المؤلفون: Guanglin Luo, Ling Chen, Walter A. Kostich, Brian Hamman, Jason Allen, Amy Easton, Clotilde Bourin, Michael Gulianello, Jonathan Lippy, Susheel Nara, Sreenivasulu Naidu Pattipati, Kumaran Dandapani, Manoj Dokania, Pradeep Vattikundala, Vivek Sharma, Saravanan Elavazhagan, Manoj Kumar Verma, Manish Lal Das, Santosh Wagh, Anand Balakrishnan, Benjamin M. Johnson, Kenneth S. Santone, George Thalody, Rex Denton, Hariharan Saminathan, Vinay K. Holenarsipur, Anoop Kumar, Abhijith Rao, Siva Prasad Putlur, Sarat Kumar Sarvasiddhi, Ganesh Shankar, Justin V. Louis, Manjunath Ramarao, Charles M. Conway, Yu-Wen Li, Rick Pieschl, Yuan Tian, Yang Hong, Linda Bristow, Charles F. Albright, Joanne J. Bronson, John E. Macor, Carolyn D. Dzierba

المصدر: Journal of Medicinal Chemistry. 65:4534-4564

مصطلحات موضوعية: Mice, Structure-Activity Relationship, Spinal Cord, Anesthetics, General, Drug Discovery, Animals, Neuralgia, Molecular Medicine, Protein Kinase Inhibitors, Ethers, Rats

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbf11be6e3846cab6b37f029b5b93a8d
https://doi.org/10.1021/acs.jmedchem.1c02132

المؤلفون: Guanglin Luo, Ling Chen, Walter A. Kostich, Brian Hamman, Jason Allen, Amy Easton, Clotilde Bourin, Michael Gulianello, Jonathan Lippy, Susheel Nara, Tarun Kumar Maishal, Kamalraj Thiyagarajan, Prasadrao Jalagam, Sreenivasulu Naidu Pattipati, Kumaran Dandapani, Manoj Dokania, Pradeep Vattikundala, Vivek Sharma, Saravanan Elavazhagan, Manoj Kumar Verma, Manish Lal Das, Santosh Wagh, Anand Balakrishnan, Benjamin M. Johnson, Kenneth S. Santone, George Thalody, Rex Denton, Hariharan Saminathan, Vinay K. Holenarsipur, Anoop Kumar, Abhijith Rao, Siva Prasad Putlur, Sarat Kumar Sarvasiddhi, Ganesh Shankar, Justin V. Louis, Manjunath Ramarao, Charles M. Conway, Yu-Wen Li, Rick Pieschl, Yuan Tian, Yang Hong, Jonathan Ditta, Arvind Mathur, Jianqing Li, Daniel Smith, Joseph Pawluczyk, Dawn Sun, Shiuhang Yip, Dauh-Rurng Wu, Muthalagu Vetrichelvan, Anuradha Gupta, Alan Wilson, Suma Gopinathan, Suman Wason, Linda Bristow, Charles F. Albright, Joanne J. Bronson, John E. Macor, Carolyn D. Dzierba

المصدر: Journal of Medicinal Chemistry. 65:4457-4480

مصطلحات موضوعية: Drug Discovery, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::38224dcaf3d9ea2fabc4ac6df4a42a84
https://doi.org/10.1021/acs.jmedchem.1c02131

المؤلفون: Guanglin, Luo, Ling, Chen, Walter A, Kostich, Brian, Hamman, Jason, Allen, Amy, Easton, Clotilde, Bourin, Michael, Gulianello, Jonathan, Lippy, Susheel, Nara, Tarun Kumar, Maishal, Kamalraj, Thiyagarajan, Prasadrao, Jalagam, Sreenivasulu Naidu, Pattipati, Kumaran, Dandapani, Manoj, Dokania, Pradeep, Vattikundala, Vivek, Sharma, Saravanan, Elavazhagan, Manoj Kumar, Verma, Manish Lal, Das, Santosh, Wagh, Anand, Balakrishnan, Benjamin M, Johnson, Kenneth S, Santone, George, Thalody, Rex, Denton, Hariharan, Saminathan, Vinay K, Holenarsipur, Anoop, Kumar, Abhijith, Rao, Siva Prasad, Putlur, Sarat Kumar, Sarvasiddhi, Ganesh, Shankar, Justin V, Louis, Manjunath, Ramarao, Charles M, Conway, Yu-Wen, Li, Rick, Pieschl, Yuan, Tian, Yang, Hong, Jonathan, Ditta, Arvind, Mathur, Jianqing, Li, Daniel, Smith, Joseph, Pawluczyk, Dawn, Sun, Shiuhang, Yip, Dauh-Rurng, Wu, Muthalagu, Vetrichelvan, Anuradha, Gupta, Alan, Wilson, Suma, Gopinathan, Suman, Wason, Linda, Bristow, Charles F, Albright, Joanne J, Bronson, John E, Macor, Carolyn D, Dzierba

