المؤلفون: Pitre Z; Seattle Children's Research Institute, Seattle, WA 98109, USA; Powerlight Technologies, Kent, WA 98032, USA., Seltzer T; Seattle Children's Research Institute, Seattle, WA 98109, USA., Kalthoff C; Seattle Children's Research Institute, Seattle, WA 98109, USA., Benitez-Cortez M; Seattle Children's Research Institute, Seattle, WA 98109, USA., Yee C; Seattle Children's Research Institute, Seattle, WA 98109, USA., Glennon EKK; Seattle Children's Research Institute, Seattle, WA 98109, USA., Primavera VI; Seattle Children's Research Institute, Seattle, WA 98109, USA., Kaushansky A; Seattle Children's Research Institute, Seattle, WA 98109, USA; Department of Pediatrics, University of Washington, Seattle, WA 98105, USA; Department of Global Health, University of Washington, Seattle, WA 98105, USA. Electronic address: alexis.kaushansky@seattlechildrens.org.

المصدر: STAR protocols [STAR Protoc] 2023 Dec 15; Vol. 4 (4), pp. 102621. Date of Electronic Publication: 2023 Sep 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101769501 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-1667 (Electronic) Linking ISSN: 26661667 NLM ISO Abbreviation: STAR Protoc Subsets: MEDLINE

مواضيع طبية MeSH: Anopheles*, Animals ; Mosquito Vectors

المؤلفون: Rodríguez-Hernández D; Department of Chemistry and Molecular Biology, University of Gothenburg; S-405 30, Gothenburg, Sweden.; Department of Chemistry, University of Bergen, Allegaten 41, NO-5007, Bergen, Norway., Vijayan K; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, 98109, USA.; School of Biology, Indian Institute of Science Education and Research, Thiruvananthapuram, Kerala, 695551, India., Zigweid R; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, 98109, USA.; Seattle Structural Genomics Center for Infectious Disease, Seattle, WA, 98109, USA., Fenwick MK; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, 98109, USA.; Seattle Structural Genomics Center for Infectious Disease, Seattle, WA, 98109, USA., Sankaran B; Molecular Biophysics and Integrated Bioimaging, Berkeley Center for Structural Biology, Advanced Light Source; Berkeley National Laboratory, Berkeley, CA, 94720, USA., Roobsoong W; Mahidol Vivax Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand., Sattabongkot J; Mahidol Vivax Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand., Glennon EKK; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, 98109, USA., Myler PJ; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, 98109, USA.; Seattle Structural Genomics Center for Infectious Disease, Seattle, WA, 98109, USA.; Department of Pediatrics, University of Washington, Seattle, WA, 98195, USA., Sunnerhagen P; Department of Chemistry and Molecular Biology, University of Gothenburg; S-405 30, Gothenburg, Sweden., Staker BL; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, 98109, USA.; Seattle Structural Genomics Center for Infectious Disease, Seattle, WA, 98109, USA., Kaushansky A; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, 98109, USA. Alexis.Kaushansky@seattlechildrens.org.; Department of Pediatrics, University of Washington, Seattle, WA, 98195, USA. Alexis.Kaushansky@seattlechildrens.org., Grøtli M; Department of Chemistry and Molecular Biology, University of Gothenburg; S-405 30, Gothenburg, Sweden. grotli@chem.gu.se.

المصدر: Nature communications [Nat Commun] 2023 Sep 05; Vol. 14 (1), pp. 5408. Date of Electronic Publication: 2023 Sep 05.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Malaria, Vivax* , Malaria, Falciparum*, Humans ; Animals ; Plasmodium vivax ; Schizonts ; Liver ; Acyltransferases

المؤلفون: Glennon EKK; Seattle Children's Research Institute, Center for Global Infectious Disease Research, Seattle, WA, United States., Tongogara T; Seattle Children's Research Institute, Center for Global Infectious Disease Research, Seattle, WA, United States.; Grinnell College, Grinnell, IA, United States., Primavera VI; Seattle Children's Research Institute, Center for Global Infectious Disease Research, Seattle, WA, United States., Reeder SM; Seattle Children's Research Institute, Center for Global Infectious Disease Research, Seattle, WA, United States., Wei L; Seattle Children's Research Institute, Center for Global Infectious Disease Research, Seattle, WA, United States., Kaushansky A; Seattle Children's Research Institute, Center for Global Infectious Disease Research, Seattle, WA, United States.; Department of Global Health, University of Washington, Seattle, WA, United States.; Department of Pediatrics, University of Washington, Seattle, WA, United States.; Brotman Baty Institute for Precision Medicine, Seattle, WA, United States.

