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1دورية أكاديمية
المؤلفون: Erin Marie Kirwen, Tarun Batra, Chandrabose Karthikeyan, Girdhar Singh Deora, Vandana Rathore, Chaitanya Mulakayala, Naveen Mulakayala, Amy Catherine Nusbaum, Joel Chen, Haneen Amawi, Kyle McIntosh, Sahabjada, Neelam Shivnath, Deepak Chowarsia, Nisha Sharma, Md Arshad, Piyush Trivedi, Amit K. Tiwari
المصدر: Acta Pharmaceutica Sinica B, Vol 7, Iss 1, Pp 73-79 (2017)
مصطلحات موضوعية: 3H-Imidazo[4,5-b]pyri-dine, Cytotoxicity, MTT assay, COX inhibitors, Docking studies, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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المؤلفون: Julia Beveridge, Eric Tran, Girdhar Singh Deora, Fei Huang, Yuzhi Wang, Kieran Stockton, Ignacio Cotillo, Maria Santos Martinez Martinez, Silvia Gonzalez, Pablo Castañeda, Julian Sherman, Ana Rodriguez, Albane Kessler, Jonathan B. Baell
المصدر: Journal of Medicinal Chemistry. 66:1522-1542
مصطلحات موضوعية: Drug Discovery, Molecular Medicine
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المؤلفون: Girdhar Singh Deora, Aaron J. Oakley, Philip G. Board, Yuji Nakano, Jayme L. Dahlin, Padmaja Tummala, Jonathan B. Baell, Jessica M. Strasser, Yiyue Xie, Michael A. Walters, Melissa Rooke, Matthew E. Cuellar, Marco G. Casarotto
المصدر: Journal of Medicinal Chemistry. 63:2894-2914
مصطلحات موضوعية: Male, Cell, 01 natural sciences, law.invention, Mice, Structure-Activity Relationship, 03 medical and health sciences, Drug Development, law, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Enzyme Inhibitors, Glutathione Transferase, 030304 developmental biology, chemistry.chemical_classification, Sulfonamides, 0303 health sciences, Assay, Interleukin, 0104 chemical sciences, Molecular Docking Simulation, 010404 medicinal & biomolecular chemistry, Enzyme, medicine.anatomical_structure, chemistry, Biochemistry, Drug development, Recombinant DNA, Molecular Medicine, Cysteine
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المؤلفون: Amanda G. Eufrasio, Stephanie Russell, Girdhar Singh Deora, Amy J. Jones, Artur T. Cordeiro, Swapna Varghese, Vicky M. Avery, Raphaël Rahmani, Matthew J. Piggott, Lori Ferrins, Arthur Toynton, Julian Sherman, Melissa Sykes, Ana Rodriguez, Albane Kessler, Jonathan B. Baell
المصدر: ACS Med Chem Lett
مصطلحات موضوعية: Chagas disease, biology, 010405 organic chemistry, Organic Chemistry, Parasitemia, Trypanosoma brucei, Pyrazole, medicine.disease, biology.organism_classification, 01 natural sciences, Biochemistry, Virology, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry.chemical_compound, chemistry, parasitic diseases, Drug Discovery, medicine, African trypanosomiasis, Trypanosoma cruzi, IC50
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المؤلفون: Ban-Feng Ruan, Qing-Lei Guo, Qing-Shan Li, Lu-Zhi Li, Girdhar Singh Deora, Ben-Guo Zhou
المصدر: Current topics in medicinal chemistry. 22(7)
مصطلحات موضوعية: Oxadiazoles, Structure-Activity Relationship, Drug Discovery, Anti-Inflammatory Agents, General Medicine, Anti-Bacterial Agents
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15a1270ec32201b06d5adccb4c1d7911
https://pubmed.ncbi.nlm.nih.gov/35114924 -
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المؤلفون: Shaowei Zhang, Robert Schwarcz, Derren J. Heyes, Carlo Breda, Christopher David Edlin, Flaviano Giorgini, Nigel S. Scrutton, Girdhar Singh Deora, Colin Levy, Kevin D. Read, Marina Wright Muelas, Douglas B. Kell, David Leys, Benjamin P. Ross, Philip J. R. Day, Alex D Klausing, Stephen O’Hagan, Michiyo Sakuma
المصدر: Communications Biology, Vol 2, Iss 1, Pp 1-10 (2019)
Zhang, S, Sakuma, M, Deora, G S, Levy, C, Klausing, A, Breda, C, Read, K D, Ross, B P, Wright Muelas, M, Day, P, O'Hagan, S, Kell, D, Schwarcz, R, Leys, D, Heyes, D, Giorgini, F & Scrutton, N 2019, ' A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites ', Communications Biology . https://doi.org/10.1038/s42003-019-0520-5
