نتائج البحث - "Germinal Center/immunology"

1

A TLR7/8 Agonist-Including DOEPC-Based Cationic Liposome Formulation Mediates Its Adjuvanticity Through the Sustained Recruitment of Highly Activated Monocytes in a Type I IFN-Independent but NF-κB-Dependent Manner

المؤلفون: Elodie Belnoue, Floriane Auderset, Paul-Henri Lambert, Claire-Anne Siegrist, Beatris Mastelic-Gavillet

المصدر: Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Frontiers in immunology, Vol. 11 (2020) P. 580974

مصطلحات موضوعية: 0301 basic medicine, follicular T helper cells, Signal Transduction / immunology, Th1 Cells / immunology, Receptor, Interferon alpha-beta, ddc:616.07, Receptor, Interferon alpha-beta / genetics, Ligands, B-Lymphocytes / immunology, Monocytes, NF-kappa B / immunology, chemistry.chemical_compound, Mice, 0302 clinical medicine, germinal centers, Immunology and Allergy, Cationic liposome, Receptor, Original Research, Mice, Knockout, B-Lymphocytes, ddc:618, Membrane Glycoproteins, TLR7/8 agonist, NF-kappa B, T helper cell, Cell biology, Liposome, medicine.anatomical_structure, Interferon Type I, liposome, Phosphatidylcholines, Germinal centers, Adjuvants, Immunologic / administration & dosage, Follicular T helper cells, Heterocyclic Compounds, 3-Ring, Stearic Acids, Signal Transduction, lcsh:Immunologic diseases. Allergy, Liposomes / administration & dosage, Stearic Acids / administration & dosage, Interferon Type I / immunology, Drug Compounding, NF-kappa B / deficiency, Immunology, Membrane Glycoproteins / agonists, Phosphatidylcholines / administration & dosage, Toll-Like Receptor 7 / agonists, 03 medical and health sciences, Adjuvants, Immunologic, Immunity, Adjuvanticity, medicine, Dendritic Cells / immunology, Animals, adjuvants for vaccine, Receptor, Interferon alpha-beta / immunology, Adjuvants for vaccine, Heterocyclic Compounds, 3-Ring / administration & dosage, Toll-Like Receptor 8 / agonists, Germinal center, NF-κB, TLR7, Dendritic Cells, Th1 Cells, Monocytes / immunology, Germinal Center, Immunity, Innate, NF-kappa B / genetics, Mice, Inbred C57BL, Germinal Center / immunology, 030104 developmental biology, Receptor, Interferon alpha-beta / deficiency, chemistry, Toll-Like Receptor 7, Toll-Like Receptor 8, Liposomes, lcsh:RC581-607, 030215 immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5f1c233b620dd8097cc5e8f96b6438c
https://www.frontiersin.org/articles/10.3389/fimmu.2020.580974/full

2

The adjuvant GLA-SE promotes human Tfh cell expansion and emergence of public TCRβ clonotypes

المؤلفون: Steven W. Wingett, Kassim Kamaka, Danika L. Hill, Martin S. Zand, Jiong Wang, Elizabeth F. Wallin, Catherine Mkindi, François Spertini, Wim Pierson, Régine Audran, Daniel J. Bolland, Said Jongo, Sophie Houard, Michelle A. Linterman, Anne E. Corcoran, Edward J. Carr, Claudia Daubenberger

المساهمون: Hill, Danika L [0000-0001-6284-7061], Carr, Edward [0000-0001-9343-4593], Corcoran, Anne Elizabeth [0000-0002-9577-5313], Linterman, Michelle [0000-0001-6047-1996], Apollo - University of Cambridge Repository

المصدر: The Journal of experimental medicine, vol. 216, no. 8, pp. 1857-1873
The Journal of Experimental Medicine

مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_treatment, Receptors, Antigen, T-Cell, alpha-beta, Aluminum Hydroxide, Antibodies, Viral, Immunoglobulin G, 0302 clinical medicine, Glucosides, Immunology and Allergy, Research Articles, Cells, Cultured, Aged, 80 and over, education.field_of_study, B-Lymphocytes, Malaria vaccine, Vaccination, T-Lymphocytes, Helper-Inducer, Middle Aged, 3. Good health, Lipid A, Influenza Vaccines, 030220 oncology & carcinogenesis, Female, Adjuvant, Adult, Adolescent, Drug Compounding, Immunology, Population, Plasmodium falciparum, Antigens, Protozoan, Biology, Adjuvants, Immunologic/pharmacology, Aged, Aluminum Hydroxide/pharmacology, Antibodies, Viral/drug effects, Antibodies, Viral/immunology, Antigens, Protozoan/immunology, B-Lymphocytes/immunology, Drug Compounding/methods, Germinal Center/immunology, Glucosides/pharmacology, Humans, Immunity, Humoral/immunology, Influenza Vaccines/immunology, Lipid A/pharmacology, Lymph Nodes/immunology, Malaria Vaccines/immunology, Plasmodium falciparum/immunology, Receptors, Antigen, T-Cell, alpha-beta/genetics, Receptors, Antigen, T-Cell, alpha-beta/metabolism, T-Lymphocytes, Helper-Inducer/immunology, Vaccination/methods, Young Adult, Article, 03 medical and health sciences, Antigen, Adjuvants, Immunologic, parasitic diseases, Malaria Vaccines, medicine, education, Germinal center, Germinal Center, Immunity, Humoral, 030104 developmental biology, Humoral immunity, biology.protein, Lymph Nodes

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c02643e911e2eb9a88542a1b440cd038
https://serval.unil.ch/notice/serval:BIB_B9B6A1FE4844

3

Lymph node migratory dendritic cells modulate HIV-1 transcription through PD-1 engagement

المؤلفون: Riddhima Banga, Khalid Ohmiti, Matthieu Perreau, Kalliopi Ioannidou, Laurence de Leval, Francesco A. Procopio, Caterina Rebecchini, Alessandra Noto, Matthias Cavassini, Olivia Munoz, Giuseppe Pantaleo, Craig Fenwick, Jean-Marc Corpataux

المصدر: PLoS pathogens, vol. 15, no. 7, pp. e1007918
PLoS Pathogens, Vol 15, Iss 7, p e1007918 (2019)
PLoS Pathogens

مصطلحات موضوعية: RNA viruses, Transcription, Genetic, Physiology, Cell, Programmed Cell Death 1 Receptor, HIV Infections, Pathology and Laboratory Medicine, Memory T cells, White Blood Cells, Immunodeficiency Viruses, Transcription (biology), Cell Movement, Animal Cells, Medicine and Health Sciences, CD155, Receptors, Immunologic, Biology (General), Lymph node, 0303 health sciences, biology, Virulence, 030302 biochemistry & molecular biology, T-Lymphocytes, Helper-Inducer, Cell biology, Body Fluids, medicine.anatomical_structure, Blood, Cellular Microenvironment, Medical Microbiology, Viral Pathogens, Viruses, Anti-HIV Agents/therapeutic use, Antibodies, Monoclonal, Humanized/administration & dosage, Cell Movement/immunology, Cellular Microenvironment/immunology, Coculture Techniques, Dendritic Cells/immunology, Dendritic Cells/virology, Germinal Center/immunology, Germinal Center/virology, HIV Infections/drug therapy, HIV Infections/immunology, HIV Infections/virology, HIV-1/genetics, HIV-1/immunology, HIV-1/pathogenicity, Host Microbial Interactions/immunology, Humans, In Vitro Techniques, Lymph Nodes/immunology, Lymph Nodes/virology, Programmed Cell Death 1 Ligand 2 Protein/metabolism, Programmed Cell Death 1 Receptor/antagonists & inhibitors, Programmed Cell Death 1 Receptor/metabolism, Receptors, Immunologic/metabolism, Receptors, Virus/metabolism, T-Lymphocytes, Helper-Inducer/immunology, T-Lymphocytes, Helper-Inducer/virology, Receptors, Virus, Pathogens, Cellular Types, Anatomy, Research Article, Anti-HIV Agents, QH301-705.5, Immune Cells, Immunology, T cells, Antibodies, Monoclonal, Humanized, Microbiology, Lymphatic System, 03 medical and health sciences, TIGIT, Virology, Retroviruses, Genetics, medicine, T Helper Cells, Interleukin-7 receptor, Molecular Biology, Microbial Pathogens, 030304 developmental biology, Blood Cells, Host Microbial Interactions, Lentivirus, Organisms, Germinal center, Biology and Life Sciences, HIV, Dendritic Cells, Cell Biology, RC581-607, Germinal Center, Programmed Cell Death 1 Ligand 2 Protein, Immune checkpoint, Viral Replication, biology.protein, HIV-1, Parasitology, Lymph Nodes, Immunologic diseases. Allergy

