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1دورية أكاديمية
المؤلفون: Jacquelyn A. Brown, Shannon L. Faley, Yajuan Shi, Kathleen M. Hillgren, Geri A. Sawada, Thomas K. Baker, John P. Wikswo, Ethan S. Lippmann
المصدر: Fluids and Barriers of the CNS, Vol 17, Iss 1, Pp 1-12 (2020)
مصطلحات موضوعية: Neurology. Diseases of the nervous system, RC346-429
وصف الملف: electronic resource
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المؤلفون: Thomas K. Baker, John P. Wikswo, Geri A. Sawada, Shannon Faley, Kathleen M. Hillgren, Ethan S. Lippmann, Yajuan Shi, Jacquelyn A. Brown
المصدر: Fluids and Barriers of the CNS, Vol 17, Iss 1, Pp 1-12 (2020)
Fluids and Barriers of the CNSمصطلحات موضوعية: 0301 basic medicine, Loperamide, Hydrocortisone, Induced Pluripotent Stem Cells, Models, Neurological, Central nervous system, Blood–brain barrier, lcsh:RC346-429, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Developmental Neuroscience, medicine, Humans, Cells, Cultured, Barrier function, lcsh:Neurology. Diseases of the nervous system, business.industry, Research, Endothelial Cells, General Medicine, Human brain, Coculture Techniques, Analgesics, Opioid, 030104 developmental biology, medicine.anatomical_structure, Neurology, Opioid, Blood-Brain Barrier, Astrocytes, Microvessels, Morphine, business, Oxycodone, Neuroscience, 030217 neurology & neurosurgery, medicine.drug
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المؤلفون: Anil Kolur, Yingying Guo, Geri A. Sawada, Andrew T. Hogan, Shelby Hullett, Kathleen M. Hillgren, Bridget L. Morse, Michael A. Mohutsky
المصدر: Drug Metabolism and Pharmacokinetics. 35:S92-S93
مصطلحات موضوعية: Pharmacology, business.industry, Pharmaceutical Science, Medicine, Hepatic clearance, Pharmacology (medical), business, Risk assessment
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المؤلفون: Thomas J. Raub, Timothy M. Jones, Geri A. Sawada, Elena Dolgikh, Stuart Morton, Prashant V. Desai, Ian A. Watson
المصدر: Journal of Chemical Information and Modeling. 56:2225-2233
مصطلحات موضوعية: 0301 basic medicine, Quantitative structure–activity relationship, biology, Correlation coefficient, Chemistry, General Chemical Engineering, General Chemistry, Library and Information Sciences, 030226 pharmacology & pharmacy, Regression, Computer Science Applications, Partition coefficient, Data set, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Test set, Statistics, biology.protein, Biological system, Kappa, P-glycoprotein
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المؤلفون: Young A Choi, Jason M. Grayson, Gregory A. Schamerhorn, Mark W. Kryman, Geri A. Sawada, Kellie S. Davies, Michelle K. Linder, Zachariah A. McIver, Benjamin N. Coe, Michael R. Detty, Jacqueline E. Hill
المصدر: Bioorganic & Medicinal Chemistry. 24:3918-3931
مصطلحات موضوعية: 0301 basic medicine, Light, Lymphoma, T-Lymphocytes, T cell, medicine.medical_treatment, Clinical Biochemistry, Population, Pharmaceutical Science, Biochemistry, Article, 03 medical and health sciences, Interleukin 21, 0302 clinical medicine, Photopheresis, Cell Line, Tumor, Organoselenium Compounds, Drug Discovery, Extracorporeal Photopheresis, medicine, Humans, Cytotoxic T cell, Photosensitizer, ATP Binding Cassette Transporter, Subfamily B, Member 1, education, Molecular Biology, education.field_of_study, Photosensitizing Agents, Rhodamines, Chemistry, Organic Chemistry, Mitochondria, 030104 developmental biology, medicine.anatomical_structure, Verapamil, 030220 oncology & carcinogenesis, Immunology, Cancer research, Molecular Medicine, CD8
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المؤلفون: Michael A. Mohutsky, Junliang Hao, Xin Zhou, Kenneth C. Cassidy, Loyd R. Hudson, Geri A. Sawada
المصدر: Pharmacology Research & Perspectives
