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1دورية أكاديمية
المؤلفون: Yizhou Yin, Matthew G. Romei, Kannan Sankar, Lipika R. Pal, Kam Hon Hoi, Yanli Yang, Brandon Leonard, Gladys De Leon Boenig, Nikit Kumar, Marissa Matsumoto, Jian Payandeh, Seth F. Harris, John Moult, Greg A. Lazar
المصدر: Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 4952-4968 (2022)
مصطلحات موضوعية: Antibody, Cluster, Crystallography, Homotypic, Interface, Oligomer, Biotechnology, TP248.13-248.65
وصف الملف: electronic resource
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المؤلفون: Yizhou Yin, Matthew Romei, Kannan Sankar, Lipika R. Pal, Kam Hon Hoi, Yanli Yang, Brandon Leonard, Gladys De Leon Boenig, Nikit Kumar, Marissa Matsumoto, Jian Payandeh, Seth F. Harris, John Moult, Greg A. Lazar
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::88c034711e21402060f023147b15aa92
https://doi.org/10.1101/2022.04.06.487381 -
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المؤلفون: Yanli Yang, Sherry H. Yeh, Shravan Madireddi, Wadim L. Matochko, Chen Gu, Patricia Pacheco Sanchez, Mark Ultsch, Gladys De Leon Boenig, Seth F. Harris, Brandon Leonard, Suzie J. Scales, Jing W. Zhu, Erin Christensen, Julie Q. Hang, Randall J. Brezski, Scot Marsters, Avi Ashkenazi, Siddharth Sukumaran, Henry Chiu, Rafael Cubas, Jeong M. Kim, Greg A. Lazar
المصدر: mAbs
مصطلحات موضوعية: T-Lymphocytes, Immunology, Mice, Transgenic, OX40 Ligand, CHO Cells, Mice, SCID, Receptors, Fc, Agonism, 03 medical and health sciences, Jurkat Cells, Mice, 0302 clinical medicine, Cricetulus, CD28 Antigens, Report, antibody, Immunology and Allergy, Animals, Humans, OX40, DR5, Immunologic Capping, agonist, 030304 developmental biology, biepitopic, 0303 health sciences, Antibodies, Monoclonal, Receptors, TNF-Related Apoptosis-Inducing Ligand, 030220 oncology & carcinogenesis, TNFRSF, Signal Transduction
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المؤلفون: Maureen Beresini, Vickie Tsui, John S. Wai, F. Anthony Romero, Gladys de Leon Boenig, Patrick Cyr, Xiaoyu Zhu, Kevin X. Chen, Jiangpeng Liao, Edna F. Choo, Susan Kaufman, Fei Wang, Kwong Wah Lai, Caicai Zhu, Zhongguo Chen, Terry Crawford, Weichao Shen, Wenfeng Liu, Jeremy Murray, Yingjie Li, Sarah M. Bronner, Steven Magnuson, Justin Ly
المصدر: Bioorganic & Medicinal Chemistry Letters. 28:15-23
مصطلحات موضوعية: 0301 basic medicine, BRD4, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Cell Cycle Proteins, Molecular Dynamics Simulation, Crystallography, X-Ray, Biochemistry, Inhibitory Concentration 50, Mice, Structure-Activity Relationship, 03 medical and health sciences, Drug Discovery, Animals, Humans, p300-CBP Transcription Factors, Molecular Biology, Binding Sites, Bicyclic molecule, Chemistry, Biphenyl Compounds, Organic Chemistry, Nuclear Proteins, Hydrogen Bonding, Combinatorial chemistry, Protein Structure, Tertiary, Rats, Bromodomain, 030104 developmental biology, Cbp p300, Drug Design, Microsomes, Liver, Molecular Medicine, Half-Life, Transcription Factors
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المؤلفون: Yan Wu, Yvonne Chinn, Julie Q. Hang, Gladys de Leon Boenig, Søren Warming, Cary D. Austin, Yongmei Chen, Scott Stawicki, Cecilia Chiu, Mike Reichelt, Jeffrey Eastham-Anderson, Heather M. Moore, Daniel Lafkas, John B. Lowe, Christian W. Siebel, Jian Payandeh, Meron Roose-Girma, Meijuan Zhou, Wyne P. Lee, Xiumin Wu, Jackson G. Egen, Christian Siltanen, Amy L. Shelton
المصدر: Nature. 528:127-131
مصطلحات موضوعية: Male, JAG1, Cell signaling, Notch signaling pathway, Biology, Cell fate determination, Ligands, Antibodies, Mice, Animals, Homeostasis, Humans, Cell Lineage, Serrate-Jagged Proteins, Cilia, Progenitor cell, Lung, Mice, Inbred BALB C, Multidisciplinary, Cell Death, Receptors, Notch, Calcium-Binding Proteins, Transdifferentiation, Membrane Proteins, Asthma, Cell biology, Mice, Inbred C57BL, Disease Models, Animal, Cell Tracking, Cell Transdifferentiation, Immunology, Intercellular Signaling Peptides and Proteins, Respiratory epithelium, Female, Goblet Cells, Jagged-2 Protein, Cell Division, Jagged-1 Protein, Signal Transduction