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a75d9b74797de056653603fd5facae8
https://serval.unil.ch/resource/serval:BIB_1FF4BBBC8958.P001/REF.pdf

4

Maternal antibodies inhibit neonatal and infant responses to vaccination by shaping the early-life B cell repertoire within germinal centers

المؤلفون: Christiane S. Eberhardt, Paul-Henri Lambert, Maria Vono, Sylvain Lemeille, Dennis Christensen, Beatris Mastelic-Gavillet, Claire-Anne Siegrist, Floriane Auderset, Peter Andersen

المصدر: Cell Reports, Vol. 28, No 7 (2019) pp. 1773-1784.e5
Vono, M, Eberhardt, C S, Auderset, F, Mastelic-Gavillet, B, Lemeille, S, Christensen, D, Andersen, P, Lambert, P H & Siegrist, C A 2019, ' Maternal Antibodies Inhibit Neonatal and Infant Responses to Vaccination by Shaping the Early-Life B Cell Repertoire within Germinal Centers ', Cell Reports, vol. 28, no. 7, pp. 1773-1784.e5 . https://doi.org/10.1016/j.celrep.2019.07.047
Cell Reports, Vol 28, Iss 7, Pp 1773-1784.e5 (2019)

مصطلحات موضوعية: 0301 basic medicine, Male, Antibody Formation/immunology, T-Lymphocytes, ddc:616.07, Antibodies, Viral, Inbred C57BL, Mice, 0302 clinical medicine, Orthomyxoviridae Infections/immunology/virology, Pregnancy, germinal centers, Gene expression, Maternal-Fetal Exchange, lcsh:QH301-705.5, Inbred BALB C, B-Lymphocytes, Mice, Inbred BALB C, Orthomyxoviridae/immunology, biology, Helper-Inducer/immunology, Vaccination, repertoire, B-Lymphocytes/immunology, T-Lymphocytes, Helper-Inducer, Orthomyxoviridae, 3. Good health, Antibodies/blood/immunology, epitope masking, medicine.anatomical_structure, Female, Antibody, Offspring, General Biochemistry, Genetics and Molecular Biology, Antibodies, 03 medical and health sciences, Germinal Center/immunology, Orthomyxoviridae Infections, medicine, Animals, Gene, B cell, Germinal center, Maternal-Fetal Exchange/immunology, Germinal Center, Newborn, neonates, Mice, Inbred C57BL, 030104 developmental biology, maternal antibodies, Immunoglobulin class switching, Immunization, Animals, Newborn, lcsh:Biology (General), Immunology, Antibody Formation, biology.protein, Viral/blood/immunology, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::634bcd4fc3dafb5374f8c4aa9c1a163c
https://archive-ouverte.unige.ch/unige:143451

View record from ScienceDirect

5

MF59 Mediates Its B Cell Adjuvanticity by Promoting T Follicular Helper Cells and Thus Germinal Center Responses in Adult and Early Life

المؤلفون: Claire-Anne Siegrist, Paul-Henri Lambert, Flora Castellino, Floriane Auderset, Anja Seubert, Beatris Mastelic Gavillet, Giuseppe Del Giudice, John S. Tregoning, Ennio De Gregorio, Christiane S. Eberhardt