المصدر: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2022 Jan 17; Vol. 11, pp. 804186. Date of Electronic Publication: 2022 Jan 17 (Print Publication: 2021).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 101585359 Publication Model: eCollection Cited Medium: Internet ISSN: 2235-2988 (Electronic) Linking ISSN: 22352988 NLM ISO Abbreviation: Front Cell Infect Microbiol Subsets: MEDLINE

مواضيع طبية MeSH: Malaria*/parasitology , Plasmodium*, Animals ; Humans ; Liver/parasitology ; Proteomics ; Sporozoites

المؤلفون: Dankwa S; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA., Dols MM; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA., Wei L; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA., Glennon EKK; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA., Kain HS; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA., Kaushansky A; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA; Department of Pediatrics, University of Washington, Seattle, WA 98105, USA. Electronic address: alexis.kaushansky@seattlechildrens.org., Smith JD; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA; Department of Pediatrics, University of Washington, Seattle, WA 98105, USA. Electronic address: joe.smith@seattlechildrens.org.

المصدر: Cell chemical biology [Cell Chem Biol] 2021 Dec 16; Vol. 28 (12), pp. 1679-1692.e4. Date of Electronic Publication: 2021 Jul 02.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Aniline Compounds/*pharmacology , Carbazoles/*pharmacology , Indole Alkaloids/*pharmacology , Nitriles/*pharmacology , Phosphotransferases/*antagonists & inhibitors , Protein Kinase Inhibitors/*pharmacology , Quinolines/*pharmacology, Aniline Compounds/chemistry ; Carbazoles/chemistry ; Cell Line ; Endothelial Cells/drug effects ; Endothelial Cells/metabolism ; Humans ; Indole Alkaloids/chemistry ; Nitriles/chemistry ; Phosphotransferases/genetics ; Phosphotransferases/metabolism ; Polypharmacology ; Protein Kinase Inhibitors/chemistry ; Quinolines/chemistry ; Signal Transduction/drug effects

المؤلفون: Vijayan K; Seattle Children's Research Institute, Seattle, Washington 98109, United States., Wei L; Seattle Children's Research Institute, Seattle, Washington 98109, United States., Glennon EKK; Seattle Children's Research Institute, Seattle, Washington 98109, United States., Mattocks C; Department of Global Health, University of Washington, Seattle, Washington 98195, United States., Bourgeois N; Seattle Children's Research Institute, Seattle, Washington 98109, United States.; Department of Global Health, University of Washington, Seattle, Washington 98195, United States., Staker B; Seattle Children's Research Institute, Seattle, Washington 98109, United States., Kaushansky A; Seattle Children's Research Institute, Seattle, Washington 98109, United States.; Department of Global Health, University of Washington, Seattle, Washington 98195, United States.; Department of Pediatrics, University of Washington, Seattle, Washington 98105, United States.; Brotman Baty Institute for Precision Medicine, Seattle, Washington 98195, United States.

المصدر: Chemical reviews [Chem Rev] 2021 Sep 08; Vol. 121 (17), pp. 10452-10468. Date of Electronic Publication: 2021 Jul 01.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Review

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 2985134R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6890 (Electronic) Linking ISSN: 00092665 NLM ISO Abbreviation: Chem Rev Subsets: MEDLINE

مواضيع طبية MeSH: Molecular Targeted Therapy*, Antimalarials/*pharmacology , Antimalarials/*therapeutic use , Host-Parasite Interactions/*drug effects , Malaria/*drug therapy, Humans ; Malaria/parasitology

