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المؤلفون: Won KD; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Unity Health Toronto, Toronto, Ontario, Canada.; Department of Medicine and Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.; Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Gil Gonzalez L; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Unity Health Toronto, Toronto, Ontario, Canada., Cruz-Leal Y; Innovation and Portfolio Management, Canadian Blood Services, Ottawa, Ontario, Canada., Pavon Oro A; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Unity Health Toronto, Toronto, Ontario, Canada., Lazarus AH; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Unity Health Toronto, Toronto, Ontario, Canada.; Department of Medicine and Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.; Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.; Innovation and Portfolio Management, Canadian Blood Services, Ottawa, Ontario, Canada.

المصدر: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2024 May 15; Vol. 212 (10), pp. 1531-1539.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association of Immunologists Country of Publication: United States NLM ID: 2985117R Publication Model: Print Cited Medium: Internet ISSN: 1550-6606 (Electronic) Linking ISSN: 00221767 NLM ISO Abbreviation: J Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Platelet Activating Factor*/immunology , Purpura, Thrombocytopenic, Idiopathic*/immunology , Purpura, Thrombocytopenic, Idiopathic*/drug therapy , Erythrocytes*/immunology , Inflammation*/immunology , Platelet Membrane Glycoproteins*/antagonists & inhibitors , Platelet Membrane Glycoproteins*/immunology , Chemokine CCL2*/immunology, Animals ; Mice ; Chemokine CCL5/immunology ; Chemokine CXCL9/immunology ; Receptors, G-Protein-Coupled/immunology ; Signal Transduction/immunology ; Mice, Inbred C57BL ; Autoantibodies/immunology ; Disease Models, Animal

المؤلفون: Gil Gonzalez L; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada., Won KD; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Tawhidi Z; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Cummins E; adMare BioInnovations, Vancouver, BC, Canada., Cruz-Leal Y; Innovation and Portfolio Management, Canadian Blood Services, Ottawa, ON, Canada., Tundidor Cabado Y; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada., Sachs UJ; Institute for Clinical Immunology, Transfusion Medicine, and Haemostasis, Justus Liebig University, Giessen, Germany.; Department of Thrombosis and Haemostasis, Giessen University Hospital, Giessen, Germany., Norris PAA; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada., Shan Y; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada., Bhakta V; Innovation and Portfolio Management, Canadian Blood Services, Ottawa, ON, Canada., Li J; adMare BioInnovations, Vancouver, BC, Canada., Samudio I; adMare BioInnovations, Vancouver, BC, Canada., Silva-Moreno B; adMare BioInnovations, Vancouver, BC, Canada., Cerna-Portillo L; adMare BioInnovations, Vancouver, BC, Canada., Pavon Oro A; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada., Bergqvist P; adMare BioInnovations, Vancouver, BC, Canada., Chan P; adMare BioInnovations, Vancouver, BC, Canada., Moorehead A; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada., Sholzberg M; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Sheffield WP; Innovation and Portfolio Management, Canadian Blood Services, Ottawa, ON, Canada., Lazarus AH; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.; Innovation and Portfolio Management, Canadian Blood Services, Ottawa, ON, Canada.

المصدر: Blood advances [Blood Adv] 2024 Apr 23; Vol. 8 (8), pp. 1869-1879.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE

مواضيع طبية MeSH: Purpura, Thrombocytopenic, Idiopathic*/drug therapy , Thrombocytopenia*, Humans ; Mice ; Animals ; Receptors, IgG/metabolism ; Disease Models, Animal ; Immunoglobulin G/therapeutic use ; Albumins/therapeutic use