المصدر: J Immunol
Journal of Immunology, Vol. 194, No 10 (2015) pp. 4836-4845

مصطلحات موضوعية: Squalene, medicine.medical_treatment, Immunology, MF59, Polysorbates, Hemagglutinin (influenza), Enzyme-Linked Immunosorbent Assay, ddc:616.07, Real-Time Polymerase Chain Reaction, Mice, 03 medical and health sciences, Germinal Center/immunology, Influenza A Virus, H1N1 Subtype, 0302 clinical medicine, T-Lymphocytes, Helper-Inducer/immunology, Adjuvants, Immunologic, Adjuvants, Immunologic/pharmacology, Adjuvanticity, medicine, Squalene/immunology/pharmacology, Animals, Immunology and Allergy, B cell, 030304 developmental biology, 0303 health sciences, ddc:618, biology, Effector, Polysorbates/pharmacology, Germinal center, T-Lymphocytes, Helper-Inducer, Influenza Vaccines/immunology, Flow Cytometry, Germinal Center, Immunohistochemistry, 3. Good health, medicine.anatomical_structure, Influenza A Virus, H1N1 Subtype/immunology, Animals, Newborn, Immunization, Influenza Vaccines, biology.protein, Adjuvant, 030215 immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abca0938f0b186e151fbb5a3aa2fd758
https://doi.org/10.4049/jimmunol.1402071

6

Impairment of both IRE1 expression and XBP1 activation is a hallmark of GCB DLBCL and contributes to tumor growth

المؤلفون: Sonia T. Chelbi, Rémy Tallant, Bojan Bujisic, Léa Zaffalon, Francesco Bertoni, Fabio Martinon, Aude De Gassart, Michel Gilliet, Olivier Demaria

المصدر: Blood, vol. 129, no. 17, pp. 2420-2428

مصطلحات موضوعية: 0301 basic medicine, X-Box Binding Protein 1, Indazoles, Mice, 129 Strain, Leupeptins, Pyridones, Cellular differentiation, Immunology, Plasma Cells, Repressor, Biology, Protein Serine-Threonine Kinases, Animals, B-Lymphocytes/immunology, B-Lymphocytes/pathology, Cell Differentiation, Cell Line, Tumor, Cell Proliferation, Endoribonucleases/antagonists & inhibitors, Endoribonucleases/genetics, Endoribonucleases/immunology, Enhancer of Zeste Homolog 2 Protein/antagonists & inhibitors, Enhancer of Zeste Homolog 2 Protein/genetics, Enhancer of Zeste Homolog 2 Protein/immunology, Epigenesis, Genetic, Gene Expression Regulation, Neoplastic, Germinal Center/immunology, Germinal Center/pathology, Histones/genetics, Histones/immunology, Humans, Indazoles/pharmacology, Leupeptins/pharmacology, Lymphoma, Large B-Cell, Diffuse/genetics, Lymphoma, Large B-Cell, Diffuse/immunology, Lymphoma, Large B-Cell, Diffuse/pathology, Lymphoma, Large B-Cell, Diffuse/therapy, Mice, Plasma Cells/immunology, Plasma Cells/pathology, Promoter Regions, Genetic, Protein-Serine-Threonine Kinases/antagonists & inhibitors, Protein-Serine-Threonine Kinases/genetics, Protein-Serine-Threonine Kinases/immunology, Pyridones/pharmacology, RNA, Messenger/antagonists & inhibitors, RNA, Messenger/genetics, RNA, Messenger/immunology, Signal Transduction, X-Box Binding Protein 1/antagonists & inhibitors, X-Box Binding Protein 1/genetics, X-Box Binding Protein 1/immunology, Xenograft Model Antitumor Assays, Biochemistry, Histones, 03 medical and health sciences, hemic and lymphatic diseases, Gene expression, Endoribonucleases, Enhancer of Zeste Homolog 2 Protein, RNA, Messenger, Regulation of gene expression, B-Lymphocytes, EZH2, Germinal center, Cell Biology, Hematology, Germinal Center, Molecular biology, 030104 developmental biology, Histone methyltransferase, Cancer research, Lymphoma, Large B-Cell, Diffuse, Signal transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::764429660fa3aea64dcc02798d1d4e15
https://pubmed.ncbi.nlm.nih.gov/28450573

7

Altered Affinity Maturation in Primary Response to (4-hydroxy-3-nitrophenyl) Acetyl (NP) after Autologous Reconstitution of Irradiated C57BL/6 Mice

المؤلفون: Jacques Urbain, Annette Van Acker, Maryse Brait, Carl De Trez, Georgette Vansanten

المساهمون: Cellular and Molecular Immunology, Department of Bio-engineering Sciences

المصدر: Clinical and Developmental Immunology, Vol 9, Iss 3, Pp 119-125 (2002)
Developmental Immunology, 9 (3
Vrije Universiteit Brussel
Developmental Immunology