المصدر: Journal of medicinal chemistry. 65(6)

مصطلحات موضوعية: Mice, Spinal Cord, Animals, Brain, Neuralgia, Amines, Protein Kinase Inhibitors, Rats

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::1e41976413f9c4afd18a0630ac9bd2a0
https://pubmed.ncbi.nlm.nih.gov/35257579

المؤلفون: Sokhom S. Pin, Deborah A. Cook, John E. Macor, Laura J. Signor, Carl Davis, Valerie J. Whiterock, Gene M. Dubowchik, Richard Schartman, Ping Chen, Chaturvedula Prasad, Kimberly A. Widmann, George Thalody, Walter Kostich, Robert Macci, John J. Herbst, Stephen E. Mercer, Charles M. Conway, Cen Xu

المصدر: Bioorganicmedicinal chemistry letters. 31

مصطلحات موضوعية: Indazoles, Clinical Biochemistry, Pharmaceutical Science, Peptide, Calcitonin gene-related peptide, Pharmacology, 01 natural sciences, Biochemistry, Structure-Activity Relationship, In vivo, Calcitonin Gene-Related Peptide Receptor Antagonists, Drug Discovery, Humans, Receptor, Molecular Biology, chemistry.chemical_classification, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Organic Chemistry, Antagonist, Azepines, 0104 chemical sciences, Bioavailability, 010404 medicinal & biomolecular chemistry, Calcitonin, Molecular Medicine, Nasal administration, Receptors, Calcitonin Gene-Related Peptide

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f1b018775ed0613c97b43faeac8e918
https://pubmed.ncbi.nlm.nih.gov/33096162

المؤلفون: Kevin Fitzgerald, Svetlana Tertyshnikova, Lisa Moore, Lynn Bjerke, Ben Burley, Jian Cao, Pamela Carroll, Robert Choy, Steve Doberstein, Yves Dubaquie, Yvonne Franke, Jenny Kopczynski, Hendrik Korswagen, Stanley R Krystek, Nicholas J Lodge, Ronald Plasterk, John Starrett, Terry Stouch, George Thalody, Honey Wayne, Alexander van der Linden, Yongmei Zhang, Stephen G Walker, Mark Cockett, Judi Wardwell-Swanson, Petra Ross-Macdonald, Rachel M Kindt

المصدر: PLoS Genetics, Vol 2, Iss 4, p e57 (2006)

مصطلحات موضوعية: Genetics, QH426-470

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC1440875?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

URL الوصول: https://doaj.org/article/1932641b9cd346b58d4f8941da49cf1f

المؤلفون: George Thalody, Paul Levesque, Jae Kwagh, Hong Shi, Jingsong Fan, Geoff Lewen, Elisabeth Burnett, Shen-Jue Chen

المصدر: Toxicology in vitro : an international journal published in association with BIBRA. 55

مصطلحات موضوعية: 0301 basic medicine, Physostigmine, Drug Evaluation, Preclinical, Convulsants, Evoked field, Hippocampal formation, Toxicology, Hippocampus, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Seizures, medicine, Animals, Electrodes, Cells, Cultured, Neurons, General Medicine, Bicuculline, 030104 developmental biology, medicine.anatomical_structure, chemistry, 030220 oncology & carcinogenesis, Gabazine, Neuron, Neuroscience, Ex vivo, Picrotoxin, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52073f132ed41dfcd98aa116ce89c6a8
https://pubmed.ncbi.nlm.nih.gov/30528373

المؤلفون: John E. Macor, Chaturvedula Prasad, Rex Denton, Gene M. Dubowchik, Paul Moench, Valerie J. Whiterock, Charlie M. Conway, Cen Xu, Neil Mathias, Glenn H. Cantor, Robert Macci, Richard Schartman, Laura J. Signor, Stephen E. Mercer, George Thalody, Carl D. Davis, Deborah Keavy, Sokhom S. Pin

