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1
المؤلفون: Carrie Xu, George C. Morton, Vinayak Hosagrahara, Shung Wu, Denis E. Ryono, Jonathan Lippy, Narayanan Hariharan, Kenneth T. Locke, Xiang-Xang Ye, Wei Wang, Liqun Gu, Yi-Xin Li, Fucheng Qu, Peter T. W. Cheng, Sean S. Chen, Kevin O’Malley, Michael Cap, Robert Zahler, Tao Wang, Lori Kunselman, Charles Z. Ding, Cuixia Chu, Rebecca A. Smirk, Neil Flynn, Pratik Devasthale, Hao Zhang, Nathan Morgan, Atsu Apedo, Thomas Harrity, Lisa Zhang, Dennis Farrelly, Arthur M. Doweyko, Zhi Lai, Tim Herpin, Pathanjali Kadiyala
المصدر: Bioorganic & Medicinal Chemistry Letters. 25:1196-1205
مصطلحات موضوعية: Blood Glucose, Pyrrolidines, Stereochemistry, Clinical Biochemistry, Mice, Obese, Pharmaceutical Science, Peroxisome proliferator-activated receptor, Ligands, Biochemistry, Pyrrolidine, Fasting glucose, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Animals, Hypoglycemic Agents, PPAR alpha, Molecular Biology, Triglycerides, Biological evaluation, chemistry.chemical_classification, Triglyceride, Organic Chemistry, Stereoisomerism, PPAR gamma, Diabetes Mellitus, Type 2, chemistry, Drug Design, Molecular Medicine, Female
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2
المؤلفون: Thomas J. Connors, Jie Qian, Zeck Huang, Joanne R. Mathiasen, Edward R. Bacon, Thelma S. Angeles, Mark J. Huffman, Emir Duzic, Joseph M. Salvino, Beth Ann McKenna, Hervé Schaffhauser, Robert J. McHugh, Lily D. Lu, George C. Morton, Beverly P. Holskin, Karla Kopec, Amy DiCamillo, Gerard C. Rosse, Chrysanthe Spais, Rabindranath Tripathy, Lisa D. Aimone
المصدر: Bioorganic & Medicinal Chemistry Letters. 22:1421-1426
مصطلحات موضوعية: Stereochemistry, Chemistry, Organic Chemistry, Clinical Biochemistry, Antagonist, Pharmaceutical Science, Stereoisomerism, Biochemistry, Sulfone, chemistry.chemical_compound, In vivo, Drug Discovery, 5-HT6 receptor, Molecular Medicine, Pharmacophore, Receptor, Molecular Biology, 5-HT receptor
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3
المؤلفون: Beverly P. Holskin, Karla Kopec, Joanne R. Mathiasen, Amy DiCamillo, Babu G. Sundar, Thomas J. Connors, Emir Duzic, Edward R. Bacon, Gerard C. Rosse, Chrysanthe Spais, Thomas R. Bailey, Beth Ann McKenna, Rebecca A. Brown, Jie Qian, Derek Dunn, Mark J. Huffman, Joseph M. Salvino, Huang Zeqi, Lisa D. Aimone, Hervé Schaffhauser, Deborah Galinis, Thelma S. Angeles, Lily D. Lu, George C. Morton
المصدر: Bioorganic & Medicinal Chemistry Letters. 22:120-123
مصطلحات موضوعية: biology, Organic Chemistry, Clinical Biochemistry, hERG, Pharmaceutical Science, Pharmacology, Biochemistry, Social recognition, chemistry.chemical_compound, chemistry, Drug Discovery, biology.protein, 5-HT6 receptor, Molecular Medicine, Structure–activity relationship, Serotonin Antagonists, Penetrant (biochemical), Receptor, Molecular Biology, 5-HT receptor
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4
المؤلفون: Kenneth E. Carlson, Stephen G. Walker, Barry Koplowitz, Kathleen M. Gillooly, John W. Haycock, Kim W. McIntyre, Ximao Wu, Stephen Roberts, Guixue Yu, John E. Macor, George C. Morton, Huji Tuerdi, Yifan Yang, Timothy F. Herpin, R. Michael Lawrence, Liya Kang, Judy Wardwell-Swanson, Ashish Khanna
المصدر: Journal of Leukocyte Biology. 80:897-904
مصطلحات موضوعية: Lipopolysaccharides, Male, Agonist, Time Factors, medicine.drug_class, medicine.medical_treatment, Immunology, Biology, Pharmacology, Cell Line, Mice, Structure-Activity Relationship, Cell Movement, In vivo, Leukocytes, medicine, Animals, Humans, Immunology and Allergy, Receptor, Lung, G protein-coupled receptor, Inflammation, Mice, Inbred BALB C, Dose-Response Relationship, Drug, Imidazoles, Cell Biology, Mice, Inbred C57BL, Molecular Weight, Cytokine, Cytokines, Female, Tumor necrosis factor alpha, Melanocortin, Receptor, Melanocortin, Type 1, Melanocortin 1 receptor
