-
1
المؤلفون: Jorge D. Brioni, Tracy L. Carr, Gin C. Hsieh, Madhavi Pai, Lawrence A. Black, Tiffany Runyan Garrison, Cenchen Zhan, Marlon D. Cowart, Erica Gomez, Gilbert Diaz, Arlene M. Manelli, Marina I. Strakhova, Anthony Lee, Jill M. Wetter
المصدر: European Journal of Pharmacology. 684:87-94
مصطلحات موضوعية: Pharmacology, business.industry, Antagonist, chemistry.chemical_compound, Nociception, Pharmacokinetics, chemistry, Neuropathic pain, Potency, Medicine, Histamine H3 receptor, Receptor, business, Histamine
-
2Characterization of A-935142, a hERG enhancer, in the presence and absence of standard hERG blockers
المؤلفون: Bryan F. Cox, Xiaoqin Liu, Gary A. Gintant, James T. Limberis, Gilbert Diaz, Ruth L. Martin, Kathryn Houseman, Zhi Su
المصدر: Life Sciences. 90:607-611
مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, Patch-Clamp Techniques, Purkinje fibers, Voltage clamp, hERG, Acetates, Pharmacology, Tritium, General Biochemistry, Genetics and Molecular Biology, Phenethylamines, medicine, Humans, Terfenadine, cardiovascular diseases, Patch clamp, General Pharmacology, Toxicology and Pharmaceutics, Binding site, Analysis of Variance, Sulfonamides, biology, Chemistry, Sotalol, HEK 293 cells, General Medicine, Ether-A-Go-Go Potassium Channels, HEK293 Cells, medicine.anatomical_structure, biology.protein, Pyrazoles, medicine.drug
-
3
المؤلفون: Peter F. Bousquet, Daniel H. Albert, Gary A. Gintant, Patrick A. Marcotte, Gilbert Diaz, George A. Cunha, Ruth L. Martin, Kathryn Houseman, Stevan W. Djuric, Jürgen Dinges, Jennifer J. Bouska, Thomas J. Sowin, Paul Tapang, Charles W. Hutchins, Michael R. Michaelides, Kimba L. Ashworth, Eric F. Johnson, Henry Q. Zhang, Irini Akritopoulou-Zanze, Michelle Nyein, Arnold Lee D, Hu Li, Steven K. Davidsen, Alan F. Gasiecki, Christopher M. Harris, Vijaya Gracias, Zhi Su, Zhiren Xia
المصدر: Journal of Medicinal Chemistry. 50:2011-2029
مصطلحات موضوعية: Models, Molecular, ERG1 Potassium Channel, Patch-Clamp Techniques, Platelet-derived growth factor, hERG, Antineoplastic Agents, Thiophenes, Binding, Competitive, Cell Line, Mice, Radioligand Assay, Structure-Activity Relationship, chemistry.chemical_compound, Growth factor receptor, Drug Discovery, Animals, Edema, Humans, Receptors, Platelet-Derived Growth Factor, Uterine Diseases, Mice, Inbred BALB C, Estradiol, biology, Kinase, Stereoisomerism, Vascular Endothelial Growth Factor Receptor-2, Xenograft Model Antitumor Assays, Ether-A-Go-Go Potassium Channels, Potassium channel, Receptors, Vascular Endothelial Growth Factor, Indenes, Biochemistry, chemistry, Enzyme inhibitor, Alkynes, biology.protein, Pyrazoles, Molecular Medicine, Female, Signal transduction, Platelet-derived growth factor receptor, Protein Binding
-
4
المؤلفون: Ivan Milicic, Jorge D. Brioni, Deliang Zhou, Gerard B. Fox, Gerard D. Gagne, Ramin Faghih, Angela L. Molesky, Arthur A. Hancock, Kennan C. Marsh, Liping Pan, David G. Witte, Timothy A. Esbenshade, Jill M. Wetter, Kaitlin E. Browman, Michael J. Buckley, Gilbert Diaz, Xiaoqing Deng, Victoria A. Komater, John L. Baranowski, Thomas R. Miller, Marlon D. Cowart, Gregory A. Gfesser, Marilyn S. Diehl, Kathleen M. Krueger, Ellen M. Roberts
المصدر: Biochemical Pharmacology. 73:1243-1255
مصطلحات موضوعية: Pharmacology, Phospholipidosis, Behavior, Animal, biology, Chemistry, hERG, Histamine Antagonists, Biological activity, Haplorhini, Biochemistry, Rats, chemistry.chemical_compound, Dogs, Pharmacokinetics, In vivo, biology.protein, Animals, Humans, Receptors, Histamine H3, Histamine H3 receptor, Receptor, Histamine, Benzofurans
-
5
المؤلفون: Gilbert Diaz, Lee C. Preusser, Ann Mikhail, Christopher A. Ogiela, Lynch John K, Philip R. Kym, Lisa M. Hernández, Dariusz Wodka, Gang Zhao, Doug H. Falls, Eugene N. Bush, James S. Polakowski, Andrew S. Judd, Robin Shapiro, Hing L. Sham, James J. Napier, Christine A. Collins, Kennan C. Marsh, Victoria Knourek-Segel, Glenn A. Reinhart, Thomas J Campbell, Sevan Brodjian, Michael E. Brune, Brian A. Droz, Mathew M. Mulhern, Kathryn Houseman, Regina M. Reilly, Brian D. Dayton, Ryan M. Fryer, James T. Limberis, Rajesh R. Iyengar, Freeman Jennifer C
المصدر: Journal of Medicinal Chemistry. 49:6569-6584