المصدر: Bioorganic & Medicinal Chemistry Letters. 23:3157-3161

مصطلحات موضوعية: Indazoles, medicine.drug_class, Migraine Disorders, Clinical Biochemistry, Drug Evaluation, Preclinical, Pharmaceutical Science, Peptide, Carboxamide, Respiratory Mucosa, Quinolones, Calcitonin gene-related peptide, Pharmacology, Biochemistry, chemistry.chemical_compound, Calcitonin Gene-Related Peptide Receptor Antagonists, Drug Discovery, medicine, Animals, Humans, Receptor, Molecular Biology, Administration, Intranasal, chemistry.chemical_classification, Organic Chemistry, Antagonist, Callithrix, Amides, Coronary Vessels, Rats, chemistry, Calcitonin, Face, Molecular Medicine, Nasal administration, Rabbits, Piperidine, Caco-2 Cells, Receptors, Calcitonin Gene-Related Peptide

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78ac514e0ff9910e3b128930ebdf5765
https://doi.org/10.1016/j.bmcl.2013.04.012

المؤلفون: George Thalody, Paul Moench, Valerie J. Whiterock, Deborah A. Cook, Charles M. Conway, Xiang-Jun Jiang, Laura J. Signor, Neil Mathias, Richard Schartman, Carl D. Davis, Cen Xu, Robert Macci, Xiaojun Han, George O. Tora, Sokhom S. Pin, John E. Macor, Gene M. Dubowchik, Andrew P. Degnan, Rita L. Civiello

المصدر: Bioorganic & Medicinal Chemistry Letters. 23:1870-1873

مصطلحات موضوعية: Indazoles, Clinical Biochemistry, Biological Availability, Pharmaceutical Science, Calcitonin gene-related peptide, Pharmacology, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Calcitonin Gene-Related Peptide Receptor Antagonists, Drug Discovery, Animals, Potency, Amino Acids, Tyrosine, Molecular Biology, Administration, Intranasal, Quinazolinones, chemistry.chemical_classification, Benzoxazoles, Indazole, Chemistry, Organic Chemistry, Bioavailability, Amino acid, Molecular Medicine, Racemic mixture, Nasal administration, Rabbits, Half-Life, Protein Binding, Receptors, Calcitonin Gene-Related Peptide

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9efad766cca18838d811178ca1ce78b8
https://doi.org/10.1016/j.bmcl.2013.01.011

المؤلفون: Carl D. Davis, Laura J. Signor, Chaturvedula Prasad, George Thalody, Richard Schartman, Gene M. Dubowchik, Rita L. Civiello, John E. Macor, Charles M. Conway, Shelly X. Ren, Robert Macci, Xiaojun Han, Deborah A. Cook, Kimberly A. Widmann, Cen Xu, Sokhom S. Pin

المصدر: Bioorganic & Medicinal Chemistry Letters. 22:4723-4727

مصطلحات موضوعية: Clinical Biochemistry, Pharmaceutical Science, In Vitro Techniques, Calcitonin gene-related peptide, Pharmacology, Biochemistry, Structure-Activity Relationship, Calcitonin Gene-Related Peptide Receptor Antagonists, Drug Discovery, Animals, Humans, Structure–activity relationship, Tyrosine, Molecular Biology, Alanine, chemistry.chemical_classification, Molecular Structure, CYP3A4, Chemistry, Organic Chemistry, Antagonist, Callithrix, Coronary Vessels, Amino acid, Cytochrome P-450 CYP3A Inhibitors, Molecular Medicine, Ex vivo

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc3bbed405bf048163d0f84953dedba
https://doi.org/10.1016/j.bmcl.2012.05.074

المؤلفون: Neil Mathias, Sokhom S. Pin, Xiaojun Han, Paul Moench, John E. Macor, Richard Schartman, Charles M. Conway, Chaturvedula Prasad, Rex Denton, Kimberly A. Widmann, Laura J. Signor, Gene M. Dubowchik, Deborah A. Cook, Andrew P. Degnan, George Thalody, Robert Macci, Carl D. Davis, Shelly X. Ren, Cen Xu

المصدر: Journal of Medicinal Chemistry. 51:4858-4861

مصطلحات موضوعية: Bicyclic molecule, medicine.drug_class, Stereochemistry, Chemistry, Carboxamide, Biological activity, Calcitonin gene-related peptide, Chemical synthesis, chemistry.chemical_compound, In vivo, Drug Discovery, medicine, Molecular Medicine, Piperidine, Ex vivo

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fa440795b5aa2edcd0d1f4a3cb63ab67
https://doi.org/10.1021/jm800546t