المؤلفون: Jorge D. Brioni, Tracy L. Carr, Gin C. Hsieh, Madhavi Pai, Lawrence A. Black, Tiffany Runyan Garrison, Cenchen Zhan, Marlon D. Cowart, Erica Gomez, Gilbert Diaz, Arlene M. Manelli, Marina I. Strakhova, Anthony Lee, Jill M. Wetter

المصدر: European Journal of Pharmacology. 684:87-94

مصطلحات موضوعية: Pharmacology, business.industry, Antagonist, chemistry.chemical_compound, Nociception, Pharmacokinetics, chemistry, Neuropathic pain, Potency, Medicine, Histamine H3 receptor, Receptor, business, Histamine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::54c0e87b77f27eefbbaad46501b1babe
https://doi.org/10.1016/j.ejphar.2012.03.048

المؤلفون: Bryan F. Cox, Xiaoqin Liu, Gary A. Gintant, James T. Limberis, Gilbert Diaz, Ruth L. Martin, Kathryn Houseman, Zhi Su

المصدر: Life Sciences. 90:607-611

مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, Patch-Clamp Techniques, Purkinje fibers, Voltage clamp, hERG, Acetates, Pharmacology, Tritium, General Biochemistry, Genetics and Molecular Biology, Phenethylamines, medicine, Humans, Terfenadine, cardiovascular diseases, Patch clamp, General Pharmacology, Toxicology and Pharmaceutics, Binding site, Analysis of Variance, Sulfonamides, biology, Chemistry, Sotalol, HEK 293 cells, General Medicine, Ether-A-Go-Go Potassium Channels, HEK293 Cells, medicine.anatomical_structure, biology.protein, Pyrazoles, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef24215cc71f2aa845920e90e5983a84
https://doi.org/10.1016/j.lfs.2012.02.017

المؤلفون: Peter F. Bousquet, Daniel H. Albert, Gary A. Gintant, Patrick A. Marcotte, Gilbert Diaz, George A. Cunha, Ruth L. Martin, Kathryn Houseman, Stevan W. Djuric, Jürgen Dinges, Jennifer J. Bouska, Thomas J. Sowin, Paul Tapang, Charles W. Hutchins, Michael R. Michaelides, Kimba L. Ashworth, Eric F. Johnson, Henry Q. Zhang, Irini Akritopoulou-Zanze, Michelle Nyein, Arnold Lee D, Hu Li, Steven K. Davidsen, Alan F. Gasiecki, Christopher M. Harris, Vijaya Gracias, Zhi Su, Zhiren Xia

المصدر: Journal of Medicinal Chemistry. 50:2011-2029

مصطلحات موضوعية: Models, Molecular, ERG1 Potassium Channel, Patch-Clamp Techniques, Platelet-derived growth factor, hERG, Antineoplastic Agents, Thiophenes, Binding, Competitive, Cell Line, Mice, Radioligand Assay, Structure-Activity Relationship, chemistry.chemical_compound, Growth factor receptor, Drug Discovery, Animals, Edema, Humans, Receptors, Platelet-Derived Growth Factor, Uterine Diseases, Mice, Inbred BALB C, Estradiol, biology, Kinase, Stereoisomerism, Vascular Endothelial Growth Factor Receptor-2, Xenograft Model Antitumor Assays, Ether-A-Go-Go Potassium Channels, Potassium channel, Receptors, Vascular Endothelial Growth Factor, Indenes, Biochemistry, chemistry, Enzyme inhibitor, Alkynes, biology.protein, Pyrazoles, Molecular Medicine, Female, Signal transduction, Platelet-derived growth factor receptor, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa7224e585fce7d1645dd21a1f5e3e55
https://doi.org/10.1021/jm061223o

