نتائج البحث - "Giovanni Zambrotta"

المساهمون: Fontana, D, Mauri, M, Renso, R, Docci, M, Crespiatico, I, Rost, L, Jang, M, Niro, A, D'Aliberti, D, Massimino, L, Bertagna, M, Zambrotta, G, Bossi, M, Citterio, S, Crescenzi, B, Fanelli, F, Cassina, V, Corti, R, Salerno, D, Nardo, L, Chinello, C, Mantegazza, F, Mecucci, C, Magni, F, Cavaletti, G, Bruheim, P, Rea, D, Larsen, S, Piazza, R, Gambacorti-Passerini, C

مصطلحات موضوعية: business.industry, Kinase, Somatic cell, Immunology, Mutator phenotype, Chronic myelomonocytic leukemia, Cell Biology, Hematology, medicine.disease, Biochemistry, medicine, Atypical chronic myeloid leukemia, Cancer research, Eosinophilia, Phosphorylation, Systemic mastocytosis, medicine.symptom, business, ETNK1, chronic myeloid leukemia

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::578629e64fd8f76dcfc678e902a04e43
https://hdl.handle.net/11380/1249547

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ETNK1 mutations induce a mutator phenotype that can be reverted with phosphoethanolamine

المساهمون: Fontana, D, Mauri, M, Renso, R, Docci, M, Crespiatico, I, Rost, L, Jang, M, Niro, A, D'Aliberti, D, Massimino, L, Bertagna, M, Zambrotta, G, Bossi, M, Citterio, S, Crescenzi, B, Fanelli, F, Cassina, V, Corti, R, Salerno, D, Nardo, L, Chinello, C, Mantegazza, F, Mecucci, C, Magni, F, Cavaletti, G, Bruheim, P, Rea, D, Larsen, S, Gambacorti-Passerini, C, Piazza, R

المصدر: Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Fontana, D, Mauri, M, Renso, R, Docci, M, Crespiatico, I, Røst, L M, Jang, M, Niro, A, D’aliberti, D, Massimino, L, Bertagna, M, Zambrotta, G, Bossi, M, Citterio, S, Crescenzi, B, Fanelli, F, Cassina, V, Corti, R, Salerno, D, Nardo, L, Chinello, C, Mantegazza, F, Mecucci, C, Magni, F, Cavaletti, G, Bruheim, P, Rea, D, Larsen, S, Gambacorti-passerini, C & Piazza, R 2020, ' ETNK1 mutations induce a mutator phenotype that can be reverted with phosphoethanolamine ', Nature Communications, vol. 11, no. 1, 5938 . https://doi.org/10.1038/s41467-020-19721-w

مصطلحات موضوعية: 0301 basic medicine, Myeloid, Cancer therapy, Somatic cell, Succinic Acid, General Physics and Astronomy, Cell Line, Cell Respiration, DNA Breaks, Electron Transport Complex II, Ethanolamines, Humans, Leukemia, Myeloid, Mitochondria, Mutation, Phenotype, Phosphotransferases (Alcohol Group Acceptor), Reactive Oxygen Species, Tigecycline, Mitochondrion, medicine.disease_cause, MITOCHONDRIAL, 0302 clinical medicine, PHOSPHATIDYLETHANOLAMINE, Ethanolamine, PHOSPHOMETABOLOME, Multidisciplinary, Leukemia, Hyperactivation, Molecular medicine, Chemistry, DNA Break, Cell biology, 030220 oncology & carcinogenesis, Phosphorylation, Reactive Oxygen Specie, Intracellular, Human, DNA damage, Science, HIGH-THROUGHPUT, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, medicine, TANDEM MASS-SPECTROMETRY, PATHWAYS, LEUKEMIA, LIPIDOME, REPAIR, Haematological cancer, General Chemistry, 030104 developmental biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9daa2965213b7e056a4bf82b15332df7
http://hdl.handle.net/10281/298474

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Abstract 3385: ETNK1 mutations promote ROS production and DNA damage through increased mitochondrial activity

المؤلفون: Giovanni Signore, Rocco Piazza, Mayla Bertagna, Carlo Gambacorti-Passerini, Mario Mauri, Stefania Citterio, Guido Cavaletti, Luca Massimino, Antonio Niro, Giovanni Zambrotta, Diletta Fontana, Vincenzo Piazza, Barbara Crescenzi, M Bossi, Delphine Rea, Cristina Mecucci

المصدر: Cancer Research. 78:3385-3385

مصطلحات موضوعية: chemistry.chemical_classification, Cancer Research, Mutation, Mutation rate, DNA damage, Somatic cell, Mitochondrion, Biology, medicine.disease_cause, medicine.disease, Molecular biology, Enzyme, Oncology, chemistry, medicine, Atypical chronic myeloid leukemia, Inner membrane

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::55fe636a0e9126f3d91ddb88bce39dc5
https://doi.org/10.1158/1538-7445.am2018-3385

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