المؤلفون: Vijayan K; Seattle Children's Research Institute, Seattle, WA, USA., Visweswaran GRR; Seattle Children's Research Institute, Seattle, WA, USA., Chandrasekaran R; Seattle Children's Research Institute, Seattle, WA, USA., Trakhimets O; Seattle Children's Research Institute, Seattle, WA, USA., Brown SL; Seattle Children's Research Institute, Seattle, WA, USA., Watson A; Seattle Children's Research Institute, Seattle, WA, USA., Zuck M; Seattle Children's Research Institute, Seattle, WA, USA., Dambrauskas N; Seattle Children's Research Institute, Seattle, WA, USA., Raappana A; Seattle Children's Research Institute, Seattle, WA, USA., Carbonetti S; Seattle Children's Research Institute, Seattle, WA, USA., Kelnhofer-Millevolte L; MSTP program, University of Washington, Seattle, WA, USA., Glennon EKK; Seattle Children's Research Institute, Seattle, WA, USA., Postiglione R; Seattle Children's Research Institute, Seattle, WA, USA., Sather DN; Seattle Children's Research Institute, Seattle, WA, USA; Department of Pediatrics, University of Washington, Seattle, WA, USA; Department of Global Health, University of Washington, Seattle, WA, USA. Electronic address: noah.sather@seattlechildrens.org., Kaushansky A; Seattle Children's Research Institute, Seattle, WA, USA; Department of Pediatrics, University of Washington, Seattle, WA, USA; Department of Global Health, University of Washington, Seattle, WA, USA; Brotman Baty Research Institute, Seattle, WA, USA; Institute for Stem Cell and Regenerative Medicine, Seattle, WA, USA. Electronic address: alexis.kaushansky@seattlechildrens.org.

المصدر: Cell reports [Cell Rep] 2021 Aug 03; Vol. 36 (5), pp. 109489.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Immunity, Humoral* , Life Cycle Stages*, Antibodies, Neutralizing/*immunology , Antibodies, Protozoan/*immunology , Liver/*parasitology , Plasmodium yoelii/*growth & development , Plasmodium yoelii/*immunology, Animals ; Antibodies, Monoclonal/immunology ; Antibodies, Monoclonal/isolation & purification ; Cell Line ; Epitopes/immunology ; Female ; Kinetics ; Malaria Vaccines/immunology ; Mice, Inbred BALB C ; Models, Biological ; Protein Binding ; Protein Domains ; Protozoan Proteins/chemistry ; Protozoan Proteins/immunology ; Sporozoites/immunology ; Vaccines, Synthetic/immunology ; Mice

المؤلفون: Kain HS; Center for Infectious Disease Research, Seattle Biomedical Research Institute, Seattle, WA, USA., Glennon EKK; Center for Infectious Disease Research, Seattle Biomedical Research Institute, Seattle, WA, USA.; Seattle Children's Research Institute, Seattle, WA, USA., Vijayan K; Center for Infectious Disease Research, Seattle Biomedical Research Institute, Seattle, WA, USA.; Seattle Children's Research Institute, Seattle, WA, USA., Arang N; Center for Infectious Disease Research, Seattle Biomedical Research Institute, Seattle, WA, USA.; Department of Biomedical Sciences, University of California, San Diego, La Jolla, CA, USA., Douglass AN; Center for Infectious Disease Research, Seattle Biomedical Research Institute, Seattle, WA, USA.; Pathobiology Program, University of Washington, Seattle, WA, USA., Fortin CL; Departments of Bioengineering & Pathology, Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA., Zuck M; Center for Infectious Disease Research, Seattle Biomedical Research Institute, Seattle, WA, USA.; Seattle Children's Research Institute, Seattle, WA, USA., Lewis AJ; Center for Infectious Disease Research, Seattle Biomedical Research Institute, Seattle, WA, USA., Whiteside SL; Center for Infectious Disease Research, Seattle Biomedical Research Institute, Seattle, WA, USA.; Seattle Children's Research Institute, Seattle, WA, USA., Dudgeon DR; Center for Infectious Disease Research, Seattle Biomedical Research Institute, Seattle, WA, USA., Johnson JS; Center for Infectious Disease Research, Seattle Biomedical Research Institute, Seattle, WA, USA.; Department of Biochemistry, University of Utah, Salt Lake City, UT, USA., Aderem A; Center for Infectious Disease Research, Seattle Biomedical Research Institute, Seattle, WA, USA.; Seattle Children's Research Institute, Seattle, WA, USA.; Department of Immunology, University of Washington, Seattle, WA, USA., Stevens KR; Departments of Bioengineering & Pathology, Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA., Kaushansky A; Center for Infectious Disease Research, Seattle Biomedical Research Institute, Seattle, WA, USA. alexis.kaushansky@seattlechildrens.org.; Seattle Children's Research Institute, Seattle, WA, USA. alexis.kaushansky@seattlechildrens.org.; Department of Global Health, University of Washington, Seattle, WA, USA. alexis.kaushansky@seattlechildrens.org.

