المؤلفون: Looke, Thomas, Bent, Sandra, Franco-Mora, Ariana, Hedrick, Pamela, Newbern, Matthew, Tadros, Rafik, Pealer, Karen, Marcantonio, Edward, Vlassakov, Kamen, Buckley, Carolyn, Gorbatov, Svetlana, Gosnell, James, Steen, Talora, Vafai, Avery, Zeballos, Jose, Cardenas, Louis, Berry, Ashley, Getchell, John, Quercetti, Nicholas, Sessler, Daniel I., Ayad, Sabry, Hassan, Manal, Ali, Assad, Bajracharya, Gauasan, Billow, Damien, Bloomfield, Michael, Elliott, Kavita, Hampton, Robert, He, Linda, Honar, Hooman, Khoshknabi, Dilara, Kim, Daniel, Minko, Paul, Morris, Adam, Niazi, Azfar, Nutcharoen, Tara, Roberts, Jeffrey, Saha, Partha, Salih, Ahmed, Skolaris, Alexis, Stang, Taylor, Strimbu, Victor, Templeton, Jesse, Volio, Andrew, Wang, Jiayi, Bolkus, Kelly, DeAngelis, Matthew, Dodson, Gregory, Gerritsen, Jeffrey, McEniry, Brian, Mitrev, Ludmil, Kwofie, Kwesi, Bonazza, Flynn, Lloyd, Vera, Panek, Izabela, Dabiri, Jared, Chavez, Chris, Craig, Jason, Davidson, Todd, Dietrichs, Chad, Fleetwood, Cheryl, Foley, Mike, Getto, Chris, Hailes, Susie, Hermes, Sarah, Hooper, Andy, Koener, Greg, Kohls, Kate, Law, Leslie, Lipp, Adam, Losey, Allison, Nelson, William, Nieto, Mario, Rogers, Pam, Rutman, Steve, Scales, Garrett, Sebastian, Barbara, Stanciu, Tom, Lobel, Gregg, Giampiccolo, Michelle, Herman, Dara, Kaufman, Margit, Murphy, Bryan, Pau, Clara, Puzio, Thomas, Veselsky, Marlene, Stone, Trevor, Apostle, Kelly, Boyer, Dory, Fan, Brenda Chen, Lee, Susan, Lemke, Mike, Merchant, Richard, Moola, Farhad, Payne, Kyrsten, Perey, Bertrand, Viskontas, Darius, Poler, Mark, D'Antonio, Patricia, Sheppard, Richard, Abdullah, Amer, Fish-Fuhrmann, Jamie, Giska, Mark, Fidkowski, Christina, Guthrie, Trent, Hakeos, William, Hayes, Lillian, Hoegler, Joseph, Nowak, Katherine, Hymes, Robert, Beck, Jeffery, Cuff, Jaslynn, Gaski, Greg, Haaser, Sharon, Holzman, Michael, Malekzadeh, A. Stephen, Ramsey, Lolita, Schulman, Jeff, Schwartzbach, Cary, Sieber, Frederick, Azefor, Tangwan, Brown, Charles, Davani, Arman, Jaberi, Mahmood, Masear, Courtney, Sharma, Balram, Haider, Syed Basit, Chungu, Carolyn, Ebrahimi, Ali, Fikry, Karim, Gannon, Kerri, Marcantonio, Andrew, Pace, Meredith, Sanders, David, Clarke, Collin, Lawendy, Abdel, Schwartz, Gary, Garg, Mohit, Kim, Joseph, Marshall, Mitchell, Caurci, Juan, Commeh, Ekow, Cuevas, Randy, Cuff, Germaine, Franco, Lola, Furguiele, David, Giuca, Matthew, Allman, Melissa, Barzideh, Omid, Cossaro, James, D'Arduini, Armando, Farhi, Anita, Gould, Jason, Kafel, John, Patel, Anuj, Peller, Abraham, Reshef, Hadas, Safur, Mohammed, Toscano, Fiore, Tedore, Tiffany, Akerman, Michael, Brumberger, Eric, Clark, Sunday, Friedlander, Rachel, Jegarl, Anita, Lane, Joseph, Lyden, John P., Mehta, Nili, Murrell, Matthew T., Painter, Nathan, Ricci, William, Sbrollini, Kaitlyn, Sharma, Rahul, Steel, Peter A.D., Steinkamp, Michele, Weinberg, Roniel, Wellman, David Stephenson, Nader, Antoun, Fitzgerald, Paul, Ritz, Michaela, Papp, Steven, Bryson, Greg, Craig, Alexandra, Farhat, Cassandra, Gammon, Braden, Gofton, Wade, Harris, Nicole, Lalonde, Karl, Liew, Allan, Meulenkamp, Bradley, Sonnenburg, Kendra, Wai, Eugene, Wilkin, Geoffrey, Donegan, Derek, Dinh, Cassandra, Elkassabany, Nabil, Horan, Annamarie, Mehta, Samir, Troxell, Karen, Alderfer, Mary