المؤلفون: Seun Akindehin, Arkadiusz Liskiewicz, Daniela Liskiewicz, Miriam Bernecker, Cristina Garcia-Caceres, Daniel J. Drucker, Brian Finan, Gerald Grandl, Robert Gutgesell, Susanna M. Hofmann, Ahmed Khalil, Xue Liu, Perla Cota, Mostafa Bakhti, Oliver Czarnecki, Aimée Bastidas-Ponce, Heiko Lickert, Lingru Kang, Gandhari Maity, Aaron Novikoff, Sebastian Parlee, Ekta Pathak, Sonja C. Schriever, Michael Sterr, Siegfried Ussar, Qian Zhang, Richard DiMarchi, Matthias H. Tschöp, Paul T. Pfluger, Jonathan D. Douros, Timo D. Müller

المصدر: Molecular Metabolism, Vol 83, Iss , Pp 101915- (2024)

مصطلحات موضوعية: Obesity, Type 2 diabetes, GIP, GLP-1, GIPR:GLP-1R co-agonism, Internal medicine, RC31-1245

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2212877824000462; https://doaj.org/toc/2212-8778

URL الوصول: https://doaj.org/article/4df457ac59ce49e8af09680efdd590e2

المؤلفون: Aaron Novikoff, Shannon L. O'Brien, Miriam Bernecker, Gerald Grandl, Maximilian Kleinert, Patrick J. Knerr, Kerstin Stemmer, Martin Klingenspor, Anja Zeigerer, Richard DiMarchi, Matthias H. Tschöp, Brian Finan, Davide Calebiro, Timo D. Müller

المصدر: Molecular Metabolism, Vol 49, Iss , Pp 101181- (2021)

مصطلحات موضوعية: GLP-1R, GIPR, Biased agonism, Receptor Internalization, Receptor Trafficking, Dual-agonists, Internal medicine, RC31-1245

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2212877821000211; https://doaj.org/toc/2212-8778

URL الوصول: https://doaj.org/article/3747ffadfcfc4ababd52d92c0564e71b

المؤلفون: Christoffer Clemmensen, Sigrid Jall, Maximilian Kleinert, Carmelo Quarta, Tim Gruber, Josefine Reber, Stephan Sachs, Katrin Fischer, Annette Feuchtinger, Angelos Karlas, Stephanie E. Simonds, Gerald Grandl, Daniela Loher, Eva Sanchez-Quant, Susanne Keipert, Martin Jastroch, Susanna M. Hofmann, Emmani B. M. Nascimento, Patrick Schrauwen, Vasilis Ntziachristos, Michael A. Cowley, Brian Finan, Timo D. Müller, Matthias H. Tschöp

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/daba42e8bc934c15ab731e4faf7ff42c

المؤلفون: Gerald Grandl, Sebastian Müller, Hansjörg Moest, Caroline Moser, Bernd Wollscheid, Christian Wolfrum

المصدر: Molecular Metabolism, Vol 5, Iss 10, Pp 937-947 (2016)

مصطلحات موضوعية: Internal medicine, RC31-1245

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2212877816301016; https://doaj.org/toc/2212-8778

URL الوصول: https://doaj.org/article/8a97ace8af1e47c4a71b5ca8ed9bc4a6

المؤلفون: Christoffer Clemmensen, Sigrid Jall, Maximilian Kleinert, Carmelo Quarta, Tim Gruber, Josefine Reber, Stephan Sachs, Katrin Fischer, Annette Feuchtinger, Angelos Karlas, Stephanie E. Simonds, Gerald Grandl, Daniela Loher, Eva Sanchez-Quant, Susanne Keipert, Martin Jastroch, Susanna M. Hofmann, Emmani B. M. Nascimento, Patrick Schrauwen, Vasilis Ntziachristos, Michael A. Cowley, Brian Finan, Timo D. Müller, Matthias H. Tschöp

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/ae33b6c3d2134fc19b2fa65e3a0a054d

المؤلفون: Nathalie Hennuyer, Diego Perez-Tilve, Felix Klingelhuber, Brian Finan, Cristina García-Cáceres, Daniel J. Drucker, Susanna M. Hofmann, Perla Cota, Fanny Lalloyer, Carmelo Quarta, Natalie Krahmer, Mostafa Bakhti, Stephan Herzig, Gustav Collden, Qian Zhang, Gandhari Maity, Gerald Grandl, Miguel A. Sánchez-Garrido, Richard D. Dimarchi, Bard Staels, Timo D. Müller, Aimée Bastidas-Ponce, Eric Baugé, Matthias Tschoep, Heiko Lickert, Konxhe Kulaj, Alexandra Harger, Kerstin Stemmer, Christoffer Clemmensen, Bin Yang, Aaron Novikoff

