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المؤلفون: Anna Billeschou Bomholt, Christian Dall Johansen, Sasha A. S. Kjeldsen, Katrine D. Galsgaard, Jens Bager Christensen, Marie Winther-Sørensen, Reza Serizawa, Mads Hornum, Esteban Porrini, Jens Pedersen, Cathrine Ørskov, Lise L. Gluud, Charlotte Mehlin Sørensen, Jens J. Holst, Reidar Albrechtsen, Nicolai J. Wewer Albrechtsen
المصدر: Bomholt, A B, Johansen, C D, Christensen, J B, Kjeldsen, S A S, Galsgaard, K D, Winther-Sørensen, M, Serizawa, R, Hornum, M, Porrini, E, Pedersen, J, Ørskov, C, Gluud, L L, Sørensen, C M, Holst, J J, Albrechtsen, R & Wewer Albrechtsen, N J 2022, ' Evaluation of commercially available glucagon receptor antibodies and glucagon receptor expression ', Communications Biology, vol. 5, no. 1, 1278 . https://doi.org/10.1038/s42003-022-04242-7
مصطلحات موضوعية: Liver/metabolism, Liver, Receptors, Glucagon, Medicine (miscellaneous), Gene Expression, Receptors, Glucagon/genetics, General Agricultural and Biological Sciences, Glucagon, General Biochemistry, Genetics and Molecular Biology, Antibodies, Antibodies/metabolism
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URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deed2a2ff720b0aae1000d5305e0e5e5
https://curis.ku.dk/ws/files/327932782/Evaluation_of_commercially.pdf -
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المؤلفون: François Pattou, Frans Schuit, Thierry Berney, Philippe A. Halban, Jan A. Ehses, Roel Quintens, Marc Y. Donath, Geert A. Martens, Daniel Pipeleers, Julie Kerr-Conte, Helga Ellingsgaard, Eva Hammar, Leentje Van Lommel
المساهمون: Medical Biochemistry, Department of Bio-engineering Sciences, Pathologic Biochemistry and Physiology, University of Zurich
المصدر: Proceedings of the National Academy of Sciences, Vol. 105, No 35 (2008) pp. 13163-8
مصطلحات موضوعية: Protein Precursors/genetics/metabolism, RNA, Messenger/genetics, Male, Endocrinology, Diabetes and Metabolism, Interleukin-6/metabolism, 10265 Clinic for Endocrinology and Diabetology, Gene Expression Regulation/drug effects, Apoptosis, Type 2 diabetes, Alpha cell, Cell Proliferation/drug effects, Mice, Insulin-Secreting Cells/cytology, Receptors, Interleukin-6/genetics, Glucagon/genetics/metabolism, Insulin-Secreting Cells, ddc:576.5, Phosphorylation, Insulin-Secreting Cells/cytology/drug effects, Mice, Knockout, Glucose tolerance test, Multidisciplinary, geography.geographical_feature_category, medicine.diagnostic_test, Receptors, Interleukin-6/genetics/metabolism, Glucagon secretion, Phosphorylation/drug effects, Biological Sciences, Islet, medicine.anatomical_structure, 10076 Center for Integrative Human Physiology, Pancreas, STAT3 Transcription Factor, medicine.medical_specialty, RNA, Messenger/genetics/metabolism, 610 Medicine & health, Biology, Glucagon, Glucagon-Secreting Cells/cytology, Internal medicine, Diabetes mellitus, medicine, Animals, Humans, Feeding Behavior/drug effects, Glucagon/genetics, RNA, Messenger, Protein Precursors, Rats, Wistar, Cell Proliferation, 1000 Multidisciplinary, geography, Interleukin-6, Apoptosis/drug effects, Protein Precursors/genetics, Feeding Behavior, Glucose Tolerance Test, medicine.disease, Dietary Fats, Receptors, Interleukin-6, Rats, Mice, Inbred C57BL, Dietary Fats/pharmacology, Endocrinology, Gene Expression Regulation, STAT3 Transcription Factor/metabolism, Glucagon-Secreting Cells, 570 Life sciences, biology, Glucagon-Secreting Cells/cytology/drug effects
وصف الملف: 7323_Interleukin-6_regulates2008V.pdf - application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2407c6316e9553ef3cbaa0de2d907ab8
https://doi.org/10.1073/pnas.0801059105 -
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المؤلفون: Gao, Ru, Ustinov, Jarkko, Pulkkinen, Mari-Anne, Lundin, Karolina, Korsgren, Olle, Otonkoski, Timo
المصدر: Diabetes. 52(8):2007-15