Ellen, Brannen, Jason, Cupitt, Christopher, Gerhart, Stacy, McLin, Renee, Sheidy, Julie, Yurick, Katherine, Carson, Jeffrey, Chen, Fei, Dragert, Karen, Kiss, Geza, Malveaux, Halina, McCloskey, Deborah, Mellender, Scott, Mungekar, Sagar S., Noveck, Helaine, Sagebien, Carlos, Perlman, Barry, Biby, Luat, McKelvy, Gail, Richards, Anna, Azim, Syed, Abola, Ramon, Ayala, Brittney, Halper, Darcy, Mavarez, Ana, Choi, Stephen, Awad, Imad, Flynn, Brendan, Henry, Patrick, Jenkinson, Richard, Kaustov, Lilia, Lappin, Elizabeth, McHardy, Paul, Singh, Amara, Hauck, Ellen, Donnelly, Joanne, Gonzalez, Meera, Haydel, Christopher, Livelsberger, Jon, Pazionis, Theresa, Slattery, Bridget, Vazquez-Trejo, Maritza, Schwenk, Eric, Baratta, Jaime, Deiling, Brittany, Deschamps, Laura, Glick, Michael, Katz, Daniel, Krieg, James, Lessin, Jennifer, Torjman, Marc, Chin, Ki Jinn, Jin, Rongyu, Salpeter, Mary Jane, Powell, Mark, Simmons, Jeffrey, Lawson, Prentiss, Kukreja, Promil, Graves, Shanna, Sturdivant, Adam, Bryant, Ayesha, Crump, Sandra Joyce, Dillane, Derek, Taylor, Michael, Verrier, Michelle, Applegate, Richard, Arias, Ana, Pineiro, Natasha, Uppington, Jeffrey, Wolinsky, Phillip, Sappenfield, Joshua, Gunnett, Amy, Hagen, Jennifer, Harris, Sara, Hollen, Kevin, Holloway, Brian, Horodyski, Mary Beth, Pogue, Trevor, Ramani, Ramachandran, Smith, Cameron, Woods, Anna, Warrick, Matthew, Flynn, Kelly, Mongan, Paul, Ranganath, Yatish, Fernholz, Sean, Ingersoll-Weng, Esperanza, Marian, Anil, Seering, Melinda, Sibenaller, Zita, Stout, Lori, Wagner, Allison, Walter, Alicia, Wong, Cynthia, Magaziner, Jay, Orwig, Denise, Brown, Trina, Dattilo, Jim, Ellenberg, Susan, Feng, Rui, Fleisher, Lee, Gaskins, Lakisha, Goud, Maithri, Helker, Chris, Mezenghie, Lydia, Montgomery, Brittany, Preston, Peter, Stephens, Alisa, Schwartz, J. Sanford, Tierney, Ann, Weber, Ramona, Chelly, Jacques, Goel, Shiv, Goncz, Wende, Kawabe, Touichi, Khetarpal, Sharad, King, Kevin, Kunkel, Frank, Luke, Charles, Monroe, Amy, Shick, Vladislav, Silipo, Anthony, Stehle, Caroline, Szabo, Katherine, Yennam, Sudhakar, Hoeft, Mark, Breidenstein, Max, Dominick, Timothy, Friend, Alexander, Mathews, Donald, Lennertz, Richard, Akere, Helen, Balweg, Tyler, Bo, Amber, Doro, Christopher, Goodspeed, David, Lang, Gerald, Parker, Maggie, Rettammel, Amy, Roth, Mary, Sanders, Robert, White, Marissa, Whiting, Paul, Allen, Brian, Baker, Tracie, Craven, Debra, McEvoy, Matt, Turnbo, Teresa, Kates, Stephen, Morgan, Melanie, Willoughby, Teresa, Weigel, Wade, Auyong, David, Fox, Ellie, Welsh, Tina, Jaffe, J. Douglas, Cusson, Bruce, Dobson, Sean, Edwards, Christopher, Harris, Lynette, Henshaw, Daryl, Johnson, Kathleen, McKinney, Glen, Miller, Scott, Reynolds, Jon, Turner, Jimmy, VanEenenaam, David, Weller, Robert, Akhtar, Shamsuddin, Blessing, Marcelle, Johnson, Chanel, Kampp, Michael, Kunze, Kimberly, Li, Jinlei, O'Connor, Mary, Treggiari, Miriam, Hruslinski, Jennifer, Menio, Diane A., Hymes, Robert A., Langlois, Christine, Gaskins, Lakisha J., Neuman, Mark D.