مصطلحات موضوعية: Agonist, chemistry.chemical_classification, endocrine system, medicine.medical_specialty, Tesaglitazar, business.industry, medicine.drug_class, digestive, oral, and skin physiology, Peroxisome proliferator-activated receptor, Carbohydrate metabolism, medicine.disease, Obesity, chemistry.chemical_compound, Endocrinology, chemistry, Internal medicine, Medicine, business, hormones, hormone substitutes, and hormone antagonists

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::abbe6c86c35688a6dbf16211c6cfbeea
https://doi.org/10.21203/rs.3.rs-1081959/v1

المؤلفون: Carmelo Quarta, Kerstin Stemmer, Aaron Novikoff, Bin Yang, Felix Klingelhuber, Alex Harger, Mostafa Bakhti, Aimee Bastidas-Ponce, Eric Baugé, Jonathan E. Campbell, Megan Capozzi, Christoffer Clemmensen, Gustav Collden, Perla Cota, Jon Douros, Daniel J. Drucker, Barent DuBois, Annette Feuchtinger, Cristina Garcia-Caceres, Gerald Grandl, Nathalie Hennuyer, Stephan Herzig, Susanna M. Hofmann, Patrick J. Knerr, Konxhe Kulaj, Fanny Lalloyer, Heiko Lickert, Arek Liskiewicz, Daniela Liskiewicz, Gandhari Maity, Diego Perez-Tilve, Sneha Prakash, Miguel A. Sanchez-Garrido, Qian Zhang, Bart Staels, Natalie Krahmer, Richard D. DiMarchi, Matthias H. Tschöp, Brian Finan, Timo D. Müller

المصدر: Quarta, C, Stemmer, K, Novikoff, A, Yang, B, Klingelhuber, F, Harger, A, Bakhti, M, Bastidas-Ponce, A, Baugé, E, Campbell, J E, Capozzi, M, Clemmensen, C, Collden, G, Cota, P, Douros, J, Drucker, D J, DuBois, B, Feuchtinger, A, Garcia-Caceres, C, Grandl, G, Hennuyer, N, Herzig, S, Hofmann, S M, Knerr, P J, Kulaj, K, Lalloyer, F, Lickert, H, Liskiewicz, A, Liskiewicz, D, Maity, G, Perez-Tilve, D, Prakash, S, Sanchez-Garrido, M A, Zhang, Q, Staels, B, Krahmer, N, DiMarchi, R D, Tschöp, M H, Finan, B & Müller, T D 2022, ' GLP-1-mediated delivery of tesaglitazar improves obesity and glucose metabolism in male mice ', Nature Metabolism, vol. 4, no. 8, pp. 1071-1083 . https://doi.org/10.1038/s42255-022-00617-6
Nature Metabolism
Nat. Metab. 4, 1071-1083 (2022)

مصطلحات موضوعية: Alkanesulfonates, Male, Phenylpropionates, Endocrinology, Diabetes and Metabolism, Body Weight, Cell Biology, Glucagon-Like Peptide-1 Receptor, Mice, Glucose, Diabetes Mellitus, Type 2, Glucagon-Like Peptide 1, Physiology (medical), Internal Medicine, Animals, PPAR alpha, ddc:610, Obesity

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d8cb25c43d6de39a162496e77b8cbe0
https://pubmed.ncbi.nlm.nih.gov/35995998

المؤلفون: Timo D. Müller, Martin Klingenspor, Matthias H. Tschöp, Richard D. DiMarchi, Brian Finan, Maximilian Kleinert, Patrick J. Knerr, Anja Zeigerer, Miriam Bernecker, Kerstin Stemmer, Davide Calebiro, Shannon L. O'Brien, Aaron Novikoff, Gerald Grandl