مصطلحات موضوعية: Adult, Animals, Biocompatible Materials, Cell Differentiation/physiology, Cell Division/physiology, Cells, Cultured, Collagen, Drug Combinations, Epithelial Cells/chemistry/cytology, Gene Expression/physiology, Glucagon/genetics, Humans, Insulin/genetics/metabolism, Intermediate Filament Proteins/analysis, Islets of Langerhans/chemistry/*cytology/metabolism, Islets of Langerhans Transplantation, Keratin/analysis, Laminin, Mice, Nude, Nerve Tissue Proteins, Proteoglycans, Research Support, Non-U.S. Gov't, Stem Cells/chemistry/*cytology
وصف الملف: print
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المؤلفون: Philippe A. Halban, Beate Ritz-Laser, Benoit R. Gauthier, Jacques Philippe, Didier Trono, Aline Mamin, Anne Estreicher, Frédéric Ris, Thierry Brun, Patrick Salmon
المصدر: Diabetologia, Vol. 46, No 6 (2003) pp. 810-821
مصطلحات موضوعية: endocrine system, Transcription, Genetic, endocrine system diseases, Endocrinology, Diabetes and Metabolism, Genetic Vectors, Molecular Sequence Data, Glucagonoma, Biology, Transfection, digestive system, Glucagon, Alpha cell, Cell Line, Islets of Langerhans, Cricetinae, Internal Medicine, medicine, Animals, Humans, Insulin, Northern blot, Homeodomain Proteins/genetics/metabolism, Transcription factor, Trans-Activators/ genetics/metabolism, Glucagon-like peptide 1 receptor, ddc:616, Homeodomain Proteins, Transcription, Genetic/ genetics, Binding Sites, Base Sequence, Mesocricetus, Insulin/genetics, medicine.disease, Molecular biology, Islets of Langerhans/physiology, Glucagon/ genetics, Oligodeoxyribonucleotides, Organ Specificity, Trans-Activators, PDX1, Ectopic expression
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المؤلفون: Jean-Louis Junien, Richard B. White, D. Michael Evans, Robert Haigh, Beatrice Sudre, Pierre Broqua, Michel L. Aubert, Doreen Mary Ashworth
المصدر: Diabetes, Vol. 51, No 5 (2002) pp. 1461-9
مصطلحات موضوعية: Blood Glucose, Male, Pyrrolidines, Eating/drug effects, Endocrinology, Diabetes and Metabolism, Gene Expression, Type 2 diabetes, Fatty Acids, Nonesterified, Weight Gain, Impaired glucose tolerance, Eating, Glucagon-Like Peptide 1, Oral administration, Receptors, Glucagon, Insulin, Receptors, Glucagon/genetics, Gene Expression/physiology, Pancreas/physiology, Glucose tolerance test, ddc:618, medicine.diagnostic_test, Nitriles/chemistry/pharmacology, Fatty Acids, Nonesterified/blood, Glucagon-like peptide-1, Triglycerides/blood, Glucagon/blood, Diabetes Mellitus/blood/drug therapy/enzymology, medicine.medical_specialty, Dipeptidyl Peptidase 4, Diabetes Mellitus, Type 2/blood/drug therapy, Drinking, Glucagon-Like Peptide-1 Receptor, Dipeptidyl peptidase, Diabetes mellitus, Internal medicine, Nitriles, Diabetes Mellitus, Internal Medicine, medicine, Animals, Humans, Protease Inhibitors, Obesity, Protein Precursors, Pancreas, Triglycerides, Dipeptidyl Peptidase 4/blood, Protein Precursors/blood, Weight Gain/drug effects, business.industry, Drinking/drug effects, Hypertriglyceridemia, Glucose Tolerance Test, Glucagon, medicine.disease, Pyrrolidines/chemistry/pharmacology, Peptide Fragments, Rats, Rats, Zucker, Endocrinology, Diabetes Mellitus, Type 2, Protease Inhibitors/chemistry/pharmacology, Insulin/blood, Peptide Fragments/blood, business
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المؤلفون: Pedro Muniesa, Pedro Luis Herrera, Lelio Orci, Bernadette Mermillod, Francesca Sanvito, Jacques Philippe, Jean-Dominique Vassalli, Joaquin Huarte, Romain Zufferey, Anthony Nichols
المصدر: Proceedings of the National Academy of Sciences, Vol. 91, No 26 (1994) pp. 12999-13003
مصطلحات موضوعية: endocrine system, medicine.medical_specialty, Mice, Transgenic, Enteroendocrine cell, Biology, Pancreatic Polypeptide, Glucagon, Pancreatic Polypeptide/genetics, Islets of Langerhans, Mice, Paracrine signalling, Internal medicine, medicine, Animals, Insulin, Pancreatic polypeptide, Diphtheria Toxin, Glucagon/genetics, Promoter Regions, Genetic, ddc:616, Somatostatin/metabolism, Delta cell, geography, Multidisciplinary, geography.geographical_feature_category, Cell Death, Insulin/genetics, Islet, Cell biology, medicine.anatomical_structure, Endocrinology, Diphtheria Toxin/administration & dosage, Somatostatin, Pancreas, RFX6, Islets of Langerhans/ cytology/embryology, Research Article