المصدر: In British Journal of Anaesthesia February 2021 126(2):395-403

المؤلفون: Gaulton, Timothy, Neuman, Mark, Lane-Fall, Meghan, Gaskins, Lakisha, Dattilo, James, El-Boghdadly, Kariem, Wong, Danny J.N., Ahmad, Imran, Johnstone, Craig, Gutstein, Howard B., Muehlschlegel, Jochen D., Hua, May, Fonseca, Laura, Mitrev, Ludmil, Low, Yinhui, Gupta, Dhanesh, Ayad, Sabry, Volio, Andrew, Salih, Ahmed, Kim, Daniel, Nutcharoen, Aratara, Skolaris, Alexis, Sherman, Marian, Giska, Mark, Nowak, Katherine, Chhina, Anoop, Guruswamy, Jayakar, Penning, Donald, Majewski, Michael, Nagrebetsky, Alexander, Houle, Timothy, Aziz, Michael F., Freed, Julie K., Lien, Cynthia A., Mihm, Fred, Desai, Pankaj M., Fahy, Brenda G., Davies, Laurie, Adair, Kelsey, Gunnett, Amy, Mhyre, Jill M., Sharawi, Nadir, Applegate, Richard, Brzenski, Alyssa, Lin, Michael Y., Olmos, Andrea, Chen, Catherine L., Gropper, Michael, Shochat, Guy, Hoefnagel, Amie, Ranganath, Yatish, Sibenellar, Zita, Colquhoun, Douglas A., Cloyd, Benjamin H., Healy, David W., Mathis, Michael R., Schechtman, Samuel A., Steadman, Joy, Stuart, Ami, Bott, Steven, Gerety, Lyle, Fisher, J. Matthew, Friend, Alexander F., Breidenstein, Max W., Domino, Karen B., Cervantes, Vanessa, Joffe, Aaron M., Dutton, Richard, Shanahan, Jessica, Leissner, Kay B., Jaffe, J. Doug, Strathman, Andrea, Khanna, Ashish K., Segal, B. Scott, Harris, Lynnette, Fowler, Jacob, Johnson, Kathleen, Hill, Shanna S., Murrell, Matthew T., Panzica, Peter, Mittnacht, Alexander, Abramowicz, Elizabeth, Wecksell, Matthew, Schonberger, Robert B., Li, Jinlei, Michel, Shannon, Treggiari, Miriam, Berstein, Steven, Dashevksy, Meir, Gaulton, Timothy G., Neuman, Mark D.

المصدر: In British Journal of Anaesthesia May 2021 126(5):e184-e186

المؤلفون: Fidkowski, Christina W., Hussain, Adnan, Younger, Joshua D., Giska, Mark A., McCurry, Cory, Loyd, Gary E.