المصدر: Molecular Metabolism, Vol 49, Iss, Pp 101181-(2021)
Molecular Metabolism

مصطلحات موضوعية: 0301 basic medicine, endocrine system, Gs alpha subunit, G protein, Endosome, media_common.quotation_subject, 030209 endocrinology & metabolism, Gastric Inhibitory Polypeptide, Ligands, Biased agonism, Receptors, Gastrointestinal Hormone, 03 medical and health sciences, 0302 clinical medicine, Dual-agonists, Glucagon-Like Peptide 1, Functional selectivity, Humans, ddc:610, Internalization, Receptor, Molecular Biology, Internal medicine, GIPR, media_common, GLP-1R, Chemistry, Semaglutide, Cell Biology, RC31-1245, Cell biology, HEK293 Cells, 030104 developmental biology, Receptor Internalization, Original Article, Receptor Trafficking, Peptides, Intracellular, hormones, hormone substitutes, and hormone antagonists, Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d435d268095d850d877448a2ff053db0
http://www.sciencedirect.com/science/article/pii/S2212877821000211

المؤلفون: Mostafa Bakhti, Diego Perez-Tilve, Konxhe Kulaj, Beata Legutko, Susanna M. Hofmann, Dominik Lutter, Kerstin Stemmer, Gerd Luippold, Stephanie A. Mowery, Marta Tarquis Medina, Stephan Herzig, Gustav Collden, Robert Augustin, Timo D. Müller, Cristina Garcia Caceres, Christian Wolfrum, Richard D. DiMarchi, Susanne Keipert, Xue Liu, Qian Zhang, Alexandra Harger, Cassie Holleman, Brian Finan, Maximilian Kleinert, Emilija Malogajski, Ciro Salinno, Matthias H. Tschöp, Andreas Blutke, Martin Jastroch, Gerald Grandl, Annette Feuchtinger, Patrick J. Knerr, Daniel J. Drucker, Laura Sehrer, Challa Tenagne Delessa, Heiko Lickert

المصدر: Cell Metabolism, 33 (4)
Cell Metabolism
Cell Metab. 33, 833-844.e5 (2021)

مصطلحات موضوعية: 0301 basic medicine, Central Nervous System, Male, Food intake, food intake, Physiology, Eating, Mice, 0302 clinical medicine, Glucagon-Like Peptide 1, Premovement neuronal activity, 2. Zero hunger, GIP, GIPR CNS KO, incretin, 3. Good health, Peripheral, ddc, Cns, Gip, Gipr Cns Ko, Body Weight, Diet-induced Obesity, Food Intake, Glucose Metabolism, Incretin, Type 2 Diabetes, Metabolic effects, Glucose-dependent insulinotropic polypeptide, type 2 diabetes, CNS, Proto-Oncogene Proteins c-fos, hormones, hormone substitutes, and hormone antagonists, Signal Transduction, medicine.medical_specialty, diet-induced obesity, glucose metabolism, Hypothalamus, Mice, Transgenic, Gastric Inhibitory Polypeptide, Biology, Carbohydrate metabolism, Body weight, Diet, High-Fat, Article, Receptors, Gastrointestinal Hormone, 03 medical and health sciences, body weight, Internal medicine, medicine, Animals, Humans, ddc:610, Obesity, Molecular Biology, Cell Biology, medicine.disease, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, 030217 neurology & neurosurgery

وصف الملف: application/application/pdf; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ad196864aba83940728afa229ef093f
https://hdl.handle.net/20.500.11850/478121

المؤلفون: Diego Perez-Tilve, Kerstin Stemmer, Christian Wolfrum, Xue Liu, Qian Zhang, Susanna M. Hofmann, Cassie Lynn Hollemann, Heiko Lickert, Brian Finan, Marta Tarquis Medina, Gustav Collden, Patrick J. Knerr, Emilija Malogajski, Matthias H. Tschöp, Mostafa Bakhti, Daniel J. Drucker, Laura Sehrer, Cristina Garcia Caceres, Ciro Salinno, Stephanie A. Mowery, Andreas Parzefall, Gerald Grandl, Annette Feuchtinger, Timo Dirk Müller, Challa Tenagne Delessa, Richard D. DiMarchi, Alexandra Harger, Maximilian Kleinert, Robert Augustin, Konxhe Kulaj, Beata Legutko, Gerd Luippold

المصدر: SSRN Electronic Journal.

مصطلحات موضوعية: endocrine system, medicine.medical_specialty, Food intake, Lateral hypothalamus, digestive, oral, and skin physiology, Wild type, Type 2 diabetes, Biology, Body weight, medicine.disease, Obesity, Endocrinology, Internal medicine, medicine, Glucose-dependent insulinotropic polypeptide, Premovement neuronal activity, hormones, hormone substitutes, and hormone antagonists

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f79aeb9542d6bf63e1a383daa8faa6b4
https://doi.org/10.2139/ssrn.3667144