المؤلفون: Norris PAA; Innovation and Portfolio Management, Canadian Blood Services, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada.; Toronto Platelet Immunobiology Group, Toronto, ON, Canada., Tawhidi Z; Innovation and Portfolio Management, Canadian Blood Services, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada.; Toronto Platelet Immunobiology Group, Toronto, ON, Canada., Sachs UJ; Institute for Clinical Immunology, Transfusion Medicine, and Haemostasis, Justus Liebig University, Giessen, Germany.; Department of Thrombosis and Haemostasis, Giessen University Hospital, Giessen, Germany., Cserti-Gazdewich CM; Innovation and Portfolio Management, Canadian Blood Services, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; Laboratory Medicine Program, University Health Network, Toronto, ON, Canada.; University of Toronto Quality in Utilization, Education and Safety in Transfusion Research Program, University of Toronto, Toronto, ON, Canada., Lin Y; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; University of Toronto Quality in Utilization, Education and Safety in Transfusion Research Program, University of Toronto, Toronto, ON, Canada.; Precision Diagnostics and Therapeutics Program, Sunnybrook Health Sciences Centre, Toronto, Canada., Callum J; Innovation and Portfolio Management, Canadian Blood Services, Toronto, ON, Canada.; University of Toronto Quality in Utilization, Education and Safety in Transfusion Research Program, University of Toronto, Toronto, ON, Canada.; Department of Pathology and Molecular Medicine, Kingston Health Sciences Centre and Queen's University, Kingston, ON, Canada., Gil Gonzalez L; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada.; Toronto Platelet Immunobiology Group, Toronto, ON, Canada., Shan Y; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada.; Toronto Platelet Immunobiology Group, Toronto, ON, Canada., Branch DR; Innovation and Portfolio Management, Canadian Blood Services, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada.; University of Toronto Quality in Utilization, Education and Safety in Transfusion Research Program, University of Toronto, Toronto, ON, Canada.; Department of Medicine, University of Toronto, Toronto, ON, Canada.; Division of Hematology, Department of Medicine, University of Toronto, Toronto, ON, Canada., Lazarus AH; Innovation and Portfolio Management, Canadian Blood Services, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada.; Toronto Platelet Immunobiology Group, Toronto, ON, Canada.; University of Toronto Quality in Utilization, Education and Safety in Transfusion Research Program, University of Toronto, Toronto, ON, Canada.; Department of Medicine, University of Toronto, Toronto, ON, Canada.

المصدر: Blood advances [Blood Adv] 2023 Jul 25; Vol. 7 (14), pp. 3561-3572.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE

مواضيع طبية MeSH: Purpura, Thrombocytopenic, Idiopathic*/diagnosis , Thrombocytopenia*/metabolism, Humans ; Blood Platelets/metabolism ; Platelet Glycoprotein GPIIb-IIIa Complex/metabolism ; Immunoglobulin G ; Phagocytosis ; Macrophages/metabolism ; Autoantibodies

المؤلفون: Gil Gonzalez L; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Unity Health Toronto, Toronto ON, Canada., Fernandez-Marrero Y; Biological Sciences, Sunnybrook Research Institute, Toronto, ON, Canada., Norris PAA; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Unity Health Toronto, Toronto ON, Canada.; Innovation and Portfolio Management, Canadian Blood Services, Ottawa, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Tawhidi Z; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Unity Health Toronto, Toronto ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Shan Y; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Unity Health Toronto, Toronto ON, Canada., Cruz-Leal Y; Innovation and Portfolio Management, Canadian Blood Services, Ottawa, ON, Canada., Won KD; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Unity Health Toronto, Toronto ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Frias-Boligan K; Innovation and Portfolio Management, Canadian Blood Services, Ottawa, ON, Canada., Branch DR; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Unity Health Toronto, Toronto ON, Canada.; Innovation and Portfolio Management, Canadian Blood Services, Ottawa, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; Department of Medicine, University of Toronto, Toronto, ON, Canada., Lazarus AH; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Unity Health Toronto, Toronto ON, Canada.; Innovation and Portfolio Management, Canadian Blood Services, Ottawa, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; Department of Medicine, University of Toronto, Toronto, ON, Canada.

المصدر: PloS one [PLoS One] 2022 Dec 14; Vol. 17 (12), pp. e0278365. Date of Electronic Publication: 2022 Dec 14 (Print Publication: 2022).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, IgG*/metabolism , Immunoglobulin G*, Humans ; THP-1 Cells ; Phagocytosis ; Monocytes/metabolism ; Erythrocytes/metabolism