المصدر: A&A Practice; Nov20222, Vol. 16 Issue 11, pe01643-e01643, 1p

المؤلفون: Neuman MD; Department of Anesthesiology and Critical Care, Perelman School of Medicine, and Center for Perioperative Outcomes Research and Transformation, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania (M.D.N., N.E., L.J.G.)., Feng R; Department of Biostatistics, Epidemiology, and Informatics, and Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania (R.F., S.S.E.)., Ellenberg SS; Department of Biostatistics, Epidemiology, and Informatics, and Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania (R.F., S.S.E.)., Sieber F; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland (F.S.)., Sessler DI; Department of Outcomes Research, Cleveland Clinic, Cleveland, Ohio (D.I.S., S. Ayad, M.H.)., Magaziner J; Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland (J.M.)., Elkassabany N; Department of Anesthesiology and Critical Care, Perelman School of Medicine, and Center for Perioperative Outcomes Research and Transformation, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania (M.D.N., N.E., L.J.G.)., Schwenk ES; Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania (E.S.S.)., Dillane D; Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton, Alberta, Canada (D. Dillane)., Marcantonio ER; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts (E.R.M.)., Menio D; Center for Advocacy for the Rights and Interests of the Elderly, Philadelphia, Pennsylvania (D.M.)., Ayad S; Department of Outcomes Research, Cleveland Clinic, Cleveland, Ohio (D.I.S., S. Ayad, M.H.)., Hassan M; Department of Outcomes Research, Cleveland Clinic, Cleveland, Ohio (D.I.S., S. Ayad, M.H.)., Stone T; Department of Orthopaedics, University of British Columbia, Vancouver, British Columbia, Canada (T.S.)., Papp S; Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa, Ontario, Canada (S.P.)., Donegan D; Department of Orthopaedic Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania (D. Donegan)., Marshall M; Department of Anesthesiology, New York University Langone Medical Center, New York, New York (M.M.)., Jaffe JD; Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, North Carolina (J.D.J.)., Luke C; Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania (C.L.)., Sharma B; Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington, Massachusetts (B.S.)., Azim S; Department of Anesthesiology, Stony Brook University, Stony Brook, New York (S. Azim)., Hymes R; Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church, Virginia (R.H.)., Chin KJ; Department of Anesthesiology and Pain Medicine, University of Toronto, Toronto, Ontario, Canada (K.C.)., Sheppard R; Department of Anesthesiology, Hartford Hospital, Hartford, Connecticut (R.S.)., Perlman B; Oregon Health and Science University, Portland, Oregon (B.P.)., Sappenfield J; Department of Anesthesiology, University of Florida College of Medicine, Gainesville, Florida (J.S.)., Hauck E; Department of Anesthesiology, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania (E.H.)., Hoeft MA; Department of Anesthesiology, University of Vermont Larner College of Medicine, Burlington, Vermont (M.A.H.)., Tierney A; Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania (A.T., T.B., J.D.)., Gaskins LJ; Department of Anesthesiology and Critical Care, Perelman School of Medicine, and Center for Perioperative Outcomes Research and Transformation, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania (M.D.N., N.E., L.J.G.)., Horan AD; Department of Anesthesiology and Critical Care, Perelman School of Medicine, and Department of Orthopaedic Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania (A.D.H.)., Brown T; Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania (A.T., T.B., J.D.)., Dattilo J; Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania (A.T., T.B., J.D.)., Carson JL; Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey (J.L.C.)