المؤلفون: Ivan Milicic, Jorge D. Brioni, Deliang Zhou, Gerard B. Fox, Gerard D. Gagne, Ramin Faghih, Angela L. Molesky, Arthur A. Hancock, Kennan C. Marsh, Liping Pan, David G. Witte, Timothy A. Esbenshade, Jill M. Wetter, Kaitlin E. Browman, Michael J. Buckley, Gilbert Diaz, Xiaoqing Deng, Victoria A. Komater, John L. Baranowski, Thomas R. Miller, Marlon D. Cowart, Gregory A. Gfesser, Marilyn S. Diehl, Kathleen M. Krueger, Ellen M. Roberts

المصدر: Biochemical Pharmacology. 73:1243-1255

مصطلحات موضوعية: Pharmacology, Phospholipidosis, Behavior, Animal, biology, Chemistry, hERG, Histamine Antagonists, Biological activity, Haplorhini, Biochemistry, Rats, chemistry.chemical_compound, Dogs, Pharmacokinetics, In vivo, biology.protein, Animals, Humans, Receptors, Histamine H3, Histamine H3 receptor, Receptor, Histamine, Benzofurans

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc1120f3945a2a50635d43ffdb23648
https://doi.org/10.1016/j.bcp.2007.02.010

المؤلفون: Gilbert Diaz, Lee C. Preusser, Ann Mikhail, Christopher A. Ogiela, Lynch John K, Philip R. Kym, Lisa M. Hernández, Dariusz Wodka, Gang Zhao, Doug H. Falls, Eugene N. Bush, James S. Polakowski, Andrew S. Judd, Robin Shapiro, Hing L. Sham, James J. Napier, Christine A. Collins, Kennan C. Marsh, Victoria Knourek-Segel, Glenn A. Reinhart, Thomas J Campbell, Sevan Brodjian, Michael E. Brune, Brian A. Droz, Mathew M. Mulhern, Kathryn Houseman, Regina M. Reilly, Brian D. Dayton, Ryan M. Fryer, James T. Limberis, Rajesh R. Iyengar, Freeman Jennifer C

المصدر: Journal of Medicinal Chemistry. 49:6569-6584

مصطلحات موضوعية: medicine.medical_specialty, Potassium Channels, medicine.drug_class, Acylation, hERG, Blood Pressure, Carboxamide, Cell Line, Rats, Sprague-Dawley, Electrocardiography, Mice, Structure-Activity Relationship, Dogs, Pharmacokinetics, Heart Rate, In vivo, Internal medicine, Drug Discovery, medicine, Animals, Potency, Benzodioxoles, Receptors, Somatostatin, biology, Chemistry, Body Weight, Antagonist, Potassium channel, Rats, Melanin-concentrating hormone receptor, Mice, Inbred C57BL, Endocrinology, Cardiovascular Diseases, Chromones, Area Under Curve, biology.protein, Molecular Medicine, Calcium, Female, Indicators and Reagents, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b667ab564d57ac2f27112dd9382a72ab
https://doi.org/10.1021/jm060683e

المؤلفون: Daryl R. Sauer, Jonathan Greer, Charles J. Nichols, Craig D. Wegner, Jason A. Segreti, Kurt M. Mohning, Fortuna Haviv, John T. Randolph, E N Bush, Philip L. Waid, Gilbert Diaz, Leslie M. Besecke, Gary Bammert

المصدر: Journal of Medicinal Chemistry. 47:1085-1097

مصطلحات موضوعية: Male, Models, Molecular, Stereochemistry, Administration, Oral, Pharmacology, Hormone antagonist, Chemical synthesis, Gonadotropin-Releasing Hormone, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Cricetinae, Drug Discovery, Animals, Humans, Receptor, Cells, Cultured, Hexoses, Cladinose, Chemistry, Antagonist, Biological activity, Erythromycin, Rats, Drug Design, Pituitary Gland, Injections, Intravenous, Molecular Medicine, Luteinizing hormone, Orchiectomy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fabef2f09ac213c5e8373f774e466e4
https://doi.org/10.1021/jm030418i