مصطلحات موضوعية: medicine.medical_specialty, Potassium Channels, medicine.drug_class, Acylation, hERG, Blood Pressure, Carboxamide, Cell Line, Rats, Sprague-Dawley, Electrocardiography, Mice, Structure-Activity Relationship, Dogs, Pharmacokinetics, Heart Rate, In vivo, Internal medicine, Drug Discovery, medicine, Animals, Potency, Benzodioxoles, Receptors, Somatostatin, biology, Chemistry, Body Weight, Antagonist, Potassium channel, Rats, Melanin-concentrating hormone receptor, Mice, Inbred C57BL, Endocrinology, Cardiovascular Diseases, Chromones, Area Under Curve, biology.protein, Molecular Medicine, Calcium, Female, Indicators and Reagents, Half-Life
-
6
المؤلفون: Daryl R. Sauer, Jonathan Greer, Charles J. Nichols, Craig D. Wegner, Jason A. Segreti, Kurt M. Mohning, Fortuna Haviv, John T. Randolph, E N Bush, Philip L. Waid, Gilbert Diaz, Leslie M. Besecke, Gary Bammert
المصدر: Journal of Medicinal Chemistry. 47:1085-1097
مصطلحات موضوعية: Male, Models, Molecular, Stereochemistry, Administration, Oral, Pharmacology, Hormone antagonist, Chemical synthesis, Gonadotropin-Releasing Hormone, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Cricetinae, Drug Discovery, Animals, Humans, Receptor, Cells, Cultured, Hexoses, Cladinose, Chemistry, Antagonist, Biological activity, Erythromycin, Rats, Drug Design, Pituitary Gland, Injections, Intravenous, Molecular Medicine, Luteinizing hormone, Orchiectomy
-
7
المؤلفون: James S. Polakowski, Nathan L. Lubbers, Sandra E. Burke, Katina M Daniell, Bryan F. Cox, Craig D. Wegner, Gilbert Diaz
المصدر: European Journal of Pharmacology. 435:79-83
مصطلحات موضوعية: medicine.medical_specialty, Pyridines, Myocardial Infarction, Ischemia, Blood Pressure, Imides, Protective Agents, Heart Rate, Oral administration, Internal medicine, Heat shock protein, Heart rate, medicine, Animals, HSP70 Heat-Shock Proteins, Myocardial infarction, Pharmacology, business.industry, Myocardium, medicine.disease, Rats, Hsp70, Disease Models, Animal, Blood pressure, Endocrinology, Mechanism of action, Anesthesia, medicine.symptom, business
-
8
المؤلفون: Kurt M. Mohning, E N Bush, Van A. Cybulski, Craig D. Wegner, Gilbert Diaz, Randolph John, Mira Rao, Jason A. Segreti, Jonathan Greer, Fortuna Haviv, Philip L. Waid, Leslie M. Besecke
المصدر: Drug Development Research. 52:485-491
مصطلحات موضوعية: medicine.medical_specialty, Pituitary gland, medicine.drug_class, Antagonist, Peptide hormone, Pharmacology, Biology, Androgen, medicine.anatomical_structure, Endocrinology, Internal medicine, Drug Discovery, medicine, Gonadotropin, Luteinizing hormone, Receptor, Testosterone
-
9
المؤلفون: Marlon, Cowart, Gin, Hsieh, Lawrence A, Black, Cenchen, Zhan, Erica J, Gomez, Madhavi, Pai, Marina, Strakhova, Arlene, Manelli, Tracy, Carr, Jill, Wetter, Anthony, Lee, Gilbert, Diaz, Tiffany, Garrison, Jorge D, Brioni
المصدر: European journal of pharmacology. 684(1-3)
مصطلحات موضوعية: Male, Cell Membrane Permeability, Heart, Osteoarthritis, Knee, Ether-A-Go-Go Potassium Channels, Rats, Substrate Specificity, Pyridazines, Rats, Sprague-Dawley, Disease Models, Animal, Dogs, HEK293 Cells, Osteoarthritis, Animals, Cytochrome P-450 Enzyme Inhibitors, Humans, Neuralgia, Receptors, Histamine H3, Benzothiazoles, Histamine H3 Antagonists
-
10
المؤلفون: Ruth L. Martin, Lee C. Preusser, James T. Limberis, Michael Meyer, Michael J. Dart, Betty B. Yao, Jonathon Green, Xiaoqin Liu, Gary A. Gintant, Zhi Su, Bryan F. Cox, James S. Polakowski, Gilbert Diaz
المصدر: Current drug safety. 6(5)
مصطلحات موضوعية: Inotrope, Male, Sarcomeres, medicine.medical_specialty, Patch-Clamp Techniques, Calcium Channels, L-Type, Heart Ventricles, Toxicology, Sarcomere, Contractility, Receptor, Cannabinoid, CB2, Inhibitory Concentration 50, Dogs, Piperidines, Receptor, Cannabinoid, CB1, In vivo, Internal medicine, Myocyte, Medicine, Animals, Pharmacology (medical), Myocytes, Cardiac, Receptor, Pharmacology, business.industry, Antagonist, Myocardial Contraction, Thiazoles, Endocrinology, Benzamides, Ventricular pressure, Pyrazoles, Rabbits, Rimonabant, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af8945b9999e6d964885523337f00520
https://pubmed.ncbi.nlm.nih.gov/22424534