., Looke T, Bent S, Franco-Mora A, Hedrick P, Newbern M, Tadros R, Pealer K, Vlassakov K, Buckley C, Gavin L, Gorbatov S, Gosnell J, Steen T, Vafai A, Zeballos J, Hruslinski J, Cardenas L, Berry A, Getchell J, Quercetti N, Bajracharya G, Billow D, Bloomfield M, Cuko E, Elyaderani MK, Hampton R, Honar H, Khoshknabi D, Kim D, Krahe D, Lew MM, Maheshwer CB, Niazi A, Saha P, Salih A, de Swart RJ, Volio A, Bolkus K, DeAngelis M, Dodson G, Gerritsen J, McEniry B, Mitrev L, Kwofie MK, Belliveau A, Bonazza F, Lloyd V, Panek I, Dabiri J, Chavez C, Craig J, Davidson T, Dietrichs C, Fleetwood C, Foley M, Getto C, Hailes S, Hermes S, Hooper A, Koener G, Kohls K, Law L, Lipp A, Losey A, Nelson W, Nieto M, Rogers P, Rutman S, Scales G, Sebastian B, Stanciu T, Lobel G, Giampiccolo M, Herman D, Kaufman M, Murphy B, Pau C, Puzio T, Veselsky M, Apostle K, Boyer D, Fan BC, Lee S, Lemke M, Merchant R, Moola F, Payne K, Perey B, Viskontas D, Poler M, D'Antonio P, O'Neill G, Abdullah A, Fish-Fuhrmann J, Giska M, Fidkowski C, Guthrie ST, Hakeos W, Hayes L, Hoegler J, Nowak K, Beck J, Cuff J, Gaski G, Haaser S, Holzman M, Malekzadeh AS, Ramsey L, Schulman J, Schwartzbach C, Azefor T, Davani A, Jaberi M, Masear C, Haider SB, Chungu C, Ebrahimi A, Fikry K, Marcantonio A, Shelvan A, Sanders D, Clarke C, Lawendy A, Schwartz G, Garg M, Kim J, Caruci J, Commeh E, Cuevas R, Cuff G, Franco L, Furgiuele D, Giuca M, Allman M, Barzideh O, Cossaro J, D'Arduini A, Farhi A, Gould J, Kafel J, Patel A, Peller A, Reshef H, Safur M, Toscano F, Tedore T, Akerman M, Brumberger E, Clark S, Friedlander R, Jegarl A, Lane J, Lyden JP, Mehta N, Murrell MT, Painter N, Ricci W, Sbrollini K, Sharma R, Steel PAD, Steinkamp M, Weinberg R, Wellman DS, Nader A, Fitzgerald P, Ritz M, Bryson G, Craig A, Farhat C, Gammon B, Gofton W, Harris N, Lalonde K, Liew A, Meulenkamp B, Sonnenburg K, Wai E, Wilkin G, Troxell K, Alderfer ME, Brannen J, Cupitt C, Gerhart S, McLin R, Sheidy J, Yurick K, Chen F, Dragert K, Kiss G, Malveaux H, McCloskey D, Mellender S, Mungekar SS, Noveck H, Sagebien C, Biby L, McKelvy G, Richards A, Abola R, Ayala B, Halper D, Mavarez A, Rizwan S, Choi S, Awad I, Flynn B, Henry P, Jenkinson R, Kaustov L, Lappin E, McHardy P, Singh A, Donnelly J, Gonzalez M, Haydel C, Livelsberger J, Pazionis T, Slattery B, Vazquez-Trejo M, Baratta J, Cirullo M, Deiling B, Deschamps L, Glick M, Katz D, Krieg J, Lessin J, Mojica J, Torjman M, Jin R, Salpeter MJ, Powell M, Simmons J, Lawson P, Kukreja P, Graves S, Sturdivant A, Bryant A, Crump SJ, Verrier M, Green J, Menon M, Applegate R, Arias A, Pineiro N, Uppington J, Wolinsky P, Gunnett A, Hagen J, Harris S, Hollen K, Holloway B, Horodyski MB, Pogue T, Ramani R, Smith C, Woods A, Warrick M, Flynn K, Mongan P, Ranganath Y, Fernholz S, Ingersoll-Weng E, Marian A, Seering M, Sibenaller Z, Stout L, Wagner A, Walter A, Wong C, Orwig D, Goud M, Helker C, Mezenghie L, Montgomery B, Preston P, Schwartz JS, Weber R, Fleisher LA, Mehta S, Stephens-Shields AJ, Dinh C, Chelly JE, Goel S, Goncz W, Kawabe T, Khetarpal S, Monroe A, Shick V, Breidenstein M, Dominick T, Friend A, Mathews D, Lennertz R, Sanders R, Akere H, Balweg T, Bo A, Doro C, Goodspeed D, Lang G, Parker M, Rettammel A, Roth M, White M, Whiting P, Allen BFS, Baker T, Craven D, McEvoy M, Turnbo T, Kates S, Morgan M, Willoughby T, Weigel W, Auyong D, Fox E, Welsh T, Cusson B, Dobson S, Edwards C, Harris L, Henshaw D, Johnson K, McKinney G, Miller S, Reynolds J, Segal BS, Turner J, VanEenenaam D, Weller R, Lei J, Treggiari M, Akhtar S, Blessing M, Johnson C, Kampp M, Kunze K, O'Connor M, Looke T, Tadros R, Vlassakov K, Cardenas L, Bolkus K, Mitrev L, Kwofie MK, Dabiri J, Lobel G, Poler M, Giska M, Sanders D, Schwartz G, Giuca M, Tedore T, Nader A, Bryson G, Troxell K, Kiss G, Choi S, Powell M, Applegate R, Warrick M, Ranganath Y, Chelly JE, Lennertz R, Sanders R, Allen BFS, Kates S, Weigel W, Li J, Wijeysundera DN, Kheterpal S, Moore RH, Smith AK, Tosi LL, Looke T, Mehta S, Fleisher L, Hruslinski J, Ramsey L, Langlois C, Mezenghie L, Montgomery B, Oduwole S, Rose T