المؤلفون: James S. Polakowski, Nathan L. Lubbers, Sandra E. Burke, Katina M Daniell, Bryan F. Cox, Craig D. Wegner, Gilbert Diaz

المصدر: European Journal of Pharmacology. 435:79-83

مصطلحات موضوعية: medicine.medical_specialty, Pyridines, Myocardial Infarction, Ischemia, Blood Pressure, Imides, Protective Agents, Heart Rate, Oral administration, Internal medicine, Heat shock protein, Heart rate, medicine, Animals, HSP70 Heat-Shock Proteins, Myocardial infarction, Pharmacology, business.industry, Myocardium, medicine.disease, Rats, Hsp70, Disease Models, Animal, Blood pressure, Endocrinology, Mechanism of action, Anesthesia, medicine.symptom, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b78ac2bcba8f49cc9f88e5bf2b58b4
https://doi.org/10.1016/s0014-2999(01)01552-7

المؤلفون: Kurt M. Mohning, E N Bush, Van A. Cybulski, Craig D. Wegner, Gilbert Diaz, Randolph John, Mira Rao, Jason A. Segreti, Jonathan Greer, Fortuna Haviv, Philip L. Waid, Leslie M. Besecke

المصدر: Drug Development Research. 52:485-491

مصطلحات موضوعية: medicine.medical_specialty, Pituitary gland, medicine.drug_class, Antagonist, Peptide hormone, Pharmacology, Biology, Androgen, medicine.anatomical_structure, Endocrinology, Internal medicine, Drug Discovery, medicine, Gonadotropin, Luteinizing hormone, Receptor, Testosterone

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::34863a63a9805da58bf9feed4e71ffc9
https://doi.org/10.1002/ddr.1150

المؤلفون: Marlon, Cowart, Gin, Hsieh, Lawrence A, Black, Cenchen, Zhan, Erica J, Gomez, Madhavi, Pai, Marina, Strakhova, Arlene, Manelli, Tracy, Carr, Jill, Wetter, Anthony, Lee, Gilbert, Diaz, Tiffany, Garrison, Jorge D, Brioni

المصدر: European journal of pharmacology. 684(1-3)

مصطلحات موضوعية: Male, Cell Membrane Permeability, Heart, Osteoarthritis, Knee, Ether-A-Go-Go Potassium Channels, Rats, Substrate Specificity, Pyridazines, Rats, Sprague-Dawley, Disease Models, Animal, Dogs, HEK293 Cells, Osteoarthritis, Animals, Cytochrome P-450 Enzyme Inhibitors, Humans, Neuralgia, Receptors, Histamine H3, Benzothiazoles, Histamine H3 Antagonists

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::764e1b80d58c593fcd9bbd7cfee9c6b9
https://pubmed.ncbi.nlm.nih.gov/22504024

المؤلفون: Ruth L. Martin, Lee C. Preusser, James T. Limberis, Michael Meyer, Michael J. Dart, Betty B. Yao, Jonathon Green, Xiaoqin Liu, Gary A. Gintant, Zhi Su, Bryan F. Cox, James S. Polakowski, Gilbert Diaz

المصدر: Current drug safety. 6(5)

مصطلحات موضوعية: Inotrope, Male, Sarcomeres, medicine.medical_specialty, Patch-Clamp Techniques, Calcium Channels, L-Type, Heart Ventricles, Toxicology, Sarcomere, Contractility, Receptor, Cannabinoid, CB2, Inhibitory Concentration 50, Dogs, Piperidines, Receptor, Cannabinoid, CB1, In vivo, Internal medicine, Myocyte, Medicine, Animals, Pharmacology (medical), Myocytes, Cardiac, Receptor, Pharmacology, business.industry, Antagonist, Myocardial Contraction, Thiazoles, Endocrinology, Benzamides, Ventricular pressure, Pyrazoles, Rabbits, Rimonabant, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af8945b9999e6d964885523337f00520
https://pubmed.ncbi.nlm.nih.gov/22424534