-
1
المؤلفون: Terry, Podoll, Paul G, Pearson, Allard, Kaptein, Jerry, Evarts, Gerjan, de Bruin, Maaike, Emmelot-van Hoek, Anouk, de Jong, Bart, van Lith, Hao, Sun, Stephen, Byard, Adrian, Fretland, Niels, Hoogenboom, Tjeerd, Barf, J Greg, Slatter
المصدر: Journal of Pharmacology and Experimental Therapeutics. 384:173-186
مصطلحات موضوعية: Pharmacology, Molecular Medicine
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5b51ca94d968a8dbd551ff1f2f6f4a3
https://doi.org/10.1124/jpet.122.001116 -
2دورية أكاديمية
المؤلفون: Marianne Kraus, Juergen Bader, Paul P. Geurink, Emily S. Weyburne, Anne C. Mirabella, Tobias Silzle, Tamer B. Shabaneh, Wouter A. van der Linden, Gerjan de Bruin, Sarah R. Haile, Eva van Rooden, Christina Appenzeller, Nan Li, Alexei F. Kisselev, Herman Overkleeft, Christoph Driessen
المصدر: Haematologica, Vol 100, Iss 10 (2015)
مصطلحات موضوعية: Diseases of the blood and blood-forming organs, RC633-647.5
وصف الملف: electronic resource
-
3
المؤلفون: Bogdan I. Florea, Emily S. Weyburne, Bo-Tao Xin, Marissa Janssens, Wolfgang Heinemeyer, Eva M. Huber, Gerjan de Bruin, Michael Groll, Christoph Driessen, Gijsbert A. van der Marel, Alexei F. Kisselev, Christofer Espinal, Yimeng Du, Elmer Maurits, Herman S. Overkleeft
المصدر: Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, 62(3), 1626-1642
'Journal of Medicinal Chemistry ', vol: 62, pages: 1626-1642 (2019)مصطلحات موضوعية: Proteasome Endopeptidase Complex, Saccharomyces cerevisiae Proteins, Structural similarity, Protein subunit, Recombinant Fusion Proteins, Mutagenesis (molecular biology technique), Plasma protein binding, Saccharomyces cerevisiae, Crystallography, X-Ray, Protein Engineering, 01 natural sciences, Article, Small Molecule Libraries, 03 medical and health sciences, Mice, Peptide Library, Catalytic Domain, Cell Line, Tumor, Drug Discovery, Animals, Humans, Peptide library, 030304 developmental biology, 0303 health sciences, Chemistry, Stereoisomerism, Protein engineering, ddc, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Protein Subunits, Proteasome, Structural biology, Biochemistry, Drug Design, Mutation, Molecular Medicine, Oligopeptides, Proteasome Inhibitors, Protein Binding
وصف الملف: application/pdf
-
4
المؤلفون: Tjeerd Barf, Bart Van Lith, Todd Covey, Dennis Demont, Niels Hoogenboom, Bas van de Kar, Saskia Verkaik, Allard Kaptein, Maaike van Hoek, Gerjan de Bruin, Michael Gulrajani, Edwin de Zwart
المصدر: Bioorganicmedicinal chemistry letters. 30(14)
مصطلحات موضوعية: Models, Molecular, Clinical Biochemistry, Pharmaceutical Science, 01 natural sciences, Biochemistry, chemistry.chemical_compound, Structure-Activity Relationship, immune system diseases, In vivo, hemic and lymphatic diseases, Drug Discovery, Quinazoline, Agammaglobulinaemia Tyrosine Kinase, Bruton's tyrosine kinase, Humans, Molecular Biology, Protein Kinase Inhibitors, biology, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Btk inhibitors, Kinase, Organic Chemistry, Quinoline, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry, biology.protein, Cancer research, Quinolines, Molecular Medicine
-
5
المؤلفون: Bogdan I. Florea, Bo-Tao Xin, Christofer Espinal, Gijsbert A. van der Marel, Herman S. Overkleeft, Dmitri V. Filippov, Gerjan de Bruin
المصدر: ChemBioChem, 21(1-2), 248-255
مصطلحات موضوعية: Azides, Proteasome Endopeptidase Complex, 010402 general chemistry, 01 natural sciences, Biochemistry, Cell membrane, Catalytic Domain, Cell Line, Tumor, medicine, Humans, Molecular Biology, chemistry.chemical_classification, Molecular Structure, 010405 organic chemistry, Chemistry, Biomolecule, Organic Chemistry, Activity-based proteomics, In vitro, 0104 chemical sciences, Raji cell, medicine.anatomical_structure, Proteasome, Alkynes, Biotinylation, Molecular Medicine, Bioorthogonal chemistry, Proteasome Inhibitors