مؤلفون مشاركون: REGAIN (Regional versus General Anesthesia for Promoting Independence after Hip Fracture) Investigators*, REGAIN (Regional versus General Anesthesia for Promoting Independence after Hip Fracture) Investigators

المصدر: Annals of internal medicine [Ann Intern Med] 2022 Jul; Vol. 175 (7), pp. 952-960. Date of Electronic Publication: 2022 Jun 14.

نوع المنشور: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American College of Physicians--American Society of Internal Medicine Country of Publication: United States NLM ID: 0372351 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1539-3704 (Electronic) Linking ISSN: 00034819 NLM ISO Abbreviation: Ann Intern Med Subsets: MEDLINE

مواضيع طبية MeSH: Anesthesia, Spinal*/adverse effects , Hip Fractures*/surgery, Aged ; Analgesics/therapeutic use ; Anesthesia, General/adverse effects ; Canada ; Female ; Humans ; Male ; Pain ; Pain, Postoperative/drug therapy ; Patient Satisfaction

المؤلفون: Fayed M; Anesthesiology and Perioperative Medicine, Henry Ford Health System, Detroit, USA., Giska MA; Anesthesiology, Perioperative Medicine and Pain Management, Henry Ford Health System, Detroit, USA., Shievitz RC; Anesthesia, Ascension Providence Hospital, Bingham Farms, USA., Attali A; Obstetrical Anesthesiology, Henry Ford Health System, Detroit, USA., Younger J; Obstetrical Anesthesiology, Henry Ford Health System, Detroit, USA.

المصدر: Cureus [Cureus] 2021 Dec 29; Vol. 13 (12), pp. e20802. Date of Electronic Publication: 2021 Dec 29 (Print Publication: 2021).

نوع المنشور: Case Reports

بيانات الدورية: Publisher: Cureus, Inc Country of Publication: United States NLM ID: 101596737 Publication Model: eCollection Cited Medium: Print ISSN: 2168-8184 (Print) Linking ISSN: 21688184 NLM ISO Abbreviation: Cureus Subsets: PubMed not MEDLINE

