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المؤلفون: Robin Alec Fairhurst, James Neef, Brian Cox, Koremu Meja, Robert J. Turner, Paul Kirkham, David Beattie, Ryan West, Steven J. Charlton, Gillian Spooner, Helen Oakman, Zarin Brown, Lana Nanson, Roger J. Taylor, Hannah Woodward, John R. Fozard, Peter Gedeck, Andrew Brearley
المصدر: Bioorganic & Medicinal Chemistry Letters. 20:1219-1224
مصطلحات موضوعية: Purine, Agonist, Adenosine A2 Receptor Agonists, Receptor, Adenosine A2A, Stereochemistry, medicine.drug_class, Clinical Biochemistry, Carboxylic Acids, Drug Evaluation, Preclinical, Pharmaceutical Science, Adenosine A2A receptor, Carboxamide, CHO Cells, Biochemistry, Chemical synthesis, chemistry.chemical_compound, Cricetulus, Cricetinae, Amide, Drug Discovery, medicine, Animals, Humans, Molecular Biology, Aza Compounds, Chemistry, Organic Chemistry, Nucleosides, In vitro, Rats, Molecular Medicine, Pyrimidine Nucleotides, Nucleoside
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المؤلفون: Probir Chakravarty, Paul Kirkham, Irfan Rahman, Gillian Spooner, David Adenuga, Ian L. Megson, Isaac K. Sundar, Danielle Fletcher, Saravanan Rajendrasozhan, Paul A. Whittaker, Koremu Meja, John A. Marwick, Saibal K. Biswas
المصدر: Meja, K K, Rajendrasozhan, S, Adenuga, D, Biswas, S K, Sundar, I K, Spooner, G, Marwick, J A, Chakravarty, P, Fletcher, D, Whittaker, P, Megson, I L, Kirkham, P A & Rahman, I 2008, ' Curcumin restores corticosteroid function in monocytes exposed to oxidants by maintaining HDAC2 ', American Journal of Respiratory Cell and Molecular Biology, vol. 39, no. 3, pp. 312-23 . https://doi.org/10.1165/rcmb.2008-0012OC
مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Curcumin, Clinical Biochemistry, Histone Deacetylase 2, Cycloheximide, Pharmacology, medicine.disease_cause, Antioxidants, Histone Deacetylases, Monocytes, Pathogenesis, Pulmonary Disease, Chronic Obstructive, chemistry.chemical_compound, Adrenal Cortex Hormones, Smoke, Tobacco, MG132, medicine, Humans, Molecular Biology, Oligonucleotide Array Sequence Analysis, Protein Synthesis Inhibitors, Protein synthesis inhibitor, U937 cell, Histone deacetylase 2, Anti-Inflammatory Agents, Non-Steroidal, Smoking, Electron Spin Resonance Spectroscopy, U937 Cells, Articles, Cell Biology, Oxidants, Histone Deacetylase Inhibitors, Repressor Proteins, Oxidative Stress, chemistry, Immunology, Oxidative stress
وصف الملف: application/pdf
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المؤلفون: Claire Ffoulkes-Jones, Ronan Calvez, Gillian Spooner, Paul Kirkham
المصدر: Free Radical Biology and Medicine. 35:697-710
مصطلحات موضوعية: medicine.disease_cause, Biochemistry, Proinflammatory cytokine, Lipid peroxidation, Extracellular matrix, Mice, Pulmonary Disease, Chronic Obstructive, chemistry.chemical_compound, Smoke, Physiology (medical), Macrophages, Alveolar, Tobacco, Cell Adhesion, medicine, Animals, Humans, Macrophage, Acrolein, Receptors, Immunologic, Scavenger receptor, Receptor, Inflammation, Receptors, Scavenger, Chemotaxis, Smoking, Proteins, Cell biology, Respiratory burst, Oxidative Stress, Plants, Toxic, Pulmonary Emphysema, chemistry, Immunology, Lipid Peroxidation, Oxidative stress
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المؤلفون: Deborah Hynx, Claire Ffoulkes-Jones, Gaynor Elizabeth Pilgrim, Sarah Jeffers, Sandra Haberthuer, Elisabeth Schaebulin, John R. Fozard, Thomas H. Keller, Bernard Cuenoud, David Bentley, Katharine L. Turner, Andrew Nicholls, David Beattie, Morris Tweed, Lucy Barker, Sarah Craig, David Beer, Christoph Walker, Paul Kirkham, Rowan Stringer, David Farr, David Andrew Sandham, K D Butler, Colin Howes, Simon J. Watson, Lazzaro Mazzoni, Gillian Spooner, Louise Bidlake, Pamela Tranter, Janet Maas
المصدر: Bioorganicmedicinal chemistry. 12(19)
مصطلحات موضوعية: Stereochemistry, medicine.medical_treatment, Clinical Biochemistry, Pharmaceutical Science, Biological Availability, Thymus Gland, Pharmacology, Biochemistry, Chemical synthesis, Steroid, Cell Line, Structure-Activity Relationship, Glucocorticoid receptor, Receptors, Glucocorticoid, In vivo, Oral administration, Drug Discovery, Eosinophilia, medicine, Structure–activity relationship, Animals, Humans, Molecular Biology, Glucocorticoids, Chemistry, Tumor Necrosis Factor-alpha, Macrophages, Organic Chemistry, Esters, Organ Size, In vitro, Rats, Molecular Medicine, Androstenes, Glucocorticoid, medicine.drug, Protein Binding
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المؤلفون: Paul Kirkham, Adriano G. Rossi, Gillian Spooner, Irfan Rahman
المصدر: Biochemical and biophysical research communications. 318(1)
مصطلحات موضوعية: Collagen Type IV, Neutrophils, Phagocytosis, Biophysics, Inflammation, Apoptosis, Biochemistry, Extracellular matrix, medicine, Cell Adhesion, Macrophage, Humans, Receptor, Molecular Biology, Aldehydes, Extracellular Matrix Proteins, U937 cell, Chemistry, Macrophages, Smoking, Cell Biology, U937 Cells, In vitro, Cell biology, Extracellular Matrix, Fibronectins, Hyaluronan Receptors, Lipid Peroxidation, medicine.symptom
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المؤلفون: M P Smith, Geraldine Flynn, Gillian Spooner, Alexandra Aitken, Michael J. Mitchell, Yatin Patel, Rushika N Sumathipala, Kirti V Patel, Geoffrey F. Savidge, Salman Rahman
المصدر: Blood. 101(12)
مصطلحات موضوعية: Adult, Blood Platelets, Male, medicine.medical_specialty, Serotonin, DNA, Complementary, Epinephrine, Platelet Aggregation, Immunology, Biology, GTP-Binding Protein alpha Subunits, Gi-Go, Tritium, Biochemistry, Monocytes, Diglycerides, Thromboxane A2, chemistry.chemical_compound, Thrombin, Internal medicine, Thrombocytopathy, medicine, Cyclic AMP, Humans, Platelet, Carbon Radioisotopes, Diacylglycerol kinase, Arachidonic Acid, Cell Membrane, Colforsin, Cell Biology, Hematology, Sequence Analysis, DNA, Adenosine Diphosphate, Thromboxane B2, Adenosine diphosphate, Endocrinology, chemistry, Calcium, Blood Platelet Disorders, Collagen, Signal transduction, Dense granule, Phosphorus Radioisotopes, medicine.drug, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c57407df688e4a7f13fb5770e871ae1
https://pubmed.ncbi.nlm.nih.gov/12609843