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2582e65d4c86b84a5c18d3e612dd62c
https://hdl.handle.net/1887/3199007 -
6
المؤلفون: Elmer Maurits, Herman S. Overkleeft, Marcus Groettrup, Michael Basler, Julia Koerner, Gerjan de Bruin
المصدر: British Journal of Pharmacology. 175:38-52
مصطلحات موضوعية: 0301 basic medicine, Pharmacology, Autoimmune disease, Chemistry, medicine.medical_treatment, Biological activity, medicine.disease_cause, medicine.disease, Autoimmunity, 03 medical and health sciences, Haematopoiesis, 030104 developmental biology, Cytokine, Proteasome, Immunology, Proteasome inhibitor, medicine, Cancer research, Cytokine secretion, medicine.drug
-
7
المؤلفون: Christoph Driessen, Eva J. van Rooden, Charlotte M J Wesseling, David Ward, Herman S. Overkleeft, Gerjan de Bruin, Constant A. A. van Boeckel, Bogdan I. Florea, Mario van der Stelt, Alexei F. Kisselev, Adrianus M. C. H. van den Nieuwendijk
المصدر: European Journal of Organic Chemistry. 2017:5921-5934
مصطلحات موضوعية: chemistry.chemical_classification, Oligopeptide, 010405 organic chemistry, Chemistry, Peptidomimetic, Stereochemistry, Organic Chemistry, Lysine, 010402 general chemistry, 01 natural sciences, 0104 chemical sciences, Amino acid, Proteasome, Proteasome inhibitor, medicine, Moiety, Physical and Theoretical Chemistry, Histidine, medicine.drug
-
8
المؤلفون: Bo-Tao Xin, Gerjan de Bruin, Herman S. Overkleeft, Bogdan I. Florea
المصدر: Journal of the American Chemical Society. 138:9874-9880
مصطلحات موضوعية: 0301 basic medicine, Cytoplasm, Proteasome Endopeptidase Complex, Protein subunit, 7. Clean energy, 01 natural sciences, Biochemistry, Protein Structure, Secondary, Catalysis, 03 medical and health sciences, Colloid and Surface Chemistry, Protein structure, Fluorescence Resonance Energy Transfer, Humans, Binding site, Fluorescent Dyes, Binding Sites, 010405 organic chemistry, Chemistry, Native Polyacrylamide Gel Electrophoresis, General Chemistry, Core Particle, 0104 chemical sciences, 030104 developmental biology, Förster resonance energy transfer, Proteasome, Composition (visual arts), Proteasome Inhibitors, HeLa Cells
-
9
المؤلفون: Gijsbert A. van der Marel, Bo-Tao Xin, Gerjan de Bruin, Bogdan I. Florea, Herman S. Overkleeft, Jan-Willem Plomp
المصدر: European Journal of Organic Chemistry. 2016:1132-1144
مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, Proteasome Inhibition, Ketone, 010405 organic chemistry, Peptidomimetic, Chemistry, Stereochemistry, Organic Chemistry, Peptide, Epoxy, Vinyl sulfone, 01 natural sciences, 0104 chemical sciences, 03 medical and health sciences, 030104 developmental biology, Proteasome, visual_art, visual_art.visual_art_medium, Moiety, Physical and Theoretical Chemistry
-
10
المؤلفون: Alexei F. Kisselev, Gijsbert A. van der Marel, Bogdan I. Florea, Mario van der Stelt, Bo-Tao Xin, Herman S. Overkleeft, Marianne Kraus, Christoph Driessen, Gerjan de Bruin
المصدر: Angewandte Chemie (International ed. in English)
مصطلحات موضوعية: 0301 basic medicine, Proteasome Endopeptidase Complex, Protein subunit, 01 natural sciences, Catalysis, anticancer agents, 03 medical and health sciences, fluorescent probes, Catalytic Domain, Acute lymphocytic leukemia, inhibitors, medicine, Humans, Cytotoxic T cell, Proteasome endopeptidase complex, activity-based protein profiling, 030304 developmental biology, 0303 health sciences, Chemistry, 010405 organic chemistry, Activity-based proteomics, General Chemistry, General Medicine, medicine.disease, Molecular biology, 3. Good health, 0104 chemical sciences, 030104 developmental biology, proteasome, Proteasome, Molecular Probes, Cancer research, Molecular probe
Full Text Finder 
Find this issue from the American Chemical Society