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المؤلفون: Gladys de Leon Boenig, Alexis Rohou, Ryan Ferrao, Erin C. Dueber, Wayne J. Fairbrother, Elizabeth Helgason, Alberto Estevez, Michael J. Holliday
المصدر: The Journal of biological chemistry. 293(43)
مصطلحات موضوعية: 0301 basic medicine, Cell signaling, Crystallography, X-Ray, Biochemistry, p38 Mitogen-Activated Protein Kinases, Polymerization, 03 medical and health sciences, Protein Domains, Humans, Protein kinase A, Molecular Biology, Caspase, Innate immune system, biology, Chemistry, NF-kappa B, Cell Biology, B-Cell CLL-Lymphoma 10 Protein, BCL10, CARD Signaling Adaptor Proteins, Cytosol, Zinc, 030104 developmental biology, Structural biology, Protein Structure and Folding, biology.protein, Biophysics, Signal transduction, Protein Binding, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eee2181f756d887f83e79be962ad65dd
https://pubmed.ncbi.nlm.nih.gov/30206119 -
7دورية أكاديمية
المؤلفون: Daniel Lafkas, Amy Shelton, Cecilia Chiu, Gladys de Leon Boenig, Yongmei Chen, Scott S. Stawicki, Christian Siltanen, Mike Reichelt, Meijuan Zhou, Xiumin Wu, Jeffrey Eastham-Anderson, Heath
المصدر: Nature, Nature. 528(7580):127-131
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المؤلفون: Sarah G. Hymowitz, Alberto Gobbi, Gladys de Leon Boenig, Adam R. Johnson, Benjamin Fauber, Marya Liimatta, Celine Eidenschenk, Olivier Rene, Wenjun Ouyang, Peter Lockey, James R. Kiefer, Christine Everett, Heidi J.A. Wallweber, Brenda Burton, Harvey Wong, Maxine Norman
المصدر: ACS Medicinal Chemistry Letters. 6:276-281
مصطلحات موضوعية: Agonist, Gene isoform, medicine.drug_class, Stereochemistry, Chemistry, Organic Chemistry, Assay, Biochemistry, Nuclear receptor, Transcription (biology), RAR-related orphan receptor gamma, Drug Discovery, medicine, Inverse agonist, Selectivity
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المؤلفون: Jane L. Grogan, Ruina Li, Edna F. Choo, Sarah M. Bronner, Maureen Beresini, Jonathan Maher, Patrick Cyr, Yingjie Li, Thomas Hunsaker, Brian K. Albrecht, Colin Masui, Kevin R Clark, Yingqing Ran, Jeremy Murray, Terry Crawford, Xiaorong Liang, Fei Wang, F. Anthony Romero, Xiaocang Wei, Alexander M. Taylor, Georgia Hatzivassiliou, Kyle Clagg, Kwong Wah Lai, Karen E. Gascoigne, Le An, Steven Magnuson, Mark Merchant, John S. Wai, Zhongguo Chen, Jiangpeng Liao, Vickie Tsui, Emily Chan, Kevin X. Chen, Wenfeng Liu, Wei Huang, Dong Yu, Stefan G. Koenig, Susan Kaufman, Xiaoyu Zhu, Gladys de Leon Boenig, Justin Ly, Denise E. de Almeida Nagata, Bing-Yan Zhu
المصدر: Journal of medicinal chemistry. 60(22)
مصطلحات موضوعية: 0301 basic medicine, Male, Pyridines, Protein domain, Response element, Antineoplastic Agents, Proto-Oncogene Proteins c-myc, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Dogs, Protein Domains, In vivo, Drug Discovery, Structure–activity relationship, Animals, Humans, Cyclic adenosine monophosphate, IC50, Chemistry, Binding protein, Forkhead Transcription Factors, CREB-Binding Protein, Xenograft Model Antitumor Assays, Bromodomain, Macaca fascicularis, 030104 developmental biology, HEK293 Cells, Biochemistry, Molecular Medicine, Pyrazoles, RNA, Female
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المؤلفون: Harvey Wong, Celine Eidenschenk, Peter Lockey, Sarah G. Hymowitz, Christine Everett, Olivier Rene, Wenjun Ouyang, Maxine Norman, Marya Liimatta, Adam R. Johnson, Alberto Gobbi, Benjamin Fauber, Gladys de Leon Boenig, Brenda Burton
المصدر: Bioorganic & Medicinal Chemistry Letters. 23:6604-6609
مصطلحات موضوعية: Agonist, Drug Inverse Agonism, Hydrocarbons, Fluorinated, Propanols, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Molecular Dynamics Simulation, Crystallography, X-Ray, Biochemistry, Interferon-gamma, Structure-Activity Relationship, RAR-related orphan receptor gamma, Drug Discovery, medicine, Humans, Inverse agonist, Structure–activity relationship, Liver X receptor, Molecular Biology, Sulfonamides, Pregnane X receptor, Binding Sites, Chemistry, Interleukin-17, Organic Chemistry, Nuclear Receptor Subfamily 1, Group F, Member 3, Combinatorial chemistry, Protein Structure, Tertiary, Nuclear receptor, Drug Design, Leukocytes, Mononuclear, Molecular Medicine, lipids (amino acids, peptides, and proteins), Protein Binding