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5d7d6156bca384b7dd61f6b8c9d2ad4
https://doi.org/10.1073/pnas.91.26.12999 -
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المؤلفون: Kenneth S. Polonsky, Judy L. Shih, Dan Kawamori, Eric L. Ford, Owen P. McGuinness, Pedro Luis Herrera, Chong Wee Liew, Rohit N. Kulkarni, Jiang Hu, Amarnath J. Kurpad
المصدر: Cell Metabolism, Vol. 9, No 4 (2009) pp. 350-361
مصطلحات موضوعية: Physiology, medicine.medical_treatment, HUMDISEASE, Gene Expression Regulation/drug effects, Alpha cell, Mice, 0302 clinical medicine, Insulin-Secreting Cells, Glucose homeostasis, Insulin, ddc:576.5, Organ Specificity/drug effects, Mice, Knockout, 0303 health sciences, biology, Insulin-Secreting Cells/drug effects/metabolism/pathology, Glucagon secretion, Fasting, Organ Size, Hyperinsulinism/complications/metabolism, Organ Specificity, Insulin/genetics/*metabolism, Beta cell, hormones, hormone substitutes, and hormone antagonists, Glucagon/genetics/*secretion, Signal Transduction, endocrine system, medicine.medical_specialty, 030209 endocrinology & metabolism, Arginine, Glucagon, Streptozocin, Diabetes Mellitus, Experimental, 03 medical and health sciences, Internal medicine, Hyperinsulinism, Glucagon-Secreting Cells/drug effects/pathology/*secretion, Glucose Intolerance, medicine, Animals, Feeding Behavior/drug effects, Organ Size/drug effects, Signal Transduction/drug effects, Molecular Biology, 030304 developmental biology, Hypoglycemia/complications/metabolism, Cell Biology, Feeding Behavior, medicine.disease, Hypoglycemia, Receptor, Insulin, Insulin receptor, Endocrinology, Gene Expression Regulation, Glucagon-Secreting Cells, Glucose Intolerance/complications, biology.protein, Receptor, Insulin/deficiency/metabolism, Arginine/pharmacology
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المؤلفون: P. A. Antinozzi, Claes B. Wollheim, M. Iezzi, Sten Theander, Haiyan Wang, Philippe A. Halban, Benoit R. Gauthier
المصدر: Diabetologia, Vol. 48, No 4 (2005) pp. 720-731
مصطلحات موضوعية: Time Factors, Adenosine Triphosphate/metabolism, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Prohormone, Gene Expression, Homeodomain Proteins/genetics/metabolism/ physiology, Trans-Activators/genetics/metabolism/ physiology, Adenosine Triphosphate, Gene Expression/drug effects/genetics, Glucokinase, Insulin Secretion, Cyclic AMP, Receptors, Glucagon, Cyclic AMP/metabolism, Exocytosis/physiology, Insulin, Proinsulin, ddc:616, Regulation of gene expression, Human Growth Hormone, Signal Transduction/ physiology, Human Growth Hormone/genetics/secretion, Mitochondria, Gene Expression Regulation, Neoplastic, Doxycycline, Proprotein Convertases, Beta cell, Insulin/ secretion, Glycolysis, hormones, hormone substitutes, and hormone antagonists, medicine.drug, Signal Transduction, medicine.medical_specialty, endocrine system, RNA, Messenger/genetics/metabolism, Glucokinase/genetics, Calcium Signaling/physiology, Biology, Transfection, digestive system, Exocytosis, Glucagon-Like Peptide-1 Receptor, Doxycycline/pharmacology, Proinsulin/ metabolism, Receptors, Glucagon/genetics/ physiology, Receptors, Fibroblast Growth Factor/genetics, Islets of Langerhans, Internal medicine, Cell Line, Tumor, Mitochondria/metabolism, Internal Medicine, medicine, Animals, Secretion, Calcium Signaling, RNA, Messenger, Receptor, Fibroblast Growth Factor, Type 1, Transcription factor, Glucagon-like peptide 1 receptor, Homeodomain Proteins, Dose-Response Relationship, Drug, Islets of Langerhans/drug effects/metabolism, Receptor Protein-Tyrosine Kinases/genetics, Receptor Protein-Tyrosine Kinases, Receptors, Fibroblast Growth Factor, Rats, Endocrinology, Glucose, Gene Expression Regulation, Neoplastic/drug effects, Mutation, Trans-Activators, Glucose/metabolism/pharmacology, Proprotein Convertases/genetics
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المؤلفون: Benoit R. Gauthier, Haiyan Wang, Claes B. Wollheim, Mariella Iezzi, Kerstin A. Hagenfeldt-Johansson
المصدر: Journal of Biological Chemistry, Vol. 277, No 20 (2002) pp. 17564-70