المؤلفون: Neuman MD; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Feng R; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Carson JL; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Gaskins LJ; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Dillane D; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Sessler DI; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Sieber F; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Magaziner J; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Marcantonio ER; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Mehta S; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Menio D; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Ayad S; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Stone T; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Papp S; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Schwenk ES; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Elkassabany N; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Marshall M; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Jaffe JD; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Luke C; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Sharma B; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Azim S; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Hymes RA; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Chin KJ; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Sheppard R; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Perlman B; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Sappenfield J; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Hauck E; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Hoeft MA; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Giska M; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Ranganath Y; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Tedore T; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Choi S; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Li J; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Kwofie MK; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Nader A; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Sanders RD; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Allen BFS; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Vlassakov K; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Kates S; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Fleisher LA; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Dattilo J; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Tierney A; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Stephens-Shields AJ; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.)., Ellenberg SS; From the Departments of Anesthesiology and Critical Care (M.D.N., L.J.G., N.E., L.A.F.), Biostatistics, Epidemiology, and Informatics (R.F., A.J.S.-S., S.S.E.), and Orthopedic Surgery (S.M.) and the Centers for Perioperative Outcomes Research and Transformation (M.D.N., L.J.G., N.E., L.A.F.) and Clinical Epidemiology and Biostatistics (R.F., J.D., A.T., A.J.S.-S., S.S.E.), University of Pennsylvania Perelman School of Medicine, the Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University (E.S.S.), the Center for Advocacy for the Rights and Interests of the Elderly (D.M.), and the Department of Anesthesiology, Lewis Katz School of Medicine at Temple University (E.H.), Philadelphia; the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.L.C.); the Department of Anesthesiology and Pain Medicine, University of Alberta Hospital, Edmonton (D.D.), the Department of Orthopaedics, University of British Columbia, Vancouver (T.S.), the Division of Orthopaedics, Ottawa Hospital Civic Campus, Ottawa (S.P.), the Department of Anesthesiology and Pain Medicine, University of Toronto (K.-J.C.), and the Department of Anesthesia, Sunnybrook Health Sciences Centre (S.C.), Toronto, and the Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax NS (M.K.K.) - all in Canada; the Department of Outcomes Research, Cleveland Clinic, Cleveland (D.I.S., S. Ayad); the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions (F.S.), and the Department of Epidemiology and Public Health, University of Maryland School of Medicine (J.M.) - both in Baltimore; the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School (E.R.M.), and the Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School (K.V.), Boston, and the Department of Anesthesiology, Lahey Hospital and Medical Center, Burlington (B.S.) - all in Massachusetts; the Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Health (M.M.), and the Department of Anesthesiology, New York-Presbyterian/Weill Cornell Medical Center (T.T.), New York, and the Department of Anesthesiology, Stony Brook University, Stony Brook (S. Azim) - all in New York; the Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC (J.D.J.); the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh (C.L.); the Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Falls Church (R.A.H.), and the Department of Orthopedic Surgery, Virginia Commonwealth University, Richmond (S.K.) - both in Virginia; the Department of Anesthesiology, Hartford Hospital, Hartford (R.S.), and the Department of Anesthesiology, Yale University School of Medicine, New Haven (J.L.) - both in Connecticut; Division of Hospital Medicine, Oregon Health and Science University, Portland (B.P.); the Department of Anesthesiology, University of Florida College of Medicine, Gainesville (J.S.); the Department of Anesthesiology, University of Vermont Larner School of Medicine, Burlington, VT (M.A.H.); the Department of Anesthesiology, Pain Management, and Perioperative Medicine, Henry Ford Health System, Detroit (M.G.); the Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City (Y.R.); the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago (A.N.); Specialty of Anaesthetics, University of Sydney, Sydney (R.D.S.); and the Division of Multispecialty Anesthesiology, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville (B.F.S.A.).

مؤلفون مشاركون: REGAIN Investigators

المصدر: The New England journal of medicine [N Engl J Med] 2021 Nov 25; Vol. 385 (22), pp. 2025-2035. Date of Electronic Publication: 2021 Oct 09.

نوع المنشور: Comparative Study; Journal Article; Multicenter Study; Pragmatic Clinical Trial; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Massachusetts Medical Society Country of Publication: United States NLM ID: 0255562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1533-4406 (Electronic) Linking ISSN: 00284793 NLM ISO Abbreviation: N Engl J Med Subsets: MEDLINE

مواضيع طبية MeSH: Anesthesia, General*/adverse effects , Anesthesia, Spinal*/adverse effects, Delirium/*etiology , Hip Fractures/*surgery, Aged ; Aged, 80 and over ; Delirium/epidemiology ; Female ; Hip Fractures/mortality ; Hip Fractures/physiopathology ; Humans ; Incidence ; Male ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Recovery of Function