مصطلحات موضوعية: Male, Metabolite, microbiome hydrolysis, Glucuronidation, Pharmacology, Urine, 030226 pharmacology & pharmacy, Excretion, 03 medical and health sciences, chemistry.chemical_compound, Feces, 0302 clinical medicine, Dogs, Glucuronides, Pharmacokinetics, Enterohepatic Circulation, P‐glycoprotein, Animals, General Pharmacology, Toxicology and Pharmaceutics, Canagliflozin, Enterohepatic circulation, Chemistry, Reabsorption, glucuronidation, Original Articles, Isoquinolines, Neurology, 030220 oncology & carcinogenesis, Original Article, Administration, Intravenous, Bile Ducts, Glucuronide, Drug metabolism, Half-Life
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المؤلفون: Jaclyn A. Barrett, Matthew R. Naylor, Maria-Jesus Blanco, R. Scott Lokey, Cameron R. Pye, Yongtong Lao, Isabel C. Gonzalez Valcarcel, Prashant V. Desai, Joshua Schwochert, Geri A. Sawada
المصدر: ACS Medicinal Chemistry Letters. 7:757-761
مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, Natural product, 010405 organic chemistry, Hydrogen bond, Stereochemistry, Organic Chemistry, Solvation, 01 natural sciences, Biochemistry, Cyclic peptide, 0104 chemical sciences, Polar surface area, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, chemistry, Permeability (electromagnetism), Drug Discovery, Epimer, Solubility
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المصدر: Molecular pharmaceutics. 15(8)
مصطلحات موضوعية: 0301 basic medicine, Quantitative structure–activity relationship, In silico, Chemistry, Pharmaceutical, Pharmaceutical Science, Computational biology, 030226 pharmacology & pharmacy, Small Molecule Libraries, 03 medical and health sciences, Structure-Activity Relationship, 0302 clinical medicine, Drug Discovery, Structure–activity relationship, Humans, Computer Simulation, Drug Interactions, Chemistry, Drug discovery, Liver-Specific Organic Anion Transporter 1, Transporter, Matthews correlation coefficient, In vitro, Solute carrier family, 030104 developmental biology, HEK293 Cells, Models, Chemical, Molecular Medicine, Biological Assay
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المؤلفون: Geri A. Sawada, Graham N. Wishart, Alfonso De Dios, Harlan E. Shannon, Brian A. Staton, Palaniappan Kulanthaivel, Thomas J. Raub, Lawrence M. Gelbert, Concepcion Sanchez-Martinez, Rose T. Ajamie
المصدر: Drug Metabolism and Disposition. 43:1360-1371
مصطلحات موضوعية: Male, Pyridines, Central nervous system, Aminopyridines, Pharmaceutical Science, Pharmacology, Palbociclib, Piperazines, Madin Darby Canine Kidney Cells, Mice, Dogs, Glioma, Antineoplastic Combined Chemotherapy Protocols, Temozolomide, medicine, Animals, Protein Kinase Inhibitors, biology, Brain Neoplasms, Kinase, business.industry, Area under the curve, Brain, Cyclin-Dependent Kinase 4, Cyclin-Dependent Kinase 6, medicine.disease, Xenograft Model Antitumor Assays, Rats, Dacarbazine, medicine.anatomical_structure, biology.protein, Benzimidazoles, Female, Cyclin-dependent kinase 6, Efflux, Glioblastoma, business, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc94e60e6774ce83490efe72b1e96090
https://doi.org/10.1124/dmd.114.062745 -
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المؤلفون: Michael R. Detty, Janet Morgan, Tymish Y. Ohulchanskyy, Michelle K. Linder, Geri A. Sawada, Kellie S. Davies, Jacqueline E. Hill
المصدر: Journal of Medicinal Chemistry
مصطلحات موضوعية: Stereochemistry, medicine.medical_treatment, Photodynamic therapy, Chemistry Techniques, Synthetic, Article, Madin Darby Canine Kidney Cells, Mice, chemistry.chemical_compound, Dogs, Cell Line, Tumor, Organoselenium Compounds, Toxicity Tests, Drug Discovery, medicine, Animals, Humans, ATP Binding Cassette Transporter, Subfamily B, Member 1, Thioamide, P-glycoprotein, chemistry.chemical_classification, Photosensitizing Agents, Singlet Oxygen, biology, Rhodamines, Singlet oxygen, digestive system diseases, In vitro, 3. Good health, Spectrometry, Fluorescence, Photochemotherapy, Verapamil, chemistry, Doxorubicin, Cell culture, Cancer cell, biology.protein, Biophysics, Molecular Medicine, Drug Screening Assays, Antitumor, Phototoxicity