humans, Structure–activity relationship, Methylene, Aza Compounds, Molecular Structure, Hydrogen bond, Chemistry, Hydrogen Bonding, Hydrogen-Ion Concentration, Viral replication, HIV-2, HIV-1, Molecular Medicine, Spectrophotometry, Ultraviolet, Linker
-
9
المؤلفون: Jerry Muhammad, Babita Ganguly, Claire Bourdin, Stanley D. Chamberlain, Jeff T. Hutchins, Joseph M. Patti, C. Robin Walters, Andrea Brancale, Alexander A. Kolykhalov, Changalvala V. S. Ramamurty, Christopher McGuigan, Jin Wang, Aleksandr Obikhod, K. Dawn Bryant, Srinivas K. Battina, Elena Gorovits, Blair Bleiman, John Vernachio, Geoffrey W. Henson, Damound Hunley, C.Srivinas Rao
المصدر: Bioorganicmedicinal chemistry letters. 23(7)
مصطلحات موضوعية: Models, Molecular, Guanine, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Guanosine, Protide, Hepacivirus, Microbial Sensitivity Tests, Biochemistry, Antiviral Agents, Nucleobase, chemistry.chemical_compound, Drug Discovery, Nucleotide, Phosphoric Acids, Molecular Biology, chemistry.chemical_classification, Alanine, Molecular Structure, Organic Chemistry, Phosphoramidate, Esters, Prodrug, Amides, chemistry, Molecular Medicine, Nucleoside
-
10
المؤلفون: Hal E. Broxmeyer, Scott Cooper, David C. Dale, Geoffrey W. Henson, Elin Rodger, Gary Calandra, W. Conrad Liles, Gary Bridger, Kai Hübel, Brent L. Wood, Giao Hangoc
المصدر: Blood. 102:2728-2730
مصطلحات موضوعية: Adult, Male, Benzylamines, Receptors, CXCR4, Time Factors, Stromal cell, Anti-HIV Agents, medicine.medical_treatment, Immunology, CD34, Antigens, CD34, Hematopoietic stem cell transplantation, Pharmacology, Biology, Cyclams, Biochemistry, CXCR4, Heterocyclic Compounds, Granulocyte Colony-Stimulating Factor, medicine, Humans, Progenitor cell, Dose-Response Relationship, Drug, Plerixafor, Cell Biology, Hematology, Hematopoietic Stem Cells, Haematopoiesis, Female, Stem cell, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f22385b35c27272a6f3b24fabb66d472
https://doi.org/10.1182/blood-2003-02-0663