المصدر: Cell death and differentiation [Cell Death Differ] 2020 Jan; Vol. 27 (1), pp. 44-54. Date of Electronic Publication: 2019 May 07.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9437445 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5403 (Electronic) Linking ISSN: 13509047 NLM ISO Abbreviation: Cell Death Differ Subsets: MEDLINE

مواضيع طبية MeSH: Lipid Peroxidation*, Amino Acid Transport System y+/*metabolism , Liver Diseases/*metabolism , Liver Diseases/*parasitology , Malaria/*metabolism, Amino Acid Transport System y+/antagonists & inhibitors ; Animals ; Cell Line ; Cells, Cultured ; Ferroptosis ; Mice, Inbred C57BL ; Mice, Knockout ; NADPH Oxidase 1/genetics ; Phospholipid Hydroperoxide Glutathione Peroxidase/antagonists & inhibitors ; Phospholipid Hydroperoxide Glutathione Peroxidase/metabolism ; Reactive Oxygen Species/metabolism ; Receptors, Transferrin/metabolism ; Signal Transduction ; Tumor Suppressor Protein p53/metabolism

المؤلفون: Vijayan K; Center for Global Infectious Disease Research, Seattle Children's Research Institute, 307 Westlake Avenue, N. Suite 500, Seattle, WA 98109, USA., Cestari I; Center for Global Infectious Disease Research, Seattle Children's Research Institute, 307 Westlake Avenue, N. Suite 500, Seattle, WA 98109, USA; Institute of Parasitology, McGill University, Ste Anne de Bellevue, QC H9X 3V9, Canada., Mast FD; Center for Global Infectious Disease Research, Seattle Children's Research Institute, 307 Westlake Avenue, N. Suite 500, Seattle, WA 98109, USA; Institute for Systems Biology, 401 Terry Avenue, N, Seattle, WA 98109, USA., Glennon EKK; Center for Global Infectious Disease Research, Seattle Children's Research Institute, 307 Westlake Avenue, N. Suite 500, Seattle, WA 98109, USA., McDermott SM; Center for Global Infectious Disease Research, Seattle Children's Research Institute, 307 Westlake Avenue, N. Suite 500, Seattle, WA 98109, USA., Kain HS; Center for Global Infectious Disease Research, Seattle Children's Research Institute, 307 Westlake Avenue, N. Suite 500, Seattle, WA 98109, USA., Brokaw AM; Department of Global Health, University of Washington, Harris Hydraulics Laboratory Box 357965, Seattle, WA 98195-7965, USA., Aitchison JD; Center for Global Infectious Disease Research, Seattle Children's Research Institute, 307 Westlake Avenue, N. Suite 500, Seattle, WA 98109, USA; Institute for Systems Biology, 401 Terry Avenue, N, Seattle, WA 98109, USA., Stuart K; Center for Global Infectious Disease Research, Seattle Children's Research Institute, 307 Westlake Avenue, N. Suite 500, Seattle, WA 98109, USA; Department of Global Health, University of Washington, Harris Hydraulics Laboratory Box 357965, Seattle, WA 98195-7965, USA., Kaushansky A; Center for Global Infectious Disease Research, Seattle Children's Research Institute, 307 Westlake Avenue, N. Suite 500, Seattle, WA 98109, USA; Department of Global Health, University of Washington, Harris Hydraulics Laboratory Box 357965, Seattle, WA 98195-7965, USA. Electronic address: alexis.kaushansky@seattlechildrens.org.