مصطلحات موضوعية: medicine.medical_treatment, RNA, Messenger/metabolism, Fluorescent Antibody Technique, Biochemistry, chemistry.chemical_compound, Mice, 0302 clinical medicine, Hexokinase, Phosphoproteins/genetics, Glucokinase, Tumor Cells, Cultured, Insulin, Glucose homeostasis, Homeostasis, Glycolysis, Hepatocyte Nuclear Factor 1-alpha, reproductive and urinary physiology, 0303 health sciences, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, Nuclear Proteins, Glucose/physiology, respiratory system, DNA-Binding Proteins, Hepatocyte Nuclear Factor 4, Multigene Family, embryonic structures, Hepatocyte Nuclear Factor 1, Hepatocyte Nuclear Factor 3-beta, PDX1, Multigene Family/physiology, Transcriptional Activation, medicine.medical_specialty, endocrine system, DNA-Binding Proteins/genetics/physiology, Glucokinase/biosynthesis/genetics/metabolism, Transcription Factors/genetics, Biology, Nuclear Proteins/genetics/physiology, Glucagon, 03 medical and health sciences, Internal medicine, medicine, Animals, RNA, Messenger, Glucagon/genetics, Potassium Channels, Inwardly Rectifying, ddc:612, Molecular Biology, Insulin/physiology, 030304 developmental biology, Hepatocyte Nuclear Factor 1-beta, Cell Biology, Phosphoproteins, Rats, Glucose, Endocrinology, chemistry, Gene Expression Regulation, biology.protein, Potassium Channels, Inwardly Rectifying/genetics, GLUT2, 030217 neurology & neurosurgery, Hexokinase/biosynthesis/genetics, Transcription Factors
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71aa8aca0492aeafc48c72248b80a537
https://archive-ouverte.unige.ch/unige:34554 -
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المؤلفون: Nicolas Damond, Paolo Meda, Simona Chera, Andreas Wiederkehr, Bernard Thorens, Claes B. Wollheim, Pedro Luis Herrera, Fabrizio Thorel
المصدر: Diabetes
Diabetes, vol. 60, no. 11, pp. 2872-2882
Diabetes, Vol. 60, No 11 (2011) pp. 2872-82مصطلحات موضوعية: Male, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Streptozocin/toxicity, Apoptosis, Cell Count, Glucagon/blood/genetics/metabolism, Hyperglycemia/chemically induced/prevention & control, Tamoxifen/pharmacology, Mice, 0302 clinical medicine, Insulin-Secreting Cells, Receptors, Glucagon, Receptors, Glucagon/metabolism, Insulin, Glucose homeostasis, ddc:576.5, Diphtheria Toxin, Promoter Regions, Genetic, 0303 health sciences, Selective Estrogen Receptor Modulators/pharmacology, Insulin-Secreting Cells/drug effects/metabolism/pathology/secretion, medicine.anatomical_structure, Intercellular Signaling Peptides and Proteins/genetics/metabolism, Intercellular Signaling Peptides and Proteins, Diphtheria Toxin/toxicity, Signal transduction, Pancreas, Heparin-binding EGF-like Growth Factor, Signal Transduction, Pancreas/drug effects/metabolism/pathology, Selective Estrogen Receptor Modulators, Genetically modified mouse, medicine.medical_specialty, Animals, Apoptosis/drug effects, Diabetes Mellitus, Experimental/blood, Diabetes Mellitus, Experimental/chemically induced, Glucagon/blood, Glucagon/genetics, Glucagon-Secreting Cells/drug effects, Glucagon-Secreting Cells/metabolism, Hyperglycemia/chemically induced, Hyperglycemia/prevention & control, Hypoglycemia/prevention & control, Insulin/blood, Insulin/metabolism, Insulin-Secreting Cells/drug effects, Insulin-Secreting Cells/metabolism, Intercellular Signaling Peptides and Proteins/genetics, Intercellular Signaling Peptides and Proteins/metabolism, Mice, Transgenic, Pancreas/drug effects, Pancreas/metabolism, 030209 endocrinology & metabolism, Biology, Hypoglycemia, Glucagon, Streptozocin, Diabetes Mellitus, Experimental, 03 medical and health sciences, Insulin/blood/metabolism, Internal medicine, Internal Medicine, medicine, ddc:612, 030304 developmental biology, Glucagon-Secreting Cells/drug effects/metabolism/pathology/secretion, Diabetes Mellitus, Experimental/blood/chemically induced/metabolism/pathology, medicine.disease, Tamoxifen, Endocrinology, Islet Studies, Glucagon-Secreting Cells, Hyperglycemia
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