مصطلحات موضوعية: lcsh:Immunologic diseases. Allergy, T-Lymphocytes, Immunology, Antibody Affinity, Biology, Antibodies, Immunoglobulin G, Nitrophenols, Affinity maturation, Spleen -- immunology -- radiation effects, Mice, Antigen, Animals, T-Lymphocytes -- immunology -- radiation effects, Phenylacetates, Lymphopenic environment, Immunoglobulin G -- blood -- immunology, B-Lymphocytes, Germinal Center -- immunology -- radiation effects, Germinal center, Nitrophenols -- administration & dosage -- immunology, Sciences bio-médicales et agricoles, NP system, Germinal Center, Primary and secondary antibodies, Molecular biology, Antibody Affinity -- radiation effects, Haptens -- immunology, Mice, Inbred C57BL, Immunoglobulin class switching, Radiation Chimera, Antibodies -- blood -- immunology, biology.protein, B-Lymphocytes -- immunology -- radiation effects, Immunization, Germinal centers, Irradiation, Antibody, lcsh:RC581-607, Haptens, Hapten, Spleen, Research Article, Developmental Biology

وصف الملف: 2 full-text file(s): application/pdf; application/pdf; text/xhtml

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c31dea15168c89f17eb90e79b651c81
https://doaj.org/article/567a2261ac6043e4a877de9b8c470aee

8

Abortive T Follicular Helper Development Is Associated with a Defective Humoral Response in Leishmania infantum-Infected Macaques

المؤلفون: Ali Ouaissi, Ana Correia-de-Oliveira, Ricardo Jorge Dinis-Oliveira, Laure Campillo-Gimenez, Calaiselvy Soundaramourty, Jérôme Estaquier, Mireille Laforge, Ricardo Silvestre, Vasco Rodrigues, Anabela Cordeiro-da-Silva

المساهمون: Instituto de Investigação e Inovação em Saúde, CNRS FR3636, Faculty of Medecine des Saint-Pères, Paris Descartes University , Paris , France.

المصدر: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2014, 10 (4), pp.e1004096. ⟨10.1371/journal.ppat.1004096⟩
PLoS Pathogens, Vol 10, Iss 4, p e1004096 (2014)

مصطلحات موضوعية: Male, B Cells, [SDV]Life Sciences [q-bio], Spleen/parasitology, Receptors, CXCR5/immunology, Protozoology, Germinal Center/pathology, Biochemistry, Th1 Cells/pathology, White Blood Cells, 0302 clinical medicine, Animal Cells, Lymphoid Organs, Leishmania infantum, Memory B cell, lcsh:QH301-705.5, ComputingMilieux_MISCELLANEOUS, Protozoans, Leishmania, 0303 health sciences, education.field_of_study, Immune System Proteins, T Cells, Spleen/pathology, 3. Good health, Interleukin-10, medicine.anatomical_structure, Proto-Oncogene Proteins c-bcl-6, Leishmaniasis, Visceral, Cytokines, Female, Anatomy, Cellular Types, Research Article, lcsh:Immunologic diseases. Allergy, Receptors, CXCR5, Spleen/immunology, Immune Cells, Population, Immunology, Leishmaniasis, Visceral/pathology, Spleen, Immunopathology, Biology, Microbiology, Antibodies, Lymphatic System, Immune Activation, 03 medical and health sciences, Immune system, Germinal Center/immunology, Virology, Genetics, medicine, Animals, Proto-Oncogene Proteins c-bcl-6/immunology, Th1 Cells/immunology, education, Antibody-Producing Cells, Molecular Biology, B cell, 030304 developmental biology, Blood Cells, Gene Expression Regulation/immunology, Leishmania infantum/immunology, Germinal Center/parasitology, Organisms, Immunity, Germinal center, Biology and Life Sciences, Proteins, Cell Biology, Th1 Cells, Molecular Development, biology.organism_classification, Germinal Center, Macaca mulatta, Parasitic Protozoans, Acquired Immune System, Immunity, Humoral, Leishmaniasis, Visceral/immunology, Chronic infection, lcsh:Biology (General), Gene Expression Regulation, Immune System, Humoral Immunity, Parasitology, Clinical Immunology, lcsh:RC581-607, Interleukin-10/immunology, 030215 immunology, Developmental Biology