نتائج البحث - "Giuseppina Sabatino"

المصدر: Organic process research & development 25 (2021): 2754–2771. doi:10.1021/acs.oprd.1c00368
info:cnr-pdr/source/autori:D'Ercole, Annunziata; Pacini, Lorenzo; Sabatino, Giuseppina; Zini, Matteo; Nuti, Francesca; Ribecai, Arianna; Paio, Alfredo; Rovero, Paolo; Papini, Anna Maria/titolo:An Optimized Safe Process from Bench to Pilot cGMP Production of API Eptifibatide Using a Multigram-Scale Microwave-Assisted Solid-Phase Peptide Synthesizer/doi:10.1021%2Facs.oprd.1c00368/rivista:Organic process research & development/anno:2021/pagina_da:2754/pagina_a:2771/intervallo_pagine:2754–2771/volume:25

مصطلحات موضوعية: chemistry.chemical_classification, Materials science, Chromatography, technology transfer, Organic Chemistry, multigram-scale microwave-assisted peptide synthesis, Peptide, generic peptide drug, Microwave assisted, peptide production scale-up, peptide production pilot plant, chemistry, Phase (matter), generic peptide drug, peptide production scale-up, multigram-scale microwave-assisted peptide synthesis, technology transfer, peptide production pilot plant, Eptifibatide, medicine, Physical and Theoretical Chemistry, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d29c2a766b49246c4ffd343dfd85a016
https://publications.cnr.it/doc/464122

9

An Optimized Scalable Fully Automated Solid-Phase Microwave-Assisted cGMP-Ready Process for the Preparation of Eptifibatide

المؤلفون: L. Pacini, Annunziata D’Ercole, Matteo Zini, Alfredo Paio, Paolo Rovero, Anna Maria Papini, Giuseppina Sabatino, Arianna Ribecai

المصدر: Organic process research & development (2021). doi:10.1021/acs.oprd.0c00490
info:cnr-pdr/source/autori:Papini, Anna Maria; Sabatino, Giuseppina; D'Ercole, Annunziata; Pacini, Lorenzo; Zini, Matteo; Ribecai, Arianna; Paio, Alfredo; Rovero, Paolo/titolo:An optimized scalable fully automated solid-phase microwave-assisted cGMP-ready process for the preparation of eptifibatide/doi:10.1021%2Facs.oprd.0c00490/rivista:Organic process research & development/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume

مصطلحات موضوعية: Materials science, Scale-up, Nanotechnology, active pharmaceutical ingredient, peptide, scale-up, oxidation, automated on-resin disulfide bond formation, off-resin disulfide bond formation, single reactor solid-phase synthesis, 010402 general chemistry, 01 natural sciences, Microwave assisted, chemistry.chemical_compound, Phase (matter), Oxidation, medicine, Peptide synthesis, Physical and Theoretical Chemistry, Active ingredient, 010405 organic chemistry, Organic Chemistry, Off-resin disulfide bond formation, 0104 chemical sciences, Fully automated, chemistry, Scientific method, Peptide, Single reactor solid-phase synthesis, Scalability, Eptifibatide, Active pharmaceutical ingredient, Automated on-resin disulfide bond formation, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87c4b0fe2aba17e3983bfb82d507cdb0
http://hdl.handle.net/2158/1219739

10

Detailed Insight into the Interaction of Bicyclic Somatostatin Analogue with Cu(II) Ions

المؤلفون: Weronika Witak, Anna Maria Papini, Aleksandra Marciniak, Giuseppina Sabatino, Justyna Brasuń

المصدر: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 8794, p 8794 (2020)
International journal of molecular sciences
21 (2020): 1–13. doi:10.3390/ijms21228794
info:cnr-pdr/source/autori:Marciniak, Aleksandra; Witak, Weronika; Sabatino, Giuseppina; Papini, Anna Maria; Brasu?, Justyna/titolo:Detailed insight into the interaction of bicyclic somatostatin analogue with Cu(II) ions/doi:10.3390%2Fijms21228794/rivista:International journal of molecular sciences (Print)/anno:2020/pagina_da:1/pagina_a:13/intervallo_pagine:1–13/volume:21
Volume 21
Issue 22

مصطلحات موضوعية: Stereochemistry, bicyclic peptide, Metal Binding Site, Peptide, Ligands, 01 natural sciences, Catalysis, Article, 030218 nuclear medicine & medical imaging, lcsh:Chemistry, Inorganic Chemistry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Coordination Complexes, copper(II) complexes, Imidazole, Amino Acid Sequence, Physical and Theoretical Chemistry, lcsh:QH301-705.5, Molecular Biology, Spectroscopy, chemistry.chemical_classification, Binding Sites, Bicyclic molecule, somatostatin analogues, 010405 organic chemistry, Magnetic circular dichroism, Chemistry, Ligand, Organic Chemistry, General Medicine, 0104 chemical sciences, Computer Science Applications, potentiometric titration, lcsh:Biology (General), lcsh:QD1-999, Intramolecular force, Radionuclide therapy, Somatostatin, Copper, Protein Binding, magnetic circular dichroism

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10130bfefd01dfc0cb42be29f6a476b4
https://pubmed.ncbi.nlm.nih.gov/33233719

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