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5
المؤلفون: Kenneth E. Carlson, John S. Tokarski, George C. Morton, R. Michael Lawrence, Guixue Yu, Huji Tuerdi, John E. Macor, Timothy F. Herpin, Ximao Wu, Liya Kang, Ashish Khanna
المصدر: Journal of Medicinal Chemistry. 46:1123-1126
مصطلحات موضوعية: Lipopolysaccharides, Agonist, medicine.medical_specialty, medicine.drug_class, medicine.medical_treatment, Inflammation, Pharmacology, Anti-inflammatory, Mice, Structure-Activity Relationship, Internal medicine, Drug Discovery, Tumor Cells, Cultured, medicine, Enzyme-linked receptor, Animals, Combinatorial Chemistry Techniques, Humans, Selective receptor modulator, Receptor, Mice, Inbred BALB C, Tumor Necrosis Factor-alpha, Chemistry, Receptors, Melanocortin, Anti-Inflammatory Agents, Non-Steroidal, Cytokine, Endocrinology, Receptors, Corticotropin, Acute Disease, Tyrosine, Molecular Medicine, medicine.symptom, Melanocortin 1 receptor
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6
المؤلفون: Rabindranath, Tripathy, Robert J, McHugh, Edward R, Bacon, Joseph M, Salvino, George C, Morton, Lisa D, Aimone, Zeck, Huang, Joanne R, Mathiasen, Amy, DiCamillo, Mark J, Huffman, Beth A, McKenna, Karla, Kopec, Lily D, Lu, Jie, Qian, Thelma S, Angeles, Thomas, Connors, Chrysanthe, Spais, Beverly, Holskin, Emir, Duzic, Hervé, Schaffhauser, Gerard C, Rossé
المصدر: Bioorganicmedicinal chemistry letters. 22(3)
مصطلحات موضوعية: Molecular Structure, Brain, Stereoisomerism, Rats, Inhibitory Concentration 50, Mice, Dogs, Receptors, Serotonin, Microsomes, Liver, Animals, Humans, Serotonin Antagonists, Sulfones, Heterocyclic Compounds, 3-Ring
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7
المؤلفون: Babu G, Sundar, Thomas R, Bailey, Derek D, Dunn, Edward R, Bacon, Joseph M, Salvino, George C, Morton, Lisa D, Aimone, Huang, Zeqi, Joanne R, Mathiasen, Amy, Dicamillo, Mark J, Huffman, Beth A, McKenna, Karla, Kopec, Lily D, Lu, Rebecca, Brown, Jie, Qian, Thelma, Angeles, Thomas, Connors, Chrysanthe, Spais, Beverly, Holskin, Deborah, Galinis, Emir, Duzic, Herve, Schaffhauser, Gerard C, Rosse
المصدر: Bioorganicmedicinal chemistry letters. 22(1)
مصطلحات موضوعية: ERG1 Potassium Channel, Brain, Ether-A-Go-Go Potassium Channels, Rats, Inhibitory Concentration 50, Kinetics, Structure-Activity Relationship, Memory, Short-Term, Models, Chemical, Piperidines, Receptors, Serotonin, Schizophrenia, Animals, Humans, Serotonin Antagonists, Benzofurans
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8
المؤلفون: R. Michael Lawrence, George C. Morton, Mark E. Salvati, Jonathan O’Connell, Ramakrishna Seethala, Arthur V. Miller, Tara L. Peterson, Cooper Christopher B, Carolyn A. Weigelt, Yalei Liu, Tammy C. Wang, Lalgudi S. Harikrishnan, Timothy F. Herpin, Kingsley K. Appiah, David S. Taylor, Xiaohong Yin, Muthoni G. Kamau, Jennifer X. Qiao, Leonard P. Adam, Alice Ye A. Chen, David S. Nirschl
المصدر: Bioorganicmedicinal chemistry letters. 18(8)
مصطلحات موضوعية: Models, Molecular, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Carboxamide, Biochemistry, Chemical synthesis, chemistry.chemical_compound, Structure-Activity Relationship, Drug Discovery, Cholesterylester transfer protein, medicine, Humans, Molecular Biology, CETP inhibitor, Benzoxazoles, biology, Molecular Structure, Chemistry, Organic Chemistry, Benzoxazole, Fluorescence, Coronary heart disease, Cholesterol Ester Transfer Proteins, Pattern synthesis, biology.protein, Molecular Medicine, lipids (amino acids, peptides, and proteins)
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9
المؤلفون: Timothy F, Herpin, George C, Morton
المصدر: Methods in enzymology. 369
مصطلحات موضوعية: Heterocyclic Compounds, Combinatorial Chemistry Techniques