المصدر: IScience [iScience] 2019 Nov 22; Vol. 21, pp. 603-611. Date of Electronic Publication: 2019 Oct 31.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE

المؤلفون: Glennon EKK; Center for Infectious Disease Research, Seattle, WA 98109, USA; Seattle Children's Research Institute, Seattle, WA 98109, USA; Department of Global Health, University of Washington, Seattle, WA 98109, USA., Austin LS; Center for Infectious Disease Research, Seattle, WA 98109, USA., Arang N; Center for Infectious Disease Research, Seattle, WA 98109, USA., Kain HS; Center for Infectious Disease Research, Seattle, WA 98109, USA., Mast FD; Center for Infectious Disease Research, Seattle, WA 98109, USA; Seattle Children's Research Institute, Seattle, WA 98109, USA; Institute for Systems Biology, Seattle, WA 98109, USA., Vijayan K; Center for Infectious Disease Research, Seattle, WA 98109, USA; Seattle Children's Research Institute, Seattle, WA 98109, USA., Aitchison JD; Center for Infectious Disease Research, Seattle, WA 98109, USA; Seattle Children's Research Institute, Seattle, WA 98109, USA; Institute for Systems Biology, Seattle, WA 98109, USA., Kappe SHI; Center for Infectious Disease Research, Seattle, WA 98109, USA; Seattle Children's Research Institute, Seattle, WA 98109, USA; Department of Global Health, University of Washington, Seattle, WA 98109, USA., Kaushansky A; Center for Infectious Disease Research, Seattle, WA 98109, USA; Seattle Children's Research Institute, Seattle, WA 98109, USA; Department of Global Health, University of Washington, Seattle, WA 98109, USA. Electronic address: alexis.kaushansky@seattlechildrens.org.

المصدر: Cell reports [Cell Rep] 2019 Mar 19; Vol. 26 (12), pp. 3391-3399.e4.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Hepatocytes/*metabolism , Malaria/*metabolism , Plasmodium yoelii/*metabolism , Ribosomal Protein S6/*metabolism, Animals ; Cell Line ; Hepatocytes/parasitology ; Hepatocytes/pathology ; Humans ; Malaria/pathology ; Mice ; Mice, Inbred BALB C ; Phosphorylation ; Toxoplasma/metabolism ; Toxoplasmosis/metabolism ; Toxoplasmosis/pathology

المؤلفون: Glennon EKK; Center for Infectious Disease Research, 307 Westlake Ave N Suite 500, Seattle, WA 98109, USA; Department of Global Health, University of Washington, Harris Hydraulics Laboratory, Box 357965, Seattle, WA 98195, USA; These authors made an equal contribution., Dankwa S; Center for Infectious Disease Research, 307 Westlake Ave N Suite 500, Seattle, WA 98109, USA; These authors made an equal contribution., Smith JD; Center for Infectious Disease Research, 307 Westlake Ave N Suite 500, Seattle, WA 98109, USA; Department of Global Health, University of Washington, Harris Hydraulics Laboratory, Box 357965, Seattle, WA 98195, USA., Kaushansky A; Center for Infectious Disease Research, 307 Westlake Ave N Suite 500, Seattle, WA 98109, USA; Department of Global Health, University of Washington, Harris Hydraulics Laboratory, Box 357965, Seattle, WA 98195, USA. Electronic address: alexis.kaushansky@cidresearch.org.

المصدر: Trends in parasitology [Trends Parasitol] 2018 Oct; Vol. 34 (10), pp. 843-860. Date of Electronic Publication: 2018 Aug 16.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Review

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 100966034 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-5007 (Electronic) Linking ISSN: 14714922 NLM ISO Abbreviation: Trends Parasitol Subsets: MEDLINE

مواضيع طبية MeSH: Drug Delivery Systems*, Antimalarials/*immunology, Antimalarials/pharmacology ; Host-Parasite Interactions/drug effects ; Humans ; Immunologic Factors/pharmacology