Communications Biology
COMMUNICATIONS BIOLOGYمصطلحات موضوعية: Kynurenine pathway, Metabolite, Medicine (miscellaneous), Pharmacology, Neuroprotection, Article, General Biochemistry, Genetics and Molecular Biology, Pathogenesis, Mice, 03 medical and health sciences, chemistry.chemical_compound, Kynurenine 3-Monooxygenase, 0302 clinical medicine, Manchester Institute of Biotechnology, medicine, Animals, Neurodegeneration, Enzyme Inhibitors, lcsh:QH301-705.5, X-ray crystallography, 030304 developmental biology, 0303 health sciences, Drug discovery, business.industry, Brain, Neurodegenerative Diseases, Hydrogen Peroxide, Prodrug, medicine.disease, ResearchInstitutes_Networks_Beacons/manchester_institute_of_biotechnology, Chemical biology, 3. Good health, chemistry, lcsh:Biology (General), Blood-Brain Barrier, General Agricultural and Biological Sciences, business, 030217 neurology & neurosurgery, Kynurenine
وصف الملف: application/pdf
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المؤلفون: Kalicharan Sharma, Dharmarajan Sriram, Shakir Ali, Vagolu Siva Krishna, Omprakash Tanwar, M. S. Zaman, Mymoona Akhter, Girdhar Singh Deora, Mohammad Mumtaz Alam
المصدر: Bioorganic & Medicinal Chemistry. 27:1421-1429
مصطلحات موضوعية: Models, Molecular, Indoles, Tuberculosis, Stereochemistry, Clinical Biochemistry, Antitubercular Agents, Pharmaceutical Science, Microbial Sensitivity Tests, 01 natural sciences, Biochemistry, Structure-Activity Relationship, Drug Discovery, medicine, Humans, Structure–activity relationship, Enzyme Inhibitors, Molecular Biology, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Organic Chemistry, Mycobacterium tuberculosis, medicine.disease, In vitro, 0104 chemical sciences, Tetrahydrofolate Dehydrogenase, 010404 medicinal & biomolecular chemistry, Molecular Medicine, Antitubercular Agent
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المؤلفون: Yaodong Zhang, Zhen Zhang, Bing Shu, Qing Shan Li, Girdhar Singh Deora
المصدر: Current topics in medicinal chemistry. 20(28)
مصطلحات موضوعية: Drug, media_common.quotation_subject, Anti-Inflammatory Agents, Antineoplastic Agents, 01 natural sciences, Antiviral Agents, 03 medical and health sciences, chemistry.chemical_compound, Drug Discovery, medicine, Moiety, Humans, Thiazole, 030304 developmental biology, media_common, chemistry.chemical_classification, 0303 health sciences, 010405 organic chemistry, Rational design, Dabrafenib, Biological activity, General Medicine, Combinatorial chemistry, 0104 chemical sciences, Dasatinib, Thiazoles, chemistry, Heterocyclic compound, Drug Design, medicine.drug, Central Nervous System Agents
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d9efe4480604554d86dc2c43919f13d
https://pubmed.ncbi.nlm.nih.gov/32942975 -
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المؤلفون: Suresh Kumar Veliyath, Girdhar Singh Deora, Jared A. Miles, Samira Khabbazi, Gawain McColl, Marie-Odile Parat, Benjamin P. Ross, Srinivas Kantham, Stephen Chan, Satish N. Dighe
المصدر: ACS Chemical Neuroscience. 8:1901-1912
مصطلحات موضوعية: 0301 basic medicine, Honokiol, biology, Physiology, Chemistry, Amyloid beta, Cognitive Neuroscience, Cell Biology, General Medicine, Resveratrol, medicine.disease_cause, Biochemistry, Acetylcholinesterase, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, Toxicity, biology.protein, medicine, 030217 neurology & neurosurgery, Oxidative stress, Butyrylcholinesterase, Cholinesterase
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المؤلفون: Aarti Sevilimedu, Sharmistha Banerjee, Abdul Mohd Yaseen, Marina Rajadurai, E. Ramanjaneya Reddy, Girdhar Singh Deora, Arshad Rizvi
المصدر: ChemistrySelect. 2:557-561
مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Pyrene, Nanoparticle, General Chemistry, Self-assembly, Antimicrobial, Antibacterial activity, Selectivity, Fluorescence, Combinatorial chemistry, Uridine