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1دورية أكاديمية
المؤلفون: Geza Ambrus-Aikelin, Katsuyuki Takeda, Anthony Joetham, Milos Lazic, Davide Povero, Angelina M. Santini, Rama Pranadinata, Casey D. Johnson, Matthew D. McGeough, Federico C. Beasley, Ryan Stansfield, Christopher McBride, Lynnie Trzoss, Hal M. Hoffman, Ariel E. Feldstein, Jeffrey A. Stafford, James M. Veal, Gretchen Bain, Erwin W. Gelfand
المصدر: Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2045-2322
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2دورية أكاديمية
المؤلفون: Geza Ambrus-Aikelin, Katsuyuki Takeda, Anthony Joetham, Milos Lazic, Davide Povero, Angelina M. Santini, Rama Pranadinata, Casey D. Johnson, Matthew D. McGeough, Federico C. Beasley, Ryan Stansfield, Christopher McBride, Lynnie Trzoss, Hal M. Hoffman, Ariel E. Feldstein, Jeffrey A. Stafford, James M. Veal, Gretchen Bain, Erwin W. Gelfand
المصدر: Scientific Reports, Vol 13, Iss 1, Pp 1-1 (2023)
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2045-2322
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3
المؤلفون: Christopher McBride, Lynnie Trzoss, Davide Povero, Milos Lazic, Geza Ambrus-Aikelin, Angelina Santini, Rama Pranadinata, Gretchen Bain, Ryan Stansfield, Jeffrey A. Stafford, James Veal, Ryan Takahashi, Justin Ly, Shu Chen, Liling Liu, Marika Nespi, Robert Blake, Arna Katewa, Tracy Kleinheinz, Swathi Sujatha-Bhaskar, Nandhini Ramamoorthi, Jessica Sims, Brent McKenzie, Mark Chen, Mark Ultsch, Matthew Johnson, Jeremy Murray, Claudio Ciferri, Steven T. Staben, Michael J. Townsend, Craig E. Stivala
المصدر: Journal of Medicinal Chemistry. 65:14721-14739
مصطلحات موضوعية: Drug Discovery, Molecular Medicine
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4
المؤلفون: Masanori Okaniwa, Daisuke Morishita, Michael G. Klein, Yuta Tanaka, Bunnai Saito, Shigemitsu Matsumoto, Shinichi Imamura, Hiromichi Kimura, Geza Ambrus-Aikelin, Noriko Uchiyama, Osamu Kurasawa, Akihiro Yokota
المصدر: ACS Medicinal Chemistry Letters
مصطلحات موضوعية: Letter, Allosteric regulation, nicotinamide adenine dinucleotide (NAD), DHPS, 01 natural sciences, Biochemistry, chemistry.chemical_compound, spermidine, parasitic diseases, Drug Discovery, Deoxyhypusine synthase, Hypusine, chemistry.chemical_classification, allosteric inhibitor, biology, Functional analysis, 010405 organic chemistry, Organic Chemistry, 0104 chemical sciences, Spermidine, 010404 medicinal & biomolecular chemistry, Enzyme, chemistry, Deoxyhypusine synthase (DHPS), biology.protein, EIF5A, eukaryotic translation initiation factor 5A (eIF5A)
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5
المؤلفون: Masanori Okaniwa, Geza Ambrus-Aikelin, Shigemitsu Matsumoto, Yuta Tanaka, Akihiro Yokota, Koji Ono, Kazumasa Ogawa, Daisuke Morishita, Satoshi Kitazawa, Osamu Kurasawa, Michael G. Klein, Shinichi Imamura, Hiromichi Kimura, Noriko Uchiyama, Bunnai Saito
المصدر: Journal of Medicinal Chemistry. 63:3215-3226
مصطلحات موضوعية: Conformational change, Guanine, Indoles, Protein Conformation, Spermidine, Allosteric regulation, DHPS, Thiophenes, Crystallography, X-Ray, Structure-Activity Relationship, chemistry.chemical_compound, parasitic diseases, Drug Discovery, Humans, Deoxyhypusine synthase, Enzyme Inhibitors, Enzyme Assays, Hypusine, Oxidoreductases Acting on CH-NH Group Donors, Molecular Structure, biology, NAD, High-Throughput Screening Assays, Biochemistry, chemistry, biology.protein, Molecular Medicine, NAD+ kinase, EIF5A, Allosteric Site, Protein Binding
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6
المؤلفون: Ryokichi Koyama, Geza Ambrus-Aikelin, Darbi Witmer, Bi-Ching Sang, Yasunori Fukuda, Hidehisa Iwata, Hideyuki Nakagawa, Masaharu Nakayama, Yusuke Kamada
المصدر: ASSAY and Drug Development Technologies. 16:194-204
مصطلحات موضوعية: Orphan receptor, Sulfonamides, Reporter gene, Hydrocarbons, Fluorinated, Molecular Structure, Chemistry, Cholesterol binding, Drug Evaluation, Preclinical, Nuclear Receptor Subfamily 1, Group F, Member 3, Spodoptera, Pharmacology, Cholesterol, RAR-related orphan receptor gamma, Drug Discovery, Coactivator, Sf9 Cells, Animals, Humans, Th17 Cells, Molecular Medicine, Inverse agonist, lipids (amino acids, peptides, and proteins), Receptor, IC50
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59d9bc10dbf1390655dbeac60d89a052
https://doi.org/10.1089/adt.2018.852 -
7
المؤلفون: Ryoukichi Koyama, Geza Ambrus-Aikelin, Hideyuki Nakagawa, Satoshi Yamamoto, Masaharu Nakayama, Junya Shirai, Bi-Ching Sang, Atsuko Ochida, Yusuke Kamada, Mitsunori Kono
المصدر: Pharmacology. 102(5-6)
مصطلحات موضوعية: 0301 basic medicine, Transcriptional Activation, Jurkat cells, Chromatography, Affinity, Proinflammatory cytokine, 03 medical and health sciences, Jurkat Cells, Mice, 0302 clinical medicine, RAR-related orphan receptor gamma, Fluorescence Resonance Energy Transfer, Inverse agonist, Animals, Humans, Sulfones, Receptor, Benzofurans, Pharmacology, Orphan receptor, Chemistry, Ligand binding assay, Interleukin-17, General Medicine, Orphan Nuclear Receptors, Kinetics, 030104 developmental biology, Cancer research, Interleukin 17, 030217 neurology & neurosurgery, Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e01f8f36fc87c5de90008ec945ff7253
https://pubmed.ncbi.nlm.nih.gov/30134246